肌少症影响因素Meta分析

目的 通过Meta分析系统评价肌少症的影响因素,为该病的预防提供循证依据.方法 计算机检索中国知网(CNKI)、万方数据库(WanFang Data)、维普中文期刊数据库(VIP)、中国生物医学文献数据库(SinoMed)、PubMed、Embase、Web of science和Cochrane图书馆,收集文献时间为...     

维持性血液透析患者肌少症患病率的meta分析

目的 系统评价维持性血液透析患者骨骼肌减少症（肌少症）的患病率情况。方法 全面检索中英文数据库:中国知网（CNKI）、中国生物医学文献数据库（CBM）、万方数据库（Wanfang Date）、维普数据库（VIP）,英文数据库Pubmed、Embase、web of science、EBSCO查找有关维持性血液透析患者肌少症患病情况的相关研究。对纳入的文献按照纳排标准进行筛选、提取所需数据并按照标准严格进行文献质量评价后,通过Stata 12.0软件进行meta分析。结果 本研究最终纳入了15篇文献,共计2 561例维持性血液透析患者,文献质量评价均为中高等质量文献。Meta分析结果显示,维持性血液透析患者肌少症总患病率为31.2%（95%CI:24.9%～37.6%）,亚洲患者患病率为31.8%（95%CI:24.0%～39.6%）。男性肌少症患病率较女性患者高（37.0% vs 28.0%）,使用AWGS诊断标准肌少症患病率高于EWGSOP诊断标准（36.8% vs 26.2%）,使用DEXA肌量评估方法肌少症患病率稍低于BIA肌量评估方法（29.2% vs 32.0%）。结论 维持性血液透析患者肌少症患病率较高,需开展干预研究。     

认识老年肌少症

<正>肌量和肌力在人的一生中是不断变化的,在青壮年时达到最高水平,超过50岁后,腿部肌量每年减少1%～2%.肌力每年减少1.5%～5%。肌少症是以骨骼肌质量和功能随年龄增长而减少的疾病。肌少症的患病率、发病机制及危害     

社区老年人肌少症患病率及影响因素的meta分析

目的 分析社区老年人肌肉减少症（肌少症）的患病率及影响因素。方法 检索PubMed、Embase、The Cochrane Library、Web Of Science、CINAHL、维普数据库、中国知网、万方数据库、中国生物医学文献服务系统等数据库从建库至2021年7月关于社区老年人肌少症患病率及影响因素的相关文献,采用RevMan 5.3软件对社区老年人肌少症患病率及影响因素进行meta分析。结果 共纳入19篇横断面研究,老年肌少症人数合计3 883例,社区老年人肌肉减少症总患病率为16%[95%CI(10%～22%)],亚组分析显示,南美洲、城市地区老年人肌少症患病率更高;年龄70～<80岁（OR=3.42,95%CI:1.84～6.43）、年龄≥80岁（OR=11.42,95%CI:6.89～18.92）、吸烟（OR=2.66,95%CI:1.76～4.02）、糖尿病（OR=1.93,95%CI:1.06～3.52）、体质量指数增加（OR=0.71,95%CI:0.67～0.75）、营养不良（OR=3.96,95%CI:2.88～5.44）、女性（OR=2.55,95%C...     

社区老年人身体活动与罹患肌少症的关联

目的  探讨日常身体活动水平和体育锻炼习惯对社区老年人肌少症的影响。 方法  于2019年5月―8月招募≥65岁的老年人,通过亚洲肌少症诊断标准调查社区老年人肌少症患病率。采用自制问卷收集老年人一般人口学资料和生活习惯资料。采用国际体力活动量表（international physical activity questionnaire,IPAQ-s）对老年人日常身体活动量进行评估。使用Logistic回归分析模型分析肌少症与日常身体活动量、锻炼习惯之间的关系。 结果  社区老年人肌少症患病率为12.3%。在调整了人口学特征和生活习惯等混杂因素后,无锻炼习惯老年人肌少症患病率是有锻炼习惯者的2.759倍（OR=2.759,95% CI：1.213~5.919,P=0.017）。坚持锻炼年数每增加1年,老年人罹患肌少症的风险减少0.070（OR=0.930,95% CI：0.878~0.985,P=0.013）。每次锻炼时间增加1 h,老年人罹患肌少症的风险减少0.611（OR=0.389,95% CI：0.187~0.809,P=0.012）。 结论  我国≥65岁老年人肌少症患病率较高。尽早开始每周2 d以上、每次25 min以上的体育锻炼可降低老年人肌少症的患病风险。     

中国社区老年人群营养不良患病率Meta分析

目的对中国社区老年人群营养不良患病率进行Meta分析。方法通过PubMed、Embase、The Cochrane Library、Web of Science、万方数据资源系统、中国期刊全文数据库, 检索2011年8月1日至2021年7月31日的中国地区社区老年人群(≥60岁)营养状况研究的相关文献, 根据不同文献中营养评估筛查工具定义营养不良。拟合随机效应模型计算患病率, 并根据纳入文献数据情况进行亚组分析和组间差异分析。结果共有13篇文献符合纳入标准, 包括19 938名≥60岁的参与者。营养不良诊断标准和界定共计7种方法。文献报告的营养不良患病率水平差异较大(2.4%～52.5%), 其中7篇文献报告了营养不良风险的患病率(21.3%～67.0%)。Meta分析显示, 中国社区老年人群营养不良和营养不良风险合并患病率为41.2%(95%CI:29.5%～54.0%, I2=99.6%, P<0.05), 且2017年后患病率低于2017年以前(29.6%vs. 66.6%, χ2=274.20, P<0.05)、男性低于女性(44.9%vs. 52.2%, χ2=1...     

基于扎根理论的社区肌少症老年人养老服务需求框架构建

目的：基于扎根理论构建社区肌少症老年人养老服务需求框架。方法：通过对云南省大理市某社区的16例肌少症老年人进行访谈,获取其养老服务需求,使用扎根理论研究方法进行编码与分析。结果：共形成101个概念,13个一级范畴,8个二级范畴,建立基于物质性和精神性价值需求的肌少症老年人养老服务需求框架,核心范畴为“给予支持”。结论：为社区肌少症老年人养老服务需求提供了概念框架,可以将该框架结构与社区实际养老相结合,实现智慧养老。     

中国中小学生龋齿患病率Meta分析

了解中国中小学生龋齿流行态势,为学校龋齿防治工作提供科学依据.方法 系统检索PubMed, Web of Science,Embase 和CNKI 等数据库.英文检索词为Dental cariesSchool studentChinaPrevalence,中文检索词为龋齿、中小学生、中国、患病率.同时辅以人工检索参考文献.检索范围为2010年1月至2018年2月.应用随机效应模型计算合并龋患率及其95%CI,按学段、性别、城乡进行亚组分组.结果 纳入文献49 篇,总人数4 526 031 人,龋患人数997 208 例,纳入的研究调查覆盖19 省份,调查时间为2010—2016年.龋患率的中位数为21.56%,P25 ~ P75为15.46%~37.78%.各地龋患率差异较大,其中最低为3.44%,最高为75.80%,各研究间表现为异质性.Meta 分析显示,中国中小学生龋患率为27.11% (95%CI = 24.63%~ 29.59%).亚组分析中,中学生龋患率为20.67%(95%CI = 17.39%~ 23.94%) 低于小学生的28.82%(95%CI = 25.16%~ 32.48%) (RR= 0.73,95%CI = 0.57 ~ 0.93,P<0.01).男生龋患率为27.18%(95%CI = 23.36%~ 31.01%),低于女生的31.60%(95%CI = 27.28%~ 35.91%) (RR = 0.83,95%CI = 0.81 ~ 0.86,P<0.01).城市学生龋患率为32.41%(95%CI = 24.04% ~ 40.78%),低于农村的35.07%(95%CI = 22.46% ~ 47.69%) (RR = 0.90,95%CI = 0.76 ~ 1.06,P= 0.20).结论 龋齿是影响中小学生的主要疾病.应加强中小学生龋齿防治工作,有针对性地进行宣传教育和开展早期预防与干预.     

中国成年人糖尿病患病率Meta分析

目的 采用Meta分析方法了解过去30年我国成年人糖尿病流行情况,为糖尿病的预防和控制提供科学依据。方法 检索中国期刊全文数据库（CNKI）、万方数据资源系统（Wanfang）、维普数据库（VIP）和PubMed数据库截至2017年10月1日收录的所有有关中国多省市糖尿病患病率研究的文献。运用随机效应模型计算合并患病率。若存在异质性,采用连续分段多项式回归模型来估计糖尿病患病率随时间变化趋势。结果 共纳入15篇文献,其中2篇文献因仅包括≥ 40岁人群未纳入主要分析。Meta分析显示,1980-2013年中国成年人糖尿病患病率为6.3%（95%CI：4.6%~8.0%）,城市合并患病率高于农村地区,男性糖尿病合并患病率略高于女性。1980-2013年,我国成年人糖尿病患病率呈非线性增长。2000年前的合并患病率为3.5%（95%CI：2.0%~4.9%）,每年增长约0.17%;2000年后的合并患病率为8.0%（95%CI：6.0%~10.1%）,每年增加约0.72%。结论 中国成年人糖尿病患病率不断升高,且在2000年后迅速增长,需采取积极的策略预防和控制糖尿病。     

社区老年人运动认知风险综合征患病率及相关因素的系统评价和Meta分析

目的 对社区老年人运动认知风险综合征的患病率和相关因素进行系统评价和meta分析。方法 计算机检索Pub Med、Embase、Web of Science、CINAHL、Sino Med、Cochrane Library、Psyc Info、知网、万方和维普等数据库,检索时限为建库至2022年5月。纳入有关社区老年人运动认知风险综合征患病率及其相关因素的研究。横断面研究采用美国卫生保健质量和研究机构推荐的质量评价标准进行评价。队列研究和病例对照研究使用纽卡斯尔-渥太华量表进行质量评价。使用Stata 15.0软件对提取的数据进行meta分析。结果 共纳入16篇文献,涉及51 364例社区老年人。结果显示,社区老年人运动认知风险综合征总患病率为8.0%(95%CI:7.0%～10.0%)。亚组分析结果显示,美洲、亚洲和欧洲患病率分别为8.9%(95%CI:6.9%～10.8%)、9.0%(95%CI:7.2%～10.7%)和5.1%(95%CI:0.1%～10.0%)。中国社区老年人运动认知风险综合征患病率为10.2%(95%CI:7.5%～12.9%)。社区老年人运动认知风险综合征的...     

Prevalence of human leishmaniasis in Sudan: A systematic review and meta-analysis

BACKGROUNDThere are three main forms of leishmaniasis in humans: cutaneous leishmaniasis (CL), visceral leishmaniasis (VL), and mucocutaneous leishmaniasis. The prevalence of human leishmaniasis varies widely in different countries and different regions of the same country. To date, there is no overall estimation of the prevalence of human leishmaniasis in Sudan.AIMTo determine the pooled prevalence of human leishmaniasis and the disease risk factors among Sudanese citizens.METHODSFrom all articles written in English or Arabic languages conducted before the 4th of August 2021 from [Scopus, Web of Science, PubMed, and MEDLINE, African Journals Online (AJOL), ResearchGate, direct Google search, Google Scholar, and universities websites], just 20 articles with a total of 230960 participants were eligible for this study. Data synthesis and analysis were done using STATA software, version 16. EndNote citation manager version X9.3.3 and Reference Citation Analysis (RCA) were used to remove the duplicated studies and manage the citation respectively. RESULTSThe overall pooled prevalence of human leishmaniasis in Sudan was 21% (with confidence interval 12%-30%). CL was the most common type of leishmaniasis in Sudan, with a pooled prevalence of 26% followed by VL (18%). Nevertheless, the pooled prevalence of human leishmaniasis in Sudan was higher in males compared with females (60% vs 40%). The current results revealed that the people in the age group between 15 and 44 were the most affected group (60%), and central Sudan has the highest pooled prevalence of human leishmaniasis (27%) compared with other regions of Sudan. Finally, the prevalence of human leishmaniasis seems to decrease with time.CONCLUSIONThis study showed that human leishmaniasis infection is still endemic in many regions in Sudan and highly prevalent in central and eastern Sudan, and CL is the most prevalent in the country. Males and adults were more susceptible to infection compared with females and children. However, the human leishmaniasis prevalence decreased relatively over time.     

中国儿童注意缺陷多动障碍患病率Meta分析

目的 通过Meta分析了解我国儿童注意缺陷多动障碍（ADHD）患病情况,为早期防治提供科学依据。方法 检索1979－2017年中国期刊全文数据库（CNKI）、万方数据库（Wanfang data）、中国生物医学文献数据库（CBM）、维普数据库（VIP）中有关中国儿童ADHD患病率研究文献,检索1946－2017年PubMed中研究地区在中国的相关文献。根据STROBE声明中横断面研究评价标准进行文献质量评价,利用Stata 12.0软件合并患病率,并对性别、地区、发表年份、诊断方法及抽样方法等因素进行亚组分析,采用Egger检验及漏斗图评估各文献发表偏倚,通过采用不同模型和排除其中任意1篇文献对合并效应值的影响进行敏感性分析。结果 共纳入20篇文献,总样本量88 755人,男童46 216人,女童42 539人。中国儿童ADHD总患病率为5.6%（95% CI：5.0%～6.3%）。亚组分析显示男童患病率7.7%（95% CI：6.7%～8.8%）,女童患病率3.4%（95% CI：3.0%～3.8%）,差异有统计学意义（P<0.05）。不同地区、发表年代、诊断方法和抽样方法之间差异无统计学意义。结论 我国儿童ADHD患病率较高,男童患病率明显高于女童,应采取早筛查、早治疗方案并进行相应干预。     

Prevalence of Sarcopenia Among the Elderly in Korea: A Meta-Analysis

ObjectivesSarcopenia is a common disease in the elderly population that causes disability, poor quality of life, and a high risk of death. In the current study, we conducted a meta-analysis to report basic knowledge about the prevalence of sarcopenia in the elderly in Korea.MethodsWe searched for articles in the MEDLINE, Cochrane Library, Embase, and Scopus databases published until December 28, 2020. Studies investigating the prevalence of sarcopenia in elderly Koreans aged ≥65 years were included. The methodological quality of the studies was evaluated using the Newcastle-Ottawa scale. Publication bias was evaluated using the Egger test and funnel plots.ResultsIn total, 3 studies and 2922 patients were included in the meta-analysis. All 3 studies used the European Working Group on Sarcopenia in Older People criteria for the diagnosis of sarcopenia. The total prevalence of sarcopenia was 13.1-14.9% in elderly men and 11.4% in elderly women.ConclusionsThis meta-analysis is the first to estimate the pooled prevalence of sarcopenia in elderly Koreans, and its findings suggest that sarcopenia is common in this population. Therefore, attention should be paid to the prevention and control of sarcopenia.     

Marital status and mortality in the elderly: a systematic review and meta-analysis

Although a relationship between marital status and mortality has long been recognized, no summary estimates of the strength of the association are available. A meta-analysis of cohort studies was conducted to produce an overall estimate of the excess mortality associated with being unmarried in aged individuals as well as to evaluate whether and to what degree the effect of marriage differs with respect to gender, geographical/cultural context, type of non-married condition and study methodological quality. All included studies were published after the year 1994, used multivariate analyses and were written in English. Pooling 53 independent comparisons, consisting of more than 250,000 elderly subjects, the overall relative risk (RR) for married versus non-married individuals (including widowed, divorced/separated and never married) was 0.88 (95% Confidence Interval: 0.85-0.91). This estimate did not vary by gender, study quality, or between Europe and North America. Compared to married individuals, the widowed had a RR of death of 1.11 (1.08-1.14), divorced/separated 1.16 (1.09-1.23), never married 1.11 (1.07-1.15). Although some evidence of publication bias was found, the overall estimate of the effect of marriage was robust to several statistical approaches and sensitivity analyses. When the overall meta-analysis was repeated with an extremely conservative approach and including eight non-significant comparisons, which were initially excluded because of data unavailable, the marriage protective influence remained significant, although the effect size was reduced (RR=0.94; 0.92-0.95). Despite some methodological and conceptual limitations, these findings might be important to support health care providers in identifying individuals "at risk" and could be integrated into the current programs of mortality risk estimation for the elderly.     

Prevalence of frailty in Japan: A systematic review and meta-analysis

Japan's population is aging more rapidly than that of any other country. Frailty has recently been recognized as an important priority. Understanding the basic epidemiology of frailty in Japan, which is an example of a rapidly aging society, will be beneficial for Japan as well as other countries expecting an aging population. A systematic literature search of 11 electronic databases was conducted in March 2016 using a comprehensive set of Medical Subject Heading and text terms for any studies published in 2000 or later that report the prevalence of frailty among Japanese community-dwelling older people aged 65 years or older. A total of 1529 studies were identified in the systematic search, of which five studies were included in this review. The pooled prevalence of frailty, prefrailty, and robustness was 7.4% (95% confidence interval [CI], 6.1%–9.0%), 48.1% (95% CI, 41.6%–54.8%), and 44.4% (95% CI, 37.2%–51.7%), respectively. A significant degree of heterogeneity was observed. There was no evidence of publication bias. Age-stratified meta-analyses of four studies showed the pooled prevalence of frailty was 1.9%, 3.8%, 10.0%, 20.4%, and 35.1% for those aged 65–69, 70–74, 75–79, 80–84, and ≥85 years, respectively. Pooled prevalence of frailty was 8.1% for women and 7.6% for men. This review showed an overall pooled prevalence of frailty among Japanese community-dwelling older people of 7.4%. The age-stratified analysis suggested that Japanese older people are less frail before their late 70's but frailer in later life than older people in other countries. These findings provide important basic information for all parties involved in Japanese frailty research.