Colitis cystica profunda

Colitis cystica profunda, although rare in occurrence, deserves recognition as a distinct pathologic entity. Several types of clinical presentation have been recognized, the most common being a solitary lesion in the rectum. The cause is generally ascribed to the reparative process associated with chronic mucosal inflammation. Differentiation of this entity from mucus-producing adenocarcinoma should be possible with an adequate biopsy. Conservative excision is appropriate therapy, depending on the clinical manifestations.     

Colitis cystica profunda simulating rectal carcinoma. A case report

A case of colitis cystica profunda, the patient presenting with haematochezia and a rectal mass, is reported. The clinical and pathological features of this condition are discussed, and the difficulty in distinguishing this lesion from the much commoner rectal neoplasms is emphasised.     

Colitis cystica profunda lokalisata

A 33-year-old man had a three-year history of ulcerative colitis. After 14 months of treatment he developed localized colitis cystica profunda mimicing a stenosating cancer of the rectum. The process developed over a short period. The diagnosis is based on a histological examination revealing benign submucosal cysts lined by columnar epithelium. A conservative surgical attitude is recommended.     

Colitis cystica profunda simulating rectal carcinoma

Localized colitis cystica profunda is a rare, benign disease of the lower gastro-intestinal tract, usually presenting as a rectal mass and characterized microscopically by the presence of mucus-filled cysts in the submucosa. Knowledge of this particular pathological entity is important as it can mimic a well differentiated adenocarcinoma of the rectum and therefore could lead to unnecessary surgical resection. We present a case of colitis cystica profunda misdiagnosed as adenocarcinoma based on their similar clinical picture and histological features.     

Colitis cystica profunda: an unusual surgical problem.

Colitis cystica profunda is a rare, benign, non-neoplastic condition which usually presents as a mass in the rectum associated with bloody, mucoid diarrhea. This clinical presentation associated with the microscopic finding of mucus cysts in the submucosa has led to the mistaken diagnosis of adenocarcinoma of the rectum and unnecessarily radical operative procedures. Attention to the completely normal cellular architecture provides the key to the correct diagnosis. Local excision is curative, and there is no propensity to develop malignancy in these patients. Experience with one case is reported, and the medical literature on the subject is reviewed.     

Stromal tumors of the rectum: a case report and review of the literature

This paper describes a case of epithelioid leiomyosarcoma of the rectum in a patient admitted for constipation and rectal bleeding. After an initial biopsy diagnosis of leiomyoma, a local excision was performed, showing the malignant nature of the tumour. Consequently, the patient underwent an abdomino-perineal amputation, adjuvant radiation (50 Gy) and a 24-month follow-up, which revealed no signs of local or distant recurrence. Sarcomas of the rectum are rare and therefore poorly documented neoplasms. They belong to the wider group of gastrointestinal stromal tumours, which are classified in 4 histological types: (i) smooth muscle, (ii) neural, (iii) mixed and (iv) undifferentiated. Since they grow within the intestinal wall, the symptoms are usually few or late, leading to delays in diagnosis. The diagnostic and staging protocol of stromal tumours of the rectum includes CT and MRI. The treatment is primarily surgical, where possible, and should guarantee complete clearance of the tumour, which often requires an aggressive approach. Non-curative resection, high tumour grade and size > 10 cm, are considered unfavourable prognostic factors. Further trials are needed to establish the exact role of adjuvant therapy. Though it prolongs the disease-free interval, there is no clear evidence that it influences the overall survival.     

Primary lymphoma of the rectum: a case report and review of the literature

A case of primary malignant lymphoma of the rectum is presented and the literature reviewed. The authors recommend a complete diagnostic evaluation to assess the unifocal nature of the tumour and stage it, as well as in order to exclude systemic disease. Surgical therapy combined with chemo- and radiotherapy is the best choice when the disease is confined to the rectum, with a better prognosis than those cases treated by chemo- and radiotherapy alone. Because of the extreme rarity of the disease it is impossible to find randomised studies and any evaluation of prognosis can only be done on the basis of the small case series reported in the literature.     

Radiation‐induced angiosarcoma of the rectum: a case report and review of literature

We report a case of rectal angiosarcoma after prostatic radiotherapy, illustrating diagnostic difficulty. Awareness of this potential diagnosis is important with increasing use of radiotherapy in the treatment of pelvic cancers.     

Ureteritis cystica: a case report

This is a case report on a patient with left renal stone and ureteritis cystica. The patient was a 57-year-old male, and he was admitted for a thorough examination of his renal stone. Many sharply-defined radiolucent filling defects were detected in the upper and middle ureter by retrograde pyelography, and he was diagnosed with ureteritis cystica. Since the patient had severe renal function damage, left nephro-ureterectomy was performed. This is the 29th case of pyeloureteritis cystica reported in Japan, and here in its clinical aspects are discussed.     

Pyeloureteritis cystica: report of a case

A 68-year-old female patient was admitted for the examination of duplication of right ureter and right hydronephrosis. Antegrade pyelography showed multiple, small, round defects in the ureter from the upper pole of right kidney. Ureteroureterostomy was performed under the diagnosis of ureteritis. Including our case, 25 cases of pyeloureteritis cystica have been reported in Japan.     

Jejunitis cystica profunda in a hamartomatous polyp. Report of a case

A patient with a history of abdominal discomfort and rectal bleeding was discovered to have two hamartomatous polyps, one of the jejunum and one of the colon. The former was associated with mucinous cysts at its base. The findings were similar to those described for colitis cystica profunda. This case is a rare example of cystica profunda disease of the small bowel. Uniquely, it was associated with a hamartomatous polyp.