稳定型圆锥角膜患者植入新型Phakic角膜接触镜的视觉效果分析

目的：评估可植入式Phakic角膜接触镜治疗稳定型圆锥角膜患者的疗效、安全性、稳定性和可预测性。

方法：共14例患者采用植入式Phakic角膜接触镜(IPCL)矫正屈光不正,测量了未矫正视力、最佳矫正视力、离焦曲线、对比敏感度、屈光度及可能的副作用。评估结果超过6mo。

结果：平均等效球镜度(SE)和散光在术后6mo末次检查时由术前-6.94±2.79 DS和-4.24±1.42 DC分别变为术后-0.23±0.43 DS和-1.05±0.49 DC。术前平均Snellen视力为0.18±0.10。6mo内未矫正视力和最佳矫正视力平均值分别为0.13±0.10和0.05±0.15。平均安全指数为1.11。所有眼视力均无降低,其中22眼视力提高超过1行。20眼(71.4%)屈光度在0.50 D以内,27眼(96.42%)在±1.00 D以内。术后1wk至6mo,屈光度变化为-0.23±0.43(范围： -1.00至+0.75)。6mo内角膜内皮细胞(ECL)丢失率小于5%。术后6mo眼压(IOP)为11.32±2.28 mmHg。

结论：Toric植入式Phakic角膜接触镜在矫正与稳定圆锥角膜相关的近视和近视散光方面具有有效性、安全性和可预测性。     

Visual and refractive outcomes of posterior chamber phakic IOL in stable keratoconus

We evaluated the visual and refractive outcomes after phakic visian toric implantable collamer lens (ICL) insertion in stable keratoconus (KC). This retrospective study investigated toric ICL implantation in 14 eyes of 8 patients with stable KC. After 6mo, the mean uncorrected distance visual acuity improved significantly from 0.77 to 0.15 logMAR. The mean best corrected distance visual acuity (BCDVA) improved from 0.18±0.1 to 0.15±0.1 logMAR. Fifty percent of eyes maintained their preoperative BCDVA; 42.8% gained one line. There was no statistical difference in high order or coma aberration. The mean refractive manifest spherical equivalent (MSE), mean refractive manifest spherical error, mean manifest astigmatism decreased significantly postoperatively. At 6mo postoperatively, our achieved mean spherical equivalent was approximately 74%. No intraoperative or postoperative complications occurred. Toric ICL implantation was effective, predictable and safe to correct refractive error and improve visual acuity in patients with stable KC.     

The refractive outcome of Toric Lentis Mplus implant in cataract surgery

AIM: To evaluate the refractive outcome of Toric Lentis Mplus intraocular lens (IOL) implant. METHODS: This is a retrospective case series. Consecutive patients with corneal astigmatism of at least 1.5 D had Toric Lentis Mplus IOL implant during cataract surgery. The exclusion criteria included irregular astigmatism on corneal topography, large scotopic pupil diameter (>6 mm), poor visual potential and significant ocular comorbidity. Postoperative manifest refraction, uncorrected distance visual acuity (UDVA), best-corrected distance visual acuity (BCVA), uncorrected intermediate visual acuity (UIVA) at 3/4 m and uncorrected near visual acuity (UNVA) were obtained. RESULTS: There were 70 eyes from 49 patients in this study. Patients were refracted at a median of 8.9wk (range 4.0 to 15.5) from the operation date. Sixty-five percent of eyes had 6/7.5 (0.10 logMAR) or better, and 99% 6/12 (0.30 logMAR) or better postoperative UDVA. Eighty-nine percent could read Jaeger (J) 3 (0.28 logMAR) and 95% J5 (0.37 logMAR) at 40 cm. The median magnitude of astigmatism decreased from 1.91 D to 0.49 D (Wilcoxon, P<0.001) after the operation. The range of the cylindrical error was reduced from 1.5-3.95 D (keratometric) preoperatively to 0.00-1.46 D (subjective refraction transposed to corneal plane) postoperatively. CONCLUSION: Toric Lentis Mplus IOL has good predictability in reducing preexisting corneal astigmatism.     

Comparison of clinical outcomes of astigmatic correction using toric intraocular lens

AIM: To compare the clinical effects of two brands of Toric intraocular lens used in surgical correction of cataract with corneal astigmatism. METHODS: Totally 35 patients (50 eyes) with corneal astigmatism who underwent ophthalmic surgery from April 2019 to July 2019 were retrospectively analyzed. Among them, 25 eyes of 20 patients were implanted with Rayner 623T, while 25 eyes of 15 patients with Alcon AcrySof Toric intraocular lens (IOL). Three months after surgery, the uncorrected distance visual acuity (UCDVA), best corrected distance visual acuity (BCDVA), residual astigmatism, rotational degree of intraocular lens, contrast sensitivity, objective visual quality and the National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) scale score were compared. Vector analysis was performed using the Alpins method. RESULTS: The mean postoperative UCDVA and BCDVA (logMAR) in the Rayner group were 0.17±0.20 and 0.08±0.15, respectively (P>0.05), while those in the Alcon group were 0.21±0.16 and 0.10±0.11, respectively (P>0.05). The mean residual astigmatism in the Rayner group was -0.57±0.24 D while that in the Alcon group was -0.50±0.28 D (P>0.05). There was no statistically significant difference between the two groups in IOL rotational stability, vector analysis parameters, contrast sensitivity and objective visual quality (P>0.05). The NEI VFQ-25 scale score was 85.16±5.91 in the Rayner group while it was 82.08±6.16 in the Alcon group (P>0.05). CONCLUSION: The two brands of toric intraocular lens-Rayner 623T and Alcon AcrySof toric show no significant difference in their clinical outcomes.     

AcrySof Toric人工晶状体植入矫正角膜散光的疗效

目的：评价AcrySof Toric人工晶状体(intraocular lens,IOL)植入矫正伴有规则性角膜散光白内障患者的临床效果及IOL的旋转稳定性。

方法：随机选取南京医科大学第一附属医院眼科2012-06/2013-12的白内障合并规则角膜源性散光患者23例28眼行超声乳化白内障摘除联合AcrySof Toric IOL植入术者,观察术后裸眼视力(UCVA),最佳矫正视力(BCVA),以及统计术前预期残余散光与术后实际残余散光,Toric IOL在囊袋内的旋转度。

结果：术后3mo UCVA为0.75±0.16, BCVA为0.84±0.15,BVCA与UCVA比较差异无统计学意义(t=1.036,P>0.05)。术前预期残余散光为0.28±0.12D ,术后3mo实际残余散光为0.42±0.17D,预期散光值与实际残余散光值比较,差异无统计学差异(t=1.259,P>0.05); Toric IOL术后1d IOL平均旋转3.02°±1.56°(0°～7°),术后3mo平均旋转3.28°±1.85°(0°～7°),其中 25眼(89%)旋转<5°,3眼(11%)旋转5°～7°。

结论：Toric IOL植入能够稳定并且有效地矫正白内障患者的角膜散光,并有较精准的散光矫正预测性。     

Phakic toric Implantable Collamer Lens implantation for the correction of high myopic astigmatism in eyes with keratoconus

PURPOSE: To present two patients in whom phakic toric Implantable Collamer Lenses (toric ICL, STAAR Surgical) have been effective for the correction of high myopic astigmatism with stable keratoconus. METHODS: Both patients had a history of contact lens intolerance, and refraction and corneal topography were stable for 3 to 4 years. Preoperatively, the manifest refraction was -10.00 -6.00 x 100 in case 1 and -8.00 -2.75 x 100 in case 2. RESULTS: Postoperatively, the manifest refraction was +0.50 -1.00 x 90 in case 1 and -0.25 -1.25 x 100 in case 2. Uncorrected visual acuity and best spectacle-corrected visual acuity were markedly improved after implantation in both patients. No progressive sign of keratoconus was seen during 1-year follow-up. CONCLUSIONS: Phakic toric ICL implantation may be an alternative for the correction of high myopic astigmatism in eyes with stable keratoconus.     

【In Press】 Five-year follow-up of combined non-topography guided photorefractive keratectomy and corneal collagen cross linking for keratoconus

AIM: To evaluate the visual outcomes of simultaneous non-topography guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) in eyes with keratoconus 5 y after the procedure. METHODS: Prospective, interventional, non-randomized, and non-controlled case series design was used. Sixty eyes of 30 patients (16 males and 14 females; age: 21-41y) with mild, non-progressive (stages 1-2) keratoconus were enrolled. Refraction, uncorrected (UDVA) and corrected (CDVA) distance visual acuities, flat and steep keratometry (K) readings, and adverse events were evaluated preoperatively and postoperatively. Data were collected preoperatively and postoperatively at 3-months, 1-, 2-, 3-, 4-, and 5-year follow-up visits after combined non-topography-guided PRK with CXL was performed. All patients had at least 5y of follow-up. RESULTS: All study parameters showed a statistically significant improvement at 5y over baseline values. The mean follow-up time was 68.20±4.71mo (range: 60-106mo). Patients showed a significant improvement in UDVA from 1.24±0.00 logMAR prior to combined non-TG-PRK+CXL to 0.06±0.00 logMAR postoperatively at the time of their last follow-up visit. CDVA significantly increased from 0.06±0.00 logMAR preoperatively to 0.03±0.00 logMAR postoperatively. A significant decrease in the mean spherical equivalent (SE) refraction was observed from -2.28±1.8 to -0.79±0.93 diopters (D) (P<0.05), and the mean cylinder decreased from -1.628±0.76 (preoperative) to -0.25±0 (postoperative) (P=0.001). The mean keratometry was 45.13±0.00 vs 47.28±0.00 D preoperatively (P<0.05), and the manifest astigmatism significantly decreased from -1.63±0.76 to -0.25±0 (P=0.001). CONCLUSION: Combined non-topography-guided PRK with 15min is an effective and safe option for correcting mild refractive error and improving visual acuity in patients with mild stable keratoconus.     

Refractive outcomes after V4c Toric collamer lens implantation over 1y of follow-up

AIM: To evaluate refractive outcomes and corneal astigmatism changes after Toric implantable collamer lens with a central port (V4c T-ICL) implantation over 1y of follow-up. METHODS: A retrospective study was performed including 50 eyes of 50 patients that underwent V4c T-ICL implantation. Uncorrected (UDVA) and corrected (CDVA) distance visual acuities, refraction, refractive and corneal astigmatism changes and corneal coupling correction were evaluated preoperatively, 1 and 12mo postoperatively. Vector analysis was used for astigmatism changes. Coefficient of adjustment (CAdj) was calculated for corneal coupling analysis. RESULTS: The mean UDVA achieved was 0.03 logMAR at 1mo and remained unchanged throughout the whole follow-up (P=0.193). At the last visit, 84% of the eyes achieved a CDVA of 0.00 logMAR or better. Regarding spherical equivalent refraction (SEQ), 96% of eyes were ranges of ±1.00 D and 84% of them within ±0.50 D. Also, 94% of eyes had a remaining refractive cylinder within ±1.00 D and 78% of them within ±0.50 D. Both, SEQ and refractive cylinder, remain stable over the postoperative follow-up (P=1.000 and P=0.660, respectively). In terms of surgically induced astigmatism (SIA), no statistically significant differences were found over the follow-up (P=0.102) and under correction was found with a correction index lower than the unit at each visit. A keratometric astigmatism induced of 0.59±0.53 (vector mean: 0.26×73º) D was reached at the last visit. No significant changes in terms of corneal astigmatism orientation were reported over post-surgery visits (P=0.129 and P=0.097 at 1 and 12mo respectively). No clinical significance was found for CAdj on with-the-rule astigmatism. No postoperative complications resulting from the surgery were found. CONCLUSION: Refractive outcomes suggest that the V4c T-ICL implantation for correction of myopic astigmatism was satisfactory in terms of effectiveness, safety, and stability during 1y of follow-up. Corneal astigmatism induced by the incision around 0.5 D is achieved according to the remaining refractive cylinder found at one-year post-surgery. Corneal coupling analysis results in no unexpected spherical change.     

AcrySof IQ Toric人工晶状体植入矫正角膜散光的疗效

目的：评价白内障手术中植入AcrySof IQ Toric散光型人工晶状体矫正角膜散光的效果及人工晶状体在囊袋内的稳定性。

方法：对21例26眼伴有角膜规则散光的白内障患者,植入AcrySof IQ Toric散光型人工晶状体,观察术前及术后裸眼视力、最佳矫正视力; 术前角膜散光、预计散光、总散光,术后角膜散光及残余散光; 以及术后人工晶状体旋转度。

结果：术后所有患者裸眼视力及最佳矫正视力均明显提高; 术后残留散光0.55±0.33D,与术前总散光2.05±0.57D相比明显下降(t=13.574,P<0.05); 与术前预留散光0.47±0.19D比较无统计学意义(t=1.149,P>0.05)。术后3mo角膜散光-1.89±0.53D,与术前角膜散光2.01±0.58D相比无差异(t=1.908,P>0.05); 所有26眼的人工晶状体旋转度均<20°,平均旋转为(3.65±2.86)度。

结论：白内障超声乳化吸除联合AcrySof IQ Toric IOL植入矫正散光手术,能够有效的减少患者的散光,术后IOL旋转稳定性良好,是治疗白内障合并散光患者的有效的手术方法。     

Partial Visual Rehabilitation Using a Toric Implantable Collamer Lens in a Patient with Keratoconus: A Case Report with 20 Months of Follow-up

We report the case of a 37-year-old man with a high myopic keratoconus eye that was treated with a posterior chamber toric implantable collamer lens (ICL) in Korea. The patient had a history of contact lens intolerance and did not want to have a corneal transplantation. His uncorrected visual acuity (UCVA) and best spectacle corrected visual acuity were 0.02 and 0.4 in the left eye, respectively. Preoperatively, the manifest refraction was -12.0 -3.5 × 30A. Postoperatively, the manifest refraction was -1.75 × 180A. UCVA improved markedly after implantation. No intraoperative or postoperative complications were observed during 20 months of follow-up. Toric ICL implantation may be a possible alternative surgical option for the visual rehabilitation of high myopic astigmatism in keratoconus patients with rigid gas permeable contact lens intolerance and in patients who do not want to get a corneal transplant.     

有晶状体眼后房散光型IOL植入矫正高度近视散光

目的：评价有晶状体眼后房散光型人工晶状体(TICL)植入术矫治高度近视散光的临床效果。

方法：选自2009-10/2011-11接受TICL植入的高度近视散光患者30例50眼,术前平均屈光度球镜-10.75±2.65D,柱镜-2.85±0.75D。随访观察术后3mo～2a裸眼视力、最佳矫正视力、屈光度、内皮细胞计数等情况,分析并发症的发生情况。

结果：术后裸眼视力：0.5～1.2(平均0.75±0.34)。术前最佳矫正视力：0.3～1.0(平均0.58±0.35),术后最佳矫正视力0.6～1.2(平均0.78±0.35)。达到术前矫正视力20眼(40%),超过术前最佳矫正视力30眼(60%),随访3mo～2a,视力无明显变化。术后屈光度数平均球镜-0.52±0.35D,柱镜0.52±0.25D。角膜内皮细胞计数术前3 026±250个/mm²,术后3mo为3 023±246个/mm²,差异无统计学意义(P<0.05)。未见严重影响视力的并发症。

结论：TICL植入矫治高度近视散光安全有效,是高度近视散光患者的理想治疗方法。对眼内的长期影响需要进一步观察。     

5-year follow-up of combined non-topography guided photorefractive keratectomy and corneal collagen cross linking for keratoconus

AIM: To evaluate the visual outcomes of simultaneous non-topography guided photorefractive keratectomy (PRK) and corneal collagen cross-linking (CXL) in eyes with keratoconus 5y after the procedure. METHODS: Prospective, interventional, non-randomized, and non-controlled case series design was used. Sixty eyes of 30 patients (16 males and 14 females; age: 21-41y) with mild, non-progressive (stages 1-2) keratoconus were enrolled. Refraction, uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA) , flat and steep keratometry readings, and adverse events were evaluated preoperatively and postoperatively. Data were collected preoperatively and postoperatively at 3mo, 1, 2, 3, 4, and 5y follow-up visits after combined non-topography-guided PRK with CXL was performed. All patients had at least 5y of follow-up. RESULTS: All study parameters showed a statistically significant improvement at 5y over baseline values. The mean follow-up time was 68.20±4.71mo (range: 60-106mo). Patients showed a significant improvement in UDVA from 1.24±0.79 logMAR prior to combined non-TG-PRK+CXL to 0.06±0.15 logMAR postoperatively at the time of their last follow-up visit. CDVA significantly increased from 0.06±0.19 logMAR preoperatively to 0.03±0.12 logMAR postoperatively. A significant decrease in the mean spherical equivalent (SE) refraction was observed from -2.28±1.8 to -0.79±0.93 diopters (D) (P<0.05), and the manifest sphere decreased from -1.62±1.23 to -0.27±0.21 D (P=0.001). The manifest cylinder significantly decreased from -1.73±0.86 to -0.29±0.34 D postoperatively (P=0.001). The mean steep keratometry was 45.13±1.32 vs 47.28±2.12 D preoperatively (P<0.05), and the preoperative mean steepest keratometry (Kmax) 48.6±3.1 was reduced significantly to 46.8±2.9 postoperatively (P<0.05). CONCLUSION: Combined non-TG-PRK with 15min CXL is an effective and safe option for correcting mild refractive error and improving visual acuity in patients with mild stable keratoconus.     

双焦点Toric人工晶状体植入矫正白内障合并角膜散光的疗效观察

目的:评价白内障超声乳化吸除联合双焦点Toric人工晶状体(IOL)植入术的散光矫正临床效果。方法:回顾性分析。纳入2020-08/2021-09间我院白内障超声乳化吸除联合双焦点Toric IOL治疗白内障合并角膜规则散光患者46例46眼的临床资料。术后随访3mo,评价术前及术后1、3mo裸眼远视力(UDVA)、裸眼近视力(UNVA)、矫正远视力(BCDVA)、矫正近视力(BCNVA)及散光的变化。测量并计算IOL轴位旋转度,行问卷调查在不同距离使用眼镜的必要性以及总体满意度。结果:术后1、3mo UDVA、BCDVA、UNVA、BCNVA与术前比较均有差异(均P<0.001),而术后1mo UDVA、BCDVA、UNVA、BCNVA与术后3mo比较均无差异(均P>0.0167)。术后3mo UDVA达到0.20(LogMAR)者46眼(100%),UNVA达到0.20(LogMAR)者40眼(87%)。散光矢量分析显示,术前角膜散光均值为1.88±0.70D,质心值为0.61D@177°±1.93D,术后3mo残余散光均值为0.33±0.30D,质心值为0.03D@34...     

圆锥角膜患者使用Rose K2软性角膜接触镜的临床表现

目的:评价圆锥角膜患者使用Rose K2软性角膜接触镜的舒适度及视觉表现.方法:横断面研究.50例患者(50眼)接受全面的眼科检查,包括屈光度、裸眼视力(UCVA)、最佳矫正视力(BCVA)、裂隙灯显微镜及眼底检查、泪膜破裂时间(BUT)、角膜地形图和对比敏感度.戴镜后,测量最佳戴镜矫正视力(BCLCVA)、对比敏感度及舒适度通过平均视觉模拟量(VAS)呈现.结果:患者平均年龄为26.2依6.0 (16 ~39) y.使用Rose K2软性角膜接触镜 UCVA,BCVA,和 BCLCVA 的平均logMAR值依次为0.61依0.37 (0.15 ~1.3),0.42依0.32 (0~1.3) 和0.18依0.20 (0 ~1.3).使用接触镜后视敏度显著提高(P<0.05),在明视和暗视条件下,对比敏感度数值明显增加(P<0.05).Rose K2软性角膜接触镜的视觉模拟量(VAS)值为8.02依1.64(5~10).结论:圆锥角膜患者使用Rose K2软性角膜接触镜能够改善视力,对比敏感度以及舒适度.     

Toric Intraocular Lens Implantation for Correction of Astigmatism in Cataract Patients with Corneal Ectasia

Our purpose was to examine the long-term efficacy of toric intraocular lens (IOL) implantation in cataract patients with high astigmatism due to corneal ectasia, who underwent phacoemulsification cataract surgery. Five eyes of 3 cataract patients with topographically stable keratoconus or pellucid macular degeneration (PMD), in which phacoemulsification with toric IOL implantation was used to correct high astigmatism, are reported. Objective and subjective refraction, visual acuity measurement and corneal topography were performed in all cases before and after cataract surgery. In all cases, there was a significant improvement in visual acuity, as well as refraction, which remained stable over time. Specifically, in subjective refraction, all patients achieved visual acuity from 7/10 to 9/10 with up to −2.50 cyl. Corneal topography also remained stable. Postoperative follow-up was 18–28 months. Cataract surgery with toric IOL implantation seems to be safe and effective in correcting astigmatism and improving visual function in cataract patients with topographically stable keratoconus or PMD.Key words: Phacoemulsification, Keratoconus, Pellucid marginal degeneration, Toric intraocular lens, Intraocular lens, Astigmatism     

Evaluation of axis alignment and refractive results of toric phakic IOL using image-guided system

AIM: To evaluate accuracy of axis alignment and refractive results of toric phakic intraocular lens(IOL) implantation using a digital imaging system. METHODS: This retrospective study investigated toric implantable collamer lens(ICL) implantation in 30 eyes of 21 patients with myopic astigmatism more than 2.0 D guided with digital imaging system. Data were collected during the first week after phakic IOL implantation.RESULTS: Thirty eyes of 21 patients were included in our study. Patients includes 9 males and 12 females. The mean age of the patients was 26.5±7.1(range 21-44)y. The mean preoperative manifest astigmatism was 3.2±1.7(range from 2.25 to 4.75) D. The mean postoperative uncorrected distance visual acuity(UCDVA) were 0.07±0.07(range from 0.1 to 0.0) log MAR. The mean postoperative residual refractive cylinder was 0.25±0.29(range 0-0.75) D. Eyes with postoperative residual refractive cylinder of 0.5 D or less represented 80%(24 eyes). The mean postoperative toric IOL misalignment measured by the OPD scan III was 1.9°±1.45°(range from 0 to 5°). CONCLUSION: Image guided system allows accurate alignment of toric ICL. This is associated with good postoperative visual acuity and low residual refractive astigmatism which correlates with the precision of toric phakic IOL alignment.     

单切口植入有晶状体眼后房型人工晶状体治疗高度近视

目的：评价单切口有晶状体眼后房型人工晶状体植入术治疗高度近视的有效性和安全性。

方法：对9例18眼高度近视患者行有晶状体眼后房型人工晶状体植入术。术后随访3～9mo,观察手术前后裸眼视力、最佳矫正视力、屈光度、散光变化、眼压、内皮细胞计数等。

结果：所有患者成功植入眼内接触镜(implantable contact lens,ICL),18眼手术前后平均屈光度分别为-13.38±-5.32,

-0.25±0.38D; 手术前后裸眼视力分别为0.06±0.04,0.6±0.2; 最佳矫正视力分别为0.5±0.3,0.7±0.3; 术后裸眼视力和最佳矫正视力均明显好于术前(P<0.05)。术前平均眼压为13.23±3.18mmHg,术后平均眼压为15.03±1.25mmHg; 内皮细胞计数术前为3 008±298个/mm²,术后为2 896±246个/mm²; 前房深度术前平均为3.56±0.29mm,术后为3.68±0.37mm,角膜散光术前0.52±0.30D,术后角膜散光0.67±0.45D,差异均无统计学意义(P>0.05)。

结论：单切口植入有晶状体眼后房型人工晶状体矫正高度近视近期临床效果有效、可靠,具有手术操作风险低、眼表损伤小、成本低、术源性散光小的优点,为一种适用的手术方式。     

Combination of Toric and multifocal intraocular lens implantation in bilateral cataract patients with unilateral astigmatism

AIM: To assess the binocular visual function in bilateral cataract patients with unilateral astigmatism after combined implantations of Toric with multifocal intraocular lens (IOL), and to compare with that of Toric and monofocal IOL implantation. METHODS: All the 30 patients with unilateral astigmatism suffered bilateral cataract were randomly divided into two groups: Toric plus multifocal IOL group and Toric plus monofocal IOL group. Uncorrected and corrected visual acuity at distance (5.0 m), intermediate distance (0.6 m), and near (0.33 m), contrast sensitivity, and stereopsis were assessed 6mo after surgery. Patients were also surveyed for visual disturbances and spectacle dependence. RESULTS: Binocular uncorrected visual acuity (LogMAR) of Toric/multifocal IOL eyes at distance, intermediate, near were 0.05±0.05, 0.24±0.10, and 0.14±0.06 respectively. The values of Toric plus monofocal IOL eyes were 0.06±0.07, 0.26±0.08, and 0.37±0.10 respectively. These values did not indicate significant differences between two groups with exception of near visual acuity. In the photopic condition (with or without glare), the contrast sensitivity of multifocal IOL eyes was significant lower than the monofocal IOL eyes in 18 cpd. In the mesopic condition, the contrast sensitivity of multifocal group was significant lower than monofocal group in 12 cpd, and in mesopic glare condition, this significant difference was found both in 6 cpd and 12 cpd. The stereopsis of Toric/multifocal IOL eyes decreased slightly (100±80 seconds of arc, t=2.222, P=0.136). Mean near vision for patient satisfaction was statistically significantly higher in Toric/multifocal IOL group patients versus than that in Toric/monofocal IOL group (80% vs 25.5%, P=0.000). Visual disturbance was not noticed in either group. CONCLUSION: Although the combination of Toric and multifocal IOL implantation results in compromising stereoacuity, it can still provide patients with high levels of spectacle freedom and good overall binocular visual acuity.     

TICL治疗高度近视合并散光疗效分析

目的:研究T优化的后房型人工晶状体(toric implantable contactlens,TICL)矫正高度近视合并散光的效果。方法:本研究中高度近视合并散光患者7例13眼,术前屈光度-9.50～-24.00(平均-14.50±7.43)D,散光范围+1.0～+3.5(平均+2.59±0.38)D,眼轴长度26.20～32.85(平均29.38±3.01)mm。13眼均植入TICL。术后观察视力、屈光度、眼压、人工晶状体位置等。结果:所有病例均成功植入TICL,所有患者裸眼视力均有明显提高,术后1wk,所有术眼达到或超过术前最佳矫正视力,眼压正常,屈光度在术后6mo的随访中稳定。结论:TICL植入有晶状体眼治疗高度近视合并散光安全可靠,术后屈光度稳定,视觉质量提高。     

Toric人工晶状体矫正外伤性白内障患者散光的观察

目的评价Toric人工晶状体矫正外伤性白内障患者散光的效果。方法前瞻性病例研究,收集我科散光大于1．0D的外伤性白内障患者17例（17只眼）,所有患者受伤后角膜缝线已拆除,屈光状态稳定3个月队上,施行白内障超声乳化联合Toric人工晶状体植入术。术后随访3～28个月,观察手术前后裸眼视力（uncorrected visual acuity,UCVA）、最佳矫正视力（best corrected visual acuity,BCVA）、散光（包括角膜源性散光及总合散光）、人工晶状体位置、术中及术后并发症等情况。结果术后UCVA及BCVA均较术前提高,差异有统计学意义（P〈0．05）,术后UCVA≥0．6者11例,所有患者BCVA≥0．6,BCVA≥1．0者8例;术后球镜度数及总合散光均较术前降低,差异有统计学意义（P〈0．05）;手术前后角膜源性散光变化无统计学意义。人工晶状体具有良好的居中性,随访末期,旋转度为（3．51±2．97）°,未见明显严重的术中及术后并发症。结论Toric人工晶状体可矫正部分外伤性白内障患者的散光,把握合适的手术适应证,可为患者提供更好的预后视力。