Cardiotocographic changes after external cephalic version

Summary. Cardiotocographic tracings before and after 53 attempts at external cephalic version (ECV) in 52 patients were analysed. Hexoprenaline (Ipradol) was used to facilitate ECV in 25 of the 53 attempts. There was a significant decrease in fetal movements and fetal heart rate (FHR) variability and reactivity after external cephalic version; temporary baseline bradycardia occurred in five patients. The most likely explanation for the changes observed is that they represent the fetal response to a period of stress caused by decreased uteroplacental blood flow during the procedure.     

Cardiotocographic changes after external cephalic version

Cardiotocographic tracings before and after 53 attempts at external cephalic version (ECV) in 52 patients were analysed. Hexoprenaline (Ipradol) was used to facilitate ECV in 25 of the 53 attempts. There was a significant decrease in fetal movements and fetal heart rate (FHR) variability and reactivity after external cephalic version; temporary baseline bradycardia occurred in five patients. The most likely explanation for the changes observed is that they represent the fetal response to a period of stress caused by decreased uteroplacental blood flow during the procedure.     

Mode of childbirth and neonatal outcome after external cephalic version: A prospective cohort study

Objectiveto assess the mode of childbirth and adverse neonatal outcomes in women with a breech presentation with or without an external cephalic version attempt, and to compare the mode of childbirth among women with successful ECV to women with a spontaneous cephalic presentation.Designprospective matched cohort study.Setting25 clusters (hospitals and its referring midwifery practices) in the Netherlands. Data of the Netherlands perinatal registry for the matched cohort.Participantssingleton pregnancies from January 2011 to August 2012 with a fetus in breech presentation and a childbirth from 36 weeks gestation onwards. Spontaneous cephalic presentations (selected from national registry 2009 and 2010) were matched in a 2:1 ratio to cephalic presentations after a successful version attempt. Matching criteria were maternal age, parity, gestational age at childbirth and fetal gender. Main outcomes were mode of childbirth and neonatal outcomes.Measurements and findingsof 1613 women eligible for external cephalic version, 1169 (72.5%) received an ECV attempt. The overall caesarean childbirth rate was significantly lower compared to women who did not receive a version attempt (57% versus 87%; RR 0.66 (0.62–0.70)). Women with a cephalic presentation after ECV compared to women with a spontaneous cephalic presentation had a decreased risk for instrumental vaginal childbirth (RR 0.52 (95% CI 0.29–0.94)) and an increased risk of overall caesarean childbirth (RR 1.7 (95%CI 1.2–2.5)).Key conclusionswomen who had a successful ECV are at increased risk for a caesarean childbirth but overall, ECV is an important tool to reduce the caesarean rate.Implication for practiceECV is an important tool to reduce the caesarean section rates.     

Intrapartum external cephalic version

Intrapartum external cephalic version at term was employed in 15 patients with intact membranes and breech presentations; successful version occurred in 11 patients. There were no untoward maternal or fetal outcomes.     

Labor induction just after external cephalic version with epidural analgesia at term

Objective

To analyze the benefits of external cephalic version (ECV) with epidural analgesia at term and labor induction just after the procedure.

Controlled trial of external cephalic version

Summary. A prospective randomized, controlled trial involving 640 singleton breech presentations after 30 weeks gestation was conducted to assess the value of external cephalic version. In 310 patients external cephalic version was attempted; the other 330 patients in whom version was not attempted constituted a control group. There were three perinatal deaths directly attributable to external cephalic version. No significant differences were found between the study and control groups respecting the incidence of vaginal breech delivery, caesarean section rate, perinatal mortality and morbidity. Our results suggest that there is no place for external cephalic version before 36 weeks gestation.     

Intravenous salbutamol for external cephalic version

OBJECTIVE: To evaluate the success of external cephalic version (ECV) using an adjusted bolus dose of intravenous salbutamol compared with no tocolysis. METHODS: An open-label randomized study of 114 women with a term breech fetus randomized to receive either an intravenous bolus dose of 0.1 mg salbutamol with further boluses every 5 minutes, as required, before commencing ECV, or no tocolysis. Primary outcomes were successful ECV and rate of cesarean delivery. RESULTS: Salbutamol tocolysis resulted in a higher rate of successful ECV compared with no tocolysis (70.2% [40/57] vs 36.8% [21/57]; RR 1.9, 95% CI 1.3-2.8; P<0.001). Cesarean delivery rate was lower in the salbutamol group compared with the control group (31.6% [18/57] vs 63.2% [36/57]; RR 0.5, 95% CI 0.3-0.8; P=0.001). Salbutamol dose ranged from 0.1-0.4 mg and outcome was not related to dose. CONCLUSION: Adjusted dose intravenous salbutamol tocolysis prior to ECV increases its success rate and reduces the cesarean delivery rate.     

High incidence of obstetric interventions after successful external cephalic version

Objective To investigate the delivery outcome after successful external cephalic version (ECV).
Design Case–control study.
Setting University teaching hospital.
Population The study group consisted of 279 consecutive singleton deliveries at term over a six-year period, all of which had had successful ECV performed. The control group included 28,447 singleton term deliveries during the same six-year period.
Methods Between group differences were compared with the Mann–Whitney U test or Student's t test where appropriate. Odds ratio and 95% confidence interval (CI) were calculated for categorical variables.
Main outcome measures Incidence of and indications for obstetric interventions.
Results The risk of instrumental delivery and emergency caesarean section was higher in the ECV group (14.3% vs 12.8%; OR 1.4; 95% CI 1.0–2.0, and 23.3% vs 9.4%; OR 3.1; 95% CI 2.3–4.1, respectively). The higher caesarean rate was due to an increase in all major indications, namely, suspected fetal distress, failure to progress in labour and failed induction. The higher incidence of instrumental delivery was mainly due to an increase in prolonged second stage. The odds ratio for operative delivery remained significant after controlling for potential confounding variables. There were also significantly greater frequencies of labour induction (24.0% vs 13.4%; OR 2.0; 95% CI 1.5–2.7) and use of epidural analgesia (20.4% vs 12.4%; OR 1.8; 95% CI 1.4–2.4) by women in the ECV group. The higher induction rate is mainly due to induction for post term, abnormal cardiotocography (CTG) and antepartum haemorrhage (APH) of unknown origin.
Conclusion The incidence of operative delivery and other obstetric interventions are higher in pregnancies after successful ECV. Women undergoing ECV should be informed about this higher risk of interventions.     

Fetomaternal hemorrhage during external cephalic version

OBJECTIVE: To estimate the frequency and volume of fetomaternal hemorrhage during external cephalic version for term breech singleton fetuses and to identify risk factors involved with this complication. METHODS: A prospective observational study was performed including all patients undergoing a trial of external cephalic version for a breech presentation of at least 36 weeks of gestation between 1987 and 2001 in our center. A search for fetal erythrocytes using the standard Kleihauer-Betke test was obtained before and after each external cephalic version. The frequency and volume of fetomaternal hemorrhage were calculated. Putative risk factors for fetomaternal hemorrhage were evaluated by chi(2) test and Mann-Whitney U test. RESULTS: A Kleihauer-Betke test result was available before and after 1,311 trials of external cephalic version. The Kleihauer-Betke test was positive in 67 (5.1%) before the procedure. Of the 1,244 women with a negative Kleihauer-Betke test before external cephalic version, 30 (2.4%) had a positive Kleihauer-Betke test after the procedure. Ten (0.8%) had an estimated fetomaternal hemorrhage greater than 1 mL, and one (0.08%) had an estimated fetomaternal hemorrhage greater than 30 mL. The risk of fetomaternal hemorrhage was not influenced by parity, gestational age, body mass index, number of attempts at version, placental location, or amniotic fluid index. CONCLUSION: The risk of detectable fetomaternal hemorrhage during external cephalic version was 2.4%, with fetomaternal hemorrhage more than 30 mL in less than 0.1% of cases. These data suggest that the performance of a Kleihauer-Betke test is unwarranted in uneventful external cephalic version and that in Rh-negative women, no further Rh immune globulin is necessary other than the routine 300-microgram dose at 28 weeks of gestation and postpartum. LEVEL OF EVIDENCE: II.     

Controlled trial of external cephalic version

A prospective randomized, controlled trial involving 640 singleton breech presentations after 30 weeks gestation was conducted to assess the value of external cephalic version. In 310 patients external cephalic version was attempted; the other 330 patients in whom version was not attempted constituted a control group. There were three perinatal deaths directly attributable to external cephalic version. No significant differences were found between the study and control groups respecting the incidence of vaginal breech delivery, caesarean section rate, perinatal mortality and morbidity. Our results suggest that there is no place for external cephalic version before 36 weeks gestation.     

Antepartum external cephalic version under tocolysis

Reported are 172 patients considered for external cephalic version at gestational age greater than 37 weeks. Their outcome was compared with 40 similar patients in whom external version was not attempted. One hundred fifty-eight patients had attempted version, and success was achieved in 122 (77%). Intrapartum vertex presentation occurred in 12% of the control population and in 77% of the version patients. Cesarean section was performed in 80% of the control patients and in 32% of the version patients. There were no maternal or fetal complications directly attributable to external cephalic version. Antepartum external cephalic version under tocolysis is associated with a high success rate, an acceptably low rate of complications, and a decreased incidence of cesarean section for breech presentation at term.     

Cord blood acid-base status at delivery after successful external cephalic version

BACKGROUND: This study was designed to evaluate whether cord blood acidosis is more likely in infants born after successful external cephalic version. METHODS: This retrospective cohort study included 89 singleton deliveries with successful version performed over a 2-year period. Their cord blood acid-base parameters were compared to 89 pregnancies with spontaneous cephalic presentation (control group). RESULTS: There was no significant difference between the version and control groups in birthweight and Apgar scores. There was no difference between the version and control groups in cord arterial pH (7.26 vs. 7.26), arterial pCO(2) (7.04 vs. 7.09 kPa), arterial pO(2) (2.34 vs. 2.59 kPa), arterial base excess (-5.59 vs. -5.64 mmol/L), venous pH (7.32 vs. 7.33), venous pCO(2) (5.73 vs. 5.63 kPa), venous pO(2) (3.86 vs. 3.84 kPa), or venous base excess (-5.03 vs. -5.12 mmol/L). There was also no significant difference in the number of fetuses with cord arterial pH <7.20 between the two groups. CONCLUSION: Neonates delivered after successful external cephalic version are not more likely to be born with acidosis. Our study provides further support for the safety of external cephalic version for term breech pregnancies.     

Determinants of pain perception after external cephalic version in pregnant women

ObjectiveA considerable proportion of pregnant women with a fetus in breech position refuses external cephalic version (ECV), with fear of pain as important barrier. As a consequence, they are at high risk for caesarean section at term. The current study investigated determinants of pain perception during ECV, with special attention to maternal mental state such as depression and fear of ECV.DesignProspective study of 249 third-trimester pregnant women with breech position with a request for an ECV attempt.SettingDepartment of Obstetrics and Gynaecology in a large teaching hospital in the Netherlands.MethodsPrior to the ECV attempts, obstetric factors were registered, participants fulfilled the Edinburgh Depression Scale (EDS) and reported fear of ECV on a 10-point visual analog scale. Perception of pain intensity was measured with a 10-point visual analog scale, immediately after ECV.FindingsMultivariate linear regression analyses showed success of ECV to be the strongest predictor of pain perception. Furthermore, scores on the depression questionnaire and degree of fear of ECV independently explained pain perception, which was not the case for obstetrical or ECV related factors.ConclusionApart from ECV outcome, psychological factors like depression and fear of ECV were independently related to pain perception of an ECV attempt.Implication for practiceMaternal mood state should be taken into account when offering an ECV attempt to women with a fetus in breech position. Due to the painful experience and the importance of successful outcome, ECV should only be attempted in institutions with experienced practitioners and with careful attention to maternal mood and the way a woman is coping with the ECV attempt.     

Intrapartum cesarean delivery after successful external cephalic version: a meta-analysis

OBJECTIVE: We sought to estimate whether the risk of intrapartum cesarean delivery is higher in pregnancies after successful external cephalic version. DATA SOURCES: We searched the MEDLINE, PubMed, EMBASE, and Cochrane Library databases to identify relevant studies. Abstracts of the American College of Obstetricians and Gynecologists Annual Clinical Meeting and the Society for Maternal-Fetal Medicine Annual Meeting were searched by hand. STUDY SELECTION: Studies published between 1980 and 2002 that provided data allowing us to estimate the cesarean rate in both pregnancies after successful version and spontaneous cephalic-presenting pregnancies were selected. TABULATION, INTEGRATION, AND RESULTS: Relative risks (RRs) and 95% confidence intervals (CIs) between the 2 compared groups were calculated. We used a meta-analysis to assess the heterogeneity of the studies and to combine the results from the included studies. Six eligible studies were identified. The cesarean rate was 27.6% in pregnancies after successful version and 12.5% in cephalic-presenting pregnancies. The combined RR and 95% CI was 2.04 (1.43-2.91). The increased cesarean rate in pregnancies after successful version was accounted for primarily by a higher incidence of emergency cesarean delivery for dystocia and fetal distress; the RR (95% CI) for these 2 events was 2.19 (1.38-3.48) and 2.10 (1.18-3.75), respectively. CONCLUSION: The intrapartum cesarean delivery rate after successful version is 2 times that in pregnancies where there is spontaneous cephalic presentation. Pregnancies after successful version should not be considered the same as a normal pregnancy.