经颅磁刺激治疗脑卒中的Citespace知识图谱可视化分析

背景:经颅磁刺激技术因其无痛、无创、有效及安全性好等优势,在神经心理科、康复医学科及儿科等各个方面得到了广泛应用,但目前尚无针对经颅磁刺激治疗脑卒中领域的可视化分析.目的:客观分析近10年国内外经颅磁刺激治疗脑卒中患者的文献研究,总结该领域近期研究方向及梳理国内外知识结构.方法:基于中国知网和Web of Scienc...     

基于Citespace软骨前体细胞修复软骨相关文献的可视化分析

背景:软骨修复一直是骨科医生面临的巨大挑战,同时也一直是研究的热点,近年来研究发现关节软骨中存在一类具有干细胞特征的软骨前体细胞,为软骨损伤修复研究提供了新的切入点.目的:通过对软骨前体细胞的相关文献进行发文趋势分析、作者合作网络分析、机构合作网络分析,对关键词进行共现分析、聚类分析,探索该领域近20年的发展状况、研究...     

脑卒中后尿失禁10年研究文献的可视化分析

背景:脑卒中后尿失禁发病率逐年上升,治疗手段丰富多样,相关研究不断开展,文献发表也持续涌现,但对于此领域文献的发表情况、核心作者、主要研究机构以及研究焦点等内容未有系统的梳理和总结.目的:利用可视化知识图谱分析软件CiteSpace,针对脑卒中后尿失禁领域近10年的核心期刊文献进行分析,了解其发展脉络、研究热点及未来趋...     

基于Citespace对人工智能在骨创伤研究的可视化分析

背景：人工智能在医疗领域的发展日益迅速,在骨创伤领域的应用研究不断增多。文章旨在通过文献计量学分析,分析近年来人工智能在骨创伤领域中的研究热点,并预测未来的研究趋势。目的：总结人工智能技术在骨创伤领域的应用发展历程、研究现状、热点和未来发展趋势,以期为今后的研究提供新的见解。方法：选择Web of Science核心集数据库中,时间跨度设为自建库至2023年8月,检索人工智能、机器学习、深度学习应用于骨创伤相关的文献420篇。通过人工筛选,导出与文章相关的文献共202篇,采用Citespace软件进行国家、机构、被引期刊和引文分析等的合作和关键词的共现等可视化分析。结果与结论：(1)分析筛选后纳入的202篇文献,总体发文量呈上升趋势,且在未来研究潜力巨大。研究中心性最高和发文量排名第一的国家均为美国。加州大学(美国)是发文量最多的研究机构。(2)人工智能在骨创伤研究中最常用的前5个关键词是深度学习、人工智能、骨密度、机器学习、诊断,中心性最高的关键词为骨密度,关键词数量最多的为深度学习。(3)共被引频次前10位的参考文献分别从多个方面介绍了人工智能技术应用于骨创伤领域诊断的可行性研究,...     

有氧运动对抑郁症患者认知功能干预效果的meta分析

目的:系统评价有氧运动对抑郁症患者认知功能的干预效果。方法:检索PubMed、Web of Science、EBSCO host、Cochrane Library、中国知网、万方数据库,收集从建库至2021年7月公开发表的有氧运动干预抑郁症患者认知功能的随机对照试验,采用Stata软件进行数据分析。结果:共纳入12项随机对照试验,985例抑郁症患者。Meta分析结果显示,有氧运动可改善抑郁症患者的视觉学习与记忆(SMD=0.30,95%CI:0.15～0.45,P<0.001)、执行功能(SMD=-0.37,95%CI:-0.66～-0.07,P<0.05),对信息处理速度、工作记忆、注意/警觉性、言语学习与记忆以及推理与问题解决改善效果不明显(均P>0.05);停止有氧运动干预后,试验组视觉学习与记忆评分与对照组差异无统计学意义(P>0.05);亚组分析结果显示,中、高强度并持续12～16周的有氧运动对视觉学习与记忆改善效果最佳(SMD=0.24、0.34、0.32,95%CI:0.01～0.48、0.14～0.54、0.15～0.49),中等强度并持续4～8...     

基于知识图谱的骨缺损治疗可视化分析

背景:骨缺损作为运动系统的常见疾病,采用有效手段对其进行治疗具有十分重要的意义,但目前国内尚缺少使用文献计量学对骨缺损治疗进行研究的文献综述.目的:针对近10年来发表的骨缺损治疗文献进行文献计量学分析,探究该领域的研究现状、研究热点和研究趋势,并为其未来发展提供意见与建议.方法:以Web of Science Core...     

可视化分析关节软骨修复领域的研究热点与趋势

背景:由于关节软骨的自我修复能力非常有限,自然退变或创伤等引起的关节软骨缺损往往无法自行修复,进而引发或加重骨关节炎,甚至导致严重残疾,因此关节软骨损伤的修复治疗已成为临床上亟待解决的问题。目的:运用文献计量学方法分析归纳关节软骨修复领域的研究热点及发展趋势。方法:从Web of Science核心合集中检索2000-2023年关节软骨修复的相关文献,运用VOSviewer、Citespeace和Bibliometrix R-package进行文献计量与可视化分析。结果与结论:关节软骨修复领域年度发文量总体呈现上升趋势,美国、中国、德国是发文量前三的国家,研究机构集中于大学和医院,哈佛大学、纽约特种外科医院、上海交通大学是发文量前三的机构。《AMERICAN JOURNAL OF SPORTS MEDICINE》是出版该领域研究文献最多的期刊,《BIOMATERIALS》则是该领域被引次数最多的期刊。“Injectable hydrogels for cartilage and bone tissue engineering”是近10年间发表的被引次数最多的文献,发文量最多的作者是Madry Henning,该领域的活跃作者相互之间形成了多个结构稳定的研究团队,不同团队间的合作有待进一步加强。关节内注射、胫骨高位截骨、水凝胶、药物递送、炎症、软骨再生及支架是当前该领域研究的热点内容,3D打印技术、生物墨水、蚕丝蛋白、可注射水凝胶、外泌体等在关节软骨修复中的应用可能是该领域研究前沿。整合各种创新技术和方法以实现更有效、持久且功能性的关节软骨再生和修复,并通过开展更多高质量的临床研究以促进相关技术和方法的临床转化可能是该领域未来的研究趋势。     

眼动技术对自闭症患者认知行为学研究的可视化分析

背景:眼动技术因其能客观及时且无创地反映自闭症患者的眼球运动和注意特征,较好地弥补了传统测量方法缺乏的客观性,得到了中国学者的关注,目前尚无针对眼动技术研究自闭症患者的可视化分析.目的:利用文献计量学方法对自闭症眼动研究的相关中英文文献进行可视化分析,了解中国和国际上该领域的研究概况、热点及趋势.方法:检索Web of...     

运动与认知功能改善的研究进展

认知老化导致的认知功能衰退是老龄化过程中的全球性的公共健康问题,对于降低认知老化发生和发展的速度,目前尚无明确、统一的治疗原则可循。由神经营养因子减少所致的认知功能衰退逐渐引起人们的重视,运动作为有效的、低成本的干预方式,在认知功能衰退的早期,从一定程度上起到改善和延缓的作用。探讨有氧运动通过神经营养因子和生长因子对认知功能衰退改善作用的内在机制,从而对延缓认知功能衰退的运动干预方案的制定提供参考。     

人工智能在脊柱畸形领域研究热点的可视化分析

背景：随着人工智能技术在治疗脊柱畸形领域的不断完善与进步,已有大量的研究投入到该领域当中,但主要研究现状、热点和发展趋势尚不明确。目的：采用文献计量学的方法可视化分析人工智能在脊柱畸形领域的相关文献,明确该领域的研究热点和不足,为今后研究工作研究提供参考。方法：在Web of Science核心集数据库检索建库至2023年收录的人工智能在脊柱畸形领域相关文献,通过Citespace 5.6.R5和VOSviewer 1.6.19软件对文献数据进行可视化分析。结果与结论：(1)共纳入文献165篇,此领域年发文量呈波动上升趋势,发文量最多的作者是Lafage V,发文量最多的国家是中国。(2)关键词分析结果显示,青少年早发性脊柱侧弯、深度学习、分类、精度和机器人是该研究领域的主要高频关键词。(3)文献共被引和高被引文献深度分析结果显示,人工智能在脊柱畸形领域有3大热点,包括利用U型架构(深度学习卷积神经网络的一种成熟模式)来自动测量影像学参数(Cobb角、棘旁肌准确分割等)、多视图相关网络架构(即脊柱曲度评估框架)及机器人引导脊柱手术。(4)在人工智能治疗脊柱畸形领域,基因组学等机制研究十...     

功能性近红外光谱技术的10年发展:CiteSpace知识图谱可视化分析

背景:功能性近红外光谱技术是一种新兴的无创脑功能活动监测手段,对于脑成像显示出独特的优势,属于脑科学领域中新的研究热点.目的:以CiteSpace知识图谱为基础,对国际上功能性近红外光谱技术相关研究文献进行计量学分析、共现分析、共被引分析和聚类分析,探索功能性近红外光谱技术近10年研究概况和目前研究热点,以期为未来研究...     

Menstrual symptoms: A social cognition analysis

Research on menstrual-related cyclicity often reflects assumptions concerning the generality, severity, and physiological basis of symptoms associated with the menstrual cycle. According to arguments presented in recent articles, these assumptions are not fully justified by the empirical data. In addition, there is evidence that symptom associations may be viewed a reflecting, in part, a set of beliefs. In the present article evidence is reviewed which suggests that symptom associations may originate and be maintained by means of biases in the processing of information about cyclicity. Specifically, the origins of biased beliefs may arise from the connotative meaning of, the salience of, and selectivity in processing the information forming the association. In addition, mechanisms which have been tribute to the maintenance of biased perceptions, once associations have been formed, include distortion, autonomy, and category accessibility of the evidence.     

Self-reported cognition in older adults with insomnia: Associations with sleep and domain specific cognition

Poor subjective evaluation of cognition and sleep are associated with cognitive decline in older adults. Relationships among self-reported cognition, sleep, and cognitive domains remain unclear. We evaluated the interactive associations of objective cognition and subjective sleep with self-reported cognition in older adults with insomnia. Fifty-one older adults (M_age = 69.19, SD = 7.95) with insomnia completed 14 days of self-reported cognition ratings (0-very poor, 100-very good), sleep (total sleep time (TST), sleep onset latency (SOL), wake after sleep onset (WASO), sleep efficiency), and daily cognitive tasks: Letter series (reasoning), word list delayed recall (verbal memory), Symbol Digit Modalities Test (SDMT) (attention/processing speed), and number copy (processing speed). Multiple regressions for each cognitive task determined whether average objective cognition or sleep were independently/interactively associated with average self-reported cognition, controlling for age, education, and depression. The interaction between SDMT performance and TST was associated with self-reported cognition. Specifically, the relationship between scores and self-reported cognition was congruent in those with the shortest TST. Similarly, the interactions between SDMT and WASO, as well as sleep efficiency, were associated with self-reported. Specifically, the relationship between scores and self-reported cognition was congruent in those with longest and average WASO, as well as shortest and average sleep efficiency. The findings suggest, in an older adult population with insomnia, a congruent association exists between attention/processing speed and self-reported cognition in those with worse subjective sleep (shorter TST, longer WASO, and lower SE). Insomnia symptoms should be taken into consideration when examining the relationship between objective cognition and self-reported cognition.     

骨盆整复手法研究现状与发展趋势的文献计量学与可视化分析

背景:有关骨盆整复类手法的相关文献缺乏客观、系统的数据统计分析,不利于学者快捷、直观地了解相关研究动态.目的:检索中英文数据库有关骨盆整复类手法的所有研究资料,分析探讨目前骨盆整复类手法的区域特色、研究现状和发展趋势.方法:检索中国知网和Web of Science数据库建库至2020-03-26期间公开发表的关于骨盆...     

Docosahexaenoic acid dietary supplementation enhances the effects of exercise on synaptic plasticity and cognition

Omega-3 fatty acids (i.e. docosahexaenoic acid; DHA), similar to exercise, improve cognitive function, promote neuroplasticity, and protect against neurological lesion. In this study, we investigated a possible synergistic action between DHA dietary supplementation and voluntary exercise on modulating synaptic plasticity and cognition. Rats received DHA dietary supplementation (1.25% DHA) with or without voluntary exercise for 12 days. We found that the DHA-enriched diet significantly increased spatial learning ability, and these effects were enhanced by exercise. The DHA-enriched diet increased levels of pro-brain-derived neurotrophic factor (BDNF) and mature BDNF, whereas the additional application of exercise boosted the levels of both. Furthermore, the levels of the activated forms of CREB and synapsin I were incremented by the DHA-enriched diet with greater elevation by the concurrent application of exercise. While the DHA diet reduced hippocampal oxidized protein levels, a combination of a DHA diet and exercise resulted in a greater reduction rate. The levels of activated forms of hippocampal Akt and CaMKII were increased by the DHA-enriched diet, and with even greater elevation by a combination of diet and exercise. Akt and CaMKII signaling are crucial step by which BDNF exerts its action on synaptic plasticity and learning and memory. These results indicate that the DHA diet enhanced the effects of exercise on cognition and BDNF-related synaptic plasticity, a capacity that may be used to promote mental health and reduce risk of neurological disorders.     

Translational cognition for decision support in critical care environments: a review

The dynamic and distributed work environment in critical care requires a high level of collaboration among clinical team members and a sophisticated task coordination system to deliver safe, timely and effective care. A complex cognitive system underlies the decision-making process in such cooperative workplaces. This methodological review paper addresses the issues of translating cognitive research to clinical practice with a specific focus on decision-making in critical care, and the role of information and communication technology to aid in such decisions. Examples are drawn from studies of critical care in our own research laboratories. Critical care, in this paper, includes both intensive (inpatient) and emergency (outpatient) care. We define translational cognition as the research on basic and applied cognitive issues that contribute to our understanding of how information is stored, retrieved and used for problem-solving and decision-making. The methods and findings are discussed in the context of constraints on decision-making in real-world complex environments and implications for supporting the design and evaluation of decision support tools for critical care health providers.     

Factors influencing self-assessment of cognition and functioning in bipolar disorder: a preliminary study

Introduction. Self-assessment deficits are common in schizophrenia and span multiple aspects of functioning, including awareness of symptoms, and the ability to assess objective levels of cognitive deficits and everyday functioning. Whereas impaired awareness of illness in bipolar disorder during symptomatic periods is well understood, awareness of disability and cognitive deficits has been less well studied.

Methods. In this pilot study, 30 patients with a lifetime history of bipolar I disorder and current bipolar depression completed performance-based tests of cognition and functional capacity and self-reported their opinions of their cognitive abilities, everyday functioning and symptoms. High contact clinicians also provided impressions of the patients’ cognitive performance and everyday functioning.

Results. Clinician impressions of cognition and everyday functioning were correlated with the results of the performance-based assessments, whereas the patient self-reports of cognition and functioning were uncorrelated both with their own performance and with the clinician impressions. However, severity of depressive symptoms was correlated with self-reports of functioning in cognitive and functional domains, but not with either performance-based data or clinician impressions of cognition or functioning.

Conclusions. Depression appears to be a factor affecting self-assessment in bipolar disorder and reports of cognition and functioning were minimally related to objective information and clinician impressions. Symptoms of mania were minimal and not correlated with performance-based assessments or clinician impressions.     

Web of Science数据库来源心肌细胞直接重编程研究热点:文献计量学及可视化分析

背景:心肌细胞直接重编程技术是近年再生医学领域的研究热点,可能成为心脏疾病治疗的新途径,有着广阔的应用前景和发展方向.目的:通过对心肌细胞直接重编程文献进行CiteSpace知识图谱绘制及可视化计量分析,梳理该领域的研究进展、研究热点以及发展趋势,为相关领域研究者提供借鉴与参考.方法:在Web of Science核心...     

The deep biology of cognition: Moving toward a comprehensive neurodevelopmental model of Turner syndrome

Individuals with Turner syndrome (TS) often exhibit specific deficits in visual–spatial functions, arithmetical abilities, social cognition, and executive functions with preserved general intelligence and preserved or enhanced verbal skills. This unique pattern of cognitive strengths and weaknesses is accompanied by a well‐described neuroanatomical phenotype characterized by decreased gray matter volumes in premotor, somatosensory, and parietal‐occipital cortex, and increased volumes of the amygdala and orbitofrontal cortex. Why the absence of the second sex chromosome should produce these effects remains poorly understood. In this article, we propose that the TS research community leverage recent advances in neuroimaging, large‐scale data‐rich biology (omics), and patient‐powered research registries to build a comprehensive neurodevelopmental model of TS.     

Illness cognition and behavior: An experimental approach

The study of illness cognition and behavior has relied primarily on nonexperimental research designs. In this paper we review the results of a program of experimental investigations of psychological reactions to health threats. Most of the studies employ a new experimental paradigm developed to study illness cognition and behavior in the laboratory. The paradigm has been used in several experiments to examine the cognitive and motivational processes underlying reactions to medical test results. A converging series of studies has shown that denial, manifested in a variety of ways, is a common initial reaction to threatening information. In addition, the studies demonstrate that the perceived prevalence of a health disorder is an important determinant of its perceived seriousness. The insights gained from these studies illustrate the complementary roles of basic experimental research and more naturalistic observational research in the formulation of comprehensive theories of health and illness behavior.