Method to impact in vivo rabbit femoral cartilage with blows of quantifiable stress

The purpose of this study was to develop a technique by which a known stress could be applied uniformly across the femoral cartilage of a rabbit as a model for the development of post-traumatic arthritis. A system to impact the cartilage was designed that consisted of an apparatus to deliver a blow of quantifiable force, a method to apply the stress uniformly over the impact area, and a way to accurately measure the impact area. The knee joints of cadaveric New Zealand White rabbits were surgically exposed with the knee flexed so that the distal femoral articular surface was perpendicular to an impactor. With the knee fixed in, position, a cup containing polymethylmethacrylate bone cement was applied to create an exact contour of the femoral surface, and the cement was allowed to cure. The form was then rested on the rabbit knee, and a drop tower, released a weight of known mass from a known height onto an impactor (instrumented with strain gauges to measure the compressive force) that was attached to the cup. The area of the impacted surface was determined and, with the measured force, was used to calculate an accurate estimate of the impact stress. This method can be performed under sterile conditions, and therefore it is well suited for survival experiments in which the long-term effects of impact to cartilage will be studied.     

Intraartikuläre Punktionen und Injektionen

Joint punctures and injections are a widely used approach to obtain a differential diagnostic assessment for the formation of a treatment concept for recurrent joint effusions, to exclude a periprosthetic infection in painful and loosened endoprostheses before a planned revision, to assign the origin of pain symptoms to a specific joint or to provide a treatment for arthritis of any kind. In all medical fields the standardization of processes has progressed. Therefore, for joint punctures there are standards relating to the implementation and hygiene of intra-articular punctures or injections in order to prevent the occurrence of complications, such as joint infections.     

Intraductal spread by metastatic islet cell tumor (well-differentiated pancreatic endocrine neoplasm) involving the breast of a child, mimicking a primary mammary carcinoma

Metastases to the breast are rare, accounting for an estimated 1% to 2% of malignant breast neoplasms. The key histopathologic features supporting a metastasis to the breast have been stated to be the absence of elastosis, presence of a pushing border (circumscribed lesion), multiple satellite foci, lymphatic emboli, and, most importantly, the absence of an in situ carcinoma component. We report a unique case of a pancreatic islet cell tumor metastatic to the breast of an 18-year-old girl. Clinically, the patient was thought to have a mammary primary because on her initial biopsy, the metastasis grew within mammary ducts and colonized a complex sclerosing lesion, simulating an in situ component. However, review of slides from the prior pancreatic neoplasm, review of slides from the subsequent mastectomy, and use of immunohistochemistry allowed recognition of the lesion as a metastasis, which proved to be the first clinical manifestation of a systemic relapse. To our knowledge, this is the second case of islet cell tumor reported to metastasize to the breast, and the first report of a metastasis proven to have grown within existing ducts of the breast by immunohistochemistry.     

Conversion of a fused hip to total hip arthroplasty

BACKGROUND: Arthrodesis of the hip remains a viable treatment for severe unilateral arthritis after traumatic injury or infection in a young but otherwise healthy individual. The goal of the present study was to review the long-term clinical and radiographic results after conversion of a fused hip to a total hip arthroplasty and to identify the risk factors that would lead to a higher rate of failure. METHODS: We performed a retrospective review of the charts and radiographs of 187 patients (208 hips) who had conversion of a fused hip to a total hip arthroplasty. The mean duration of follow-up after the conversion to total hip arthroplasty was 9.2 years (range, two to twenty-six years). RESULTS: The mean age at time of the arthroplasty was fifty-one years. The mean time-interval between the arthrodesis and the conversion to a total hip arthroplasty was twenty-seven years. According to the information in the charts, at a mean duration of follow-up of 9.2 years after the total hip arthroplasty, 79% of hips were either pain-free or had minimal pain, 83% had good-to-excellent function, and 79% had good-to-excellent range of motion. Complications, which included fifteen nerve palsies, occurred in twenty-four hips. Twenty-eight hips had heterotopic ossification, but it was not associated with a recurrence of ankylosis or a marked reduction of motion. Revision arthroplasty was performed in twelve hips. The probability of survival of the implant was 96.1% (95% confidence interval, 91.5% to 98.2%) at ten years, 89.9% (95% confidence interval, 85.3% to 96.1%) at fifteen years, and 72.8% (95% confidence interval, 36% to 90.6%) at twenty-six years. CONCLUSIONS: Conversion of a fused hip to a total hip arthroplasty has a favorable outcome. However, the technically demanding nature of the procedure should not be underestimated. Patients should be cautioned with regard to the possibility of a higher rate of complications than that seen with primary total hip arthroplasty.     

A Novel Digital Tourniquet Using a Sterile Glove and Hemostat

Background. Surgery of the digit is facilitated with adequate hemostasis for visualization of the operative field. Several types of tourniquets have been used for this purpose, including glove fingers, Penrose drains, Marmed digital tourniquets, and standard pneumatic tourniquets.
Objective. To present a novel method to achieve hemostasis during surgery of the digit.
Materials. A slightly oversized sterile glove, a hemostat, and a pair of scissors.
Conclusion. We present a novel method to achieve hemostasis using a sterile glove and a hemostat, that allows the surgeon to methodically titrate the amount of compression necessary to attain a bloodless field while minimizing the risks of excessive pressures.
Surgery of the digit is facilitated with adequate hemostasis for visualization of the operative field. Several types of tourniquets have been used for this purpose, including glove fingers, Penrose drains, Marmed digital tourniquets, and standard pneumatic tourniquets. We present a novel method to achieve hemostasis using a sterile glove and a hemostat that allows the surgeon to methodically titrate the amount of compression necessary to attain a bloodless field while minimizing the risks of excessive pressures.     

Selection of the bronchial tube for one-lung anesthesia by multidetector-row computed tomography (MD CT) evaluation

One-lung anesthesia is a method of anesthesia performed by inserting the tip of a bronchial tube into either the right main bronchus or the left main bronchus. The right bronchial tube is a special structure. Since the distance of the carina to the right upper lobe bronchus is short, a side hole is made to prevent blockading of the right upper lobe bronchus, and the cuff is attached aslant to it. When inserting a bronchial tube into the right main bronchus, care is required to prevent the occurrence of atelectasis though a gap in the bronchial tube. We evaluated the structure of a trachea and a bronchus using the multidetector-row computed tomography (MD CT), and tried to select the right bronchial tube most suitable for each structure. There are individual differences in the structure of a trachea and a bronchus. By creating a 3-dimensional image of a trachea and a bronchus, the structure could be easily grasped, and therefore selection of the most appropriate bronchial tube according to the structure was possible.     

Prototype of a system for electric conduction at contact with laparoscopic tools

The authors present their prototype of a system for electric conduction at contact with laparoscopic tools, devised, designed and produced by them at the Politecnico di Torino, Department of Mechanical Engineering. The system consists of a two sided plate, one side is a non conducting adhesive surface to stick to the surgical glove and the other side is a subtle flexible shell of a conductor. The Authors used the instrument with surgical tools with a metallic handle, during three cholecystectomies. Nowadays all standard laparoscopic tools have the chance and the need to be electrified. Now the way commonly used to electrify a laparoscopic tool is using a wire plugged to a fixed conducting point of the instrument. This prototype has been devised and produced to avoid some discomforts met during the numerous manoeuvres of connecting and disconnecting the wire at the time of a surgical intervention. This device permits the direct transfer (by contact) of electric energy from the wire to surgical tools. The advantage is to be more rapid in changing surgical tools obtaining, immediately an electrified instrument in your hand.     

Communication between functional and denervated muscles using radiofrequency.

OBJECTIVE: This article focuses on establishing communication between a functional muscle and a denervated muscle using a radiofrequency communications link. The ultimate objective of the project is to restore the eye blink in patients with facial nerve paralysis. STUDY DESIGN AND SETTING: Two sets of experiments were conducted using the gastrocnemius leg muscles of Sprague-Dawley rats. In the initial tests, varying magnitudes of voltages ranging from 0.85 to 2.5 V were applied directly to a denervated muscle to determine the voltage required to produce visible contraction. The second set of experiments was then conducted to determine the voltage output from an in vivo muscle contraction that could be sensed and used to coordinate a signal for actuation of a muscle in a separate limb. After designing the appropriate external communication circuitry, a third experiment was performed to verify that a signal between a functional and a denervated muscle can be generated and used as a stimulus. RESULTS: Voltages below 2 V at a 10-millisecond pulse width elicited a gentle, controlled contraction of the denervated muscle in vivo. It was also observed that with longer pulse widths, higher stimulation voltages were required to produce sufficient contractions. CONCLUSION: It is possible to detect contraction of a muscle, use this to generate a signal to an external base station, and subsequently cause a separate, denervated muscle to contract in response to the signal. SIGNIFICANCE: This demonstration in vivo of a signaling system for pacing of electrical stimulation of 1 muscle to spontaneous contraction of another, separate muscle, using radiofrequency communication without direct connection, may be used in numerous ways to overcome nerve damage.     

Oral styletted intubation under video control in a patient with a large mobile glottic tumour and a difficult airway

PURPOSE: With fibreoptic intubation, advancement of the endotracheal tube (ETT) through the glottis is blind. Thus, in patients with a laryngeal tumour, there is a potential for damage to the tumour. Previously, we proposed the use of a fibreoptic bronchoscope (FOB)-video camera system to permit visualization of tube passage. We used this technique successfully in a patient with a known difficult airway and a large glottic tumour. CLINICAL FEATURES: A 61-yr-old man with a known history of difficult laryngoscopic intubation underwent laryngeal microsurgery for recurrence of a glottic tumour. As preoperative indirect laryngoscopy revealed a large, mobile, and pedunculated glottic lesion obstructing the glottic opening, we planned a conventional awake fibreoptic intubation. Endoscopy showed that the tumour partially obstructed the glottis and the space between the tumour and the glottic opening was very narrow. To avoid damage to the tumour, we changed to an alternative fibreoptic intubation technique. The FOB attached to a video camera was passed nasally and a jaw thrust manoeuver was applied, providing an excellent view of the larynx. An anesthesiologist inserted the ETT with a curved stylet orally, and carefully advanced the tube tip into the space between the tumour and the glottic opening under video control. Absence of damage to the tumour and passage of the tube between the cords were confirmed visually. CONCLUSION: This alternative intubation technique, providing a view of the tube passage into the glottis, was a reasonable method to avoid potential damage to the glottic tumour by blind tube passage during conventional fibreoptic intubation.     

Management of duodenal-pancreatic endocrine tumors

Endocrine tumors of pancreas and duodenum have a common diagnostic and therapeutic approach. Surgery has a key role to play in the management of patients with such tumors. According to a particular patient, this role is to get under control a secretory syndrome which is refractory to medical therapy, to eradicate a malignant or a premalignant tumor, to produce cytoreduction by debulking, or to palliate complications due to massive regional extension of a malignant tumor.     

Reliability of different grading systems used in evaluating surgical students

Inter-rater agreement in assigning grades using five different grading systems was determined. The performance of 16 students in a surgery clerkship was rated by 21 faculty raters using a pass-fail grading system, a pass-fail-honors system, a letter grade system, a number grade scale from 1 to 10, and a number grade scale from 1 to 100. Inter-rater agreement coefficients were used to assess relative and absolute reliabilities, respectively. Both the letter grade and 1 to 10 number grade systems provided good discrimination, had high to moderate reliability, and required only five raters to achieve a mean rating with the commonly recommended reliability of 0.80. Using the letter grade system, however, a majority of raters agreed on a specific grade assignment for 14 of 16 students, in contrast to the 1 to 10 scale, for which this was true for only 4 of 16 students. The results of this reliability study favor the use of a letter grading system.     

Tibial insert micromotion of various total knee arthroplasty devices

The objective of this study was to develop a novel method to quantify rotational micromotion of modular tibial components that incorporates physiologic loading conditions, a physiologic test environment, and constraint characteristics of the articulating surface. The methodology is reviewed and data are presented on four total knee designs. Results showed the design with a rotational stabilizing island to demonstrate the most capability in resisting rotational micromotion for a given reacted torque, followed by a full peripheral capture device, then a partial peripheral capture device, and then a full peripheral capture device with a posterior lipped edge. Under walking and stair-climbing loads, the full peripheral capture device imparts more torque to the insert than the other designs due to the higher constraint of its articulating surface and thus experiences the most micromotion. The rotational stabilizing island device reveals the least amount of motion, due to a combination of its locking mechanism and a less constrained articular surface.     

Digital videoproctoscopy: a new diagnostic test in proctology

The proctological examination is usually simple, it can be done even without specific preparation. It is completed by proctoscopy, enabling the surgeon to confirm a clinical suspicion and make a differential diagnosis. Proctoscopy, however, may present a number of difficulties: the embarrassing position (both in the Sims and in the genupectural position; the operator is very close to the perineum of the patient); it is not possible to provide visual evidence of the pathology; there are no data archives; no comparison of two examinations can be made after a certain period of time (e.g. to test the validity of the therapy adopted). For these reasons patients are often invited to undergo a video-colonoscopy, which also presents limitations such as low patient compliance, difficult medium- and short-term repetition; ineffective discrimination of anal canal diseases, and, last but not least, the cost, which is substantially higher than that of anoscopy. The Author presents the results of experimentation with digital Videoproctoscopye (Proctomedia s.r.l., Rome, Italy), performed with the aid of a bar on which is situated a separate-head digital camera, a solid light source with an optical fibre guide, and an insufflation channel. The top of the bar can be attached with a bayonet coupling to a disposable rigid proctoscope. The tool is connected to a high-resolution LCD monitor and to a high-definition digital tape with an ethernet card, allowing the surgeon to record images on an SD card. Three hundred and seventy-six digital videoproctoscopies were carried out, enabling the author to make a correct diagnosis of the anal, perianal and rectal pathologies.     

Discharging to a nursing home: not a terminal event--a follow-up study of senior motor vehicle crash patients

Discharge to a nursing home (NH) because of chronic debilitating diseases or old age is generally a terminal event. The purpose of this study was to evaluate the NH outcome of senior citizens injured in motor vehicle crashes (MVC) discharged to a NH. From 2000 through 2004, 157 patients 75 years and older were admitted to the hospital for MVC. Of these, 32 patients were discharged to a NH, and these patients or their proxies were interviewed by telephone in June 2005 to request information as to driving status before and after the MVC, feeding, expression, and locomotion status, and/or date of death. After discharged from the NH, 72 per cent (23/32) of the patients lived at home, 52.2 per cent (12/23) among the drivers returned to drive, and those with functional impairments (excluding the five NH deaths and four still remaining in a NH) at the time of hospital discharge had 100 per cent or partial improvement in three functional independent measures at the time of the interview: 5 cases in feeding, 2 in expression, and 20 in locomotion. Eleven of the 20 individuals dependent or partially dependent in locomotion status were fully independent. The majority of the senior patients discharged to a NH after a MVC returned to a normal life by going back home, driving again, and regaining functional activities after NH discharge. Discharge to a NH for elderly MVC trauma patients may be regarded as a stepping-stone to independent living rather than a final resting place.     

Now you see it,now you don’t: A discourse view of disability and multidisciplinarity

Disability is increasingly salient as a word and increasingly heterogeneous as a category. Multiple interest groups and professions define disability in different ways, making it impossible to achieve a unitary theoretical definition or singular model-explanation of disability as a phenomenon. It is in the interest both of disability scholars and disabled people to acknowledge the multiple understandings of disability, and to appropriate ways of thinking and talking about disability that are often seen as antithetical to a progressive understanding of disability. This particularly applies to medical language, which may be used to deepen our understanding of disability without the traditionally attendant problem of medicalization. Such a project requires a deeper engagement with the particularities of medical language, but also with chronic illness, which is sometimes dichotomized from impairment on spurious grounds. Disability studies should acknowledge the utility of medical language as a tool for people with chronic illnesses as well as impairments to conceptualize their embodied experience, and strive for ways to situate medical language within a sociopolitically progressive understanding of chronic illness, impairment, and disability.     

Comparison of stainless steel and composite plates in the healing of diaphyseal osteotomies of the dog radius: report on a short term study.

The rigid fixation of fractures is generally accepted as the best method to achieve union when open treatment of a fracture is undertaken. This has led to the development of plates that have a greater overall dimension and stiffness compared to earlier plate models, as exemplified by the Lane or Eggers type of plate. In our experience the more rigid plate generally leads to satisfactory union, but also carries with it the risk of refracture, either through a screw hole or across the original fracture after plate removal. Experiments by Uhtoff and Dubuc on experimental animals showed that plate induced osteopenia existed when a rigid plate was applied to an intact or osteomized canine femur. These results provide a possible explanation for the occurrence of late fracture. The study to be described is based on the hypothesis that a rigid plate applied to bone induced localized immobilization osteopenia, which ultimately weakens the bone and leads to the development of late fracture. The study was designed to compare a plate made of stainless steel, which exhibited mechanical stiffness comparable to that of devices presently in use, with a plate made of a composite material, which exhibited decreased stiffness by nearly one order of magnitude. It had been demonstrated by engineering analysis that the less stiff plate would allow the bone to experience normal loading, and it was thought that this loading would modulate the rate and pattern of bone remodeling, thereby resulting in bone of greater strength and size as compared to a more rigidly plated bone.     

Upper eyelid reconstruction: a short report of an eyelid defect following a thermal burn

While the principles of eyelid reconstruction are well-established, achieving good functional and aesthetic reconstruction remains challenging. This communication presents a technique that we used on a young patient with an eyelid defect following a thermal burn. The patient was operated on to reconstruct the entire upper eyelid using, as a posterior lamella, a mucochondrial autologous graft taken from the ala of the nose as a tarsus and conjunctiva substitutes that were sutured to the Elevator palpebrae superioris aponeurosis and muscle. On the other hand, to reconstruct the anterior lamella, which consists of skin and muscle, the surgeons used a myocutaneous temporal flap taken from the region immediately lateral to the external canthus of the palpebral region, and which, after being isolated following a drawing of the upper eyelid to be reconstructed, was rotated and then sutured to the posterior lamella using the orbicularis oculi muscle as a pedicle.     

The stereotactic volumetric information: its role in two-step resection of brainstem and thalamic giant tumor. Report of three cases and technical note

BACKGROUND: A compact intracerebral tumoral lesion is usually considered to be completely resectable. Nevertheless, radical resection of a huge lesion located in a critical area may damage the surrounding compressed brain tissue. In cases with a good prognosis, a two-step removal appears to be a safer strategy. METHODS: In three cases, two with huge brain stem lesions and one with a thalamic lesion, a two-step volumetric stereotactic resection was planned. This strategy allowed us to evaluate the amount of tumor to be removed during the first procedure and to have, during the second operation, an exact definition of the reduced mass with regard to the scar tissue and postoperative adhesions. Furthermore, we avoided significant shifting of the cerebral structures during both procedures. RESULTS: There was a very good final recovery in the cases with brain stem lesions and a minimal deficit in the patient with the thalamic lesion. The patient with a mesencephalic lesion remained comatose for almost 2 days after the first procedure, confirming our fears about too radical a one-step resection. CONCLUSIONS: We think that by using current techniques, it is possible to remove a well circumscribed lesion regardless of its position. This is probably easier with giant lesions where a safe trajectory can be planned. In these cases, with lesions located in very critical areas but with a good prognosis, a two-step resection appears to be a good option.     

A case of ureterovesical malacoplakia that manifested hydronephrosis

A 70-year-old woman visited a nearby physician with a chief complaint of fever and was admitted to a hospital with a diagnosis of acute pyelonephritis. After discharge, pyuria persisted and examination revealed an intravesical solid tumor. The patient was referred to this department for close examination and treatment. The right kidney was hydronephrotic. The intravesical tumor that was resected was solid yellowish-white and ranged from the neck of the uterus to both ureteral orifices. In addition, a grain-sized tumoral lesion, was found in the lower part of the ureter and was also resected. There was sclerotic thickening localized to the right intramural ureter, which had a slightly edematous interior. This was considered to be the cause of the hydronephrosis and a ureteral stent was put in place. Pathological diagnosis was given as malacoplakia. With this case, placement of a ureteral stent was chosen based on the findings of a minimal ureteral lesion, a narrow area of scarring in the intramural ureter as a probable cause of hydronephrosis, and a judgement of mild obstruction. A stent is less invasive for patients, but consideration should be given to urinary infection due to long-term placement recurrence of malacoplakia due to the increased risk of infection, and trouble with periodical exchanging of catheters due to aggravated scarring. Absence of pyuria or signs of recurrence after seven months' placement suggests that use of the stent was the best method.     

Cleft of the lower lip, mandible and sternum. A case report and review of the literature

The Authors report a case of cleft interesting the lower lip and mandible with a sternal cleft. This association is exceptional, it was described in three world cases to this day. At this occasion, a review of the literature is realized, in particular concerning the associated malformatives anomalies and the therapeutic behaviour. It seems to us indispensable to realize an early reconstruction, specially bone correction, and to collaborate with a multidisciplinary team to obtain a good result and a better social incorporation of the child.