Beyond冷光美白临床疗效的观察

目的观察采用Beyond冷光美白法对临床色素牙齿脱色的美白效果。方法临床选取一定时间段内适合冷光关白的患者46例,按照生理性黄牙、四环素牙、氟斑牙分为三组,采用Beyond冷光美白后观察牙齿颜色的变化,比较有效率,并对满意度进行了调查。结果对被分为生理性黄牙、四环素牙、氟斑牙三组患者治疗后的牙齿颜色等级与治疗前均有不同程度提升,患者对治疗效果比较满意。结论冷光美白法是一种安全、快捷、有效的方法,值得临床推广。     

Beyond冷光美白牙齿的疗效及安全性评价

目的 评价Beyond 冷光美白术漂白着色牙-黄牙(含先天黄牙、增龄性变色牙)和四环素牙的疗效及安全性.方法 用Beyond冷光美白仪及配套的冷光美白剂对31例(496颗)黄牙、34例(544颗)四环素牙进行漂白.以第二双尖牙为空白对照.用VITA比色板作脱色前后比较,分析脱色效果;观察术中、术后患者敏感情况,术中牙龈损伤情况.结果 黄牙组平均提高6.32个色阶,有效率100.0%.四环素牙平均提高5.37个色阶,有效率98.5%.术中约84.6%的患者有程度不等的牙齿敏感症状, 术后约89.2%的患者有不同程度牙齿敏感症状,约13.8%的患者出现牙髓刺激症状,24～72 h可自动消除.约10.5%的患牙术中出现牙龈灼伤.结论 Beyond冷光美白术对黄牙脱色疗效显著;对轻、中度四环素牙脱色明显,对重度四环素牙疗效欠佳.该产品对牙髓有一定刺激性,为短时性、一过性.     

Beyond冷光美白技术治疗着色牙远期疗效观察

目的:观察Beyond冷光牙齿美白仪对着色牙的远期疗效。方法:回顾性分析2009年4月～2012年8月应用Beyond冷光牙齿美白仪治疗的着色牙患者108例临床资料,并对其远期疗效进行1年期随访。结果:治疗后显效87例,有效19例,显效率80.6%,总有效率98.2%,以增龄性着色牙、轻度四环素牙疗效最好,中度四环素牙次之,氟斑牙疗效较差;治疗12个月后随访显效69例,显效率63.8%,有效21例,无效18例,总有效率83.2%。结论:Beyond冷光美白治疗着色牙时间短,牙髓刺激轻微,即刻效果显著,远期效果较好,临床应注意适应证选择,进一步提高疗效。     

应用Beyond冷光美白技术治疗着色牙56例

目的观察评价Beyond冷光美白技术对内、外源性着色牙美白的效果。方法临床应用Beyond冷光美白仪及其配套的美白剂,对各种四环素牙、氟斑牙、烟茶、咖啡等造成的着色牙进行美白疗效观察。结果治疗结束时和治疗后6个月及1a的美白效果观察,总有效率100％,尤其对牙面呈黄、黑、褐色比色为中度以下的着色牙齿,效果较好。结论Beyond冷光美白技术安全、有效,可立即收到美白效果。     

活髓着色牙冷光美白技术的临床评价

目的评价Beyond冷光美白技术对活髓牙的临床治疗效果。方法用Beyond冷光美白技术对门诊患者71例(其中四环素牙21例,氟斑牙20例,先天性黄染牙30例)进行美白治疗。用PR-650分光测色仪、Vitalescence比色板、相机照片进行美白治疗前后颜色及光泽度的对比。运用χ2检验和t检验进行统计学分析。结果(1)冷光美白可以在30min内将60%～90%的变色牙齿颜色提高5个色阶以上,牙髓刺激小,美白效果确实。(2)Vita比色和分光测色仪测试结果均显示:四环素牙色差改变明显低于氟斑牙和先天性黄染牙(P<0.05)。(3)所有病例牙齿光泽度满意度在统计学上差异无显著性(P>0.05)。结论Beyond冷光美白技术是一种可靠的美白技术,具有良好的临床效果和推广价值。     

祛氟剂+Beyond冷光美白治疗氟斑牙的疗效观察

目的 观察祛氟剂结合Beyond冷光美白漂白氟斑牙的疗效.方法 试验组40例患者以Beyond冷光美白结合祛氟剂进行漂白,对照组40例患者以牙齿美白胶家庭漂白治疗.用Vita比色板进行美白治疗前后颜色的对比.比较两种方法漂白效果.结果 治疗后,两组中轻度氟斑牙的色阶提高值和治疗有效率差异无统计学意义(P>0.05);而治疗组中重度、重度氟斑牙的色阶提高值和有效率明显高于对照组,差异有统计学意义(P<0.05).结论 祛氟剂结合Beyond冷光美白对氟斑牙脱色有效、安全、快速.     

四环素牙冷光美白疗效分析

目的：评价Beyond冷光美白术漂白四环素牙的疗效和安全性。方法：用Beyond冷光增白仪和配套增白剂对53例患者742枚四环素牙进行美白治疗,用VITA比色板做美白前后比色,比较增白效果,观察牙齿敏感程度。结果：美白显效率85%,总有效率96.2%,患者均未出现不可逆性软组织及牙齿损害。结论：Beyond冷光美白术对治疗四环素牙安全有效。     

Beyond冷光增白术的临床疗效及安全性的评价

目的:探讨Beyond冷光增白术对各类异常着色牙的临床疗效及安全性。方法:58例异常着色牙包括生理性黄牙、外源性黄牙、内源性黄牙,进行冷光增白术治疗,观察美白效果、牙面光泽度及术后牙齿敏感情况,术后1,3,6个月复查受试者牙齿的反色度。结果:牙齿增白的总有效率为88%。各种异常着色牙的显效率有明显差别。其中生理性黄牙、外源性着色牙效果最好,釉质发育不全和氟斑牙效果相近效果最差。冷光美白不影响牙面光泽度。术后病人均有不同程度的牙齿酸痛症状,但24h后都能缓解;追踪复查显示术后6个月内大多数病人的牙齿颜色保持稳定。结论:Beyond冷光增白术是一种快捷、有效、安全的增白方法。     

Beyond祛氟剂治疗氟斑牙的效果观察(英文)

目的 观察Beyond祛氟剂治疗氟斑牙的临床疗效.方法 将20例着色型氟斑牙病人的左、右侧氟斑牙分别作为该研究的实验组和对照组,实验组用Beyond祛氟剂漂白治疗,对照组采用Beyond祛氟剂联合Beyond冷光美白治疗.用Vita比色板进行美白治疗前后颜色的对比.结果 实验组与对照组的脱色显效率有显著性差异(χ2=4.556,P<0.05).两组有效率的差异无显著性(χ2=1.003,P>0.05).结论 Beyond祛氟剂对治疗着色型氟斑牙有较好的美白效果,并且无明显副作用.Beyond祛氟剂联合冷光美白治疗的疗效更显著.     

Beyond冷光美白技术治疗有色牙的疗效观察

目的:评价Beyond冷光美白技术治疗有色牙的临床疗效,同时进行不良反应观察。方法:用Beyond冷光美白仪及配套的冷光美白剂对60例有色牙进行漂白。术前用VITA比色板比色作术后对照,观察脱色效果、术中及术后牙齿敏感情况、术中牙龈损伤情况,术后1,3,6个月复查受试者牙齿的返色度。结果:黄牙组平均提高7.64个色阶,患者满意度为100%,四环素牙平均提高5.98个色阶,患者满意度为66.7%。术中及术后患者均有一定不同程度的牙齿酸痛症状,但24～72h后都能缓解;约11.8%的患者出现牙龈灼伤,24～48h后症状消失。结论:Beyond冷光美白技术是一种快捷、有效、安全的增白方法,具有良好的临床效果和推广价值。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.