共查询到20条相似文献,搜索用时 296 毫秒
1.
Background
There appear to be geographical differences in decisions to perform mastectomy or breast conserving surgery for early-stage breast cancer. This study was carried out to evaluate general surgeons' preferences in breast cancer surgery and to assess the factors predicting cancer practice in Iran. 相似文献2.
Introduction
We examined whether plasma C-reactive protein (CRP) levels at the time of diagnosis of breast cancer are associated with overall survival, disease-free survival, death from breast cancer, and recurrence of breast cancer. 相似文献3.
Introduction
Many women who survive breast cancer die of causes unrelated to their cancer diagnosis. This study was undertaken to assess factors that are related to breast cancer mortality versus mortality from other causes and to describe the leading causes of death among older women diagnosed with breast cancer. 相似文献4.
Carolyn G Marsden Mary Jo Wright Latonya Carrier Krzysztof Moroz Radhika Pochampally Brian G Rowan 《BMC cancer》2012,12(1):10
Background
The study of breast cancer metastasis depends on the use of established breast cancer cell lines that do not accurately represent the heterogeneity and complexity of human breast tumors. A tumor model was developed using primary breast tumor-initiating cells isolated from patient core biopsies that would more accurately reflect human breast cancer metastasis. 相似文献5.
Background
The relationship between breast cancer and organochlorine exposure is controversial and complex. As estrogen receptor positive and negative breast cancer may represent different entities of the disease, this study was undertaken to evaluate organochlorines influence on breast cancer risk and survival according to receptor status. 相似文献6.
Ogundiran TO Huo D Adenipekun A Campbell O Oyesegun R Akang E Adebamowo C Olopade OI 《Cancer causes & control : CCC》2012,23(4):565-574
Purpose
The relationship between overall obesity and breast cancer risk has been well recognized, but the role of central obesity in breast cancer development is uncertain. 相似文献7.
Gordon C Wishart Elizabeth M Azzato David C Greenberg Jem Rashbass Olive Kearins Gill Lawrence Carlos Caldas Paul DP Pharoah 《Breast cancer research : BCR》2010,12(1):R1
Introduction
The aim of this study was to develop and validate a prognostication model to predict overall and breast cancer specific survival for women treated for early breast cancer in the UK. 相似文献8.
Elin Karlsson Ulla Delle Anna Danielsson Björn Olsson Frida Abel Per Karlsson Khalil Helou 《BMC cancer》2008,8(1):254
Background
It is of great significance to find better markers to correctly distinguish between high-risk and low-risk breast cancer patients since the majority of breast cancer cases are at present being overtreated. 相似文献9.
Background
Stromal-epithelial interactions mediate breast development, and the initiation and progression of breast cancer. In the present study, we developed 3-dimensional (3D) in vitro models to study breast cancer tissue organization and the role of the microenvironment in phenotypic determination. 相似文献10.
Gramling R Lash TL Rothman KJ Cabral HJ Silliman R Roberts M Stefanick ML Harrigan R Bertoia ML Eaton CB 《Breast cancer research : BCR》2010,12(5):R82
Introduction
A family history of later-onset breast cancer (FHLBC) may suggest multi-factorial inheritance of breast cancer risk, including unhealthy lifestyle behaviors that may be shared within families. We assessed whether adherence to lifestyle behaviors recommended for breast cancer prevention--including maintaining a healthful body weight, being physically active and limiting alcohol intake--modifies breast cancer risk attributed to FHLBC in postmenopausal women. 相似文献11.
OBJECTIVE Breast-conserving surgery has been a standard treatment for relatively small size of breast cancer. Younger breast cancer patients have more desire to conserve their breasts. This study was to investigate the clinicopathological characteristics and prognosis of younger breast cancer patients who received breastconserving treatment in China. METHODS The data of 232 breast cancer patients who received breast-conserving treatment in Cancer Hospital of Chinese Academy of Medical Science from January Ist, 1999 to December 31st, 2005, were collected and retrospectively analyzed. According to the age, the patients were divided into 2 groups: younger group (age ≤ 35 at the time of diagnosis) and elder group (age 〉35). The clinical features of the patients in the 2 groups were compared, and their clinical characteristics, recurrence, metastasis and survival status were summarized. RESULTS In the 232 cases, younger patients accounted for 15.9% (37/232), the elder 84.1% (195/232). By December 2008, the median time of follow-up was 54 months (ranging from 2 months to 118 months). Two patients (5.41% , 2/37) in the younger group and 5 patients (2.56% 5/195) in the elder group died. The 5-year overall survival rate (OS) in the younger and elder groups was 96.08% and 97.19%, respectively (X2= 0.69, P = 0.4066). Local recurrence (LR) or distant metastasis (DM) presented in 5 patients (5/37, 13.51%) in younger group. LR or DM presented in 10 patients (10/195, 5.13%) in elder group. The 5-year disease-free survival (DFS) rate in the younger and elder groups was 82.58% and 95.52%, respectively (X2 = 4.02, P = 0.0451). Lymph node status and the age of 35 years old or younger were the prognosis factors affecting the DFS of patients who received breast-conserving treatment (OR = 3.467, 95%CI: 1.048-11.472, P 〈0.05; OR = 0.245, 95%CI: 0.069-0.863, P 〈 0.05). Lymph node status was the only prognostic factor affecting the DFS of younger group patients (OR = 7.357, 95%CI: 1.030-52.563, P 〈0.05). CONCLUSION Though the younger and elder patients have the same mid-long term survival rate, younger patients are more likely to have recurrence or metastasis than the elder patients. Breast-conserving surgery given to the younger patients especially to the younger patients with lymph nodes positive should be contemplated cautiously. 相似文献
12.
Objective
Dietary patterns have been inconsistently associated with breast cancer risk. We assessed dietary patterns in association with postmenopausal breast cancer risk using an exploratory approach. 相似文献13.
Romano Demicheli Ilaria Ardoino Patrizia Boracchi Danila Coradini Roberto Agresti Cristina Ferraris Massimiliano Gennaro William JM Hrushesky Elia Biganzoli 《BMC cancer》2010,10(1):656
Background
the study was designed to determine how tumour hormone receptor status affects the subsequent pattern over time (dynamics) of breast cancer recurrence and death following conservative primary breast cancer resection. 相似文献14.
Background
Although 2-20% of breast cancer patients develop a contralateral breast cancer (CBC), prognosis after CBC is still debated. Using a unique patient cohort, we have investigated whether time interval to second breast cancer (BC2) and mode of detection are associated to prognosis. 相似文献15.
Kim EJ Choi MR Park H Kim M Hong JE Lee JY Chun HS Lee KW Yoon Park JH 《Breast cancer research : BCR》2011,13(4):R78
Introduction
High-fat diets (HFDs) are known to cause obesity and are associated with breast cancer progression and metastasis. Because obesity is associated with breast cancer progression, it is important to determine whether dietary fat per se stimulates breast cancer progression in the absence of obesity. This study investigated whether an HFD increases breast cancer growth and metastasis, as well as mortality, in obesity-resistant BALB/c mice. 相似文献16.
Gry Kalstad Lønne Louise Cornmark Iris Omanovic Zahirovic Göran Landberg Karin Jirström Christer Larsson 《Molecular cancer》2010,9(1):76
Background
Protein kinase C (PKC) isoforms are potential targets for breast cancer therapy. This study was designed to evaluate which PKC isoforms might be optimal targets for different breast cancer subtypes. 相似文献17.
Background
Despite evidence that breast cancer screening reduces morbidity and mortality, until recently most women have not undergone regular mammogram examinations in Korea. We aimed to identify factors associated with use of breast cancer screening services. 相似文献18.
Manal El-Baradie Asmaa Salama Ola Khorshid Hoda Ismail Gerges Attia Abeer A. Bahnassy 《中德临床肿瘤学杂志》2012,11(2):89-98
Objective
Male breast cancer (MBC) represents < 1% of all breast cancers. Hormone receptors and Her-2/neu status are established prognostic factors in female breast cancer but not yet studied enough in male breast cancer. The aim of the study was to verify the clinico-pathologic profile of male patients with breast cancer including analysis of hormone receptors and Her-2/neu state and its impact on survival rate. 相似文献19.
Constantine Dimitrakakis David Zava Spyros Marinopoulos Alexandra Tsigginou Aris Antsaklis Rebecca Glaser 《BMC cancer》2010,10(1):547
Background
Correlation between circulating sex steroid levels and breast cancer has been controversial, with measurement of free, or bioavailable hormone rarely available. Salivary hormone levels represent the bioavailable fraction. To further elucidate the role of endogenous hormones in breast cancer, we aimed to assess correlation between salivary sex steroid levels and breast cancer prevalence. 相似文献20.