阑尾炎手术患者的围手术期护理干预探究

目的探讨阑尾炎手术患者围手术期采取护理干预的临床效果。方法抽取2014年6月至2015年5月在我院就诊的92例阑尾炎手术患者作为研究对象,随机分为对照组和观察组,每组各46例,对照组采用手术常规护理,观察组在手术常规护理的基础上配合围手术期护理干预,对比两组患者的术后感染率和护理满意度。结果观察组的术后感染率和并发症发生率明显低于对照组(P<0.05),差异有统计学意义;观察组的护理满意度明显高于对照组(P<0.05),差异有统计学意义。结论阑尾炎手术患者采用围手术期护理干预可以有效减少感染和并发症的发生,提高患者对护理的满意度,促进治疗效果,值得广泛应用于临床。     

围手术期护理干预对阑尾炎手术患者的临床疗效分析

目的探讨围手术期护理干预对于阑尾炎手术患者的临床作用。方法选取2013年3月至2016年3月于本院接受治疗的128例阑尾炎行手术患者,将其随机分为两组,即对照组和观察组,各64例,对照组给予围术期常规护理,观察组给予围术期护理干预模式进行,对比观察两组患者的住院时间、手术时间、术中出血量,并发症发生情况及患者护理满意度等。结果相比于对照组,观察组患者在住院时间、手术时间及术中出血量等方面均具有显著的优势,差异具有统计学意义(P<0.05)。对照组患者的并发症发生率为17.2%,显著高于观察组患者的并发症发生率(3.1%),差异具有显著性意义(P<0.05)。观察组患者的护理满意度为93.8%,显著高于对照组患者的护理满意度(71.9%),差异具有统计学意义(P<0.05)。结论对于阑尾炎手术患者在围手术期进行有效的护理干预能有效减少患者并发症发生概率,提高治疗效果,且患者满意度高,值得在临床推广采用。     

综合护理干预对高血压患者围术期焦虑及应激反应的影响

目的探讨综合护理干预对改善高血压患者围术期焦虑及应激反应的影响。方法选择患高血压择期行手术患者120例,随机分成两组,每组60例,对照组采用常规护理方式,观察组除常规护外加用综合护理干预措施,记录两组患者手术前后身体应激反应指标(心率、血压、血清皮质醇)、焦虑状态指数(SAS)的变化和护理满意度。结果观察组手术患者干预后的身体应激反应指标(心率、血压、血清皮质醇)及焦虑状态指数(SAS)均明显低于对照组,护理满意度明显好于对照组,差异具有统计学意义(P<0.05)。结论术前采用综合护理干预措施对高血压手术患者能够更好地保证高血压患者围术期的血压、心率稳定,减轻其焦虑状态,有利于提高护理服务质量。     

椎管内麻醉患者围手术期舒适护理

目的观察椎管内麻醉患者围手术期舒适护理的干预效果。方法选取我院2015年3月~2016年12月实施椎管内麻醉手术的患者75例,随机分为观察组38例及对照组37例。对照组采用常规护理,观察组采用围手术期舒适护理,观察两组患者的术中血压及心率的变化情况,疼痛程度,护理满意度及并发症发生情况。结果观察组患者的心率改变、收缩压、舒张压等波动幅度明显小于对照组,差异有统计学意义(P<0.05)。观察组患者的SAS、SDS及VAS评分明显低于对照组,与对照组相比较,差异有统计学意义(P<0.05)。观察组患者的护理满意率为92.11%,明显高于对照组的81.08%,两组比较差异有统计学意义(P<0.05)。观察组患者的并发症发生率为10.52%,明显低于对照组的29.73%,两组比较差异有统计学意义(P<0.05)。结论对椎管内麻醉患者实施围手术期舒适护理,患者疼痛情况明显减轻,护理满意度提高,减少并发症发生率,值得在临床推广应用。     

护理干预对急性阑尾炎术后并发症的影响

目的分析和探讨护理干预对急性阑尾炎术后并发症的影响。方法 36例急性阑尾炎患者随机分为对照组及观察组,各18例,采用常规护理的模式针对对照组患者进行护理,在常规护理的基础之上,采用围手术期系统护理的方式针对观察组患者进行护理。对两组患者护理满意度以及术后并发症进行比较。结果相对于对照组而言,观察组患者在并发症发生率上明显要低,差异有统计学意义（P〈0.05）;在护理满意度方面,观察组患者高于对照组,差异有统计学意义（P〈0.05）。结论针对急性阑尾炎手术患者实施围手术期的护理干预能够使其术后并发症的发生率显著降低,并且能够提升护理满意度。     

阑尾炎手术患者的围术期护理干预要点研究

目的本文主要探讨阑尾炎手术患者围术期护理干预的要点与效果。方法选择我院2013年1月至2015年1月接受阑尾炎手术的患者作为研究对象,一共有60例,随机分为观察组与对照组,各组为30例,对照组采用常规护理方法进行护理,观察组基于常规护理,采用有针对性的围手术期护理进行干预,对两组患者的手术后离床的时间、平均住院时间、术后疼痛耐受情况评级、并发症发生率、护理的满意程度。结果和对照组相对比,观察组患者对护理措施的满意程度明显更高,数据差异具有统计学的意义,P<0.05。与对照组患者相对比,观察组患者的疼痛耐受情况明显更为理想,主要表现在无痛、轻度疼痛、中度疼痛方面,其数据差异具有统计学的意义,P<0.05。结论围术期护理干预在阑尾炎手术患者治疗中具有理想的护理效果,值得临床应用与推广。     

化脓性阑尾炎腹腔镜切除术行综合护理的临床效果分析

目的探究综合护理在化脓性阑尾炎腹腔镜切除术围术期的临床应用效果。方法选取2018年6月至2019年4月在我院接受腹腔镜手术治疗的化脓性阑尾炎患者100例,采用随机数字表法进行分组,对照组与观察组各50例。观察组围术期给予综合护理,对照组仅行常规护理,分析两组手术情况,比较术后并发症及护理满意度。结果观察组患者平均手术时间及住院时间均短于对照组,差异有统计学意义(P <0.05);对照组术后并发症发生率高于观察组(P <0.05);两组患者对护理满意度存在统计学差异(P <0.05)。结论化脓性阑尾炎腹腔镜切除术围术期采用综合护理措施能够显著缩短患者手术及住院时间,减少术后并发症的发生,增加护理满意度。     

钬激光碎石取石术治疗泌尿结石围术期护理

目的：总结钬激光碎石取石术治疗泌尿结石围术期护理干预措施。方法85例行钬激光碎石术患者随机分为对照组42例,观察组43例。对照组给予常规对症护理干预,观察组制定并实施围术期护理干预措施,观察两组患者一次性成功碎石率和并发症发生情况。结果观察组一次性成功碎石率90.70%(39/43)与对照组83.33%(35/42)比较,差异无统计学意义(χ2=1.0228, P>0.05)；观察组术后并发症发生率9.30%明显低于对照组28.57%,差异有统计学意义(χ2=5.1629, P<0.05)。结论钬激光碎石取石术手术治疗效果确切,而围术期护理干预能够显著降低术后并发症的发生,在促进患者早期康复和提高手术效果方面具有非常重要的意义。     

个性化护理干预在肝胆外科围术期患者中的应用

目的探讨个性化护理干预在肝胆外科围手术期患者中应用的价值。方法选取2013年10月~2014年12月肝胆外科围手术期的患者75例,随机分为观察组38例及对照组37例。对照组给予常规护理,观察组采取个性化护理干预。对两组患者干预前及干预后抑郁自评量表(SDS)和焦虑自评量表(SAS)得分及心率、血压变化情况进行比较。并观察其护理的满意度及不良反应发生率。结果干预后观察组患者的SDS、SAS得分显著低于对照组,两组比较,差异有统计学意义(P0.05)。干预后观察组患者的收缩压、舒张压及心率显著低于对照组,两组比较,差异有统计学意义(P0.05)。观察组的护理满意率为92.11%,明显高于对照组的78.38%,两组比较,差异有统计学意义(P0.05)。观察组患者的不良反应发生率为7.89%,明显低于对照组的18.92%,两组比较,差异有统计学意义(P0.05)。结论对肝胆外科围手术期患者采取个性化护理干预,可降低其忧虑抑郁情绪,血压及心率保持稳定,减少不良反应情况的发生。     

围手术期护理干预用于阑尾炎手术护理中的临床效果评估

目的评估围手术期护理干预用于阑尾炎手术护理中的临床效果。方法选择113例阑尾炎手术患者,随机分为观察组和对照组,各57例、56例对照组给予常规护理,观察组给予围手术期护理干预。结果观察组肛门排气时间、下床活动时间均早于对照组,住院时间较对照组短,术后疼痛评分低于对照组(P<0.05);观察组并发症发生率为1.75%、对照组12.50%(P<0.05);观察组护理满意度为98.25%、对照组85.71%(P<0.05)。结论阑尾炎手术护理中采用围手术期护理干预可减轻患者术后疼痛,促进患者术后恢复。     

The effect of quinidine on the analgesic effect of codeine

Summary We have studied the hypoalgesic effect of codeine (100 mg) after blocking the hepatic O-demethylation of codeine to morphine via the sparteine oxygenase (CYP2D6) by quinidine (200 mg). The study was performed in 16 extensive metabolizers of sparteine, using a double-blind, randomized, four-way, cross-over design. The treatments given at 3 h intervals during the four sessions were placebo/placebo, quinidine/placebo, placebo/codeine, and quinidine/codeine. We measured pin-prick pain and pain tolerance thresholds to high energy argon laser stimuli before and 1, 2, and 3 h after codeine or placebo.After codeine and placebo, the peak plasma concentration of morphine was 6–62 (median 18) nmol·.l^–1. When quinidine pre-treatment was given, no morphine could be detected (<4 nmol·l^–1) after codeine. The pin-prick pain thresholds were significantly increased after placebo/codeine, but not after quinidine/codeine compared with placebo/placebo. Both placebo/codeine and quinidine/codeine increased pain tolerance thresholds significantly. Quinidine/codeine and quinidine/placebo did not differ significantly for either pin-prick or tolerance pain thresholds.These results are compatible with local CYP2D6 mediated formation of morphine in the brain, not being blocked by quinidine. Alternatively, a hypoalgesic effect of quinidine might have confounded the results.     

社区综合管理对肺结核患者治疗效果的影响

目的：探讨社区综合管理对肺结核患者治疗的效果影响。方法将结核病防治机构确诊并下放到社区管理的肺结核88例患者进行分组,分为接受社区综合管理组（干预组）56例和不接受社区综合管理组（对照组）32例,干预组除接受结核病防治机构抗结核治疗外,还接受社区综合管理（在医生护士及家庭成员面视下服药、接受专职医生和全科护士面对面上门随访至少4次、接受专职医生和全科护士对患者及家属进行有关结核病防治知识的健康教育至少1次以上）;对照组只接受结核病防治机构的抗结核治疗。结果经过社区管理综合管理及治疗6个月后,干预组治愈率达96.4%,对照组为78.1%。干预组治愈率明显高于对照组,差异具有统计学意义（P＜0.05）。结论社区综合管理可有效提高肺结核病患者治疗的依从性,提高患者的治愈率。     

The effect of carbon disulphide on the stereotypic effect of dopamine agonists

Exposure to CS₂ increased the intensityof apomorphine-induced stereotypy in male rats without increasing the reaction time. With amphetamine, an indirect agonist of dopamine, exposure to CS₂ had a more intensive effect and significantly prolonged the length of reaction.     

Cerebroprotective effect of nicergoline and interference with the anti-hypoxic effect of prostacyclin

The cerebroprotective effect of nicergoline was studied using the following experimental methods: hypobaric and anoxic hypoxia in mice, complete ischemia by decapitation in mice, incomplete ischemia by bilateral carotid ligation in rats, hemic hypoxia in rats and asphyxic anoxia in cats. Xanthinol nicotinate, vincamine, vinpocetine and cinnarizine were used as reference drugs. In hypobaric hypoxia and complete ischemia by decapitation the interaction of nicergoline with the effect of prostacyclin (PGI2) was investigated. Nicergoline showed cerebroprotective effect of varying potency in all the methods used except asphyxic anoxia. Nicergoline manifested a synergic effect with PGI2 shifting its anti-hypoxic dose-response curve to the left.     

Investigating the effect of antioxidant treatment on the protective effect of preconditioning in anesthetized rabbits

Reactive oxygen and nitrogen species are critical in preconditioning (PC). We sought to determine the effect of N-2-mercaptopropionyl glycine (MPG) on infarct size and on the oxidative status. Rabbits were exposed to 30-minute regional ischemia of the heart, which was followed by 3-hour reperfusion: (1) a control group without further intervention, (2) a PC1 group that was subjected to one cycle of PC, (3) a PC4 group that was subjected to 4 cycles of PC, (4) an MPG group that was treated with MPG for 60 minutes, starting 10 minutes before reperfusion, (5) MPG-PC1, and (6) the MPG-PC4 groups that were treated with the same dose of MPG and with 1 or 4 cycles of PC, respectively. Blood samples were drawn and collected for metabonomic analysis. In another series of experiments, 6 groups respective to the described ones were subjected to 30-minute regional ischemia of the heart and 20 minutes of reperfusion, after which pieces of heart tissue were quickly excised for malondialdehyde, nitrotyrosine, and glutathione content assessment. All PC and MPG groups developed smaller infarct size compared with control (16.5% ± 3.9%, 13.7% ± 3.1%, 18.6% ± 5.0%, 9.7% ± 2.0%, 15.0% ± 2.8% vs. 48.05% ± 7.2%; P < 0.05). MPG did not prevent lipid peroxidation and nitrotyrosine formation but enhanced the glutathione content. PC and MPG induced similar nuclear magnetic resonance changes. Long MPG infusion reduces the infarct size without abolishing the effect of PC, providing novel insights into the activity of MPG in PC.     

普鲁卡因在大咯血患者中的疗效和不良反应的观察

目的总结应用普鲁卡因治疗大咯血的疗效和不良反应。方法回顾漯河市中心医院2005年7月至2008年5月收治的140例大咯血患者应用普鲁卡因治疗的临床资料。结果大部分大咯血患者应用普鲁卡因疗效确切,治愈率占75%。7例患者出现不同程度的不良反应,不良反应发生率占5%,严重者可危及生命。结论普鲁卡因在大部分大咯血患者中应用安全、有效,但也应注意其少见的不良反应。一旦出现,应积极处理。     

右美托咪定不同给药方式对腹腔镜子宫肌瘤剔除术麻醉效果的影响分析

目的 分析右美托咪定不同给药方式对腹腔镜子宫肌瘤剔除术麻醉效果的影响.方法 60例腹腔镜宫肌瘤剔除术患者,随机分为对照组和试验组,各30例.对照组给予持续泵注右美托咪定,试验组术前15 min给予单次缓慢静脉滴注右美托咪定.比较两组患者机械痛阈值评分、苏醒期躁动评分及拔管、恢复定向力、麻醉恢复、应答及生命指征恢复稳定时...     

Probenecid potentiates the hyperglycaemic effect but reduces the diuretic effect of frusemide in mice.

The effect of probenecid on frusemide-induced diuresis and hyperglycaemia was studied in mice. Probenecid, a known inhibitor of tubular secretion of organic anions in the kidney, strongly reduced the diuretic response to frusemide (25 or 200 mg kg-1 body weight). This effect of probenecid appeared to be dose-dependent up to 240 mg kg-1 body weight, at least at the lower concentration of frusemide. Pretreatment with probenecid (240 mg kg-1 body weight) potentiated the hyperglycaemic effect of frusemide (25 or 200 mg kg-1 body weight). The results show that probenecid has opposite effects on frusemide-induced diuresis and hyperglycaemia in mice. It is suggested that the acute hyperglycaemic effect of frusemide is not directly linked to diuresis.