Immunological reactions in acute destructive pneumonia in children

Clinical examinations of 512 children with acute destructive pneumonia have shown high incidence (27.1%) of medicamentous allergic reactions, high level of sensibilization to antigens of the lung tissue. The use of small doses of polyglucin in experiment prevents the appearance of anaphylactic shock, and in patients with a destructive pneumonia it made the incidence of medicamentous allergic reactions 7 times less frequent.     

The use of ultraviolet-irradiated blood reinfusion in the combined treatment of destructive pancreatitis]

The results of treatment of the patients with acute destructive pancreatitis who in the complex underwent reinfusion of the blood irradiated with ultra-violet rays were analysed. The given method permitted to improve the results of treatment, as it was witnessed by rapid decrease in intoxication, normalization of clinical and laboratory indices. The lethality reduced by 1.1%, incidence of complications--by 31.2%. In patients with purulent pancreatitis, the treatment has proved to be ineffective.     

Surgical treatment of the sequelae of acute destructive pneumonia in children

The authors present data on 142 children with sequellae of acute destructive pneumonia. In 101 patients there were 105 operations without lethal outcomes. Timely surgical measures were found to give better results of the treatment of acute destructive pneumonias.     

Autotransfusion of UV-irradiated blood in the treatment of suppurative peritonitis in children

The inclusion of autotransfusions of the UV-irradiated blood in the complex of therapeutic measures for the treatment of children with peritonitis resulted in substantial shortening of the time of treatment and in a less volume of the infusion therapy. The autotransfusion of the UV-irradiated blood brings about positive dynamics of the ABC of blood, the content of immunoglobulins in plasma becomes normal within 5-6 days. The non-specific resistance factors were found to be activated.     

Effect of intravascular laser therapy on the rheologic properties of blood in children with bilateral destructive pneumonia]

The effect of intravascular blood irradiation with helium-neon laser in 20 children with bilateral destructive pneumonia at a dose of 10-30 J/cm2 for a course of treatment on indices of hemostasis and rheologic blood properties was studied. Decrease in blood viscosity, hypocoagulative effect of intravascular laser therapy, normalization of clinico-roentgenologic data were revealed.     

Intrapleural sorption detoxication in the combined treatment of acute destructive pneumonia in children

The pathogenetic substantiation and technique of intrapleural sorption detoxication (IPSD) based on the use of high-dispersed silicone dioxide (trade mark "AEROSIL") are presented. Use of IPSD in the complex of treatment of 25 children with complicated forms of acute destructive pneumonia permitted to shorten the duration of intoxication syndrome, sanation of suppurative foci, stay of the patients at a hospital.     

Autotransfusion of mediastinal blood in cardiac surgery

A series of 135 adults undergoing cardiac surgery was randomized to an autotransfusion group (n = 67) or a control group (n = 68). In the autotransfusion group mediastinal blood was collected and reinfused during the first 6 postoperative hours. Blood from the reservoir was taken for bacteriologic culture at the end of that time. The postoperative blood was comparable in the two groups. The average requirement of bank blood was 2.7 units in the autotransfusion group and 3.3 units in the controls (p less than 0.05). The average volume of autotransfusion blood was 336 ml. There were no clinical infections in the autotransfusion group, although 19% of the cultures were positive, and no apparent alteration of the coagulation mechanisms arose from infusion of autologous blood. No clinically significant intergroup differences were found in hematologic, renal or hepatic parameters, neurologic function or use of antibiotics.