基于博弈论的我国制药工业创新驱动研究

目的通过对创新驱动战略的意义和我国制药工业现状进行分析,找到我国制药工业实施创新驱动战略的主要障碍,为相关部门提供政策建议。方法建立博弈模型,分析我国制药企业创新决策的现状。结果与结论医药不分是我国制药企业实施原研型创新的最大障碍,故医药分业是必要的。只有实行医药分业,制药企业才能选择原研型创新,从而有利于我国创新驱动战略的实施。     

国外和我国港台地区“医药分业”现状及启示

随着我国医疗卫生体制改革的不断深入,越来越多的有识之士都将"降低医疗费用、纠正医药行业不正之风和促进医药流通与医疗保障改革"的希望寄托在实施"医药分业"的政策上.为了吸取国外和我国港台地区的经验教训,使医药体制改革少走弯路,本文对国外和我国港台地区实施"医药分业"政策的理论与实践进行了简要综述.     

解读政策分析医药市场、抓住机遇研究药物创新

我国的相关政策与制度一直左右着医药市场,这已经成为业内共识。医药市场的发展是由药品生产、药品流通与药品使用等组成,产业链中医药、医疗和医保缺一不可。本综述通过对国家相关政策的解读和理解,深度分析医药市场的现状与发展趋势,希望医药行业利用已经到来的十年黄金发展时机,抓住药物创新与药用辅料发展的机遇,切实提高国内临床用药水平。     

医药改革政策对江苏医药经济的影响分析

近年来,随着社会大众对医药卫生问题的广泛关注,我国政府相继颁布了一系列医药改革政策。针对这些政策实施的效果,运用政策评价方法中的前后对比分析法,具体分析了医药改革政策的推行对江苏医药经济和中医药、生物医药、化学药发展的影响。     

近年来我国药品监管政策分析

近十年是我国医药改革的重点阶段,国家有关部委出台了许多政策,对医药领域的各方各面进行监管.本文重点探讨国家食品药品监督管理局的部分药品监管政策,从政策出台的背景、有关措施、实施效果及问题、可能的对策等方面系统归纳.     

我国医药制造业不同子行业合作创新资金投入影响因素的实证研究

本文旨在明确我国医药制造业不同子行业合作创新资金投入的影响因素及其作用机制，为提升我国医药制造业不同子行业合作创新资金投入水平提供参考。基于2009—2019年我国医药制造业不同子行业相关指标数据，使用因子分析方法实证分析所归纳因素对其合作创新资金投入的影响。研发资金内部投入、科技活动人员投入、新产品开发投入、盈利水平、有效发明专利和政府资助对我国医药制造业不同子行业合作创新资金投入均为正向影响，这种促进作用体现为生物药品制造业>化学药品制造业>中成药制造业；而企业开放度对我国医药制造业不同子行业合作创新资金投入均为负向影响。     

国内外医药政策实施效果评估研究综述

目的进一步提高我国医药政策评估的研究水平。方法结合政策评估的理论,参考国内外医药政策实施效果评估的研究文献,进行对比研究。结果与结论国内医药政策评估应吸取国外在政府参与度、理论研究和指标体系、评估后政策修订等方面的经验,更好地     

我国政府医药科技投入对企业研发支出影响的实证分析

目的:为提高我国政府医药科技投入的使用效率,促进企业增加研发投入,提高创新能力提供参考性政策建议。方法:构建多元线性回归模型,分析近年来我国政府医药科技投入对企业研发支出的影响,并进行相关性分析。结果与结论:在样本期内政府医药科技投入对企业研发支出具有挤出效应,挤出效应最终反映在企业委托科研机构研发经费支出上;政府向医药科研机构拨款对医药企业研发支出影响不显著。建议通过调整医药科研机构研发投入结构,提高医药科研机构知识产权保护意识,调动"供体"活力、激发"受体"动力、完善"媒体"建设等措施,消除政府投入的挤出效应,发挥杠杆效应。     

我国大中型医药制造企业的技术创新能力研究

该文通过对医药企业技术创新活动有关数据的研究，客观评估了我国大中型医药制造企业技术创新能力的水平、差距，为政府有关部门制定产业创新政策及医药制造企业可持续发展战略提供参考。     

"以药养医"问题与渐进式的医药分业决策

目的 探讨目前实行医药分业的可行性.方法 研究"以药养医"背景与问题,分析国外医药分业的概况,对我国医药分业政策进行评价.结果和结论 目前我国医药分业条件还不成熟,医药分业政策不可能从根本上切断医疗机构与药品营销之间的经济利益联系,"医药分业"政策是经济利益的转移,医药分业政策无法解决药价虚高问题,对降低药品费用作用有限.建立医药合并的统一行政管理体制,相关利益集团参与政策制定;解决"以药养医"问题,治理药价虚高是关键;控制医药费用,卫生配套改革应跟进.     

Degraded and undegraded carrageenans and experimental gastric and duodenal ulceration

The prevention of histamine-induced gastric and duodenal ulceration in the guinea-pig has been examined using a series of undegraded and degraded carrageenans. Undegraded carrageenans were active at lower doses than degraded carrageenans. The high viscosity of the undegraded carrageenans in solution prevented their use in larger doses. Degradation of carrageenan without serious loss of sulphate, gives a product which allows the dose to be increased to an extent that its effect more than offsets the slight loss in activity caused by the degradation. No single feature of carrageenan structure can be related to anti-ulcer activity although degradation, and hence reduction of molecular size, generally reduces activity. Sulphate contents over 30% have little apparent effect on activity; κ-carrageenans were not consistently different in anti-ulcer activity from Λ-carrageenans. This contrasts with the antipeptic activity of carrageenans where κ-carrageenans are less active than their Λ-counter-parts. As with antipeptic activity, the degree of anti-ulcer activity is probably determined by a combination of structural features which includes molecular size and polyanionic properties.     

Affective and Anxiety Disorders and Alcohol and Drug Dependence:

Depression and anxiety frequently coexist in patients with substance use disorders. This clinically-oriented article examiens the relationship between these conditions and emphasizes data showing that substances of abuse can cause signs and symptoms of both depression and anxiety. These substance-related syndromes appear to have a different course and prognosis than uncomplicated, independent anxiety and major depressive disorders, and clinicians should consider the role of alcohol and other drugs in all patients presenting with these complaints. The authors will also outline an approach for diagnosing and managing patients with the combination of a substance use and depressive or anxiety disorder.     

Alcohol and Substance Use and Abuse in Women and Children

No abstract available for this article.     

Synthesis and anti-nociceptive and anti-inflammatory effects of gaultherin and its analogs

The synthesis of gaultherin (1) and its analogs was carried out to provide 11 glycosides under phase-transfer catalytic conditions. The activities of all synthesized compounds were evaluated by nitric oxide production inhibitory assay in vitro. Methyl 2-O-(4-O-β-d-galactopyranosyl)-β-d-glucopyranosylbenzoate (5f) showed significantly anti-nociceptive and anti-inflammatory effects by the evaluation in vivo. Structure–activity relationships within these compounds were discussed.