共查询到20条相似文献,搜索用时 112 毫秒
1.
目的:调查初发急性淋巴细胞白血病(ALL)患儿使用左旋门冬酰胺酶(L-Asp)化疗时营养状况的改变,评估添加高蛋白、高中链甘油三酯(MCT)特殊医学用途配方食品(FSMP)作为口服营养补充对改善其营养状况及临床结局的作用。方法:前瞻性纳入2014年7月至2015年4月在上海儿童医学中心确诊ALL并使用含L-Asp的化疗... 相似文献
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目的 对比左旋门冬酰胺酶、培门冬酶对急性淋巴细胞白血病(ALL)患儿的治疗效果。方法 回顾性收集2016年6月至2022年9月无锡市儿童医院收治的所有ALL患儿临床资料,根据治疗方法不同随机选取左旋门冬酰胺酶组和培门冬酶组,例数各37例。两组均进行常规基础治疗,在此基础上,左旋门冬酰胺酶组采用左旋门冬酰胺酶进行治疗,培门冬酶组采用培门冬酶进行治疗,两组均治疗46天,并随访3个月。统计两组治疗46天的临床疗效及治疗期间不良反应发生情况,比较两组治疗前、治疗21天、46天后、随访3个月后糖脂代谢指标及治疗前、治疗21天、46天后细胞因子、凝血功能、肝功能。结果 治疗46天后,与左旋门冬酰胺酶组比较,培门冬酶组总缓解率差异无统计学意义(P>0.05),而完全缓解率更高(χ2=4.874,P<0.05)。治疗前及治疗21天、46天后、随访3个月后,两组血清胰岛素、C肽水平呈降低趋势,不同时间点比较,差异具有统计学意义(P<0.05);治疗21天后,培门冬酶组高于左旋门冬酰胺酶组(t=3.372、3.704,P<0.05)。治疗46天后、随访3个月后... 相似文献
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目的探讨急性淋巴细胞性白血病(ALL)患儿化疗期间营养状况与化疗并发症的相关性。方法选择2021年1~6月在南方医科大学南方医院化疗的60例ALL患儿为研究对象,评估患儿化疗期间营养状况分为营养不良组10例、营养正常组36例和营养过剩组14例。分析不同营养状况患儿化疗并发症发生情况及两者相关性。结果三组粒细胞缺乏率均为100.00%,营养不良组感染率高于营养正常组、营养过剩组,差异有统计学意义(P<0.05),营养不良组肝损伤率略高于营养正常组、营养过剩组,差异无统计学意义(P>0.05);营养正常组与营养过剩组感染、肝损伤发生率比较,差异无统计学意义(P>0.05);营养不良组粒细胞缺乏持续时间为(11.62±3.24)d,长于营养正常组的(6.62±2.14)d与营养过剩组的(7.01±2.30)d,差异有统计学意义(P<0.05);营养正常组与营养过剩组粒细胞缺乏持续时间比较,差异无统计学意义(P>0.05);营养状况与感染、粒细胞缺乏持续时间呈负相关(r=-0.317、-0.284,P<0.05);营养状况与肝损伤发生率无相关性(r=-0.199,P>0.05)。结论ALL患儿化疗期间营养状况与感染发生、粒细胞缺乏持续时间密切相关。 相似文献
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《现代医院》2017,(9):1399-1401
目的探讨综合护理干预对提高PICU机械通气鼻饲患儿营养状况的应用效果。方法选择未开展综合护理干预的2015年1月1日—2016年1月31日的30例机械通气鼻饲患儿设为对照组,将2016年2月1日—2017年2月28日已开展综合护理干预的30例同病区同类患儿设为观察组。观察期为7天,7天后分别对两组患儿的鼻饲管非计划拔管率、人体指标、血生化营养指标进行比较分析。结果对机械通气鼻饲患儿实施综合护理干预后,观察组患儿鼻饲管非计划拔管率明显低于对照组,而体质指数、总蛋白质、白蛋白及血红蛋白水平显著优于对照组(P<0.05)。结论综合护理干预能提高机械通气饲管患儿的鼻饲管理,保证患儿的营养、水分、药物的安全供给,减少拔管意外,提高营养状况和治疗效果。 相似文献
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目的:讨论针对性饮食护理对肿瘤患者化疗期间营养状况的影响.方法:选择我院2019年1月至2020年1月收治的84例接受化疗的肿瘤患者,随机分为对照组(施以常规护理)与研究组(施行针对性饮食护理)各42例,比对干预结果.结果:从营养指标水平入手分析,干预前比较差异不明显,P>0.05;干预后优于干预前,P<0.05;研究... 相似文献
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目的 观察胃十二指肠溃疡患者应用饮食护理干预对营养状况及生活质量的影响.方法 自我院于20219.11-2020.11期间收治的胃十二指肠溃疡患者中抽取80例按照随机数字表法进行分组,主要分为常规组(n=40,常规护理干预)及干预组(n=40,饮食护理干预),将其营养状况及生活质量进行比较.结果 护理前两组健康调查简表... 相似文献
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《社区医学杂志》2017,(8)
目的探究饮食护理对溃疡性结肠炎患者营养状况的影响。方法选择2014年4月—2016年6月收治的94例溃疡性结肠炎患者作为研究对象,随机分为对照组和研究组各47例。对照组给予常规护理,研究组给予加强饮食护理。对比两组患者血清白蛋白(serum albumin,ALB)、前白蛋白(prealbumin,PA)含量以及护理前后营养状况。计量资料组间比较采用t检验,组内比较采用配对t检验,等级资料采用秩和检验,P0.05为差异有统计学意义。结果护理后,研究组ALB、PA含量分别为(40.15±2.81)g/L、(301.29±57.92)mg/L,均明显优于对照组的(35.17±3.72)g/L、(278.34±53.17)mg/L,差异均有统计学意义(均P0.05)。护理后,研究组营养状况优于对照组,差异有统计学意义(P0.05)。结论对溃疡性结肠炎患者进行饮食护理可以较好改善其营养状况,提高ALB、PA含量。 相似文献
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目的:讨论针对性饮食护理对肿瘤患者化疗期间营养状况的改善作用.方法:选择90例在2019年5月到2020年5月治疗的肿瘤患者,均使用化疗治疗,根据随机数字法分为两组,使用针对性饮食护理的为实验组,使用常规护理的为对照组.结果:两组的ALB,HGB,LY等营养指标水平,PG-SGA评分,护理满意率相比,差异较大(P<0.... 相似文献
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目的:研究饮食护理对食管癌患者放疗期间营养状况改善的效果及护理满意度.方法:实验区间为2019.3——2020.3从到本院治疗的食管癌病人中挑选实验对象,共计70例参与本次研究,经临床诊断符合实验指征.按照护理模式的差异性来将对象分为使用常规护理组和使用饮食护理的护理组,前者设为对照组,后者设为实验组,共同了解并比较组... 相似文献
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【目的】 了解深圳市学龄前儿童饮食行为对儿童营养状况的影响。 【方法】 于2009年3-6月份采用分层整群抽样方法,自行设计调查问卷,统一标准,统一培训,以一人一表调查深圳市学龄前儿童10 138人,有效问卷8 920份。 【结果】 深圳市学龄前儿童单纯性肥胖的发生率为9.0%,体重低下发生率为0.6%,生长迟缓发生率为1.6%,消瘦发生率为0.9%,贫血发生率为2.53%。吃饭时看电视听音乐或玩玩具,吃饭时间越短,不愿咀嚼固体食物,饭前吃零食,外出就餐次数多,是儿童单纯性肥胖发生的危险因素。吃饭时间不固定、不愿咀嚼固体食物,含饭、拒食,外出就餐次数少,是儿童营养不良或贫血发生的危险因素。 【结论】 深圳市学龄前儿童的营养状况较好,其饮食行为对其营养状况影响明显:某些饮食行为分别是肥胖、体重低下、生长迟缓、消瘦和贫血发生的危险因素。 相似文献
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目的 评估低蛋白饮食对3/4期慢性肾脏病(CKD)患者肾功能水平及营养状况的影响.方法 将34例3/4期CKD患者随机分为A组(n=14)和B组(n=20),分别给予0.6 g·kg~(-1)·d~(-1) 和0.8 g·kg~(-1)·d~(-1)蛋白质摄入量,对两组患者个体化跟踪指导6个月,测定治疗前后人体测量指标及血生化指标,进行人体营养状况整体评价和24 h膳食回顾调查.结果 A组治疗后血肌酐值水平明显下降(P=0.010),白蛋白水平明显升高(P=0.042),热能(P=0.018)和碳水化合物(P<0.001)的摄入均较治疗前明显提高.通过营养干预,整体、A组和B组患者营养不良发生率比治疗前分别下降了14.7%、7.2%和21.1%.结论 0.6 g·kg~(-1)·d~(-1)蛋白质摄入量及用小麦淀粉代替部分主食的饮食方案可明显提高3/4期CKD患者碳水化合物和热能的摄入量,改善其营养状况和肾功能. 相似文献
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C. E. Weekes A. Spiro† C. Baldwin† K. Whelan† J. E. Thomas† D. Parkin‡ & P. W. Emery† 《Journal of human nutrition and dietetics》2009,22(4):324-335
Background: The association between malnutrition and poor clinical outcome is well-established, yet most research has focussed on the role of artificial nutritional support in its management. More recently, emphasis has been placed on the provision of adequate nutritional care, including nutritional screening and the routine provision of food and drink. The aim of this literature review is to establish the evidence for the efficacy of interventions that might result in improvements in nutritional and clinical outcomes and costs.
Methods: A structured literature review was conducted investigating the role of nutritional care interventions in adults, and their effects on nutritional and clinical outcomes and costs, in all healthcare settings. Ten databases were searched electronically using keywords relating to nutritional care, patient outcomes and healthcare costs. High quality trials were included where available.
Results: Two hundred and ninety-seven papers were identified and reviewed. Of these, only two randomised, controlled trials and six other trials were identified that addressed the major issues. A further 99 addressed some aspects of the provision of nutritional care, although very few formally evaluated nutritional or clinical outcomes and costs.
Conclusions: This review reveals a serious lack of evidence to support interventions designed to improve nutritional care, in particular with reference to their effects on nutritional and clinical outcomes and costs. The review suggests that screening alone may be insufficient to achieve beneficial effects and thus more research is required to determine the most cost-effective interventions in each part of the nutritional care pathway, in a variety of healthcare settings and across all age ranges, to impact upon nutritional and clinical outcomes. 相似文献
Methods: A structured literature review was conducted investigating the role of nutritional care interventions in adults, and their effects on nutritional and clinical outcomes and costs, in all healthcare settings. Ten databases were searched electronically using keywords relating to nutritional care, patient outcomes and healthcare costs. High quality trials were included where available.
Results: Two hundred and ninety-seven papers were identified and reviewed. Of these, only two randomised, controlled trials and six other trials were identified that addressed the major issues. A further 99 addressed some aspects of the provision of nutritional care, although very few formally evaluated nutritional or clinical outcomes and costs.
Conclusions: This review reveals a serious lack of evidence to support interventions designed to improve nutritional care, in particular with reference to their effects on nutritional and clinical outcomes and costs. The review suggests that screening alone may be insufficient to achieve beneficial effects and thus more research is required to determine the most cost-effective interventions in each part of the nutritional care pathway, in a variety of healthcare settings and across all age ranges, to impact upon nutritional and clinical outcomes. 相似文献
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A community-based longitudinal study was conducted in the Manya Krobo District of the Eastern Region of Ghana with the objective of assessing how caregiving practices influence nutritional status of young children in Ghana. The study subjects were one hundred mothers with infants between the ages of 6 and 12 months. Each child was visited at home monthly for a period of six months. On each visit, information was collected on caregiver household and personal hygiene, child''s immunization status, child''s dietary diversity, caregiver responsiveness during feeding, caregiver hygienic practices related to feeding and child''s weight and length. At the end of the study, summary scores were generated for each variable and quality of care practice determined based on their distribution. Classification of child nutritional status was based on z-scores for both weight-for-age and length-for-age. The results revealed that caregivers who exhibited better quality of care practice had well-nourished children. Such caregivers were more likely to practice good household and personal hygiene than those of poorly nourished children (97.1% vs 31.8%, p<0.001). They were also more likely to complete their children''s immunization schedules (88.2% vs 62.2%, p< 0.001), provide good quality diets from highly diversified sources (79% vs 23%, p<0.001), exhibit high responsiveness during feeding (100% vs 22.7%, p<0.001) and feed under hygienic conditions (100% vs 22.7%, p<0.001). Based on the findings it was concluded that good caregiving practices are associated with improved child nutritional status. 相似文献
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目的研究平衡膳食对山区学龄儿童营养状况的影响。方法2004年11月份在某山区选取二年级小学生60名,分为2组,每周5天在学校进食3餐,干预组根据营养素推荐摄入量配餐,对照组则保持日常膳食模式,实验期为30天,观察实验前后两组儿童营养状况的变化。结果干预组膳食结构合理,营养素供给充足,儿童的体格发育和营养状况得到明显改善,对照组由于膳食结构不合理,营养素摄入量普遍低下,影响了儿童的正常生长发育。结论在贫困地区以食物为基础的营养干预可改善儿童生长发育和营养状况。 相似文献
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【目的】 了解安徽省贫困地区学龄儿童膳食现况,寻找影响营养状况的原因,为进行营养干预措施提供科学依据。 【方法】 采取体格检查和问卷调查相结合的方法,对安徽省贫困地区学龄儿童膳食状况进行测量和调查。 【结果】 安徽省贫困地区学龄儿童营养不良率为81.7%,超重率为1.8%,多因素分析显示,营养不良与性别(OR=0.865,P=0.038)、年级和吃早餐的频率(OR=1.727,P=0.001)有关,超重与性别(OR=2.359,P=0.002)、父母未外出务工(OR=1.478,P=0.048)和年级有关。 【结论】 在安徽省贫困地区学龄儿童中营养不良情况非常普遍,应当积极开展营养健康教育,帮助学龄儿童获取营养基础知识、树立与合理营养有关的正确态度、培养健康的饮食行为。 相似文献
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Margaret A. Allman 《Journal of human nutrition and dietetics》1990,3(4):225-232
There is a high prevalence of the features of protein-energy malnutrition among patients with chronic renal failure undergoing maintenance haemodialysis. Poor food intakes are only partly responsible. The disease state itself and renal replacement therapy are contributing factors to the development of malnutrition. Hypogeusia, anorexia and impaired digestion of nutrients have been reported. Changes in the hormonal environment may result in poor utilization and altered metabolism of nutrients. The requirements for nutrients may be different to those in normal healthy individuals. However, despite the effects of unalterable non-dietary factors on nutrition, it is possible to manipulate dietary intakes to improve the nutritional status. 相似文献
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