北京市男男性行为者安全套使用社会规范与无保护性肛交关系的研究

Objective To understand the prevalence of and factors associated with unprotected anal intercourse(UAI)among men who have sex with men(MSM)in Beijing.Methods Five hundred MSM were recruited for a survey using Respondent Driven Sampling (RDS)method, from September to October in 2009. A computer-assisted, interviewer-administered questionnaire was used to gather information including demographics, sexual behaviors and condom use social norms(a scaled number). Variables were evaluated by using RDSAT and SAS software.Results Mean age of the participants was 30.6 years, with 96.0% of them as Han ethnicity and68.5% having had at least high school or higher education level. 72.8% of them were unmarried, with 61.7% of them identified themselves as homosexual, 61.2% had ＞ 1 male partners in the past six months, and the prevalence of UAI was 42.0%. Significant bivariate predictors of UAI would include condom use social norms score, role for anal sex with male sex partner, number of male sexual partners in the past 6 months and amount of alcohol consumed. In multivariable analysis, UAI was associated with a higher condom use social norms score(AOR= 1.2, 95%CI: 1.1-1.3), receptive anal intercourse(AOR=2.0, 95%CI: 1.3-3.2)and drinking alcohol more than 3 times per month in the past 12 months(AOR=1.6, 95%CI: 1.1-2.5). Conclusion The prevalence of UAI was high in the MSM community in Beijing, suggesting that efforts should be targeting on how to make the condom use a social norm and being promoted.     

北京市男男性行为者安全套使用社会规范与无保护性肛交关系的研究

Objective To understand the prevalence of and factors associated with unprotected anal intercourse(UAI)among men who have sex with men(MSM)in Beijing.Methods Five hundred MSM were recruited for a survey using Respondent Driven Sampling (RDS)method, from September to October in 2009. A computer-assisted, interviewer-administered questionnaire was used to gather information including demographics, sexual behaviors and condom use social norms(a scaled number). Variables were evaluated by using RDSAT and SAS software.Results Mean age of the participants was 30.6 years, with 96.0% of them as Han ethnicity and68.5% having had at least high school or higher education level. 72.8% of them were unmarried, with 61.7% of them identified themselves as homosexual, 61.2% had ＞ 1 male partners in the past six months, and the prevalence of UAI was 42.0%. Significant bivariate predictors of UAI would include condom use social norms score, role for anal sex with male sex partner, number of male sexual partners in the past 6 months and amount of alcohol consumed. In multivariable analysis, UAI was associated with a higher condom use social norms score(AOR= 1.2, 95%CI: 1.1-1.3), receptive anal intercourse(AOR=2.0, 95%CI: 1.3-3.2)and drinking alcohol more than 3 times per month in the past 12 months(AOR=1.6, 95%CI: 1.1-2.5). Conclusion The prevalence of UAI was high in the MSM community in Beijing, suggesting that efforts should be targeting on how to make the condom use a social norm and being promoted.     

北京市大学在校生男男性行为者HIV感染状况及其相关危险陛行为调查

目的 了解北京市大学在校生男男性行为者的HIV感染状况及其相关危险性行为.方法 研究对象主要通过网络招募,采用自填式问卷调查.问卷内容包括人口学信息与艾滋病相关危险行为等.问卷完成后采集血液样本进行HIV血清学检测.单因素分析采用X2检验,多因素分析采用logistic同归.结果 研究成功招募157人.平均年龄为(22.7±2.8)岁,少数民族占12.1%,77.7%自我认同为同性恋.98.1%曾有肛交行为,73.9%报告肛交是常采用的性行为方式.157人中近6个月有58.6%发生过无保护肛交,有58.0%口交时从不使用安全套,其中59.2%存在多性伴(性伴数≥2)行为.近50.0%认为自己不可能感染HIV或者风险很小,检测发现HIV阳性率为2.5%.logistic回归分析结果 显示,曾与陌生人发生性行为(OR=13.10)、了解"肛交时做主动方比做被动方感染HIV风险小"(OR=3.37)以及曾去同性恋酒吧(OR=2.49)是近6个月发生多性伴行为的独立危险因素.结论 大学在校生男男性行为者无保护肛交和多性伴行为较普遍.亟需开展有针对性的干预活动,预防HIV在该人群中传播.

Abstract：

Objective To assess the prevalence of HIV and risky sexual behaviors among university students who have sex with men(MSM)in Beijing.Methods MSM students in the universities were mainly recruited via internet.Questionnaires were self-administered to collect social demographic information and AIDS-related risky sexual behaviors.After completing the questionnaire,blood sample was collected to determine HIV infection through serological testing.X2 test and logistic regression were employed for univariate and multivariate analysis,respectively.Results A total of 157 students were recruited with mean age of 22.7±2.8 years old,12.1%of them were minorities and 77.7% were self-identified as homosexual.98.1% had engaged in anal intercourse(AI)in their lifetime and 73.9%reported that AI was common sexual behavior they often practised.In the past 6 months,58.6% had ever had unprotected anal intercourse(UAI),58.0% never used condoms during oral intercourse,and 59.2% had multiple sex partners(≥2).Nearly half of them believed that they were at low or no risk of contracting HIV and the prevalence of HIV infection was 2.5%.Data from logistic regression analysis showed that ever having had sex with a casual partner in a lifetime (OR=13.10).understanding that serving an insertive role had less risk than being receptive during the AI (OR=3.37),and ever having been to a gay bar(OR=2.49)was independently related to having multiple sex partners in the past 6 months.Conclusion Despite the extensive programs on education,behaviors regarding UAI and ever having had multiple sex partners were silll commonly seen among university MSM students.Interventions were needed to prevent HIV transmission in this population.     

北京市男男性行为者安全套使用社会规范与无保护性肛交关系的研究

目的 了解北京市男男性行为者(MSM)无保护性肛交发生情况及其与社区安全套使用社会规范的关系.方法 2009年9-10月采用应答驱动抽样方法(RDS)在北京市MSM中开展调查,问卷采用计算机辅助调查员访谈式,内容包括人口学、性行为学特征及安全套使用社会规范,使用RDSAT和SAS进行统计学分析.结果 500名MSM平均年龄30.6岁,96.0%为汉族,高中及以上文化程度者占68.5%,72.8%未婚.61.2%最近6个月男性性伴数量＞1;42.0%的调查对象最近一次发生过无保护性肛交.多因素统计分析表明,差异有统计学意义的变量包括安全套使用社会规范计分低(AOR=1.2,95%CI:1.1-1.3),肛交中非主动角色(AOR=2.0,95%CI:1.3-3.2)和近12个月饮酒次数＞3次/月(AOR=1.6.95%CI:1.1-2.5).MSM社区安全套使用社会规范量表内部一致性检验克朗巴赫系数为0.93.结论 北京市MSM无保护性肛交行为发生率较高,应充分发挥MSM社区内社会规范的作用,减少无保护性肛交行为的发生.

Abstract：

Objective To understand the prevalence of and factors associated with unprotected anal intercourse(UAI)among men who have sex with men(MSM)in Beijing.Methods Five hundred MSM were recruited for a survey using Respondent Driven Sampling (RDS)method, from September to October in 2009. A computer-assisted, interviewer-administered questionnaire was used to gather information including demographics, sexual behaviors and condom use social norms(a scaled number). Variables were evaluated by using RDSAT and SAS software.Results Mean age of the participants was 30.6 years, with 96.0% of them as Han ethnicity and68.5% having had at least high school or higher education level. 72.8% of them were unmarried, with 61.7% of them identified themselves as homosexual, 61.2% had ＞ 1 male partners in the past six months, and the prevalence of UAI was 42.0%. Significant bivariate predictors of UAI would include condom use social norms score, role for anal sex with male sex partner, number of male sexual partners in the past 6 months and amount of alcohol consumed. In multivariable analysis, UAI was associated with a higher condom use social norms score(AOR= 1.2, 95%CI: 1.1-1.3), receptive anal intercourse(AOR=2.0, 95%CI: 1.3-3.2)and drinking alcohol more than 3 times per month in the past 12 months(AOR=1.6, 95%CI: 1.1-2.5). Conclusion The prevalence of UAI was high in the MSM community in Beijing, suggesting that efforts should be targeting on how to make the condom use a social norm and being promoted.     

三种HIV抗体确证试剂盒检测早期感染的比较

目的 比较3种HIV抗体确证试剂盒检测HIV早期感染的性能.方法 对5份HIV抗体阳性血浆样品进行10倍系列稀释,然后用ELISA检测.对检测结果呈阳性反应的稀释样品分别用3种HIV抗体确证试剂盒进行检测以测试其灵敏度,所用试剂盒包括北京万泰公司的HIV 1+2型抗体检测试剂盒(万泰RIBA)、新加坡MP公司的HIV 1+2型抗体检测试剂盒(MP-WB)和比利时Innogenetics公司的INNO-LIA TM HIV Ⅰ/ⅡScore(INNO-LIA).用这些试剂盒检测11套HIV抗体阳转血清盘中ELISA试验呈阳性反应的样品(共48份).结果 对HIV抗体阳性稀释样品的检测结果显示,当5份样品在稀释100倍时,万泰RIBA均检测出阳性结果.在ELISA试验呈阳性反应的48份HIV抗体阳转血清盘样品中,万泰RIBA、MP-WB和INNO-LIA的确证阳性率分别为97.92%(47/48)、81.25%(39/48)和91.67%(44/48).万泰RIBA与MP-WB之间差异有统计学意义(χ2=6.13,P＜0.05),INNO-LIA与MP-WB之间差异有统计学意义(χ2=5.48,P＜0.05),而万泰RIBA与INNO-LIA之间差异无统计学意义(χ2=1.33,P＞0.05).对于含有HIV抗体检测结果不确定样品的6套阳转血清盘,用万泰RIBA、MP-WB和INNO-LIA检测的平均阳转时间分别为0.7、13.3、3.7 d.结论 与我国目前常用的MP-WB相比,万泰RIBA和INNO-LIA可以缩短HIV抗体确证的窗口期.

Abstract：

Objective This study was to compare the performance of three HIV antibody confirmatory assay kits in confirming early HIV infection. Methods Five HIV antibody-positive plasma specimens were ten-fold serially diluted and then detected by ELISA. The above diluted specimens were detected with the following three HIV antibody coufirmatory assay kits to analyze their sensitivity, including Wantai-RIBA ( Recombinant immunoblot assay, Beijing Wantai Biological Pharmacy, China), MP-WB ( HIV Blot 2. 2 WB,MP Biomedicals Asia Pacific Pte. Ltd. ,Singapore) and INNO-LIA ( INNO-LIATM HIV Ⅰ/Ⅱ Score, Innogenetics N. V. , Belgium), respectively. These kits were further used to detect 48 ELISA-reactive specimens from 11 sets of HIV seroconversion specimens (a total of 48 sanples ) which were previously detected as HIV antibody-positive by ELISA. Results When 5 samples were diluted to 100 fold,Wantai-RIBA still can detect them positive. Among the 48 HIV antibody-positive specimens detected with ELISA,the confirmation positive rate for Wantai-RIBA, MP-WB and INNO-LIA were 97.92% (47/48),81.25 % ( 39/48 ) and 91.67% ( 44/48 ), respectively. There was statistically significant difference between the confirmatory results of Wantai-RIBA and MP-WB ( χ2 = 6. 13, P ＜ 0. 05 ), as well as between those of INNO-LIA and MP-WB ( χ2 = 5.48, P ＜ 0. 05 ); however, there was no statistically significant difference between those of Wantai-RIBA and INNO-LIA ( χ2 = 1.33, P ＞ 0. 05 ). For other six HIV seroconversion panels containing indeterminate specimens, the average seroconversion period of time for Wantai-RIBA,MP-WB and INNO-LIA were 0. 7,13.3 and 3.7 days, respectively. Conclusion Compared with MP-WB,Wantai-RIBA and INNO-LIA could reduce the window period to confirm early HIV infection.     

湖北省应城市2010年艾滋病哨点监测分析

目的 了解湖北省应城市孕产妇和性病门诊男性就诊者中艾滋病流行状况及相关行为信息.方法 按照<全国艾滋病哨点监测实施方案>要求,分别对400例孕产妇和361例性病门诊男性就诊者进行问卷调查,以及艾滋病病毒抗体、梅毒抗体和丙肝抗体检测.结果 2010年共监测2类人群761例,检出HIV抗体阳性0例;检出梅毒抗体阳性4例,检出率0.5%;检出丙肝抗体阳性1例,检出率0.1%.361例男性性传播疾病就诊者中最近一年内与暗娼和临时性伴发生性行为比率分别是14.6%和17.3%.结论 应城艾滋病感染已得到良好控制.艾滋病传播高危行为表现突出的是乱性性行为,40岁左右男性是感染艾滋病高危时期,也是预防艾滋病性病干预的重点人群.而且做好外出务工人员和流动人群艾滋病防治知识宣传教育显得尤为重要.

Abstract：

Objective To investigate the prevalence of AIDS among pregnant women and sexual transmitted disease ( STD) outpatients and their behavioral characteristics in Yingcheng. Methods According to the requirement of "The implementation scheme for sentinel surveillance of HIV infection in China" , the questionnaire surveys were conducted respectively among 400 pregnant women and 361 STD outpatients, and blood samples were taken from them for HIV, syphilis and hepatitis C virus (HCV) test. Results A total of 761 people were surveyed in 2010, among them no one were detected to be HIV positive 0% ) , 4 were detected to be infected with syphilis (0. 5% ) , 1 were detected to be infected with HCV (0. 1% ). Conclusion The infection of HIV in Yingcheng has been controlled well. The prominent high risk behavior of AIDS spreading in Yingcheng is heterosexual behavior. The men aged 40 are AIDS high-risk people and AIDS intervention focus people. Furthermore, it is very important to carry out publicity and education activities on AIDS to the immigrant laborers and the floating population.     

男男性行为者自我歧视与性行为和心理因素的关系

Objective To understand the self-discrimination experience of MSM and its relationship with sexual behavior and psychological factors.Methods By respondent-driven sampling(RDS) method, a call-for action and anonymous self-administration questionnaire investigation was carried out in Mianyang city on experience of self-discriminations, sexual partners and behaviors and depression symptom, etc.The first 12qualified people were designated as the "root" in the whole investigation from different MSM subgroups.Every "root" would get 3 recruit cards after their own investigation,then cards could be promoted to another 3 qualified people who were willing to accept questionnaires.And this process would go on till the sample size was accomplished.χ2 test,rank correlation and contingency coefficient would be applied for the statistical analysis.Results In total, 201 persons were investigated.Within the past 6 months, 59.2%(119/201) persons felt they did harm to their family or made the family down as gays ,79.6% (160/201)had to disguise their real sexual orientation in avoidance of being discriminated, 39.3% ( 79/201 ) were humiliated for having gay sex.It showed correlation between humiliation or harm to family and frequency to disco balls/night clubs( r = 0.196, χ2 = 7.95, P ＜ 0.05 ), concerts or theaters ( r = 0.201, χ2 = 8.423, P ＜0.05 ) with MSM friends, HIV health consultancy ( r = 0.231, χ2 = 11.329, P ＜ 0.05 ), experiences of one night stands ( rs = 0.183 ,μ = 2.588, P ＜ 0.05 ), detection of depression ( rs = 0.241 ,μ = 15.717, P ＜ 0.05 )and stress-related perception(rs =-0.310,μ= 23.112,P＜0.05) ,the corresponding behavior report rates of who experienced 3 -4 times were 66.7% ( 11/33 ) ,52.9% ( 18/34 ) ,41.2% ( 14/34 ), 17.6% ( 6/34 ),44.1% (15/34) ,44.7% (10/24).Statistical significance was found between the relations of humiliation for gay sex and frequency into concerts or theaters ( r = 0.195, χ2 = 7.933, P ＜ 0.05 ) with MSM friends,experiences of one night stands (rs =0.145,μ=2.051,P＜0.05),man-man anal sex (r=0.165,χ2 =10.823, P ＜ 0.05 ), numbers of female sexual partners ( r = 0.265, χ2 = 11.422, P ＜ 0.05 ), protectiveness of female sexual behavior in the past 6 months ( r =0.513 ,χ2 =7.442 ,P ＜0.05 ) ,detection of depression( rs =0.152 ,μ = 13.034, P ＜ 0.05 ) and stress-related perception ( rs = - 0.259,μ = 21.190, P ＜ 0.05 ), the corresponding behavior report rates of who experienced 3 - 4 times were 22.7% (5/22) ,9.1% (2/22),13.6% ( 3/22 ), 91.6% ( 2/22 ), 66.7% ( 2/3 ), 57.1% ( 4/7 ), 33.3% ( 19/57 ) .It has statistical significance between the relations of disguising their real sexual orientation in avoidance of being of HIV test ( r= 0.232, χ2 = 11.446, P ＜ 0.05 ), and stress-related perception ( rs = - 0.373 ,μ = 28.868,P ＜ 0.05 ).It was found that increasing of discrimination was connected to entrance into gay-welcome places,acceptance of HIV consultancy and tests, posting gay information among MSM friends and hold of many sexual partners.Meanwhile, the pressure was rising when depression was checked out.Conclusion Selfdiscrimination was prevalent among MSM ,which had brought critical influence on the individual behavior,MSM psychological health and prevalence of AIDS.     

镇江市男男性行为人群前瞻性队列研究分析

目的了解镇江市男男性行为者(men who have sex with men,MSM)HIV、梅毒螺旋体血清抗体阳转和队列保持的情况及其影响因素。方法采用前瞻性队列研究,对符合纳入标准的调查对象进行间隔6个月的随访调查,收集社会人口学和行为学信息,并采集血样进行HIV和梅毒螺旋体血清抗体检测。结果共调查MSM456名,HIV和梅毒螺旋体血清抗体阳性率分别为7.7%(95%CI:5.40%～10.51%)和10.5%(95%CI:7.86%～13.71%)。基线建立HIV血清抗体阴性队列421人,6个月随访时队列保持率为27.1%(114/421),HIV和梅毒螺旋体血清抗体阳转率分别为8.24(95%CI:7.58～8.90)/100人年和12.64(95%CI:11.76～13.51)/100人年。比较失访组和在访组基线社会人口学及行为学特征,结果发现两组在婚姻状况、户籍所在地、文化程度、最近6个月寻找性伴场所和与商业性伴发生无保护的肛交等方面差异有统计学意义。结论镇江市MSM的HIV和梅毒螺旋体血清抗体阳转率处于较高水平,针对该人群进行有效的干预已迫在眉睫。     

MSM HIV、梅毒、HSV-2新发感染及队列保持影响因素

目的 了解广西南宁市男男性行为人群(MSM)艾滋病病毒(HIV)、梅毒、单纯疱疹病毒Ⅱ型(HSV-2)新发感染率,分析队列保持的影响因素,为南宁市MSM艾滋病预防策略和措施的制定和调整提供科学依据.方法 利用滚雪球法招募研究对象,分别在基线调查后的6个月和12个月对MSM进行随访,随访内容包括问卷调查和HIV、梅毒、HSV-2检测.结果 12个月随访时,MSM人群HIV新发感染率为1.1/100人年(95％CI=0～3.3),梅毒新发感染率为6.8/100人年(95％ CI=2.1 ～11.5),HSV-2新发感染率为5.2/100人年(95％ CI=1.0～9.3);多因素logistic回归分析结果表明,6个月能随访到(OR=12.597)、在南宁市居住时间≥1年(OR =2.831)、最近6个月与女性发生过性行为(OR=5.359)是MSM队列保持的独立影响因素.结论 南宁市MSM人群HIV新发感染率低于全国其他地方报道;队列保持率较低,参加6个月随访、南宁市居住时间长、最近6个月与女性发生过性行为是此次研究队列保持的独立影响因素.     

男男性行为者自我歧视与性行为和心理因素的关系

Objective To understand the self-discrimination experience of MSM and its relationship with sexual behavior and psychological factors.Methods By respondent-driven sampling(RDS) method, a call-for action and anonymous self-administration questionnaire investigation was carried out in Mianyang city on experience of self-discriminations, sexual partners and behaviors and depression symptom, etc.The first 12qualified people were designated as the "root" in the whole investigation from different MSM subgroups.Every "root" would get 3 recruit cards after their own investigation,then cards could be promoted to another 3 qualified people who were willing to accept questionnaires.And this process would go on till the sample size was accomplished.χ2 test,rank correlation and contingency coefficient would be applied for the statistical analysis.Results In total, 201 persons were investigated.Within the past 6 months, 59.2%(119/201) persons felt they did harm to their family or made the family down as gays ,79.6% (160/201)had to disguise their real sexual orientation in avoidance of being discriminated, 39.3% ( 79/201 ) were humiliated for having gay sex.It showed correlation between humiliation or harm to family and frequency to disco balls/night clubs( r = 0.196, χ2 = 7.95, P ＜ 0.05 ), concerts or theaters ( r = 0.201, χ2 = 8.423, P ＜0.05 ) with MSM friends, HIV health consultancy ( r = 0.231, χ2 = 11.329, P ＜ 0.05 ), experiences of one night stands ( rs = 0.183 ,μ = 2.588, P ＜ 0.05 ), detection of depression ( rs = 0.241 ,μ = 15.717, P ＜ 0.05 )and stress-related perception(rs =-0.310,μ= 23.112,P＜0.05) ,the corresponding behavior report rates of who experienced 3 -4 times were 66.7% ( 11/33 ) ,52.9% ( 18/34 ) ,41.2% ( 14/34 ), 17.6% ( 6/34 ),44.1% (15/34) ,44.7% (10/24).Statistical significance was found between the relations of humiliation for gay sex and frequency into concerts or theaters ( r = 0.195, χ2 = 7.933, P ＜ 0.05 ) with MSM friends,experiences of one night stands (rs =0.145,μ=2.051,P＜0.05),man-man anal sex (r=0.165,χ2 =10.823, P ＜ 0.05 ), numbers of female sexual partners ( r = 0.265, χ2 = 11.422, P ＜ 0.05 ), protectiveness of female sexual behavior in the past 6 months ( r =0.513 ,χ2 =7.442 ,P ＜0.05 ) ,detection of depression( rs =0.152 ,μ = 13.034, P ＜ 0.05 ) and stress-related perception ( rs = - 0.259,μ = 21.190, P ＜ 0.05 ), the corresponding behavior report rates of who experienced 3 - 4 times were 22.7% (5/22) ,9.1% (2/22),13.6% ( 3/22 ), 91.6% ( 2/22 ), 66.7% ( 2/3 ), 57.1% ( 4/7 ), 33.3% ( 19/57 ) .It has statistical significance between the relations of disguising their real sexual orientation in avoidance of being of HIV test ( r= 0.232, χ2 = 11.446, P ＜ 0.05 ), and stress-related perception ( rs = - 0.373 ,μ = 28.868,P ＜ 0.05 ).It was found that increasing of discrimination was connected to entrance into gay-welcome places,acceptance of HIV consultancy and tests, posting gay information among MSM friends and hold of many sexual partners.Meanwhile, the pressure was rising when depression was checked out.Conclusion Selfdiscrimination was prevalent among MSM ,which had brought critical influence on the individual behavior,MSM psychological health and prevalence of AIDS.     

北京市男男性行为者行为因素和心理状态与HIV感染关系的研究

目的 了解北京市男男性行为者(MSM)中HIV感染情况及其影响因素.方法 于2008年3-6月,在北京市招募MSM进行问卷调查,了解其社会人口学和行为学特征,并采集血样进行HIV抗体、梅毒抗体、HBsAg和HCV抗体检测.采用X~2检验和logistic回归模型对HIV感染的影响因素进行分析.结果共有550名符合纳入标准的MSM参加本次调查,HIV感染率为4.5%(25/550).多因素logistic回归分析显示,近1个月与临时男性性伴无保护性肛交(X~2=11.381,P=0.001)、近3个月同性性行为后直肠冲洗(X~2=5.326,P=0.021)、近1个月感到悲伤(X~2=8.809,P=0.003)与MSM感染HIV的关系有统计学意义.结论 在加强安全性行为预防干预的同时需采取适当的心理干预措施,以控制HIV在该人群中的传播.     

男男性行为人群直肠冲洗行为状况及相关因素

  目的  了解男男性行为人群(men who have sex with men, MSM)直肠冲洗行为状况及相关因素,为制定针对性干预措施提供依据。  方法  2020年5月1日―2020年7月10日,在江苏省无锡市采用滚雪球抽样的方法,选取KTV、浴室、公园、酒吧等场所招募400名MSM研究对象,开展横断面调查。通过调查问卷收集研究对象的社会人口学信息、行为学信息、物质滥用史、性病史和直肠冲洗行为等内容,并采集调查对象静脉血进行HIV抗体检测。采用χ2检验和多因素Logistic回归分析模型分析MSM直肠冲洗行为的相关因素。  结果  共调查MSM400人,最近6个月发生性行为时进行直肠冲洗的占比51.3%,其中只在性行为前进行直肠冲洗的占比57.6%,只在性行为后进行直肠冲洗的占比14.6%,性行为前后均进行直肠冲洗的占比27.8%。多因素分析结果显示,月均收入>5 000元(OR=2.18, 95% CI: 1.36~3.51, P=0.001)、同性恋(OR=19.35, 95% CI: 4.01~93.38, P＜0.001)、双性恋(OR=10.31, 95% CI: 2.12~50.14, P=0.004)、最近6个月肛交时为被插入方(OR=8.96, 95% CI: 4.14~19.40, P＜0.001)、最近6个月肛交时为插入方和被插入方均有(OR=10.71, 95% CI: 4.80~23.89, P＜0.001)、物质滥用史(OR=3.20, 95% CI: 1.60~6.42, P=0.001)、性病史(OR=2.17, 95% CI: 1.30~3.63, P=0.003)、HIV检测阳性(OR=3.60, 95% CI: 1.14~11.36, P=0.029)是影响MSM直肠冲洗的相关因素。  结论  MSM发生性行为时进行直肠冲洗较普遍,且与HIV感染有关,迫切需要加强对该人群的健康教育和行为干预,以降低该人群感染HIV的风险。     

北京市男男性行为人群HIV和梅毒本底感染及新发感染调查研究

目的了解北京市男男性行为者（MSM）人类免疫缺陷病毒（HIV）和梅毒的感染情况与影响因素。方法2011年7月～2011年12月在北京招募MSM,进行本底调查,符合队列纳入标准者第3和6个月随访调查;使用平板电脑一对一问卷调查;快速检测试剂检测HIV和梅毒螺旋体抗体;统计分析使用SAS9．2统计软件包,影响因素分析单因素采用Х^2检验或Fisher确切概率法,P〈o．05的变量纳入多因素logistic回归模型分析。结果本底共招募500名MSM／HIV和梅毒感染率分别为5．60％（28／500）和26．40％（132／500）;多因素logistic回归分析显示：与HIV感染有统计学意义的因素有：最近一年未做过HIV抗体检测或不知晓检测结果（OR=2．57,95％CI：1．16～5．68）、第一次与男性发生性行为年龄≤18岁（OR=2．45,95％CI：1．07～5．62）、最近3个月发生过肛交的男性人数〉3人（OR=2．83,95％CI：1．25～6．42）;梅毒感染的独立影响因素为年龄〉30岁（OR=1．68,95％CI：1．13～2．52）、最近3个月发生过肛交的男性人数〉3人（OR=1．83,95％CI：1．15～2．92）。395名MSM进入队列,6个月随访队列保持率为88．10％（348／395）,HIV和梅毒螺旋体血清抗体阳转率分别为5．36／100人年（95%CI：2．19～8．53）和8．13／100人年（95％CI=3．53～12．73）。结论北京市MSM人群HIV／梅毒感染率及新发感染率均维持在较高水平,需要对MSM细分,以提供更有针对性的宣教及行为干预;MSM知晓检测结果与接受检测同样重要,可尝试在HIV检测咨询机构推广HIV快速检测试剂以提高检测结果知晓率。     

2010年镇江市男男性行为者队列基线调查

目的了解江苏省镇江市男男性行为者(men who have sex with men,MSM)艾滋病高危行为特征、感染情况及其影响因素。方法采用分类滚雪球抽样的方法于2010年2—9月,在镇江市范围内招募MSM进行问卷调查,了解其社会人口学及艾滋病高危行为特征,并采集血样进行人类免疫缺陷病毒(HIV)抗体、梅毒抗体、丙型肝炎病毒(HCV)抗体的检测。结果共调查456名MSM,77.0%最近6个月发生过同性口交性行为,其中61.0%有多个同性口交性伴;87.1%最近6个月发生过同性肛交性行为,其中55.3%有多个同性肛交性伴,14.9%最近1周发生过多次同性肛交性行为;11.3%最近6个月与同性发生过商业性行为,34.9%与异性发生过性行为;最近6个月与同性发生口交性行为时坚持使用安全套的比例为16.0%,肛交时坚持使用安全套的比例是40.3%,与同性发生商业性行为时坚持使用安全套的比例是40.0%,与异性发生性行为时坚持使用安全套的比例为26.4%。456名调查者均采集血样进行了血清学检测,初筛HIV阳性人数40人,确证HIV阳性人数35人,阳性率为7.3%(95%CI 5.40%～10.51%);确证梅毒抗体阳性人数为48人,阳性率为10.5%(95%CI7.86%～13.71%);确证HCV抗体阳性人数为2人,阳性率为0.4%(95%CI0.05%～1.58%);确证HIV抗体与梅毒抗体合并阳性人数为4人,合并阳性率为0.9%(95%CI 0.24%～2.23%)。在多因素logistic回归模型中,月收入为1 000～3 000元(OR=0.40,95%CI 0.18～0.87)与HIV感染的关系具有统计学意义。结论镇江市MSM中无保护性性行为较为普遍,HIV和梅毒感染率较高,应在该人群中加强包括艾滋病宣传和安全套推广在内的艾滋病干预措施,控制艾滋病等性传播疾病的流行。     

江苏省男男性行为者HIV新发感染状况及影响因素研究

目的了解江苏省男男性行为者（menwhohavesexwithmen,MSM）HIV新发感染状况及影响因素。方法2011年在江苏省8个地级市招募MSM,并进行问卷调查及实验室检测,应用BEDHIV一1IgG捕获酶免疫（BED-CEIA）法检出其中的新发感染者,以HIV阴性MSM为对照,采用多因素Logistic回归模型分析HIV新发感染的影响因素。结果共招募2432名MSM,HIV新发感染率为4．67％（95％CI：3．44％～5．89％）,HIV阴性和新发感染者之间在户籍省、文化程度、最近6个月是否与同性发生肛交、最近1次同性肛交是否使用安全套、最近6个月同性肛交安全套使用率及是否正在感染梅毒等变量上差异有统计学意义（均有P〈0．05）,多因素分析外省籍、文化程度低、最近1次同性肛交未使用安全套及正在感染梅毒是MSM人群HIV新发感染的主要危险因素。结论江苏省MSM人群中HIV新发感染率较高,提示HIV在该人群中正快速传播,必须加大防控力度;影响新发感染的主要因素仍为无保护性肛交及正在感染梅毒等。     

江苏省男男性行为人群HIV和梅毒感染状况及影响因素研究

目的 了解江苏省男男性行为人群（men who have sex with men,MSM）人类免疫缺陷病毒（human immunodeficiency virus,HIV）和梅毒感染状况及影响因素。方法 2015年在江苏省8个地级市招募MSM,并进行问卷调查及实验室检测,采用多因素Logistic回归模型分析HIV和梅毒感染的影响因素。结果 2 451名MSM的HIV感染率为10.3%,梅毒现症感染率为8.3%。多因素分析结果显示:40岁及以上、网络招募、最近6个月发生无保护性肛交（unprotected anal intercourse,UAI）、最近一年未接受过HIV检测及正在感染梅毒是MSM人群感染HIV的主要危险因素（均有P<0.05）;25岁及以上、初中及以下文化程度、场所招募及最近6个月发生UAI是MSM人群感染梅毒的主要危险因素（均有P<0.05）。结论 江苏省MSM人群HIV感染持续呈高水平状况,梅毒现症感染得到控制。促进安全套使用和HIV/梅毒检测应持续成为MSM人群性病艾滋病防治的重要工作。     

淮南市男男性行为者艾滋病相关高危行为及影响因素分析

目的了解男男性行为者(MSM)高危行为特征及其影响因素,为制定艾滋病防治措施提供参考依据。方法采用"滚雪球"方法在淮南市招募279名MSM为研究对象,通过问卷收集人口学、艾滋病知识、高危行为及干预服务接受情况等,对数据进行单因素及多因素logistic回归分析。结果 279名调查对象绝大部分为青壮年,平均年龄28岁,未婚居多、文化程度以高中及以上为主,AIDS知识知晓率为89.90%。最近6个月,应答者中100%的调查对象发生过同性肛交,7.72%发生过同性商业性行为,31.05%MSM曾经和异性发生性接触;过去6个月同性非商业性无保护肛交的发生率为62.36%,同性无保护商业性性行为发生率为38.10%,与异性发生无保护性行为发生率为83.53%。多因素logistic回归分析发现,来自县城的招募对象、最近一周同性肛交多于1次、最近六个月有异性性行为、最近一年患过性病、高艾滋病知识得分、最近一年检测过HIV与MSM最近6个月同性肛交安全套坚持使用率的关系有统计学意义。结论淮南市MSM人群艾滋病相关的高危行为普遍存在,亟需采取针对性的干预措施。     

2011-2015年芜湖市男男性行为人群安全套使用状况及影响因素分析

目的 了解2011-2015年芜湖市男男性行为人群（men who have sex with men,MSM）安全套使用情况及其影响因素,为当地制订该人群的艾滋病防治措施提供依据。方法 利用《全国艾滋病哨点监测方案》的问卷,在2011-2015年哨点监测期内对约400例MSM进行问卷调查,收集有关艾滋病知识、高危行为等资料,并采集血液进行艾滋病、梅毒、丙肝检测。结果 5年共调查MSM 2 037例。调查对象中最近半年发生肛交性行为安全套每次使用率分别是23.24%、38.13%、37.41%、47.15%和82.22%,呈现逐年上升趋势（χ_趋势2=266.778,P<0.001）;多因素Logistic回归分析结果显示最近半年发生同性商业性行为、与女性发生性行为、最近一年诊断过性病的调查对象最近半年每次肛交性行为坚持使用安全套比例较低;血清学检测结果显示调查对象艾滋病、梅毒和丙肝检测阳性率分别是5.84%、12.37%和0.69%,5年的艾滋病阳性率分别是4.36%、3.36%、6.48%、6.48%和8.64%。结论 芜湖市MSM安全套使用率有所提升,但仍然不高;艾滋病、梅毒感染率还在逐年上升,应继续加强该人群针对性宣传教育和行为干预工作。     

大连市男男性行为人群艾滋病危险行为调查

目的了解辽宁省大连市男男性行为人群(MSM)行为学特征及艾滋病病毒(HIV)、丙型肝炎(HCV)和梅毒感染率,探索HIV感染的影响因素。方法采用定向抽样方法招募MSM,进行面对面的问卷调查,并采血样进行HIV、梅毒和HCV检测。结果共招募932名MSM,HIV抗体阳性率3.43%(32/932),梅毒血清学阳性率12.12%(113/932),HCV抗体阳性率1.07%(10/932);最近6个月,88.73%(827/932)的调查对象曾经与男性发生过肛交;其中每次使用安全套的占52.18%;多因素Logistic回归模型提示,受教育程度低、外地户籍、最近6个月为男性提供商业性服务的男性、梅毒抗体阳性的MSM其HIV感染的风险高;最近1年接受过HIV抗体检测是HIV感染的保护因素。结论大连市MSM HIV感染率高,高危行为普遍存在。     

805例男男性行为者HIV感染及其影响因素分析

目的了解内蒙古部分男男性行为人群（MSM）艾滋病病毒（HIV）感染率及其影响因素。方法采用分类滚雪球抽样,在MSM聚集的酒吧、浴池、公园、公厕等地点,在知情同意下由经过专业培训的调查员进行的匿名问卷调查,并抽取静脉血检测HIV、梅毒,对影响HIV感染的相关因素进行分析。结果调查了805名MSM,艾滋病知晓率93.17%,不同调查地点的MSM艾滋病防治知识知晓率差异有统计学意义;98.76%的调查对象近6个月报告有过肛交性行为;近6个月与同性肛交安全套坚持使用率55.53%,HIV感染率3.73%,梅毒感染率17.14%。结论 MSM人群中无保护性性行为的比例高,梅毒感染率高,可能促进艾滋病在MSM人群中的快速蔓延,应加强对该人群艾滋病性病知识的宣传教育的同时强化行为干预,有效控制HIV的进一步传播。