前列炎消片治疗前列腺炎的实验研究

目的观察前列炎消片对非细菌性慢性前列腺炎模型中炎症反应的作用,为进一步的开发和应用提供药理学依据。方法SD大鼠随机分为正常对照组、模型对照组、阳性对照组（前列泰片组）及前列炎消片低（0．46g·k）、中（0．92g·kg）、高剂量组（1．84g·kg）,每组10只。分别于前列腺注入角叉菜胶生理盐水溶液和消痔灵注射液,制作大鼠非细菌性前列腺炎模型,观察测定前列腺液中白细胞数和卵磷脂小体密度、前列腺重量、前列腺指数。结果前列炎消片对角叉菜胶致大鼠急性非细菌性前列腺炎有显著抑制作用,明显减少前列腺液中自细胞数,增加卵磷脂小体密度,减轻前列腺纤维组织增生及前列腺脏器系数的增重;对消痔灵致大鼠慢性非细菌性前列腺炎亦有明显的抑制作用,减轻前列腺组织中炎细胞浸润、组织水肿和纤维组织增生及前列腺脏器系数的增重。结论前列炎消片具有抑制大鼠非细菌性急、慢性前列腺炎炎症反应的作用。     

An experimental study on drugs for improving blood circulation and removing blood stasis in treating mild chronic hepatic damage.

Large and small doses of drugs for improving blood circulation and removing blood stasis were used in model rats to treat mild chronic hepatic damage induced by carbon tetrachloride (CCl4). The results show that large dose of Dang Gui ([symbol: see text] Radix Angelicae Sinensis) and Dan Shen ([symbol: see text] Radix Salviae Miltiorrhizae) (drugs for regulating blood flow) and small dose of Yu Jin ([symbol: see text] Radix Curcumae) and Niu Xi ([symbol: see text] Radix Achyranthis Bidentatae) (drugs for activating blood flow) can significantly elevate the activity of SOD (P < 0.05) and/or lower the T/K ratio, markedly reduce the MDA content (P < 0.05 or P < 0.01) and significantly decrease the activities of ALT and AST (P < 0.05 or P < 0.01), demonstrating that these drugs are effective in combating oxygen free radicals (OFR) in chronic liver damage. On the contrary, large dose of Tu Bie Chong ([symbol: see text] Eupolyphaga seu Steleophaga) and E Zhu ([symbol: see text] Rhizoma Curcumae) (drugs for removing blood stasis) tend to increase the ALT and AST (P < 0.05) activities. The results suggest that the synergism of elevation of the SOD activity and reduction of T/K ratio contributes to the action of drugs for improving blood circulation and removing blood stasis in combating the liver damage induced by CCl4.     

A study of Helicobacterium pylori and prevention and treatment of chronic atrophic gastritis.

The rate of detection of helicobacterium pylori (HP) in chronic atrophic gastritis (CAG) is 67%, HP being a slightly aerobic Gram-negative bacterium. Some drugs of traditional Chinese medicine (TCM) for clearing away heat and for removing blood stasis have significant effect on inhibition of HP. The drugs in both the recipe for nourishing yin, clearing away heat and invigorating blood circulation and the recipe for clearing away heat and invigorating blood circulation have inhibitory action on HP in vitro. All patients with CAG have symptoms of damp-heat and blood stasis. Radix et Rhizoma Rhei and Rhizoma Coptidis Decoction for Purging Stomach-Fire ([symbol: see text]) as the basic recipe and "Huo Wei" ([symbol: see text]) No. 2 recipe as the supplementary have good inhibitory effect on HP in inhibition tests. The results show several forms of the medicine all resulted in significant good therapeutic effect.     

三仁萆薢饮治疗慢性前列腺炎临床观察

目的：观察三仁萆薢饮治疗慢性前列腺炎的疗效。方法：与前列舒通胶囊对照观察验方三仁萆薢饮对湿热瘀阻型慢性前列腺炎患者NIH-CPSI评分、前列腺指诊情况和前列腺液中WBC数量的综合影响。结果：三仁萆薢饮组治愈率53.3%,总有效率90%;前列舒通胶囊组治愈率35%,总有效率75%。结论：三仁萆薢饮对湿热瘀阻型慢性前列腺炎有较好疗效。     

Clinical Observation in 31 Cases of Chronic Bronchitis at Remission Stage Treated with Bufei Keli

To observe the therapeutic effects of a Chinese drug Bufei Keli (补肺颗粒 granules for invigorating thelung) in the treatment of chronic bronchitis at remission stage, 62 cases were randomly divided into aThe results turned out to be that the short-term clinically controlled and markedly effective rate was77.42% and the long-term relapse-resisting markedly effective rate was 74.2% in the treatment group,which were obviously higher than 45.16% and 38.71% respectively in the control group (P＜0.05). And theincrease in contents of SOD and CD3 and the decrease in LPO content in the treatment group were alsobigger than that in the control group (P＜0.01). It is therefore concluded that Bufei Keli can improve qideficiency syndrome and raise the immunity of patients with chronic bronchitis, hence its effect ofresisting relapse of chronic bronchitis.     

TCM Treatment of Bronchial Asthma

Xuan Fei Ding Chuan Wan(宣肺定喘丸 pills for facilitating the flow of the lung-qi to relieve asthma)and Xiao Chuan Gu Ben Wan (哮喘固本丸 pills for treating asthma by consolidating the origin)wereused for treatment of bronchial asthma.The cure rate in the treated group(n=600)was 81.33%,significantly higher(P<0.01)than that in the control group(n=164,with a cure rate of 9.76%).     

One hundred and seven middle-aged and senile cases of coronary heart disease with ventricular premature beat treated by qing xin an shen fang.

The therapeutic principle of clearing away the heart-heat to induce tranquilization was adopted in 107 middle-aged and senile patients with ventricular premature beat of coronary heart disease on the basis of pathogenic features of phlegm, heat, blood stasis and deficiency in this condition. Qing Xin An Shen Fang ([symbol: see text] a formula for clearing away the heart-heat to induce tranquilization) was used in the treatment group and compared with mexiletine and Fu Fang Dan Shen Tablets ([symbol: see text] Compound Salvia Tablets) used in the control group. The results turned to be that the markedly effective rate was 85.1% and the total effective rate 96.3% in the treated group, better than that in the control group, with the former having a good antihypertensive and antihyperlipemic effect and an effect of improving microcirculation and clinical symptoms.     

Prof.Sheng Canruo’s Experience in Acupuncture Treatment of Throat Diseases with Yan Si Xue

Yan Si Xue(咽四穴)refer to four points in the throat summarized by Prof.Sheng Canruo in his long-year clinical experience based on the combination of TCM theory and the knowledge of modernmedical anatomy.By taking “Yan Si Xue” as main points,and other differential adjunct points,Prof.Sheng has obtained satisfactory therapeutic results in treating various throat diseases such ashoarseness,paralysis of vocal cord,dysphonia after radiotherapy on throat tumor,vocal nodules,disorder of the glossopharyngeal nerve,hysteric aphasia,and acute or chronic laryngopharyngitis.     

Effects of Qianlie''''an(前列安)Suppository in Patients with Chronic prostatitis Syndrome:A Randomized Open-Labelled Prospective and Controlled Trial

Objective:To evaluate the clinical efficacy of Qianllie’an(前列安,QLA)suppository via a-nal route administration in treating chronic prostatitis syndrome.Methods:A randomized open-labelledprospective controlled trial was carried out.The total of 120 patients with chronic prostatitis syndromewere randomly divided into 2 groups:60 patients in the treated group who were treated with QLA supposi-tory combined with ofloxacin,and the other 60 patients in the control group who were given ofloxacin a-lone.The efficacy was evaluated by WBC Count in the expressed prostatic secretion(EPS)and the ChronicProstatitis Symptom Index(CPSI)made by the National Institute of Health(NIH).The clinical effectsWere also observed in a 4-week follow-up.Results:All but six cases completed the trial and the follow-up.It showed that in the treated group recovery rate was 17.2％,markedly effective rate 34.5％,effectiverate 32.8％,total markedly effective rate 51.7％,and total effective rate 84.5％,all of which were supe-rior to th     

Effects of Qianlie’an suppository in patients with chronic prostatitis syndrome: A randomized open-labelled prospective and controlled trial

Objective: To evaluate the clinical efficacy of Qianlie’an (QLA) suppository via anal route administration in treating chronic prostatitis syndrome.Methods: A randomized open-labelled prospective controlled trial was carried out. The total of 120 patients with chronic prostatitis syndrome were randomly divided into 2 groups: 60 patients in the treated group who were treated with QLA suppository combined with ofloxacin, and the other 60 patients in the control group who were given ofloxacin alone. The efficacy was evaluated by WBC count in the expressed prostatic secretion (EPS) and the Chronic Prostatitis Symptom Index (CPSI) made by the National Institute of Health (NIH). The clinical effects were also observed in a 4-week follow-up.Results: All but six cases completed the trial and the follow-up. It showed that in the treated group recovery rate was 17. 2%, markedly effective rate 34. 5%, effective rate 32. 8%, total markedly effective rate 51. 7%, and total effective rate 84. 5%, all of which were superior to those in the control group (total markedly effective rate 32.1% and total effective rate 66.1%, respectively),P < 0.01.Conclusion: Administration of QLA suppository via anal route combined with oral antibiotics is an effective therapy for chronic prostatitis syndrome. It can relieve the symptoms of chronic prostatitis syndrome markedly and rapidly. It is a new choice for treatment of the disease.     

Clinical Observation on the Method of Supplementing Qi, Clearing away Heat and Promoting Blood Circulation for Treating 53 Cases of Gastritis Related to Pyrolic Helicobacterium

According to the clinical experience of professor Shan Zhaowei (单兆伟), the author has successfully developed Qingyou Yangwei Capsule (清幽养胃胶囊capsules for eliminating pyrolic Helicobacterium and nourishing the stomach) for treating the gastritis. Clinical research has shown that the capsule has a good curative effect on chronic gastritis related to pyrolic Helicobacterium. Among the 53 cases in the treatment group, clinical observation showed cure in 6 cases, obvious effect in 18 cases, effect in 24 cases, no effect on 5 cases, with a total effective rate of 90.5%. Of the 50 cases in the control group, cure was found in 5 cases, obvious effect in 13 cases, effect in 20 cases, no effect in 12 cases, the total effective rate being 76%. The total effective rate in the treatment group was higher than that in the control group. The rate of eliminating pyrolic Helicobacterium in the treatment group was 66.04%, similar to that in the control group. In a follow-up visit 6 months later, the recurrence rate in the treatment group was 13.33%, obviously lower than that of 41.66% in the control group.     

Clinical Observation in 86 Cases of Acne Vulgaris Treated with Compound Oldenlandis Mixture

86 cases of acne vulgaris were treated with Fu Fang She She Cao He Ji (复方蛇舌草合剂 CompoundPrepared from Chinese Angelica and Flavescent Sophora Root) as the controls, to observe the therapeuticeffect of the former. The results showed that the cure plus markedly effective rate was 73.26% in thetreatment group, and 47.06% in the control group, with a significant difference in the cure plus markedlyeffective rate between the two groups (P＜0.01), and also in the total effective rate between the two groupssignificant (P＜0.05). It may be concluded that the Compound Oldenlandis Mixture is a better agent for theillness.     

Clinical study on treatment of chronic renal failure with shenshuailing.

The therapeutic effects of Shenshuailing Kou Fu Ye (SKFY [symbol: see text], the Oral Liquid for Renal Failure) and Shenshuailing Guan Chang Ye (SGCY [symbol: see text], the Enema for Renal Failure) were evaluated in treatment of chronic renal failure, with coateg aldehyde oxystarch as the controls. The changes in the clinical symptoms, serum creatinine, blood urea nitrogen and creatinine clearance rate were observed. The total effective rate in the former was 90.46%, and the latter 60.43%.     

前列安栓治疗慢性前列腺炎临床分析

目的 评估前列安栓治疗慢性前列腺炎的临床效果.方法 将120例慢性前列腺炎患者随机分成前列安栓 抗生素组和单用抗生素对照组,前列安栓组在应用抗生素同时每日用一粒前列安栓于晚间便后塞入肛门3-5 cm;抗生素组单用广谱抗生素药物,对两组疗效进行分析评估.结果 前列安栓组总有效率达77.1%,抗生素对照组有效率42%,差异有统计学意义.结论 前列安栓治疗慢性前列腺炎临床效果满意,是治疗慢性前列腺炎有效药物之一,值得推广.     

Treatment of the Localized Neurodermatitis by Plum-blossom Needle Tapping and with the Modified Yangxue Dingfeng Tang——A Clinical Observation of 47 Cases

Since 1993, the authors have successfully treated 47 cases of the localized neurodermatitis by plum-blossom needle tapping and with the modified Yangxue Dingfeng Tang, with quite good therapeutic results reported as follows. Clinical Data The 141 patients…     

The principle and technique of using Chinese drugs in the treatment of hypertension.

Differential use of Chinese and western drugs, and combination of traditional theory of materia medica with the results of modern pharmacological research can be regarded as a general principle in the treatment of a disease, while combination of lowering blood pressure with preventing and treating complications is a specific method in the treatment of hypertension. As to the use of drugs based on differentiation of diseases and/or symptoms, drugs which have the action of relieving symptoms but also reducing blood pressure should be used as the first choice. For those drugs which have the action of relieving symptoms but can not lower blood pressure should not be used or should be used as less as possible. Drugs with action of raising blood pressure are contraindicated. When patients have the symptoms of hyperactivity of yang resulting from yin deficiency, Huang Bo ([symbol: see text] Cortex Phellodendri) and Zhi Mu ([symbol: see text] Rhizoma Anemarrhenae) are used together to enhance the effects of both nourishing yin to reduce pathogenic fire, and reducing blood pressure. This practice conforms to the TCM theory and also to the modern pharmacological research.     

水蛭通栓治疗前列腺炎的实验研究

目的：探讨水蛭通栓抗前列腺炎的作用。方法：应用甲醛一巴豆油引起大鼠慢性前列腺炎模型，观察水蛭通栓对慢性前列腺炎大鼠前列腺病理组织学和前列腺指数的影响。结果：水蛭通栓能降低慢性前列腺炎大鼠的前列腺指数，改善前列腺病理组织学的改变。结论：水蛭通栓具有抗慢性前列腺炎作用。