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1.
D Poddar G H Maude M J Plant H Scorer G R Serjeant 《British journal of obstetrics and gynaecology》1986,93(7):727-732
The outcome of 664 pregnancies in 297 Jamaican women with homozygous sickle cell (SS) disease over the period 1959-1984 was reviewed. Overall, the spontaneous abortion rate was 118 per 1000 pregnancies, the stillbirth rate 128 per 1000 births, and perinatal mortality 171 per 1000 births. There was a striking secular increase in both spontaneous abortions and stillbirths which was accounted for, in part, by a trend for abortions to increase with maternal age up to the age of 30 years, a greater proportion of patients in the high-risk 25-29 year age group occurring in the 1980-1984 period. Another factor contributing to the poor obstetric performance in the 1980-1984 period was probably an increased survival and pregnancy rate in high-risk patients. Seven women had pregnancy-related deaths giving a pregnancy mortality rate of 1.1%. 相似文献
2.
D. PODDAR Lecturer G. H. MAUDE Statistician M. J. PLANT Medical Student H. SCORER Medical Student G. R. SERJEANT Director 《BJOG : an international journal of obstetrics and gynaecology》1986,93(7):727-732
Summary. The outcome of 664 pregnancies in 297 Jamaican women with homozygous sickle cell (SS) disease over the period 1959–1984 was reviewed. Overall, the spontaneous abortion rate was 118 per 1000 pregnancies, the stillbirth rate 128 per 1000 births, and perinatal mortality 171 per 1000 births. There was a striking secular increase in both spontaneous abortions and stillbirths which was accounted for, in part, by a trend for abortions to increase with maternal age up to the age of 30 years, a greater proportion of patients in the high-risk 25–29 year age group occurring in the 1980–1984 period. Another factor contributing to the poor obstetric performance in the 1980–1984 period was probably an increased survival and pregnancy rate in high-risk patients. Seven women had pregnancy-related deaths giving a pregnancy mortality rate of 1.1%. 相似文献
3.
D. PODDAR Lecturer G. H. MAUDE Statistician M. J. PLANT Medical Student H. SCORER Medical Student G. R. SERJEANT Director 《BJOG : an international journal of obstetrics and gynaecology》1986,93(6):727-732
Summary. The outcome of 664 pregnancies in 297 Jamaican women with homozygous sickle cell (SS) disease over the period 1959–1984 was reviewed. Overall, the spontaneous abortion rate was 118 per 1000 pregnancies, the stillbirth rate 128 per 1000 births, and perinatal mortality 171 per 1000 births. There was a striking secular increase in both spontaneous abortions and stillbirths which was accounted for, in part, by a trend for abortions to increase with maternal age up to the age of 30 years, a greater proportion of patients in the high-risk 25–29 year age group occurring in the 1980–1984 period. Another factor contributing to the poor obstetric performance in the 1980–1984 period was probably an increased survival and pregnancy rate in high-risk patients. Seven women had pregnancy-related deaths giving a pregnancy mortality rate of 1·1%. 相似文献
4.
Affaf M. El-Shafei FRCOG Jagjeevan Kaur Dhaliwal FRCOG DA Amarjeet Kaur Sandhu MD FRCOG Mona Rashid Al-Sharqi MBBCh 《The Australian & New Zealand journal of obstetrics & gynaecology》1995,35(4):405-408
EDITORIAL COMMENT": These authors have previously reported the importance of sickle cell anaemia as a cause of maternal mortality in Bahrain (A). We have accepted this paper for publication although sickle cell anaemia is rare in Australia so that our readers can see the lesson learnt from this very large experience of 571 cases, namely that prophylactic blood transfusion is not indicated unless the haemoglobin value falls below 6 g/dL. We presume that all of these patients would require blood to be cross-matched and available at delivery in case of postpartum haemorrhage.
Summary: In order to assess the value of prophylactic blood transfusion in the management of pregnant patients with sickle cell disease, a study was conducted on 571 sickle cell disease pregnancies. These patients were divided into 2 groups, one with prophylactic transfusion and the other with restricted transfusion. In spite of the reduction in the incidence of blood transfusion the rate of preterm labour, intrauterine growth retardation, perinatal mortality and maternal mortality were similar in both groups.
A restricted blood transfusion policy can be safely followed without compromising fetal or maternal well-being with an additional benefit of reducing the incidence of transfusion related crises and other complications. 相似文献
Summary: In order to assess the value of prophylactic blood transfusion in the management of pregnant patients with sickle cell disease, a study was conducted on 571 sickle cell disease pregnancies. These patients were divided into 2 groups, one with prophylactic transfusion and the other with restricted transfusion. In spite of the reduction in the incidence of blood transfusion the rate of preterm labour, intrauterine growth retardation, perinatal mortality and maternal mortality were similar in both groups.
A restricted blood transfusion policy can be safely followed without compromising fetal or maternal well-being with an additional benefit of reducing the incidence of transfusion related crises and other complications. 相似文献
5.
K E Rajab A A Issa A M Mohammed A A Ajami 《International journal of gynaecology and obstetrics》2006,93(2):171-175
OBJECTIVE: To determine the morbidity and outcome of pregnancies complicated by homozygous sickle cell disease (SCD) in Bahrain. METHODS: A controlled study was conducted of all the pregnancies of women with SCD who were delivered at Salmaniya Medical Complex and affiliate hospitals in Bahrain between January 1, 1998, and December 31, 2002. RESULTS: There were 351 pregnancies with SCD, giving an incidence of 0.67%. The mean+/-S.D. age of women with SCD was 28.8+/-5.7 years. These women, who were mostly from Shia villages, had more spontaneous abortions than the 351 controls (32% and 12%, respectively). Compared with the control group, the mean+/-S.D. number of pregnancies among women with SCD was 5.0+/-1.9 vs. 5.7+/-3.1; birth weight, 2,965+/-540 g vs. 3,457+/-497 g; rate of preterm deliveries, 25.9% vs. 12%; incidence of intrauterine growth restriction, 10% to 13% vs. 4% to 7%; Apgar scores at 1 and 10 min, 8.1+/-0.8 and 8.8+/-0.8; and cesarean section rate, 19.0% vs. 12.7%. There were no differences in the rates of pre-eclampsia, antepartum and postpartum hemorrhage, or stillbirth. There were 4 maternal deaths directly related to SCD complications. Hemoglobin analysis was performed in 86% of the women with SCD. Of these women, 60.6% had homozygous SCD with raised levels of fetal hemoglobin (more than 5% HbF); 9.6% had sickle cell hemoglobin with beta-thalassemia disease; and 1.4% had sickle cell hemoglobin only. Vaso-occlusive crises were the most common cause of hospital admissions during pregnancy (42.2%), while hemolytic and sequestration crises accounted for 28.0% and 0.6% of admissions. CONCLUSION: Mortality, morbidity, and perinatal loss are still considerable among women with SCD in Bahrain. To reduce mortality and morbidity, there is a need for a multidisciplinary team able to deal with pregnancy complications due to SCD. 相似文献
6.
Sun PM Wilburn W Raynor BD Jamieson D 《American journal of obstetrics and gynecology》2001,184(6):1127-1130
OBJECTIVE: We compared pregnancy outcomes among women with sickle cell disease with outcomes for African American women without the disease. STUDY DESIGN: We selected 127 deliveries in women with sickle cell disease (hemoglobin SS or hemoglobin SC) that occurred between 1980 and 1999. A control group of 129 deliveries by African American women with normal hemoglobin (hemoglobin AA) was also selected. Evaluated pregnancy outcomes included low birth weight, prematurity, intrauterine growth restriction, antepartum hospital admission, preterm labor or preterm premature rupture of membranes, postpartum infection, preeclampsia, pyelonephritis, intrauterine fetal death, perinatal mortality, and maternal mortality. RESULTS: Compared with deliveries among women with hemoglobin AA, deliveries among women with hemoglobin SS or hemoglobin SC were at increased risk for intrauterine growth restriction, antepartum hospital admission, and postpartum infection. In addition, deliveries among women with Hb SS were more likely to be complicated by low birth weight, prematurity, and preterm labor or preterm premature rupture of membranes when compared with deliveries among women with hemoglobin AA. There were no significant differences among the groups (hemoglobin SS, hemoglobin SC, and hemoglobin AA) in terms of perinatal deaths; there were no maternal deaths in the study population. CONCLUSION: Those caring for women with sickle cell disease should be aware that they are at increased risk for pregnancy complications, although overall pregnancy outcome is favorable. 相似文献
7.
SUSAN M. TUCKRegistrar J. W. W. STUDD Consultant J. M. WHITE Professor 《BJOG : an international journal of obstetrics and gynaecology》1983,90(2):112-117
Summary. The complications and outcome of 125 pregnancies in women with sickle cell disease between 1975 and 1981 are reviewed. There were no maternal deaths, but a perinatal mortality rate of 48 per 1000. The main maternal complications were sickling crises (38%), anaemia (65%), infections (61%) and severe pregnancy-induced hypertensive disease (5%). There were three patients with eclampsia. There was a 13% spontaneous preterm delivery rate, 25% of the babies were'light-for-dates', fetal distress in labour was seen in 24% and 15% were delivered by caesarean section. There was an increased incidence of involuntary infertility and spontaneous abortion. The treatment by prophylactic blood transfusions is discussed. 相似文献
8.
Thirty-four patients with abnormal hemoglobin were studied through 42 pregnancies under one obstetrician. There were 30 patients with sickle cell anemia (HbSS), two with sickle cell hemoglobin C disease (HbSC) and two with homozygous hemoglobin C disease (HbCC). There were 39 live births (including one pair of twins), and four perinatal deaths. The patients with HbSC and HbCC had five uncomplicated pregnancies and deliveries. Of the 36 pregnancies in patients with HbSS one aborted at 12 weeks. Intra-uterine growth retardation (14.3%) and pregnancy-induced hypertension (14.3%) were the most serious pregnancy complications. No patient had more than one crisis. Only one out of the 10 patients transfused needed more than two units of blood throughout pregnancy. The mean gestation at delivery was 37.5 +/- 3.2 (S.D.) weeks. The mean birth weight was 2.7 +/- 0.6 (S.D.) kg. The perinatal mortality was 114.3 per thousand live births and there was one maternal death. 相似文献
9.
Pregnancy in sickle cell disease 总被引:3,自引:0,他引:3
D R Powars M Sandhu J Niland-Weiss C Johnson S Bruce P R Manning 《Obstetrics and gynecology》1986,67(2):217-228
Risks associated with pregnancy for mothers with sickle cell disease and their infants have decreased markedly during the last decade. Among 79 women with sickle cell anemia (156 pregnancies), maternal death decreased from 4.1% before 1972 to 1.7% after 1972; their infants' fetal and perinatal death rates decreased from 52.7 to 22.7% (P less than .05), and from 33.3 to 27.3% among infants of women with sickle hemoglobin C disease. There has been a significant improvement in birth weight specific mortality and an increase in number of weeks' gestation from 34.7 to 37.4 (P less than .05). A higher percentage of sickle hemoglobin C disease mothers completed their pregnancies with no complications (43%) when compared with sickle cell anemia mothers (21%), thus identifying a subset of women for whom pregnancy does not represent an increased risk. These results are attributed to improvements in state-of-the-art medical, obstetric, and perinatal care. 相似文献
10.
OBJECTIVE: Recent studies have reported increased fetal loss and preeclampsia in women with sickle cell trait (hemoglobin [Hb] AS). There is a paucity of studies of outcomes in carriers of hemoglobin C. We examined the prevalence of hemoglobin C and S carrier status (Hb AC and Hb AS, respectively) and their effect on pregnancy outcomes. METHODS: This was a retrospective cohort study using data prospectively collected from 1991 to 2006. Perinatal and maternal outcomes for African-American women with Hb AS and Hb AC were compared with those with normal hemoglobin (Hb AA). Multivariable regression was performed by applying generalized estimating equations to account for correlation between births from the same woman. RESULTS: Among 22,096 eligible African-American women (36,897 pregnancies) with routine antenatal hemoglobin electrophoresis, 88.5% had a normal (Hb AA) pattern. Hemoglobin AS was identified in 8.2% and Hb AC in 2.4% of women. Hemoglobin SS and Hb SC each accounted for less than 0.2% and Hb CC for 0.01%. Prevalence and relative risks for adverse outcomes in 3,019 AS pregnancies (3,062 births) and 875 AC (886 births), compared with 32,724 AA pregnancies (33,213 births), were not increased. Adjusted relative risks (95% confidence intervals) for perinatal mortality and preeclampsia were 0.7 (0.5-1.0) and 1.0 (0.8-1.2), respectively, for AS and 0.7 (0.3-1.4) and 1.0 (0.6-1.3), respectively, for AC. Risks of stillbirths and pregnancy-associated hypertension were also not increased. CONCLUSION: Contrary to other recent reports, perinatal mortality and preeclampsia are not increased in carriers of sickle cell trait or hemoglobin C. LEVEL OF EVIDENCE: II. 相似文献
11.
《BJOG : an international journal of obstetrics and gynaecology》1985,92(S5):14-22
Summary. Both formal education and antenatal care had tremendous impact on the results of childbearing. In women who had never had any formal education nor received antenatal care, that is 33% of the survey population, maternal mortality was 29 per 1000 deliveries, perinatal mortality was 258 per 1000 total births and 26% of the babies weighed ≤2.50 kg. With education and antenatal care combined, as was the case in 10% of the survey population, the maternal death rate was 2.5 per 1000 deliveries, perinatal mortality rate was 30 per 1000 total births, and only 8% of the babies were of low birthweight. Among women in their thirties and beyond, the average number of previous births per woman in the illiterate group (5.4) was double that in those who had received post-secondary education and child mortality rate at 25% was three times as high. Formal education, by changing social attitudes, holds the key to improvements in maternal and perinatal health. 相似文献
12.
Wylie BR Kong J Kozak SE Marshall CJ Tong SO Thompson DM 《American journal of perinatology》2002,19(4):169-176
Reports of outcomes of pregnancy in women with type 1 diabetes have consistently found increased perinatal mortality and morbidity. The primary objective of our study was to compare the perinatal mortality rate in type 1 diabetic pregnancies with that of the general population. The secondary objective was to compare the morbidities in these groups. A series of 247 women with type 1 diabetes had 300 consecutive pregnancy outcomes analyzed over a 10-year period. They were compared with the control population from the same hospital. Perinatal mortality was 6.6/1000 (95% CI, 0-17), which was significantly lower than the control population rate of 31/1000. There was an increased incidence of morbidity including maternal hypertension, cesarean section, preterm delivery, birth injury, large for gestational age infants, admissions to neonatal intensive care, neonatal hypoglycemia, and phototherapy. Pregnancies in type 1 diabetes can be associated with a normal perinatal mortality rate although morbidity remains elevated compared with controls. 相似文献
13.
Alexis SHUB Clement WONG Belinda JENNINGS Jonathan R. SWAIN John P. NEWNHAM 《The Australian & New Zealand journal of obstetrics & gynaecology》2009,49(2):130-136
Background: Periodontal disease has been associated with increased perinatal mortality.
Aims: To examine the association between maternal periodontal disease and perinatal mortality.
Methods: We performed a retrospective and prospective matched case–control study of women with unexplained perinatal mortality at more than 20 weeks gestational age. Women were matched for socioeconomic status, smoking status and time since delivery. All women underwent a detailed periodontal examination and completed a questionnaire describing oral health symptoms. No intervention took place.
Results: Fifty-three women who had experienced a perinatal death and 111 controls completed the study. Thirty-two women were recruited retrospectively and 21 women were recruited prospectively. Twenty-three (43.4%) women who had experienced a perinatal death and 27 (24.3%) controls had periodontal disease. There were no differences in oral health behaviours or symptoms between cases and controls. Perinatal death was associated with periodontal disease (odds ratio (OR) 2.34, 95% confidence interval (CI) 1.05, 5.47). Periodontal disease was more strongly associated with perinatal mortality due to extreme prematurity (OR 3.60, 95% CI 1.20, 12.04). Multivariate analysis showed this relationship to be consistent after inclusion of higher parity, country of birth, advanced maternal age and maternal obesity in the model (OR 4.56, 95% CI 1.25, 21.27).
Conclusions: Maternal periodontal disease may contribute to perinatal mortality, especially that caused by extreme prematurity. 相似文献
Aims: To examine the association between maternal periodontal disease and perinatal mortality.
Methods: We performed a retrospective and prospective matched case–control study of women with unexplained perinatal mortality at more than 20 weeks gestational age. Women were matched for socioeconomic status, smoking status and time since delivery. All women underwent a detailed periodontal examination and completed a questionnaire describing oral health symptoms. No intervention took place.
Results: Fifty-three women who had experienced a perinatal death and 111 controls completed the study. Thirty-two women were recruited retrospectively and 21 women were recruited prospectively. Twenty-three (43.4%) women who had experienced a perinatal death and 27 (24.3%) controls had periodontal disease. There were no differences in oral health behaviours or symptoms between cases and controls. Perinatal death was associated with periodontal disease (odds ratio (OR) 2.34, 95% confidence interval (CI) 1.05, 5.47). Periodontal disease was more strongly associated with perinatal mortality due to extreme prematurity (OR 3.60, 95% CI 1.20, 12.04). Multivariate analysis showed this relationship to be consistent after inclusion of higher parity, country of birth, advanced maternal age and maternal obesity in the model (OR 4.56, 95% CI 1.25, 21.27).
Conclusions: Maternal periodontal disease may contribute to perinatal mortality, especially that caused by extreme prematurity. 相似文献
14.
《International journal of gynaecology and obstetrics》1994,45(2):109-115
OBJECTIVES: To determine levels and risk factors for perinatal mortality in Central Sudan. METHODS: Hospital and community based studies were conducted during the period 1989–1990. Of 5328 births registered in the hospital, 197 stillborns and 812 live-born infants were included in a nested case-control study. In the community, a follow-up study was conducted on 1592 midwife-assisted home deliveries. Multivariate logistic regression analysis was used to identify predictors of perinatal mortality and adjusted population attributable risks were estimated to assess the contribution of each factor. RESULTS: The perinatal mortality rate was 85.4/1000 births in the hospital population and 29.4/1000 births in the community population. The major risk factors for perinatal mortality in the hospital and the community studies were similar and modifiable. CONCLUSIONS: To lower perinatal mortality, improvements in maternal nutrition, malaria treatment and control, avoidance of agricultural pesticides during pregnancy, and adequate antenatal and intrapartum care are recommended. 相似文献
15.
Impact of a permissive abortion statute on community health care 总被引:3,自引:0,他引:3
J J Rovinsky 《Obstetrics and gynecology》1973,41(5):781-788
3542 first-trimester and 876 second-trimester abortions were performed at City Hospital Center, Elmhurst, New York, from July 1,1970 to June 30, 1972. The relatively stable, semi-closed population of women involved permitted an analysis of the effect of a permissive abortion law and practice on general health care. Tables of patient characteristics and abortion statistics over the period indicated the following: a present rate of abortion of 1009 per 1000 births; no maternal mortality; a reduction in maternal morbidity as experience with abortion techniques increased; a reduction by 44.4% of the number of deliveries without prenatal care, by 16.5% of premature deliveries, by 23.1% of immature deliveries; and a 29.2% reduction of the perinatal mortality rate. Also shown was a marked change in age distribution from the beginning of the period to the end: the incidence of abortions decreased among patients less than 20 years old by 47.1%, and among those over 35 by 46.7%. Additionally, the number of abortions among "never-married" women was reduced by 59.5%. There was a threefold increase in utilization of the antepartum clinic during the first trimester and an increase in prenatal visits. Incidence of spontaneous early abortion was reduced 52.2% and septic abortions were almost entirely eliminated. Postpartum psychosis decreased by half, the rate of voluntary sterilization doubled, and registration of new patients for family planning increased by 116%. Improvements were also seen in pregnancy testing and counseling, in cancer detection through an increase in the number of papanicolaou smears, screening for venereal disease and sickle cell trait/disease, and in the detection of medical, surgical and psychosocial diseases. Pregnancies were largely eliminated in "high-risk" obstetric patients from the childbearing population such as the very young or old, the unmarried, or the emotionally disturbed. The influence of liberalized abortion statutes was shown to have served the community not only by solving immediate health crises but also by contributing to the development of a total health care program. 相似文献
16.
Hypertensive disorders of pregnancy. 总被引:3,自引:0,他引:3
Z Zareian 《International journal of gynaecology and obstetrics》2004,87(2):194-198
OBJECTIVES: This study was undertaken to determine the prevalence of hypertensive disorders of pregnancy and evaluate their effects on the mothers and fetuses at Jahrom, a city in southern Iran. METHODS: A retrospective survey was performed on 2300 pregnant women who had referred to Shahid Motahhari Hospital of Jahrom School of Medical Sciences from 22 September 2002 to 21 September 2003. Diagnosis of hypertensive disorders of pregnancy and their probable complications were made according to medical recording files. RESULTS: Among the studied patients, 3.3% were diagnosed as having hypertensive disorders of pregnancy, of which 96% were cases of preeclampsia/eclampsia or transient hypertension. In hypertensive patients, the overall maternal mortality rate was 1.3 per 10,000 and perinatal mortality rate was 53 per 1000 births. Low birth weight neonates were observed in 20% of cases. CONCLUSION: Hypertensive disorders of pregnancy commonly complicate pregnancy and have great influences on maternal and neonatal morbidity and mortality rates and more attention and precision is needed to evaluate the pregnant women for detecting and preventing the complications. 相似文献
17.
F G Cunningham J A Pritchard R Mason G Chase 《American journal of obstetrics and gynecology》1979,135(7):994-1003
Prophylactic transfusions of normal donor red cells were administered during 37 pregnancies to women with sickle cell anemia, sickle cell-hemoglobin C disease, or sickle cell-beta thalassemia disease. Once the diagnosis was confirmed, the transfusions were administered intermittently throughout the rest of the pregnancy in such amounts and at such frequencies that no more than 60% of the circulating red cells contained hemoglobin S and the hematocrit was above 25. The maternal mortality rate was zero and maternal morbidity as the consequence of the sickle cell hemoglobinopathy was minimal. The perinatal mortality rate was appreciably reduced when compared to that previously observed without prophylactic transfusions but perinatal morbidity was still excessive. Evidence that the intrauterine environment was compromised, in spite of the transfusions consisted of an increased frequency of growth-retarded fetuses, of meconium staining of amnionic fluid, and of ominous decelerations of fetal heart rate. Morbidity from the transfusions was troublesome. Nonetheless, it is concluded tentatively that both the mother with a sickle cell hemoglobinopathy and her fetus are likely to benefit from prophylactic transfusions of normal donor red cells administered during one pregnancy according to the protocol employed in this study. 相似文献
18.
OBJECTIVE: To review the incidence, associated factors, methods of diagnosis, and maternal and perinatal morbidity and mortality associated with uterine rupture in one Canadian province. METHODS: Using a perinatal database, all cases of uterine rupture in the province of Nova Scotia for the 10-year period 1988-1997 were identified and the maternal and perinatal mortality and morbidity reviewed in detail. RESULTS: Over the 10 years, there were 114,933 deliveries with 39 cases of uterine rupture: 18 complete and 21 incomplete (dehiscence). Thirty-six women had a previous cesarean delivery: 33 low transverse, two classic, one low vertical. Of the 114,933 deliveries, 11,585 (10%) were in women with a previous cesarean delivery. Uterine rupture in those undergoing a trial for vaginal delivery (4516) was complete rupture in 2.4 per 1000 and dehiscence in 2.4 per 1000. There were no maternal deaths, and maternal morbidity was low in patients with dehiscence. In comparison, 44% of those with complete uterine rupture received blood transfusion (odds ratio 7.60, 95% confidence interval 1.14, 82.14, P =.025). Two perinatal deaths were attributable to complete uterine rupture, one after previous cesarean delivery. Compared with dehiscence, infants born after uterine rupture had significantly lower 5-minute Apgar scores (P <.001) and asphyxia, needing ventilation for more than 1 minute (P <.01). CONCLUSION: In 92% of cases, uterine rupture was associated with previous cesarean delivery. Uterine dehiscence was associated with minimal maternal and perinatal morbidity. In contrast, complete uterine rupture was associated with significantly more maternal blood transfusion and neonatal asphyxia. 相似文献
19.
We set out to describe the maternal and perinatal outcome of pregnancies in women >/= 45 years old at the time of delivery. A retrospective review of hospital deliveries after 28 weeks of pregnancy was performed at the Princess Badeea Teaching Hospital (PBTH) in North Jordan for patients delivered between 1 April 1994 and 31 December 1997. During the study period, there were 114 women aged >/= 45 years at delivery at the PBTH. The incidence was 3.3 per 1000 births. The median maternal age was 45 years. The majority of women (81.6%) were 45-46 years old. Maternal ages were 45 (n =64), 46 (n =29), 47 (n =9), 48 (n =8), 49 (n =2) and 50 (n =2) years. Median gravidity was 10, median parity was seven. Forty-four (38.6%) patients had obstetric complications. The most frequent complication was diabetes mellitus (9.6%), followed by hypertension (4.4%). Caesarean section was performed in 32.5%. There were nine stillbirths and four early neonatal deaths, the perinatal mortality rate was 114/1000 births. We conclude that women >/= 45 years old at delivery have high perinatal mortality rate and we also noted a higher incidence of placental abruption, placenta praevia and caesarean delivery, compared with a younger group of women. 相似文献
20.
Diabetes in pregnancy: a population-based study of incidence, referral for care, and perinatal mortality 总被引:1,自引:0,他引:1
During 1979 and 1980 in Washington State, 260 infants (live births plus fetal deaths greater than or equal to 20 weeks' gestation) were born to women with preexisting diabetes mellitus, the equivalent to a population-based incidence of 2.1 per 1000 total births. One quarter of these women had non-insulin-dependent diabetes prior to pregnancy. The perinatal mortality rate for all infants of diabetic mothers in this series was 108 per 1000, which was eight times the state perinatal mortality rate. Only 45% of births occurred in the five tertiary centers in the state, whereas 39% occurred in hospitals that had fewer than six deliveries per year complicated by overt diabetes. The mortality rate was slightly, but not significantly, lower among infants born in referral hospitals than among those born in primary-level hospitals. Congenital malformations accounted for 43% of the 28 perinatal deaths, and fetal losses between 20 and 27 weeks' gestation accounted for another 21%. During the 2-year study period there were only three cases in which antepartum care in nonspecialty centers may have contributed to a perinatal loss. 相似文献