Splenic pseudocyst: aspiration or cyst decapsulation

A 12 year old boy with a splenic pseudocyst is reported. Percutaneous drainage resulted in complete emptying but rapid reaccumulation. Cyst decapsulation with splenic preservation was curative and is recommended for definitive therapy of splenic pseudocysts.     

Splenic amyloidosis: a rare cause of spontaneous splenic rupture

A 62 year-old woman who presented with an atraumatic acute abdomen was discovered to have haemoperitoneum with splenic rupture on urgent computed tomography and was immediately referred for life-saving emergency splenectomy. Histopathological examination revealed secondary splenic amyloidosis. The patient was later found to be suffering from infective endocarditis secondary to her permanent cardiac pacemaker. This report describes a patient who could have suffered from a long-standing infected vegetation on a permanent cardiac pacemaker, which led to splenic amyloidosis and spontaneous splenic rupture.     

Bilateral first and second arch anomalies: a rare presentation

Branchial sinuses are one of the most common congenital anomalies present. They are usually unilateral; bilateral cases are present but are rare. The presentation of bilateral branchial sinus anomalies along with bilateral first arch anomalies is very rare. Here, we present a case of bilateral first arch anomalies co-existing with bilateral second arch anomalies in a patient with no related family history and no associated syndrome.     

Pancreatitis and hyperparathyroidism: Still a rare association!

BackgroundAmong the multitudinous etiologies of pancreatitis, primary hyperparathyroidism (PHPT) is rarely associated with pancreatitis. However, the cause and effect relationship between the two still evokes controversy. We aimed to study and characterize the nature of pancreatic disease in PHPT.MethodsA retrospective single-center study was carried out in North India over a period of 1 year (June 2015 to May 2016). All patients with pancreatitis were included. In patients with high calcium levels, Intact Parathyroid Hormone (iPTH) by Radioimmunoassay (RIA) and an Technetium 99m Sestamibi scintigraphy (MIBI-Tc-99m) scan were performed.ResultsDuring the study period, 70 patients with pancreatitis were admitted to our hospital (53 with acute pancreatitis [AP] and 17 with chronic pancreatitis [CP]). Of them, 5 patients (9.4%) were detected to have PHPT. The mean age of patients was 30.4 years (20–49 years) with 3 males and 2 females, including 1 pregnant female (29th week of gestation). Contrast enhanced computed tomography (CECT) abdomen was performed in 4 cases (excluding 1 pregnant patient) with mean Computed tomography severity index (CTSI) of 4.7 (2–8). Four patients were detected to have increased uptake in one of the parathyroid glands, and the fifth patient had an ectopic parathyroid uptake in the mediastinum. All the resected samples were identified as parathyroid adenoma on histology. The patients were followed up for 1 year with no reported recurrence of symptoms.ConclusionThe data suggest an association between pancreatitis (both acute and chronic) and hypercalcemia due to PHPT. A high calcium value during AP or CP should always draw suspicion and warrants corresponding investigations in search of endocrine or malignant cause.     

Chronic renal failure and tuberous sclerosis: a rare association

A 38 year old Saudi patient with tuberous sclerosis and chronic renal failure is described. The association of these two conditions has rarely been described. This case supports the observation that when chronic renal failure occurs in patients with tuberous sclerosis, cystic renal disease (with or without hamartomas) is more likely to be the underlying cause, rather than hamartomas alone.     

Splenic abscess. A rare pathology requiring a multidisciplinary approach

The clinical presentation of the splenic abscess is poorly specific. Its natural evolution is often fatal. The three case reports illustrate the difficulty of the diagnosis and management of this disease. Ultra sound and C.T. scan are the procedures of choice for the diagnosis and follow-up. The choice of the treatment depends on the number of abscesses, their volume, and also the presence of extrasplenic involvement. Antibiotherapy and interventional radiology have modified its therapeutical approach. Although the conservative treatment (antibiotherapy, transparietal drainage) is often successful, splenectomy is still indicated as a first line treatment, or as a salvage procedure.     

Splenic mass with remote trauma history: a management dilemma

Background  

Delayed presentation of splenic trauma is a well described entity.     

Vogt-Koyanagi-Harada syndrome, a rare association of Hodgkin's disease.

Vogt-Koyanagi-Harada syndrome (VKHS) is a well-documented clinical entity. We report the case of a 24 year old man who, within 5 months of the diagnosis of VKHS, developed Hodgkin's disease. Like VKHS, the aetiology of Hodgkin's disease is unknown. A viral factor has been suspected in the pathogenesis of both conditions. Similar immunological abnormalities have been described in both, and may be important predisposing factors.     

Concurrent preputial calculi and penile carcinoma--a rare association

A case of concurrent preputial calculi and carcinoma of the penis is reported. The causal relationship of both the lesions is still controversial and the possible common aetiopathogenesis of the entity is discussed.     

Renal artery stenosis in association with congenital anomalies of the kidney and urinary tract

Objectives:

To describe 8 cases of renal artery stenosis (RAS) in children with congenital anomalies of the renal tract.

Methods:

We conducted a retrospective chart review of 78 children with RAS who were followed up at Great Ormond Street Hospital, London, United Kingdom between 2003 and 2012. We used an interventional radiology database to identify all patients who had RAS confirmed by digital subtraction angiography and examined all cases of congenital anomaly of the renal tract that had been diagnosed during childhood.

Results:

We documented the following renal anomalies: multicystic dysplastic kidney (n=2), renal hypoplasia (n=1), congenital solitary kidney with hydronephrosis (n=1), and unilateral vesicoureteric reflux with poorly functioning kidneys (n=2). The anomaly was unknown in 2 cases. Seven children had unilateral nephrectomy at a median age of 2.5 years (range, 0.4-10 years) for various urological abnormalities. All children were confirmed to have RAS after presentation with hypertension at a median age of 10 (3.5-16.2) years. Angioplasty was performed in 7 children, of which 6 achieved control of their blood pressure on reduced medications.

Conclusion:

We highlight the association between RAS and other renal anomalies, which indicates that they could share a common genetic background.Renovascular disease (RVD) is an important cause of severe hypertension in children.1 It is caused by impairment of blood flow to a part or all one or both kidneys as a result of narrowing of renal arteries.2 It has several different etiologies, but the most common is fibromuscular dysplasia (FMD), in Western countries, and Takayasu arteritis (TA) in the developing world.1 The underlying diagnosis of children with RVH is not always well defined as some children experience renal artery stenosis (RAS) as part of a genetic syndrome, such as neurofibromatosis types 1 or Williams syndrome.1 It could also occur secondary to other conditions such as tumor surgery, radiation therapy, or rarely following neonatal umbilical artery catheterization.1 There is no known relationship between congenital abnormalities in the renal tract (CAKUT) and RVD. However, RVD has previously been reported in a few subjects in association with renal anomalies such as solitary kidneys, multicystic dysplastic kidney, and polycystic disease.3-13 In this study, we report a series of 8 patients with RAS after being diagnosed earlier in life with CAKUT.     

脾表皮样囊肿临床病理特征分析

目的 探讨发生于脾脏的表皮样囊肿(SEC)临床病理特征、诊断、鉴别诊断、治疗及预后.方法 收集2017—2020年深圳市人民医院4例SEC患者的临床病理资料及随访资料,对其病理形态特点及免疫组织化学进行观察分析,并复习相关文献.结果 4例患者均为女性,发病年龄19～34岁,平均(22±3)岁.2例为体检时偶然发现,无明...     

Klippel Feil syndrome with crossed fused renal ectopia with pelviureteric junction obstruction: A rare association

An 11-year-old female patient presented with congenital spinal deformity with a history of occasional pain in the right flank for a duration of six months. On evaluation, she was diagnosed to be a case of type III Klippel Feil syndrome (KFS) with crossed fused renal ectopia (left to right) and pelviureteric junction obstruction (PUJO) of the right moiety. The patient underwent successful pyeloplasty of the right moeity. To the best of our knowledge, this is the first reported case in the literature with a combination of KFS, crossed fused renal ectopia, and PUJO.     

Bilateral perisylvian infarct: a rare cause and a rare occurrence

Foix-Chavany-Marie opercular syndrome is a severe form of pseudobulbar palsy occurring due to bilateral anterior opercular lesions. We report a case of a 51-year-old man with sudden onset of inability to speak and dysphagia, and a history of synovial sarcoma of the right hand. Detailed language evaluation was normal. The patient had right upper motor neuron facial paresis and absent gag reflex bilaterally. Magnetic resonance (MR) imaging revealed acute and subacute infarcts involving the bilateral insular cortex. Two-dimensional echocardiography and cardiac MR imaging showed a mobile mass in the left atrium attached to the interatrial septum, which was likely a myxoma. Chest radiograph and computed tomography imaging of the chest revealed multiple cannonball shadows that were suggestive of secondaries in the lung. The probable cause of the cerebral lesions was the mass lesion in the heart or metastatic lesions from the synovial sarcoma. The cardiac surgeon and surgical oncologist recommended palliative care.     

胰腺假性囊肿的诊治体会:附32例报告

目的总结胰腺假性囊肿的诊治体会。方法回顾性分析32例胰腺假性囊肿患者的临床资料,根据囊肿部位,形成时间及囊壁厚度,采用保守治疗8例,经皮囊肿穿刺引流6例,开腹手术18例(外引流7例、内引流9例、囊肿切除2例)。结果全组无死亡病例,手术后并发症发生率为16.7%。随访3个月～6年,复发率6.3%。结论根据病情和病程选择合适的术式是治疗胰腺假性囊肿的关键。     

Splenic rupture in a patient with pelvic abscess and sepsis

A 49-year-old man underwent appendicectomy through a Lanz incision for necrotic appendicitis. He subsequently developed pelvic abscess in the postoperative period, which was drained under computed tomography (CT) guidance. The bacteriology of pus swabs taken during appendicectomy and abscess drainage revealed coliforms. Six days after appendicectomy, the patient had an acute collapse due to rupture of the spleen, which was treated by splenectomy. CT of the abdomen at the time of abscess drainage had confirmed a normal spleen. Histopathological examination of the spleen revealed nonspecific acute splenitis--red pulp congested and infiltrated with neutrophils complicated by rupture. We postulate the abdominal source of sepsis and associated inflammatory response as the cause for the splenic pathology and rupture.