瘤型麻风误诊1例

患者男,61岁.因颜面部暗红色斑丘疹、结节伴轻度瘙痒2年余,于2006年5月8日至广州中医药大学一附院就诊.     

皮肤肥大细胞增生症1例

<正>患者男,31岁。因躯干、四肢暗红色斑丘疹伴瘙痒2年余于2013年8月3日来我科就诊。患者2年前无明显诱因躯干、四肢出现数个粟粒至黄豆大暗红色斑丘疹,散在分布,轻微瘙痒。近3个月皮疹逐渐增多,以躯干为主,瘙痒加剧。既往健康,家族中无类似疾病患者。体格检查:一般状况良好,心脏、肺及腹部检查未见异常,浅表淋巴结未触及增大。皮肤科检查:躯干、四肢泛发粟粒至黄豆大圆形或椭圆形暗红色斑丘     

窝状角质松解症1例

临床资料 患者男,24岁.因双足底浸渍角化斑伴瘙痒1年余于2009年11月20日来我院就诊.患者为军人,平日双足较易出汗,1年前军训期间双足出汗多,双足底出现散在的淡黄色角化斑丘疹,部分中心有剥蚀及凹陷,偶伴瘙痒,曾自购足癣药外用治疗,未见明显改善.     

浅表性基底细胞癌1例

患者男,77岁.背部红斑加年,斑上出现角化性丘疹伴瘙痒1年,于2006年10月11日入院.患者20多年前于右侧背部出现一椭圆形红斑,伴轻微瘙痒,未予治疗.1年前,红斑上出现针头大角化性丘疹,搔抓后出现点状和线状结痂,表面有细碎鳞屑,红斑逐渐扩大为周边略高起、边界清楚的地图状斑片,曾对症治疗无缓解.     

巨大型汗孔角化症伴多发性鳞状细胞癌1例

1 临床资料患者男,64岁.左下肢暗红色斑块20年,伴局部多发性丘疹、结节、肿块2年.20年前无明显诱因左下肢出现一淡褐色蚕豆大斑丘疹.皮损面积逐渐扩大,边缘稍隆起,中央颜色减退,伴轻度萎缩,偶有轻度瘙痒.     

播散性浅表性汗孔角化症1例

1临床资料患者男,79岁,退休干部。面部及全身出现丘疹、斑块40年余,加重伴瘙痒3个月。40余年前,无明显诱因躯干起绿豆大的浅褐色斑和丘疹,边缘隆起,中央凹陷,皮损逐渐发展至头面部、躯干、四肢,四肢皮损因瘙痒反复搔抓而破溃和出血,逐渐增大,周边角化隆     

表现为发疹性瘙痒性丘疹的汗孔角化病

报告1例表现为发疹性瘙痒性丘疹的汗孔角化病.患者男,50岁.臀部丘疹伴剧烈瘙痒7年,逐渐融合成斑块,丘疹突然增多并累及双下肢1年.皮损组织病理检查符合汗孔角化病.给予角质剥脱剂外用及阿维A口服治疗4周,皮损暂无明显改善.     

泛发性炎症性线状疣状表皮痣1例

患者女,46岁,面部及右侧颈部、躯干、下肢丘疹伴瘙痒40余年。皮肤科情况:左侧额部、眶周及右侧面颊、下颌、颈部、背部、乳房、下肢见多发红色绿豆至黄豆大小斑丘疹、丘疹,部分融合成斑块,呈线状排列,表面有少量鳞屑、结痂,右足底角化过度。皮损组织病理:角化过度伴部分区域角化不全,真皮浅层少量炎性细胞浸润。诊断:泛发性炎症性线状疣状表皮痣。     

单发性丘疹型血管角皮瘤

正患者女,15岁。主诉:右膝关节外侧紫黑色斑丘疹3年。现病史:患者3年前无意中发现右膝关节外侧出现一绿豆大紫红斑,中央有一米粒大黑色丘疹,无明显自觉症状,未经诊治。其后斑丘疹逐渐增大,偶有瘙痒,表面略有角化过度。为明确诊断于2016年1月28日至我科门诊就诊,临床诊断疣状血管瘤?恶性黑     

长期服用囊虫丸致砷角化症和多发鲍温病1例

报告1例因长期服用囊虫丸所致的砷角化症和多发鲍温病。患者男,54岁。手足角化性丘疹20年,全身皮肤色素异常伴暗红色斑、破溃5年。曾因“脑囊虫病”间断服用“囊虫丸”10年。皮肤科情况掌跖部可见密集的点状角化型丘疹,其间杂以鸡眼角化型丘疹,双侧手指背、侧面起疣状角化型丘疹;全身弥漫性褐色色素沉着,其间杂以“雨滴样”色素减退斑;肩部、胸部、背部、臀部、股部等处见大小不等暗红色斑片、斑块,部分破溃。组织病理①砷角化症;②鲍温病。确诊。并对砷角化症进行简要综述。     

Flesh-coloured micropapules on the face and upper trunk

The following case report is of a 49 year old man who presented with a 20 year history of small asymptomatic flesh coloured firm papules which were concentrated on his face, neck and upper trunk. The diagnosis of multiple fibrofolliculomas of the familial type was reached.     

变应性肉芽肿病1例

报告1例变应性肉芽肿病。患者男,71岁。躯干、四肢红斑、瘙痒伴双下肢麻木1年。皮肤科检查见躯干、四肢泛发性红色斑块。组织病理示真皮血管周围及胶原束间多数中性粒细胞、嗜酸性粒细胞浸润。经强的松治疗后,皮损明显消退。     

成人炎性线状疣状表皮痣1例

患者男,40岁。手部角化性丘疹5年。查体见左手手背、中指及无名指背角化性丘疹,沿Blaschko线分布至肘关节,表面角化性鳞屑;无名指及中指远端指关节变形不能伸展。组织病理符合炎性线状疣状表皮痣。     

Reactive benign follicular mucinosis: a report of 2 cases

We report 2 cases of adolescents who developed follicular mucinosis following cutaneous infections. A 17-year-old adolescent boy was evaluated for a 2-week history of erythematous papules and plaques on his face and neck. One month prior to presentation a culture was taken that was positive for methicillin-sensitive Staphylococcus aureus-associated impetigo. Biopsies from 2 representative lesions demonstrated follicular mucinosis without evidence of folliculotropism or T cell gene rearrangements. A separate case involved a 17-year-old adolescent girl who presented with an edematous plaque on her right preauricular region and scattered erythematous papules and small annular plaques over her face 2 weeks following a herpes simplex virus type 2 (HHV-2) infection. on her face. Biopsy showed follicular mucinosis without evidence of epidermotropism or lymphocyte atypia. There was no herpesvirus cytopathic effect. The first case rapidly responded to an oral prednisone taper and the second case resolved over several weeks without further treatment.     

Unilateral colloid milium: a rare presentation

We report a case of a 31-year-old man with asymptomatic papules on one side of his face that had been present for 31 months. On physical examination, he had clusters of 1 to 4 mm skin colored translucent and dome-shaped, papules forming a plaque with a size of 4 x 3 cm on his left mandibular angle. Histopathology revealed atrophy of the epidermis with extensive deposition of pale eosinophilic homogenous deposits containing artifactual fissures that were PAS positive, diastase resistant, and Congo red negative. The final diagnosis was unilateral colloid milium.     

Skin metastases of malignant melanoma clinically simulating folliculitis

Cutaneous metastases of malignant melanoma were seen as small red papules with central hair resembling the typical clinical picture of folliculitis. This type of cutaneous metastasis was observed in a 51-year-old woman 12 months and in a 42-year-old man 30 months after wide excision of cutaneous malignant melanoma, in both cases located on the lower extremity. The first case presented a reflux metastasis, the second case a hematogenous metastasis on the contralateral thigh. Histological findings concurrently revealed metastases of malignant melanoma located at the cutaneous-subcutaneous interface beneath the hair follicle. This type of cutaneous metastasis could be easily excised in toto by means of a 6 mm diameter punch biopsy.     

良性血管周皮细胞瘤

报告1例良性血管周皮细胞瘤。患者女,39岁。左上肢出现暗红色增生性斑块伴疼痛半年。皮损为椭圆形暗红色斑块,表面无破溃,质地较硬,有明显触痛,周围有卫星状分布的针帽大暗红色丘疹。组织病理学检查：血管周皮细胞增生,细胞无异形性。网状纤维染色显示肿瘤细胞局限于网状纤维环的外围。诊断：良性血管周皮细胞瘤。     

A case of lichenoid purpura possibly caused by diltiazem hydrochloride

A 65-year-old Japanese man presented with itchy purpuric lichenoid papules of six months' duration on his legs and buttock. A topical glucocorticoid ointment was not effective. The biopsy specimen histologically showed a dense lichenoid infiltration of lymphocytes and histiocytes into the dermoepidermal junction; red blood cells were seen in the infiltration. Based on the clinical and pathological findings, we diagnosed this case as lichenoid purpura of Gougerot-Blum. The lesions disappeared when the diltiazem hydrochloride that he had been taking was discontinued.     

老年人足部血管肉瘤

报告1例老年人足部血管肉瘤.患者男,73岁.双足部出现多发性紫红色丘疹、结节和斑块2个月.组织病理检查示肿瘤位于真皮全层,瘤组织内有大量增生的血管,管腔不规则,免疫组化染色示瘤细胞CD31(+),CD34(+),Ⅷ因子相关抗原(一).诊断为血管肉瘤.