原发性先天性青光眼眼前段活体结构观察

目的:观察先天性青光眼的超声生物显微镜(UBM)图像特征并探讨先天性青光眼的发病机制。方法:采用高频、高分辨率的超声生物显微镜对6例先天性青光眼患者10只眼的房角、虹膜、睫状体等进行扫描和分析,并与7例正常人或无相关疾病患者的7只眼进行比较。结果:超声生物显微镜检查显示出原发性先天性青光眼的房角、虹膜、睫状体及巩膜突发育不良,虹膜基质薄,睫状体细小,巩膜突解剖特征不明显。原发性先天性青光眼组的虹膜厚度及睫状体大小的测量和统计学比较均明显小于正常对照组。结论:超声生物显微镜可以观察到常规眼科检查观察不到的部位,如睫状体、房角隐窝、虹膜后表面等等。原发性先天性青光眼具有虹膜基质薄、睫状体细小、巩膜突解剖特征不明显等特征,提示原发性先天性青光眼除了房角发育异常外,尚合并存在虹膜、睫状体巩膜突发育不良。其中虹膜、睫状体发育不良可能是先天性青光眼相对比较重要的发病机制。眼科学报1998;14:83—86。     

人眼睫状体在调节中形态与位置的动态变化

目的了解健康活体人眼在自发视远视近调节中,睫状体形态和位置动态变化的特点。方法利用超声生物显微镜(UBM)的50MHz高频换能器,对68例正常人眼注视远、近不同视标时睫状体形态、位置的变化进行动态观测和统计学分析。结果(1)视近调节时,睫状体前部厚度、睫状突长度、睫状体总面积和环形肌面积增大,睫状突宽度及内尖成角、睫状突与小梁、虹膜、巩膜突的距离,以及其和虹膜、巩膜的夹角减小,前房角开放程度变小。而睫状体后部厚度、纵行肌面积、巩膜虹膜夹角以及小梁虹膜夹角的差异无显著意义。(2)形态各参数间的变化相辅相成、高度一致,位置各参数亦然,但形态与位置之间关系无显著意义。结论人眼视近调节时,睫状体各部肌纤维协调收缩,尤其是环形肌收缩,使睫状突变得尖而细长,睫状体向前向内移动,松弛悬韧带,支持Helmholtz的调节松弛学说。UBM可实时观测人眼调节时睫状体各部分形态和位置等的变化情况。     

Scleral Thinning Documented by Ultrasound Biomicroscopy after Plaque Therapy for Anterior Ciliary Melanoma

Purpose: To evaluate, by ultrasound biomicroscopy (UBM), changes in scleral thickness after ruthenium-106 CCB and CCC plaque (Eckert & Ziegler BE-BIG GmbH, Berlin, Germany) therapy for anterior ciliary melanoma. Methods: Eleven patients with anterior ciliary melanoma underwent ruthenium-106 CCB and CCC plaque radiation with a radiation dose at the tumor apex of 80–100 Gy. UBM measurements performed prior to and after treatment were as follows: the largest prominence of the tumor perpendicular to the sclera and scleral thickness at scleral spur, 1.0 mm, and 2.0 mm posteriorly. Results: The article presents one year follow-up results for each of the 11 patients. The mean regression of the tumor of 24.3±9.31% was observed. The thinning of the sclera was statistically significant at the scleral spur (t=1.80, p ≤ 0.05) and at maximal tumor thickness (t=1.35, P=0.05). Conclusion: UBM documented significant thinning of the sclera at the scleral spur and overlying the maximal tumor thickness after Ru-106 CCB and CCC plaque radiation. Taking into consideration the shortcomings of the study—small sample size, insufficient probe resolution, and subjectively determined anatomic landmarks—observed minimal thickness change of the sclera does not necessarily mean its necrosis. However, thinning of the sclera documented at one year follow-up associated with very slow regression of the tumor indicates the need for the introduction of the CIA plaque treatment in our patients with anterior ciliary melanoma.     

应用超声生物显微镜检查原发性婴幼儿型青光眼的眼前节形态特征

目的 了解原发性婴幼儿型青光眼在活体状态下的眼前节组织结构特点。方法 应用超声生物显微镜,以５０ｍＨＺ的超高频超声探关,对３８例（５８只眼）原发性婴幼儿型青光眼的眼前节结构进行测量和动态学检查。结果 ＰＩＧ患儿无论发病早晚、病情轻呈年龄大小,其最主要的病变特征是巩膜突与留心 角顶点的相对位置发生变化,３／４患眼的巩膜突位于房角顶点外侧或后外方,１／４患眼的巩膜突虹膜根部附着处平行,眼状突长度和厚度     

Pathogenesis of transient high myopia after blunt eye trauma

OBJECTIVE: To determine the pathogenesis of transient high myopia after blunt eye trauma. DESIGN: Two observational case reports and literature review. METHODS: Refraction was measured in two patients with an autorefractometer in the acute and convalescent stages after a blunt eye injury. The anterior chamber angle, the ciliary body, and the choroid were examined by ultrasound biomicroscopy (UBM) in the acute and convalescent stages. In one patient, the anterior chamber depth, lens thickness, and axial length were measured by A-scan ultrasonography in the acute and convalescent stages. MAIN OUTCOME MEASURES: Comparison of the refraction, anterior chamber depth, lens thickness, axial length, and the UBM-determined appearance of the choroid and ciliary body during the acute stage with the values during the convalescent stages. RESULTS: The first patient showed a myopic shift of -9.75 diopters (D) and an anterior chamber shallowing of 0.94 mm measured 3 days after trauma by an air bag inflation compared with the measurements at the convalescent phase. UBM showed an annular ciliochoroidal effusion with ciliary body edema, anterior rotation of the ciliary processes, and disappearance of the ciliary sulcus. Eleven days after the injury, these UBM findings normalized, and the myopia decreased to -0.75 D, 27 days after trauma. The second patient had a myopic shift of -8.9 D compared with the convalescent phase, immediately after blunt trauma by a firework. Seven days after the injury, UBM revealed a partial cyclodialysis in addition to findings similar to those in the first patient. Ten days after injury, a myopic shift (-4.75 D), anterior chamber shallowing (by 1.1 mm), and thickening of the crystalline lens (by 0.27 mm) were observed compared with the convalescent phase. Associated UBM findings confirmed the anterior shift of the lens-iris diaphragm. Seventeen days after trauma, the UBM findings, including the cyclodialysis, were normalized, and the myopia had decreased to -1.0 D. CONCLUSIONS: Transient high myopia after blunt trauma is caused by anatomic changes in the ciliary body and crystalline lens. The anterior shift of the lens-iris diaphragm caused by ciliochoroidal effusion with ciliary body edema and thickening of the crystalline lens from blunt eye trauma are involved in traumatic high myopia.     

A case report on the change of the refractive power after a blunt trauma

PURPOSE: To determine the pathogenesis of transient myopia after blunt eye trauma. METHODS: In one patient, the refraction of both eyes (the left eye was injured, but the right eye was not) was measured with an autorefractometer. The cycloplegic refraction was measured at the early stage of trauma and again 3 months after the blunt eye injury. The angle and depth of the anterior chamber, the ciliary body, and the choroids were examined by ultrasound biomicroscopy (UBM) over 3 months. The depth of the anterior chamber, the thickness of the lens, and the axial length were measured by A-scan ultrasonography in both eyes. During the 3 months after the injury, we made comparisons between the menifest and the cycloplegic refractions, the depths of anterior chambers, the thickness of the lenses, the axial lengths, and the UBM-determined appearances of the angles and depths of the anterior chambers, the ciliary bodies, and the choroids in both eyes. RESULTS: We suspect that the depth reduction in the anterior chamber, the increase in anterior to posterior lens diameter, and the edema in the ciliary body are all related to the change in the refractive power following the blunt trauma. CONCLUSIONS: Ultrasound biomicroscopy (UBM) and ultrasonography of the anterior segment in the eye may be helpful to diagnose and confirm changes in the refractive power that occur after trauma.     

应用超声生物显微镜检查及诊断眼部睫状体脱离

目的探讨眼部睫状体脱离的形态学改变及其临床意义。方法应用超声生物显微镜（ｕｌｔｒａｓｏｕｎｄｂｉｏｍｉｃｒｏｓｃｏｐｙ,ＵＢＭ）对１７３例睫状体脱离的患眼与健眼的形态进行观察,并对其测量的相关参数进行统计学分析。结果所有睫状体脱离眼均为３６０°全周脱离,而非某一象限的脱离。ＵＢＭ探查睫状体脱离的特征性表现：巩膜与睫状体间存在无回声区,睫状突位置前移、前旋,睫状体平坦部向玻璃体中轴部位移动,部分患者可见睫状体平坦部呈层间分离。部分患者可显示虹膜、睫状体与巩膜附着点完全脱离,形成睫状体离断,离断的范围可为眼球的某一象限而非眼球全周,致使前房与睫状体上腔之间形成完全沟通的瘘口。脱离眼的前房深度（２１１５±５８９）μｍ较未脱离眼的前房深度（２７３６±４４１）μｍ浅（ｔ＝４．４９,Ｐ＜０．００１）,前房变浅的原因是睫状突前移、前旋导致虹膜根部膨隆。结论应用ＵＢＭ检查可以明确地诊断睫状体脱离,且不受屈光间质条件的限制,将为临床治疗提供可靠的依据。     

应用超声生物显微镜检测原发性婴幼儿型青光眼的眼前节形态特征

目的了解原发性婴幼儿型青光眼（ｐｒｉｍａｒｙｉｎｆａｎｔｉｌｅｇｌａｕｃｏｍａ,ＰＩＧ）在活体状态下的眼前节组织结构特点。方法应用超声生物显微镜（ｕｌｔｒａｓｏｕｎｄｂｉｏｍｉｃｒｏｓｃｏｐｙ,ＵＢＭ）,以５０ｍＨｚ的超高频超声探头,对３８例（５８只眼）原发性婴幼儿型青光眼的眼前节结构进行测量和动态学检查。结果ＰＩＧ患儿无论发病早晚、病情轻重或年龄大小,其最主要的病变特征是巩膜突与房角顶点的相对位置发生变化,３／４患眼的巩膜突位于房角顶点外侧或后外方,１／４患眼的巩膜突与虹膜根部附着处平行。睫状突长度和厚度均大于同龄正常儿童。睫状突向前、向内移位,部分与虹膜相贴。结论ＰＩＧ患儿的巩膜突与房角顶点相对位置的改变,提示巩膜突发育不良或虹膜附着点靠前,这是原发性婴幼儿型青光眼发病的病理基础。     

Ultrasound biomicroscopic study of ciliary body thickness in eyes with narrow angles

PURPOSE:To determine the ciliary body thickness and other biometric findings in eyes with narrow angles.METHODS:Eighteen otherwise normal eyes with narrow angles in 18 Japanese patients and 18 normal control eyes with open angles in 18 age-matched and sex-matched Japanese patients were studied. A-scan ultrasonography was performed to measure anterior chamber depth, lens thickness, axial length, and relative lens position. Ultrasound biomicroscopy was also performed to obtain measurements of the anterior ocular structures, including anterior chamber depth and ciliary body thickness at sites 1 mm and 2 mm posterior to the scleral spur (positions 1 and 2, respectively). RESULTS:Compared with normal control eyes, the narrow-angle eyes showed a shallower anterior chamber (narrow angle, 1.87 +/- 0.27 mm; control, 2.69 +/- 0.26 mm; P <.0001), a thicker lens (4.97 +/- 0.49 mm, 4.26 +/- 0.53 mm; P <.0001), a more anteriorly located lens (2. 21 +/- 0.13, 2.35 +/- 0.14; P <.0001), a shorter axial length (22.70 +/- 0.97 mm, 23.41 +/- 0.86 mm; P =.012), and a thinner ciliary body (position 1: 454 +/- 107 microm, 602 +/- 86 microm; P <.0001; position 2: 203 +/- 50 microm, 321 +/- 68 microm; P <.0001). Lens thickness was significantly correlated with ciliary body thickness at positions 1 (R(2) = 0.34; P =.0001) and 2 (R(2) = 0.43; P <.0001). Anterior chamber depth was significantly correlated with ciliary body thickness at positions 1 (R(2) = 0.48; P <.0001) and 2 (R(2) = 0.56; P <.0001).CONCLUSION:Thinning of the ciliary body may be one of the important factors associated with the anterior location of the lens, the increased lens thickness, and the decreased anterior chamber depth in eyes with a narrow angle.     

Comparison of uveal parameters between acute primary angle-closure eyes and fellow eyes in South Indian population

Purpose:To analyze the ocular biometric parameters of eyes with acute primary angle closure (APAC) as compared to fellow eyes.Methods:A cross-sectional study was conducted on 27 patients presenting with recent onset APAC to a tertiary eye institute in India. Anterior and posterior ocular biometric parameters were measured simultaneously by anterior segment optical coherence tomography (AS-OCT), A-scan, ultrasound biomicroscopy (UBM), and B-mode ultrasonogram (USG). The parameters measured were anterior chamber depth (ACD), anterior chamber angle (ACA), angle opening distance (AOD500, AOD750), lens vault (LV), axial length (AL), ciliary body thickness maximum (CBTmax) and at the point of scleral spur (CBT0), anterior placement of the ciliary body (APCB), and retinochoroidal thickness (RCS).Results:Mean age ± SD of patients with APAC was 55.66 ± 7.2 years with female preponderance (21:6 patients). Mean presenting IOP ± SD of the affected eye and fellow eye were 54.74 ± 11.67 mm Hg and 18.7 ± 11.67 mm Hg, respectively. Eyes with APAC had statistically significant narrower anterior ocular biometric parameters, higher LV, decreased ciliary body thickness, more APCB, and longer AL than the fellow eyes. CBTmax is the only variable that had significance (b = −0.421,95% CI: −0.806 to − 0.035, P = 0.034) in the univariate analysis with RCS thickness in APAC eyes. Further, there was a correlation between CBT0 and APCB with CBTmax both in univariate (b = 0.894, P < 0.0001 and b = −0.351, P = 0.039) and multivariable analysis (b = 0.911, P < 0.0001 and b = −0.416, P = 0.016)Conclusion:Compared to the fellow eyes, APAC eyes had different ocular biometric parameters. In addition to known biometric parameters associated with pupillary block (narrower anterior biometric parameters-ACA, ACD, and AOD), our study found multiple nonpupillary block factors such as higher lens vault and thinner and more anteriorly placed ciliary body to be associated with APAC.     

Ultrasound biomicroscopic study of ciliary body changes in the post-treatment phase of Vogt-Koyanagi-Harada disease

AIMS: To investigate the usefulness of ultrasound biomicroscopy for evaluating changes in the ciliary body in patients with Vogt-Koyanagi-Harada disease. METHODS: Ultrasound biomicroscopy was used to evaluate 14 eyes of seven patients diagnosed with Vogt-Koyanagi-Harada disease. Cross sectional images of the ciliary body and thickness of the pars plana 3.0 mm posterior to the scleral spur were examined. Predicted thickness of the pars plana was obtained by multiple linear regression analysis of thickness in the acute phase and in the remission phase. RESULTS: In the active phase, the cross sectional images showed a shallow anterior chamber in eight of the 14 eyes, ciliochoroidal detachment in five eyes, and a thickened ciliary body in all 14 eyes. Internal reflectivity of the ciliary stroma was low, with ciliary processes being unclear in 13 eyes. One month after steroid treatment, slit lamp examination findings were normal in 14 eyes. 10 eyes of five patients were examined by ultrasound biomicroscopy at this stage. Ciliochoroidal detachment was no longer seen in any eye. Internal reflection of the ciliary stroma became relatively homogeneous, and the ciliary processes were seen, though not clearly. However, the pars plana remained thickened. The actual thickness was greater at 1 month after steroid treatment than the predicted thickness for the remission phase. In the remission phase, the internal reflection was homogeneous and the ciliary processes were delineated clearly in all 14 eyes. CONCLUSION: Objective, quantitative evaluation of the ciliary body is possible with ultrasound biomicroscopy during the course of Vogt-Koyanagi-Harada disease. Ultrasound biomicroscopy is useful in determining disease activity in the anterior segment and in monitoring the clinical course, and it may improve evaluation of the efficacy of treatment.     

Anterior segment changes during accommodation in eyes with a monofocal intraocular lens: high-frequency ultrasound study

PURPOSE: To analyze anterior segment structure changes during accommodative stimuli after monofocal intraocular lens (IOL) implantation using 2 ultrasound biomicroscopy (UBM) systems. SETTING: Department of Ophthalmology, University of Verona, Verona, Italy. METHODS: Twenty-six eyes (23 patients) with 1 of 4 monofocal IOL types were studied. Five to 9 months postoperatively, the patients were examined by high-frequency UBM using the HiScan system (Optikon 2000 SpA) and UBM 840 system (Carl Zeiss Meditec). Anterior chamber depth (ACD), iris-zonule distance, anterior chamber angle (ACA), scleral-ciliary process angle, and iris-ciliary process angle were measured using both systems. The iris-ciliary process distance and scleral spur perpendicular-sulcus distance were measured with the UBM 840 system and the sulcus-sulcus distance and capsular bag-IOL position with respect to ciliary process apex, with the HiScan system. Two experienced examiners performed all measurements. RESULTS: All parameters except the horizontal iris-ciliary process distance and vertical ACA measured by the UBM 840 system and horizontal ACA by the HiScan system showed significant variation during accommodation. An anterior shift of the IOL-capsular bag ciliary processes--sulcus-zonular iris complex was observed. A simultaneous centripetal shift of ciliary bodies and processes, shown by a reduction in sulcus and capsular bag diameter, was also observed. CONCLUSION: Anterior segment structures demonstrated accommodative movement on UBM after implantation of standard monofocal IOLs.     

应用超声生物显微镜研究睫状肌麻痹剂对眼前节结构的影响

目的应用超声生物显微镜观察局部应用睫状肌麻痹剂前、后眼前节形态结构的改变及其与眼压的关系,同时对睫状体厚度、睫状体晶体赤道部距离进行观察。方法以４８只正常眼为研究对象,在局部应用２％后马托品前、后分别进行眼前节结构的超声生物显微镜定量测定,并测量眼压。对其结果进行统计学分析。结果用药后在反映房角改变的参数中,小梁虹膜夹角减小,房角开放距离２５０减小,虹膜厚度１增厚,前房加深,虹膜晶体接触距离缩短,差异均有显著性（Ｐ＜０．０５）;在反映睫状体改变的参数中,睫状体和睫状突的厚度减小,巩膜睫状体夹角增大,虹膜悬韧带距离减小,睫状体晶体距离增大,差异有显著性（Ｐ＜０．０５）。应用睫状肌麻痹剂后,眼压由２．３５±０．４６ｋＰａ（１ｋＰａ＝７．５ｍｍＨｇ）升高至２．４３±０．４７ｋＰａ,但差异无显著性（Ｐ＞０．０５）。结论局部应用睫状肌麻痹剂后,前房加深、房角变窄、睫状体变薄且向后运动、睫状体晶体距离增大。超声生物显微镜能动态观察眼前节结构的改变并行定量测定,在眼前节形态学研究中具有优越性。     

Narrowing of the anterior chamber angle during Valsalva maneuver: a possible mechanism for angle closure

PURPOSE: To evaluate changes at the anterior chamber angle during Valsalva maneuver in eyes suspected to have a primary adult glaucoma. METHODS: Seventy-six consecutive patients underwent recording of applanation tonometry, measurement of the anterior chamber angle recess, angle opening distance, angle recess area, scleral spur-iris root distance, iris thickness, iridociliary angle, ciliary body thickness, anterior chamber depth, and pupil size on ultrasound biomicroscopy before and during the Valsalva maneuver. The Valsalva maneuver was standardized to a pressure of 40 mmHg for 15 seconds, using a manometer. RESULTS: The mean baseline intraocular pressure changed from 19.5+/-4.1 mmHg to 29.5+/-4.8 mmHg during Valsalva (p<0.0001). The anterior chamber angle recess narrowed from 17.9+/-9.5 to 7.8+/-9.2 degrees (p=0.0001). The angle recess area diminished from 0.15+/-0.14 mm2 to 0.14+/-0.12 mm2 (p=0.03) and the scleral spur to iris distance decreased from 0.19+/-0.2 mm to 0.16+/-0.18 mm (p=0.0001). The iridociliary angle narrowed from 72.6+/-33.5 degrees to 62.5+/-32.8 degrees (p=0.04). There was a significant increase in the thickness of the ciliary body, from 0.99+/-0.19 mm to 1.12+/-0.16 mm (p=0.001) and in iris thickness from 0.47+/-0.07 mm to 0.55+/-0.09 mm (p=0.0001). There was no significant change in the angle opening distance, anterior chamber depth, or pupillary diameter. A significant narrowing of the angle to less than 5 degrees was seen in 37 eyes, with iridocorneal apposition present in 28 eyes. After multivariate regression analysis it was found that the baseline ciliary body thickness and angle recess were significant predictors of narrowing of the angle (R2=96.1%). CONCLUSIONS: Significant elevation of the intraocular pressure, narrowing of the anterior chamber angle recess, thickening of the ciliary body, and increase in the iris thickness is seen during the Valsalva maneuver. The Valsalva maneuver may lead to angle closure in eyes anatomically predisposed to primary angle closure glaucoma.     

视网膜脱离巩膜环扎术后眼前节结构的初步观察

目的 观察巩膜环扎术后眼前节结构的变化,探讨术后继发性闭角型青光眼的发病机制。方法 应用超声生物显微镜检查３０例（３３只眼）孔源视网膜脱离患者术前、后３－７天的活体奶前节形态结构,并分别进行定量测定,检查结果经统计学分析两组间配对ｔｓｗｃｗ,以Ｐ〈０．０５作为差异有显著性标准。结果 术前１只眼存在裂隙样睫状体脱离。术后１１只眼（３３．３％）发生睫状体脱离,睫状体增厚水肿;术前睫状体厚度为（８２１．     

Ultrasound biomicroscopic imaging demonstrate thinner ciliary body thickness in eyes with angle closure

AIM: To compare the ciliary body thickness between eyes with primary angle closure (PAC) and primary angle-closure glaucoma (PACG) with the normal eyes, and to investigate the association between ciliary body thickness and ciliary processes situation. METHODS: In this cross-sectional study, 57 patients with PAC/PACG were matched to 57 normal subjects after propensity score matching (PSM) adjusting for age and gender. All subjects underwent conventional ocular examinations and ultrasound biomicroscopy (UBM) examination, among which the patients with PAC/PACG performed the examinations one month after laser peripheral iridotomy (LPI). Quantitative parameters were measured, which included ciliary body thickness at the position of 1 mm posterior to the scleral spur (CBT1), trabecular-ciliary process distance (TCPD) and trabecular-ciliary process angle (TCA). RESULTS: Eyes with PAC/PACG presented significantly thinner CBT1, shorter TCPD and smaller TCA (P<0.001) than the normal eyes, both in comparison of the means of four quadrants and in comparisons of each quadrant. After removing images with peripheral anterior synechia (PAS), the same results were also found in comparisons between the two groups. Significant correlations were found between TCPD (R2=0.537, P<0.001) and TCA (R2=0.517, P<0.001) with CBT1. CONCLUSION: Eyes with PAC/PACG have thinner ciliary body thickness and more anteriorly situated ciliary processes. Thinner ciliary body thickness is associated with anterior situation of the ciliary processes.     

A case of acute angle-closure glaucoma secondary to posterior scleritis in patient with Sturge-Weber syndrome

BACKGROUND: Sturge-Weber syndrome has been known to be frequently associated with facial cutaneous angioma and ipsilateral glaucoma. However, as far as we know, no cases accompanied by acute angle-closure glaucoma have been reported in patients with Sturge-Weber syndrome. CASE: A 14-year-old boy with unilateral acute angle-closure glaucoma secondary to posterior scleritis associated with Sturge-Weber syndrome is described. OBSERVATIONS: Slit-lamp examination revealed diffuse episcleral venous hemangioma in the right eye. With ultrasound biomicroscopy, a forward shift of the lens-iris diaphragm, a swelling of the ciliary body, and an anterior rotation of the ciliary processes with annular choroidal effusion were detected. The patient responded well to treatment with systemic corticosteroids and cycloplegics. CONCLUSIONS: In our patient, inflammatory changes of the sclera, including swelling of the ciliary body, choroidal effusion, an anterior rotation of the ciliary processes at the scleral spur, and swelling of the lens, leading to closure of the anterior chamber angle, were suggested to be the major mechanisms of intraocular pressure elevation.     

Ultrasound biomicroscopic characteristics of the anterior segment in primary congenital glaucoma

PURPOSE: To evaluate qualitatively and quantitatively ultrasound biomicroscopic (UBM) features of the anterior segment in eyes with primary congenital glaucoma. METHODS: UBM of 45 eyes of patients with primary congenital glaucoma (39 previously operated and 6 unoperated eyes) and 28 control eyes were included in this study. UBM parameters were correlated with ocular biometry. Iris thickness, ciliary body thickness, ciliary body-lens distance, posterior chamber depth, and anterior chamber angle were measured and compared with control eyes. Other features of the anterior segment were qualitatively evaluated. RESULTS: A thin, stretched-out ciliary body and abnormal tissue at the iridocorneal angle were features seen in 90% of UBM scans. Iris thickness and stretched zonules correlated with the axial length (r = -0.6 and 0.58, respectively; p = 0.04) but not with the mean corneal diameter. Abnormal insertion of the ciliary body to the posterior surface of the iris was noted in eight eyes (17%). CONCLUSIONS: The present study documents characteristic anterior segment dysplasia and ciliary body anomalies in patients with primary congenital glaucoma.     

Ciliary body thickness increases with increasing axial myopia

PURPOSE: To assess the relationship between ciliary body thickness and refractive error. DESIGN: Prospective observational case series. METHODS: We enrolled 75 eyes of 75 patients with no history of intraocular surgery or use of anti-glaucoma medication. Axial length was measured by A-scan ultrasonography. Ciliary body thickness (CBT) was measured by two masked observers on radial-section images of the temporal corneoscleral limbus, acquired with ultrasound biomicroscopy (UBM) at 2 and 3 mm posterior to the scleral spur (CBT2 and CBT3, respectively). RESULTS: Refractive error was inversely correlated with CBT2 and CBT3 (r = -.64 and r = -.52, P < .0001, respectively). Axial length was correlated with CBT (r = .66 and r = .57, P < .0001, for CBT2 and CBT3, respectively). CONCLUSION: CBT increases with increasing myopia and axial length.     

Ciliochoroidal effusion after remission of lens-induced glaucoma detected by ultrasound biomicroscopy

PURPOSE: To report the results of ultrasound biomicroscopy(UBM) cases of ciliochoroidal effusion after a lens-induced glaucoma attack. CASES: Case 1 was an 83-year-old female. She had shallow anterior chamber with expanded cataract with exfoliation in her right eye. Intraocular pressure(IOP) of the right eye was 64 mmHg. On the next day, IOP was reduced to 16 mmHg by conservative therapy. UBM showed circumference ciliochoroidal effusion in the right eye. On the 5th day, IOP increased to 38 mmHg. UBM was repeated and showed the disappearance of ciliochoroidal effusion. On the 9th day, phacoemulsification was done to treat the lens induced glaucoma attack. Two weeks after operation, IOP of the right eye was 6 mmHg and UBM showed ciliochoroidal effusion. Case 2 was an 85-year-old female. She had been diagnosed by an ophthalmologist as having an attack of lens-induced glaucoma in her left eye. IOP was 46 mmHg. When she was referred to us, IOP was decreased to 24 mmHg and ciliochoroidal effusion was observed in her left eye by UBM. CONCLUSION: We report two cases of ciliochoroidal effusion associated with lens-induced glaucoma attack. UBM is useful to observe changes in the ciliary body after lens-induced glaucoma attack.