Oral tuberculosis: a clinical evaluation of 42 cases

OBJECTIVES: A retrospective review of a large series of oro-facial cases of tuberculosis to analyse clinical, histopathological, and radiological aspects, as well as those of chemotherapy. MATERIALS AND METHODS: A total of 42 cases of tuberculosis of the oro-facial region were examined. Thirteen patients had a primary form and 29 a secondary form of the disease. Diagnosis was based on careful clinical examination, Mantoux reaction, histopathological examination, microbiological cultures and immunological investigation with the detection of antibodies against Mycobacteria in the patients' serum (ELISA). RESULTS: Cases examined consisted of 27 males and 15 females. The age range was 3 to 73 years (mean age 31 years). Clinical manifestations comprised oral ulcers in 69.1%, bone involvement in 21.4%, and salivary gland and/or lymph node involvement in 14.3%. A total of 79.4% patients with secondary disease had pulmonary lesions, 15 of whom showed clinical and radiological signs of activity; there was one case of bilateral renal lesions and two of skin lesions. CONCLUSIONS: Oro-facial tuberculosis is often difficult to diagnose and it should be an important consideration in the differential diagnosis of lesions that appear in the oral cavity. The most important diagnostic tools remain a careful clinical evaluation, biopsy for histologic study, as well as acid-fast stains, culture, and immunological assays, and skin testing.     

人头发自由基检测在口腔颌面部恶性肿瘤诊断中的意义

作者应用电子自旋共振技术（ＥＳＲ）分别对正常人、口腔颌面部良恶性肿瘤、口腔粘膜病患者共３２４例的头发进行自由基测定，并与病理诊断相对照。结果表明，它们的阳性率分别为５．９％，６．１％，８４．５２％及９．１％。其中恶性肿瘤与正常人及良性肿瘤相比较，差别均较显著（Ｐ＜０．０１）。部分恶性肿瘤患者经治疗后，ＥＳＲ饱和功率点后移，上升到临界水准以上（＞１０．０ｍＷ），ＥＳＲ转阴。表明用ＥＳＲ早期诊断恶性肿瘤、追踪疗效具有一定临床价值。作者还结合检测资料对ＥＳＲ在监测肿瘤复发、监视白斑癌变等方面的意义进行了讨论。     

口腔颌面部错构瘤(附7例报告)

目的 研究口腔颌面部错构瘤的病理特征及鉴别诊断。方法 分析了7例错构瘤病例的临床资料和组织学表现。结果 口腔颌面部错构瘤有其自身的组织学和临床特征。结论 通过组织学检查和其临床表现特征,可以正确地诊断错构瘤。     

2050件金属烤瓷修复体边缘适合性临床观察

目的：临床观察金属烤瓷冠、桥修复体的边缘适合性，并对其边缘适合性差的表现，进行临床和技工室两方面的原因探讨。方法：对2050件金属烤瓷冠，桥修复体在每件试藏时按事先拟定的指标，逐一进行临床检查并记录。结果：金属烤瓷单冠的边缘适合性差占1％，而金属烤瓷固定桥或联冠边缘适合性差占5．84％，结论：金属烤瓷单冠的边缘适合性远较金属烤瓷固定桥或联冠理想，在固定桥或联冠的制作中，临床要特别注意基牙的共同就位道，技工室在有条件时可分段锻造，焊接完成。