精索脂肪肉瘤1例报告并文献复习

目的:探讨精索脂肪肉瘤的临床特点及诊治方法。方法:回顾性分析1例精索脂肪肉瘤临床资料,结合相关文献对其临床诊治进行讨论。结果:患者行左侧精索肿瘤根治性切除术。术后病理诊断为精索脂肪肉瘤。随访5个月无复发及转移。结论:精索脂肪肉瘤是一种罕见的疾病,影像学及实验室检查无特异性。推荐的治疗方法为根治性睾丸切除术及局部肿瘤广泛性切除术;对于中、高级分化的肿瘤可以辅助放疗。化疗效果尚未明确。     

复发性双侧精索肉瘤1例

患者,5 3岁。1个月前无明显诱因出现左腹股沟肿块,初起时约黄豆大小,逐渐长大为1 .0cm×1 .5cm。患者无畏寒、发热,无尿频、尿急、尿痛及肉眼血尿。患处不伴疼痛,行走较久后局部酸胀感。2 0 0 3年1 0月1 6日就诊,门诊行腹股沟CT检查提示“左腹股沟肿块”。1 981年患者因左精索肿块在外院行左侧精索、睾丸、附睾切除术,术后病理诊断为“(精索)脂肪肉瘤”。此后2 0余年复发1 4次,有时1年复发1～2次。1 996年出现右侧精索肿块,行右侧精索肿块切除术,术后病理诊断亦为精索脂肪肉瘤。复发后均行手术切除并术后放疗。体检:一般情况好。阴茎发育良…     

精索多形性脂肪肉瘤1例报告并文献复习

目的：分析并总结精索脂肪肉瘤患者的临床表现及其诊断及治疗方法。方法：回顾性分析我院收治的1例精索脂肪肉瘤患者的临床资料：左侧阴囊内有-9．0cm×9．4cm×6．7cm肿块,B超检查示左侧阴囊内存在一非均质实性包块;MRI显示左侧阴囊内有实质性肿瘤,未见肿大淋巴结。血清肿瘤标志物13-HCG、CEA、PSA和AFP检查均无异常。手术切除肿瘤的同时行左侧阴囊部分切除术。结果：术后病理检查提示为多形性混合型脂肪肉瘤。患者术后恢复顺利。结论：精索脂肪肉瘤是一种罕见的泌尿生殖系肿瘤,诊断主要依据病理检查结果确定;治疗以根治性睾丸切除术为主要方式,辅助放疗、化疗疗效不确切;预后与肿瘤组织病理类型密切相关,局部复发很常见,需长期随访。     

1例高分化精索脂肪肉瘤1年内3次手术治疗报告并文献复习

目的 探讨高分化精索脂肪肉瘤的临床特点及诊治方法。方法 回顾性分析1例多次复发高分化精索脂肪肉瘤患者的临床资料,结合相关文献对其临床诊治进行讨论。结果 患者初次手术行右侧精索区脂肪组织送检。术后病检提示：高分化脂肪肉瘤。随访1年内,因复发分别行双侧睾丸根治性切除术及腹膜后肿瘤切除术。结论 精索脂肪肉瘤是极为罕见的疾病,目前尚缺乏标准的治疗方案,局限性病变完整手术切除是关键,局部复发手术治疗仍是首选,无法达到R0切除,术后复发率极高,脂肪肉瘤对放疗和化疗不敏感,仍期待更确切的辅助疗法联合应用于该疾病的治疗。     

保留神经腹膜后淋巴结清除术治疗睾丸肿瘤

目的探讨保留神经腹膜后淋巴结清除术(RPLND)在低期睾丸肿瘤治疗中的作用和效果。方法1999年6月至2003年7月收治睾丸肿瘤患者13例,年龄24～41岁,平均29岁。肿瘤位于左侧9例,右侧4例,大小2cm×3cm×2cm～9cm×6cm×5cm。临床分期:Ⅰ期11例,均为非精原细胞瘤;ⅡA期1例,为畸胎瘤(CT示腹膜后转移灶1cm×2cm);ⅡC期1例,为精原细胞瘤(CT示腹膜后转移灶10cm×9cm)。12例非精原细胞瘤者根治性睾丸切除术后1～4周行保留神经RPLND,1例精原细胞瘤者根治性睾丸切除术后行3疗程BEP方案化疗后行保留神经RPLND。结果术后病理分期:Ⅰ期11例,ⅡA期2例,其中ⅡC期精原细胞瘤患者化疗后分期降为Ⅰ期。13例术后均无肠梗阻、淋巴瘘和体位性低血压。术后2周复查时血AFP和βHCG均降至正常范围。术后8～12周均恢复射精功能。随访18～64个月,平均39个月,无肿瘤复发或转移。结论对于青壮年患者,保留神经RPLND是治疗低期非精原细胞瘤和化疗后降期的精原细胞瘤的首选方法。     

精索及淋巴结转移瘤一例

患者,男,64岁。1988年5月突发阴囊胀痛,并可扪及雀蛋大小包块,当时按附睾炎治疗无效而入院.患者3年前曾在本院行胃癌扩大根治术,病理诊断:胃小弯溃疡型高分化腺癌、浆膜层浸润,淋巴结无转移。术后反复化疗,多次胃镜检查未见复发。入院体检:右腋窝可扪及-2cm×2cm质硬淋巴结。右侧精索远端可扪及3cm×3cm×4cm包块,质硬,表面不光滑,透照试验阴性,睾丸     

双侧精索Burkitt淋巴瘤1例

患者男,2岁。因发现左、右侧腹股沟肿块1 5天和30天入院,无特殊病史。入院体检:精神状态好,营养一般,轻度贫血貌,全身浅表淋巴节未扪及,心肺无异常,腹部平软,无腹胀及压痛,未触及包块。左右侧精索分别可触及1 .5cm×1 .0cm和2 .5cm×1 .4cm大小卵圆形肿块,质硬,表面呈结节状,无压痛,活动度好,可随睾丸牵拉而移动,肿块距睾丸约1 .6cm。双侧睾丸无异常。实验室检查:白细胞5 .7×1 0 9/L ,血红蛋白7.6g/L。X线胸片及腹部平片未见异常。彩超示双侧精索囊性占位性病变,有少量腹水。与2 0 0 3年1月7日行右侧精索肿瘤探查术。术中见肿瘤位于右侧…     

精索去分化脂肪肉瘤临床与病理分析(1例报道附文献复习)

目的探讨精索去分化脂肪肉瘤临床与病理特点。方法回顾性分析1例精索去分化脂肪肉瘤临床与病理资料,结合相关文献复习对其临床诊治进行讨论。结果患者以阴囊肿块行右侧侧精索肿瘤根治性切除术。术后病理诊断为精索去分化脂肪肉瘤。随访2年无复发及转移。结论精索脂肪肉瘤是一种罕见的疾病,影像学及实验室检查无特异性。术前诊断困难,推荐的治疗方法为根治性睾丸切除术及局部肿瘤广泛性切除术。     

同侧乳腺黏液型脂肪肉瘤合并浸润性导管癌及纤维腺瘤：附1例报告并文献复习

目的：分析乳腺黏液型脂肪肉瘤合并浸润性导管癌及纤维腺瘤的临床及病理特点。方法：报告1例同侧乳腺黏液型脂肪肉瘤合并浸润性导管癌及纤维腺瘤并结合文献进行复习。结果：该患者发现左乳3个互不相连的肿物。镜下3个肿物分别诊断为黏液型脂肪肉瘤、浸润性导管癌及纤维腺瘤。免疫组化显示黏液型脂肪肉瘤与浸润性导管癌分别为表达上皮源性及间叶源性标志物。治疗方式为早期根治性手术切除,术后辅助化疗。该例术后随访12个月未见复发或转移。结论：乳腺黏液型脂肪肉瘤少见,同时伴发浸润导管癌以及纤维腺瘤尤为罕见。治疗方式应首选根治性手术切除及术后辅助化疗。

     

同胞兄弟睾丸精原细胞瘤二例报告

同胞兄弟发生睾丸精原细胞瘤极为罕见,国内尚未见报告.我院曾遇2例,现报告如下。例1 男,29岁,未婚。因右睾丸肿大5月于1973年6月2日入院。既往无睾丸外伤史。体检:右睾丸触及5×4×4 cm肿块,稍硬,无压痛,表面尚光滑,精索无异常;先侧睾丸、附睾、精索均正常。两侧腹股沟淋巴结不肿大。拟诊:右睾丸肿瘤。6月7日在硬膜外麻醉下行根治性右睾丸切除术。病理诊断:右睾丸精原细胞瘤。术后10天行腹主动脉旁髂窝淋巴结预防性放疗,3周照射总量3600×10(-2)Gy。随访18年,无肿瘤复发。     

Giant liposarcoma of the spermatic cord: report of a case

We report a case of a 3,100 g giant liposarcoma of the spermatic cord in an 88-year-old man. The tumor had been present for 13 years. The pathological diagnosis was well-differentiated liposarcoma of sclerosing type. Twenty-two cases of spermatic cord liposarcoma found in the Japanese literature were reviewed. This case was thought to be of the largest tumor and oldest patient in the Japanese literature.     

Pleomorphic spermatic cord liposarcoma: A case report and review of management

Liposarcoma of the spermatic cord is very rare, representing about 7% of para testicular sarcomas. It is considered to be one of the highest malignancy grades.We present a case of a liposarcoma of the spermatic cord in a 45-year-old male complaining of a progressive painless swelling in the right inguinoscrotal region. Ultrasonography and computed tomography findings were compatible with liposarcoma of the spermatic cord. We performed a right radical orchiectomy with a wide resection of the mass. Histological examination confirmed the diagnosis and showed a pleomorphic subtype.The mainstay of management of spermatic cord liposarcoma is wide excision with radical orchiectomy. The most important factors for prognosis are the histologic subtype and surgical margin status. Adjuvant radiotherapy should be considered in cases at high risk for local recurrence. Long-term surveillance is mandatory.Liposarcoma of the spermatic cord is an uncommon para testicular tumor which should be part of the differential diagnosis of inguinoscrotal mass. A radical inguinal orchiectomy with wide resection of the soft tissue mass and the spermatic cord are the key to longest local and systemic disease-free survival.     

Local recurrence of spermatic cord liposarcoma: a case report

A 46-year-old man had undergone radical high orchiectomy because of a tumor of the right spermatic cord. Pathological diagnosis was atypical lipomatous tumor. Six years later, he had asymptomatic swelling in his right groin. Local recurrence was suspected, and surgical resection of the tumor with a sufficient surgical margin was performed. Pathological diagnosis was well-differentiated liposarcoma, sclerosing type. Ten cases of recurrent spermatic cord liposarcoma, including the present case, have been reported in Japan. Because of the possibility of local recurrence, spermatic cord liposarcoma needs strict and long-term follow up.     

Liposarcoma of the spermatic cord associated with rectum cancer: a case report

We report a case of liposarcoma of the spermatic cord associated with rectum cancer. A 78-year-old man visited our hospital with a complaint of painless left inguinal mass. He also showed constipation and bloody bowel discharge, rectum cancer was diagnosed by further evaluation. Ultrasonography, computed tomography and magnetic resonance imaging revealed a 2 x 4 x 6 cm mass in the left spermatic cord. Left high orchiectomy for the left inguinal tumor and Hartmann's procedure for rectum cancer was performed. Histologically, the mass in the left spermatic cord was well differentiated liposarcoma and rectum cancer was poorly differentiated adenocarcinoma. He died from rectum cancer with no evidence of recurrence of liposarcoma of the left spermatic cord after follow up for 6 months.     

A case of liposarcoma of spermatic cord

An 84-year-old male was referred to our hospital with the chief complaint of a painless inguinal mass. An elastic hard mass was palpable in the right inguinal region next to the spermatic cord. Ultrasonography and computed tomography showed an inguinal homogeneous mass which was slightly enhanced. Since the operation appearance indicated the tumor was arising from the right spermatic cord, right radical orchiectomy was performed. Histopathological examination revealed a well-differentiated liposarcoma of the right spermatic cord. This is the 70th case of liposarcoma of the spermatic cord reported in Japan.     

Liposarcoma of the spermatic cord: a case report

Objective

The aim of the article is to summarize experience in the pathology, diagnosis and treatment of spermatic cord liposarcoma (SCL).

Methods

The clinical data of a patient with liposarcoma of the spermatic cord was reviewed in combination with related literature.

Results

A 24-year-old male presented with a 1-year history of a mass in the right hemiscrotum. The tumor was resected and right inguinal orchidectomy was performed. The tumor had not recurred after 6 months follow-up.

Conclusion

Spermatic cord liposarcoma (SCL) is a rare medical condition and it is therefore difficult to establish guidelines for treatment, diagnosis and prognosis. Radical orchidectomy with wide local excision of the mass is the recommended therapy, while adjuvant radiotherapy may be considered in intermediate or high-grade tumors and recurrent liposarcomas. The role of chemotherapy is not well-defined.     

Liposarcoma of the spermatic cord masquerading as an incarcerated inguinal hernia

We present a rare case of liposarcoma of the spermatic cord. There are only 61 reports in the literature. The presenting complaint is usually a painless bulge in the inguinal or scrotal region. Our patient presented with a new-onset inguinoscrotal swelling that was misdiagnosed preoperatively as an incarcerated indirect hernia. The treatment for a spermatic cord liposarcoma is radical orchiectomy with high ligation of the cord. Radiation therapy is recommended in addition to surgery in situations with evidence of tumor with propensity for more aggressive behavior (i.e., high-grade tumor, lymphatic invasion, inadequate margin, or recurrence). The current literature, diagnosis, and management of malignant tumors of the spermatic cord are reviewed.     

A case of dedifferentiated liposarcoma of the spermatic cord

We report a case of dedifferentiated liposarcoma of the spermatic cord. A 79-year-old man was referred to our hospital with the chief complaint of a painless right scrotal swelling. A hard mass was palpable beside the soft mass which was suspected of lipoma or liposarcoma, and under this mass there was right testis. Therefore, we performed a right radical orciectomy. Histopathological diagnosis was dedifferentiated liposarcoma of the spermatic cord. Dedifferentiated liposarcoma of the spermatic cord was rare, and preoperative diagnosis was difficult.     

Liposarcoma of the spermatic cord

Primary malignant tumors of the spermatic cord are rare. We report a caseof paratesticular liposarcoma and discuss the prognosis of this neoplasmand its therapeutic implications.