Comparison of the complication rates between first and second (repeated) lengthening in the same limb segment

The purpose of this study is to compare the incidence and types of complications in children who are undergoing first and second (repeated) lengthenings of the same bone. This is a retrospective review of 11 children (12 limbs) who underwent limb lengthenings of the same bone twice. There were 7 femoral and 5 tibial repeated lengthenings. Diagnoses included congenital femoral deficiency or proximal femoral focal deficiency in 6 patients, fibular hemimelia in 2, achondroplasia in 2, and tibial hypoplasia in 1. Mean age was 8.5 years for the first lengthening and 11.5 years for the second lengthening. There were 2.2 complications per lengthening for the first procedure and 1.5 for the second lengthening. There were 5 major and 22 minor complications for the first lengthening and 1 major and 17 minor complications for the second lengthening, none of these data were found to be statistically different. The healing index was 1.3 +/- 0.43 months per cm first lengthening and 2.2 +/- 1.7 cm for the second lengthening. This study did not demonstrate a significantly higher rate of complications with repeated lengthening of the same limb, although the time in the fixator for the second lengthening was longer and the degree of lengthening less.     

Long-term results of lower limb lengthening by physeal distraction

Of the many methods of limb elongation, lengthening by physeal distraction is among the newest. The goal of this study was to estimate the long-term results of femoral and tibial lengthening by epiphyseal distraction. The authors examined 40 patients who underwent 24 femoral and 16 tibial lengthenings. The average follow-up period was 9.6 years. An average of 4.6 cm of femoral lengthening and 4.7 cm of tibial lengthening was achieved. The femoral healing index was 38.1 days/cm and the tibial healing index was 35.7 days/cm. After lengthening the epiphyseal cartilage started to function in all patients, and premature growth cartilage fusion was not observed during follow-up. Complications occurred in eight patients during femoral lengthening and in four during tibial lengthening. The authors suggest that physeal distraction is a good method for moderate and simple limb lengthening. Particular care should be applied to knee joint function, especially during femoral lengthening.     

The effect of tibial diaphyseal lengthening on the longitudinal growth of the tibia

Limb lengthening by tibial callotasis is usually performed in the metaphysis but may cause growth inhibition. Is diaphyseal lengthening more advantageous? Sixteen immature rabbits underwent 30% diaphyseal lengthening by tibial callotasis. The tibial length was measured on radiographs at the end of the distraction period and after an additional 5 weeks. The proximal and distal growth plates were assessed histomorphometrically. Osteotomy stimulated tibial elongation; however, combined with diaphyseal lengthening the stimulation was suppressed resulting in longitudinal growth that matched the control side. In longer lengthenings of limbs diaphyseal callotasis may be more advantageous than metaphyseal by not inhibiting longitudinal growth.     

Femoral and tibial lengthening by the Wagner method

This article represents a review of the author's experience with the Wagner lengthening device. Forty patients between 6 and 20 years of age underwent 44 lengthenings of the lower extremity by Wagner's technique (34 femoral and 10 tibial) between February 1977 and January 1999. Shortening was congenital in origin in 24 patients. Lengthening achieved averaged 5.69 cm for the femur and 4.3 cm for the tibia. No complication was observed in 50% of the lengthenings (category I). At least one complication modified the program and necessitated further surgery and general anesthesia in 45.45% of lengthenings (category II). The program was not completed in one patient and complications resulted in a sequela in another patient, representing 4.54% of lengthenings (category III). Twenty-one of the 22 lengthenings without complication were at the femur. Complications were more frequent in patients with a congenital origin. Many complications but no disastrous problems were encountered. Lengthening is better tolerated in children older than 10 years of age. Thirty-nine patients completed their program and were left with less than 2.5 cm discrepancy at the end of growth. The average follow-up was 8.10 years.     

Long-term results of lower limb lengthening by the Wagner method

Methods of limb lengthening have been continuously modified. The construction of an apparatus for gradual bone distraction was a great improvement. The aim of this study was to evaluate the long-term results of lower limb elongation using the Wagner technique. Between 1983 and 1989, 45 patients underwent surgery in the authors' institution. There were 31 femoral and 15 tibial lengthenings. The operation and lengthening procedure were performed according to the rules published by the method's author. The intended amount of lengthening was achieved in 80% of patients during tibial elongation and in only 52% during femoral elongation because of many problems, obstacles, and complications during treatment. A significant percentage of improper (deficient or irregular) new bone formation led to femoral malunion in three patients and to tibial and femoral delayed bone consolidation in six patients. Fast distraction produced great forces on the surrounding joint surfaces, resulting in a limited range of motion and joint stiffness. The Wagner technique does not seem to be effective and is associated with a long duration of treatment and some complications impairing the function of the limb.     

Simultaneous ipsilateral femoral and tibial lengthening with the Ilizarov method.

Eight pediatric patients who underwent nine simultaneous ipsilateral femoral and tibial lengthenings with the Ilizarov external fixator were reviewed. The patient's demographics, diagnoses, corticotomy levels, mechanical axes, healing indices, amounts of lengthening, and complications were recorded. The patients' average age was 8 years 10 months (5 years 4 months-15 years 10 months) with an average follow-up of 49 months (30-88 months). The percentage of femoral lengthening averaged 16.7% (8-23%) with an average healing index of 28 days/cm (20-38 days/cm). The percentage of tibial lengthening averaged 18% (9.6-23.6%) with an average healing index of 29 days/cm (1940 days/cm). Four complications in three patients occurred as a direct result of the lengthening process. Three of the complications involved soft-tissue contractures, which were each successfully treated with one additional surgical procedure, whereas the fourth complication involved poor bone regeneration and required bone grafting and additional immobilization.     

The effects of limb lengthening on growth

The purpose of this study was to determine the effects of limb lengthening on the rate of growth of the lengthened limb. The rate of growth of the lengthened and control (contralateral) limb segment were determined radiographically pre- and postoperatively in 19 skeletally immature patients (20 limbs). There were 13 femoral and seven tibial lengthenings. The mean age at the time of lengthening was 9.4 years (range 4.2-12.3). The limbs were lengthened by a mean of 6.7 cm (24%). Mean follow-up was 3.6 years. No significant difference was found between the change in the rate of growth of the lengthened and control limb (P=0.59). This was true for both the femur and the tibia, when analyzed separately. This study indicates that the change in the rate of growth between the lengthened and control limbs did not vary significantly in our patient group.     

Lower extremity lengthening by Wagner's method and by callus distraction

Fifty-three patients underwent 64 lengthenings of the femur or tibia by the Wagner technique or by the callus distraction method. Thirty-six femoral and 28 tibial segments were lengthened. Simultaneous lengthening of the femur and tibia was performed in seven limbs. Three segments underwent repeat lengthenings. The average length gained by the Wagner method was 5.1 cm in the femur and 5.4 cm in the tibia. Length gains by callus distraction were 4.9 cm in the femur and 4.5 cm in the tibia. Complication rates were fewer and less severe with callus distraction. The number of operations, days of hospitalization, and length of total treatment were less in patients operated on with the callus distraction method than in those who underwent the Wagner technique.     

Femoral lengthening over elastic stable intramedullary nailing in children using the monolateral external fixator

The authors report preliminary results of femoral lengthening performed with monolateral external fixation over elastic stable intramedullary nailing in children. Seven femoral lengthenings were performed in six patients, at a mean age at surgery of 6.6 years (range 1.5–12 years). All lengthenings were performed due to limb length discrepancy (congenital hypoplasia in four patients, growth arrest secondary to neonatal infective osteoarthritis in one, type II sacral agenesis in one). In six cases the elastic nails realised a bipolar ascending construct, in one case a descending construct. Cases were reviewed at a mean time from removal of external fixator of 34.2 months (range 15–75 months). The mean lengthening obtained was 4.8 cm (range 3.8–6.0 cm). Mean consolidation index was 42.9 days/cm. No case of axial deviation requiring surgery and no case of deep infection were recorded. No case of fracture of the regenerate occurred after removal of the external fixator. There were two premature consolidations requiring mobilisation under general anaesthesia, and a case of failure of consolidation requiring surgery. The technique reported provides indisputable biomechanical advantages, particularly increasing stability at the site of osteotomy. The characteristics of implants make this method ideal for lengthenings in children.     

Results of leg lengthening using Wagner's technique

Nineteen leg lengthenings by Wagner's technique were reviewed. Average patient age was 13 years (range, 8-18 years). The gain averaged 3.9 cm (range, 1.1-10 cm). Complications were prolonged treatment period (9 cases), metal-work failure (6), loss of gain (5), malunion (6), fracture (5), deep infection (2), and joint problem (6). The osteogenesis in the elongation gaps affected the results. No callus formation by 40 days after osteotomy and no bridging callus by the end of elongation period were warning signs of poor osteogenesis. All tibial lengthenings and femoral lengthenings of more than 5 cm or 13% of the original length were at risk of poor osteogenesis. Proper stabilization and bone grafting were the most effective measures for poor osteogenesis. Currently, Wagner's technique is not the treatment of choice because new techniques with fewer complications are available. However, Wagner's technique is useful in the cases to which the new procedures are not applicable.     

Selective soft tissue release preserves growth plate architecture during limb lengthening

Although distraction osteogenesis has proven successful in children, concerns remain regarding potential growth inhibition of the lengthened limb. Twenty-one 8-week-old New Zealand White rabbits underwent a unilateral 40% tibial lengthening with the contralateral tibia as control. The animals were divided into Achilles tendon release and non-release groups. Radiographs and histomorphometric analysis of the proximal tibial growth plate was performed 5 and 10 weeks after distraction. The corrected length of tibias without tenotomy was significantly shorter than the contralateral controls, whereas those with tenotomy were statistically equivalent to the contralateral control tibias. Histologically, the operated limbs without tenotomy showed a significant decrease in thickness and loss of cellular architecture of the proximal tibial growth plate compared with the tenotomy groups, which were of near-normal appearance. A concomitant tendo Achilles lengthening performed with 40% tibial lengthening preserves proximal tibial growth plate architecture in this model.     

Lower limb lengthening by a modified Wagner technique

A series of 50 patients who underwent femoral and tibial lengthenings using the Wagner apparatus is reviewed. Satisfactory gains in leg length with an acceptably low complication rate were achieved. Both substitution of cortical osteotomy for complete osteotomy and delaying of distraction increased callus formation. The particular problems of lengthening the congenital short femur and tibia are discussed.     

Limb lengthening and deformity correction with externally controlled motorized intramedullary nails: evaluation of 50 consecutive lengthenings

Background and purpose — Limb lengthening with an intramedullary motorized nail is a relatively new method. We investigated if lengthening nails are reliable constructs for limb lengthening and deformity correction in the femur and the tibia.

Patients and methods — 50 lengthenings (34 Precice and 16 Fitbone devices) in 47 patients (mean age 23 years [11–61]) with ≥12 months follow-up are included in this study. 30 lengthenings were done due to congenital and 20 because of posttraumatic deformity (21 antegrade femora, 23 retrograde femora, 6 tibiae). Initial deformities included a mean shortening of 42?mm (25–90). In 15 patients, simultaneous axial correction was done using the retrograde nailing technique.

Results — The planned amount of lengthening was achieved in all but 2 patients. 5 patients who underwent simultaneous axial correction showed minor residual deformity; unintentionally induced minor deformities were found in the frontal and sagittal plane. The consolidation index was 1.2 months/cm (0.6–2.5) in the femur and 2.5 months/cm (1.6–4.0) in the tibia. 2 femoral fractures occurred in retrograde femoral lengthenings after consolidation due to substantial trauma. There were 8 complications, all of which were correctable by surgery, with no permanent sequelae.

Interpretation — Controlled acute axial correction of angular deformities and limb lengthening can be achieved by a motorized intramedullary nail. A thorough preoperative planning and intraoperative control of alignment are required to avoid residual and unintentionally induced deformity. In the femur relatively fast consolidation could be observed, whereas healing was slower in the tibia.     

Optimum ratio of distraction in double level tibial lengthening

The authors reviewed 43 double level tibial lengthenings by Ilizarov technique in 34 consecutive patients (6-31 years old), and investigated the factors affecting regenerate bone healing to determine the optimum ratio of distraction rate or magnitude of lengthening at the proximal and distal osteotomy sites. Length gain averaged 6.1 cm (range, 2.5-12.3 cm), equivalent to a 28% increase of the segment. The variables investigated included age, gender, concomitant deformity correction, etiology, and the amount of length gain. The healing index averaged 1.8 months per centimeter proximally and 2.8 months per centimeter distally. Age and the amount of length gain affected the healing index at proximal and distal lengthening sites. However, the proximal to distal healing index ratio, which averaged 0.72, was not affected by any parameters investigated. This study suggests that to minimize external fixation treatment time, the distraction rate, or amount of length gain, of the distal osteotomy site should be approximately 3/4 that of the proximal site in the double level tibial lengthening.     

Ilizarov technique. Results and difficulties.

Of 100 cases treated by the Ilizarov method, 91 patients were reviewed from February 1985 to March 1990. There were 32 tibial fractures (29 open) and 21 nonunions (nine infected). There were 47 cases of limb lengthening (28 tibia and 19 femur). The results were as follows: good, 83%; fair, 13%; and poor, 4%. Slight and intermittent pain in some wire of the device was frequent (69%). Average bone healing time in tibial fractures was 4.95 months and 5.83 months in tibial nonunions. In bone-lengthening operations, the average lengthening index in the tibia was 1.02 months/cm (lengthenings ranged from 3 cm to 10 cm, with a mean of 5.71 cm), whereas in the femur, the average lengthening index was 1.14 months/cm (lengthenings ranged from 3 cm to 7 cm, with a mean of 5.34 cm). Manually-tensed wires produced frequent problems (24.5%), whereas wire tensed by the dynamometric tensioner produced problems in only 7.8% of the cases. Despite good results, the Ilizarov technique requires adequate training to reduce an overall complication rate (approximately 30%).     

Metatarsal lengthening in congenital brachymetatarsia: one-stage lengthening versus lengthening by callotasis.

We retrospectively reviewed and compared the outcomes of 15 one-stage metatarsal lengthenings with intercalary bone graftings in 10 patients with those of nine metatarsal lengthenings by callotasis in five patients younger than 15 years. In the one-stage lengthening group, the diaphyseal osteotomy site was gradually distracted intraoperatively for 20-30 min to relax the surrounding soft tissues. In the callotasis group, lengthening was achieved with mini-Orthofix M-100. There was little difference in the outcomes between the two groups in terms of length gain, percentage increase, and complications. However, the period to achieve bony consolidation was longer in the callotasis group (2.7 months/cm) than in the one-stage lengthening group (1.5 months/cm). No case of neurovascular impairment was found in both groups.     

Operative lengthening of the lower extremity and associated psychological aspects: the Children's Hospital experience

Twenty-two patients underwent 23 femoral and tibial lengthenings by the Wagner technique from 1977 to 1987. Average length gained was 5.8 and 5.2 cm, respectively. Long hospitalization in addition to multiple operative procedures and a high complication rate created a significant psychological impact. Fourteen of 22 patients experienced psychological problems, primarily adjustment disorders, all of which resolved without long-term sequelae. Parental/family and nursing staff support were identified as the most important during the lengthening process. Advances in limb lengthening techniques may lessen the overall impact of this procedure, but preoperative psychological preparation is important.     

Back pain and arthralgia before and after leg lengthening: 75 patients questioned after 6 (1-11) years

We performed 100 lengthenings of the lower extremities In 85 patients from 1980 to 1991, using three different surgical techniques. 6 (1-11) years after lengthening 75 ol these patients with a preoperative leg length inequality of 6 (3-14) cm were clinically and radiographically assessed, and replied to a questionnaire on pre- and postoperative complaints of low back pain and pain from the joints of the lower extremities.

Patients 15 years of age or younger at surgery had few complaints. Before lengthening, 18 patients suffered from severe low back pain compared with 6 at follow-up. Complaints from the joints of the lower extremities were less common and the effect of lengthening on these symptoms was minor. The ability to work, walk and to perform recreational activities was improved. 60 patients were satisfied with the result of the lengthening.     

Foot and Ankle Function after Tibial Overlengthening

Lengthening the tibia more than 25% of its original length can be indicated for proximal femoral deficiency, poliomyelitis, or femoral infected nonunion. Such lengthening of the tibia can adversely affect the ankle or foot shape and function. The present study aimed to assess the effect of tibial lengthening of more than 25% of its original length on the foot and ankle shape and function compared with the preoperative condition. This was a retrospective study of 13 children with severe proximal focal femoral deficiency, Aitken classification type D, who had undergone limb lengthening from June 2000 to June 2008 using Ilizarov external fixators. The techniques used in tibial lengthening included lengthening without intramedullary rodding and lengthening over a nail. The foot assessment was done preoperatively, at fixator removal, and then annually for 3 years, documenting the range of motion and deformity of the ankle and subtalar joints and big toe and the navicular height, calcaneal pitch angle, and talo-first metatarsal angle. At fixator removal, all cases showed equinocavovarus deformity, with decreased ankle, subtalar, and big toe motion. The mean American Orthopedic Foot and Ankle Society score was significantly reduced. During follow-up, the range of motion, foot deformity, and American Orthopedic Foot and Ankle Society score improved, reaching nearly to the preoperative condition by 2 years of follow-up. The results of our study have shown that tibial overlengthening has an adverse effect on foot and ankle function. This effect was reversible in the patients included in the present study. Lengthening of more than 25% can be safely done after careful discussion with the patients and their families about the probable effects of lengthening on foot and ankle function.     

Callus formation in femur and tibia during leg lengthening:7 patients examined with DXA

We examined the callus formation during leg lengthening in 7 achondroplastic patients who underwent 3 bilateral femoral and 4 bilateral tibial lengthenings. Bone mineral content and bone mineral density (BMD) in the lengthened callus space were evaluated every 1 or 2 weeks for 10 weeks after the start of distraction using dual energy X-ray absorptiometry.

The mean rate of callus mineralization in femurs (0.64 g/wk) was higher than in tibias (0.22 g/wk). The mean BMD at 10 weeks after the start was 0.35 g/ cm² in the femur and 0.14 g/cm² in the tibia. Different rates of callus formation in different kinds of long tubular bones have not been reported previously.