自体腓骨移植治疗桡骨远端骨巨细胞瘤复发

目的探讨自体近端腓骨移植重建在桡骨远端骨巨细胞瘤临床治疗中的应用及效果。方法对4例桡骨远端骨巨细胞瘤复发患者在行桡骨远端瘤段切除的同时,行自体近端腓骨移植重建手术。结果患者随访27～50个月,疼痛症状消失,骨愈合时间5～9个月,平均6.5个月,无移植骨吸收和骨折,腕关节功能握持力为对侧手的55%(40%～80%),背伸活动度可达对侧50%(10%～80%),掌屈达40%(15%～70%),无神经血管损伤症状,恢复正常工作劳动。所有患者均未出现骨巨细胞瘤的复发及肺转移。结论桡骨远端骨巨细胞瘤经广泛切除后,用自体近端腓骨移植进行保肢治疗,可较好地保留腕关节功能,是一种有效的治疗方法。     

桡骨远端骨巨细胞瘤28例外科治疗

目的：总结我院自1995年至今收治桡骨远端骨巨细胞瘤28例手术治疗及疗效。方法：采用2种不同的手术方式对桡骨远端骨巨细胞瘤进行治疗。结果：刮除植骨、骨水泥充填术后复发率为22％,而游离自体腓骨移植病例无复发。结论：瘤段切除、腓骨近端移植腕关节重建治疗桡骨远端骨巨细胞瘤复发率较传统刮除植骨、骨水泥充填术为低,可以很好的重建腕关节功能、取得满意的临床效果。     

游离自体腓骨移植并腕关节成形术治疗桡骨远端骨巨细胞瘤

[目的]回顾分析游离自体腓骨移植并腕关节成形术治疗桡骨远端骨巨细胞瘤的临床疗效。[方法]共纳入本院2008年8月～2016年12月收治的桡骨远端骨巨细胞瘤患者22例,采用自体腓骨移植修复肿瘤切除后骨缺损,随访记录复发、转移、骨愈合时间、关节脱位、患侧握力及腕关节功能等情况。[结果]本组病例术后平均随访(73.18±26.12)个月,1例局部复发,无远处转移病例;平均骨愈合时间(8.45±2.86)个月;3例出现下尺桡关节半脱位;术后握力平均恢复至健侧的72%。腕关节功能评价:背伸平均(44.77±9.22)°,掌屈(52.00±6.22)°,桡偏(16.50±3.28)°,尺偏(18.73±3.80)°。术后功能对比术前差异均有统计学意义(P<0.05)。[结论]游离自体腓骨移植并腕关节成形术是修复桡骨远端骨巨细胞瘤切除术后骨缺损的一种可靠选择。     

吻合血管的游离腓骨移植在桡骨远端骨巨细胞瘤治疗中的应用

目的评价应用显微外科技术,采用肿瘤段桡骨切除,吻合血管保留腓骨小头的自体游离腓骨移植治疗桡骨远端骨巨细胞瘤的疗效。方法行桡骨远端瘤段切除,用带血管的自体近端腓骨移植,修复桡骨缺损并重建腕关节,术后就放射学及功能评价内容进行随访。结果临床应用12例,术后平均随访48个月,均无局部复发,移植骨愈合良好,平均愈合时间为3·5个月。主观满意度为优良,1例最终行关节固定术。重建腕关节活动范围掌屈20°~40°,背伸30°~60°,尺偏20°~40°,桡偏15°~20°。握力是健侧的40%~85%,无腕关节不稳和畸形。腕关节功能评价采用Enneking标准,优2例,良8例,一般2例。结论桡骨远端骨巨细胞瘤经广泛切除后,用自体吻合血管的带腓骨小头游离腓骨移植治疗,既彻底切除了骨肿瘤,又保存了患侧上肢,同时较好地保留腕关节功能,是一种有效的方法。     

吻合血管的近段腓骨移植重建肩腕关节

目的 探讨带血管蒂的近段腓骨移植重建肩、腕关节炎的疗效。方法 对近端肱骨和桡骨远端骨巨细胞瘤病例彻底切除瘤段骨及周围反应组织,采用带血管蒂的游离近段腓骨移植重建肩关节和腕关节。结果 经术后6个月－2年随访,2例重建肩、腕关节外观和功能恢复良好,肿瘤无复发。结论 带血管蒂近段腓骨移植是治疗肱骨近端和桡骨远端肿瘤切除后骨缺损和重建肩、腕关节的理想方法。     

腓骨近端移植治疗桡骨远端骨巨细胞瘤:关节融合与成形的比较

[目的]回顾性比较研究桡骨远端骨巨细胞瘤切除后采用腓骨近端移植行腕关节成形术和腕关节部分融合术的临床疗效。[方法]2006年2月~2012年5月,采用桡骨远端瘤段切除自体腓骨移植重建腕关节方法治疗16例桡骨远端Ⅱ、Ⅲ级(Campanacci分级)骨巨细胞瘤患者。男8例,女8例,年龄19~55岁,平均35.40岁。病程1个月~2年,主要症状为关节疼痛、肿胀及活动受限。9例行部分腕关节融合术,7例行腕关节成形术。[结果]术后切口均一期愈合。所有患者均获随访,随访时间4.00~10.20年,平均6.40年。1例融合病例出现腓骨-舟月骨界面不愈合,排除出该研究。随访期间所有病例肿瘤无复发。融合术病例:腕关节屈伸(55.63±6.78)°,前臂旋转(126.25±14.58)°,平均握力为对侧的(75.14±5.74)%,MSTS评分平均为(25.5±0.76)分。成形术病例:屈伸(72.86±15.24)°;前臂旋转(140±14.72)°,平均握力为对侧的(60.62±11.83)%,MSTS评分平均为(25.86±1.46)分。前臂旋转功能方面两组差异无统计学意义;腕关节屈伸活动成形组优于融合组,而手腕握力融合组优于成形组,差异有统计学意义;但两组MSTS评分差异无统计学意义。[结论]瘤段切除自体腓骨近段移植重建腕关节是治疗桡骨远端骨巨细胞瘤的良好方法,腕关节成形术和腕关节部分融合术都能保留一定的腕关节功能,都是安全、有效的重建方式。应根据患者的实际情况作出个性化选择。     

膝关节融合治疗股骨远端侵袭性骨巨细胞瘤

目的：探讨应用自体腓骨移植联合膝关节融合治疗股骨远端侵袭性骨巨细胞瘤的应用及临床效果。方法：自2007-2009年对5例股骨远端侵袭性骨巨细胞瘤（Campanacci Ⅲ级）行整块切除术后骨缺损,采用游离腓骨移植联合钢板内固定行膝关节融合术重建下肢功能。结果：所有患者随访20～80个月,疼痛症状消失,MSTS评分21～27分,骨愈合时间6—18个月,无移植骨吸收和骨折,恢复正常工作劳动。所有患者均未出现病变复发及肺转移。结论：肿瘤整块切除联合腓骨移植膝关节融合术是治疗股骨远端侵袭性骨巨细胞瘤的一种良好选择。     

吻合血管腓骨小头移植重建治疗桡骨远端骨巨细胞瘤疗效研究

[目的]探讨骨巨细胞瘤患者在桡骨远端肿瘤切除后,通过吻合血管腓骨小头移植的方式修复骨缺损的疗效和术后腕关节恢复情况。[方法]选择2008年2月~2013年2月于本院进行骨巨细胞瘤切除术后,以吻合血管腓骨小头方式修复桡骨远端骨缺损的51例患者。随访并记录术后一般情况,如术后切口愈合情况,移植骨成活与否,骨愈合时间,肿瘤复发转移情况等。根据腕关节和前臂活动情况、Krimmer评分评估腕关节功能。[结果]所有患者切口均Ⅰ期愈合,患者腓骨小头都顺利成活,骨愈合时间平均(15.1±5.8)周。随访结果显示,腕关节和前臂活动与术前相比均显著改善(P0.05)。随访期间所有患者骨肿瘤无复发且无肺转移。根据Krimmer评分评价术后腕关节功能,优良率较高。[结论]吻合血管腓骨小头移植重建治疗桡骨远端骨巨细胞瘤疗效较好,值得临床推广与应用。     

上肢骨肿瘤切除后的自体骨移植重建

目的探讨应用自体骨移植对上肢骨肿瘤切除后的骨缺损修复重建的效果。方法1998年8月～2004年3月，收治上肢骨肿瘤切除后的骨缺损16例。男8例，女8例。年龄7～45岁。经病理确诊，肱骨近端尤文肉瘤和骨肉瘤各1例；肱骨远端尤文肉瘤2例；桡骨远端骨巨细胞瘤8例，高分化软骨肉瘤2例，恶性纤维组织细胞瘤和骨肉瘤各1例。2例肱骨近端肿瘤行自体锁骨代肱骨；2例肱骨远端肿瘤行自体腓骨代肱骨；12例桡骨远端肿瘤中，1例行自体髂骨移植，11例行自体腓骨代桡骨进行重建。采用MSTS系统进行术后功能评价。结果2例肱骨近端自体锁骨移植患者分别随访36个月和12个月，术后保持部分肩关节前屈和后伸功能，但外展功能丧失；MSTS评分分别为23分和22分。2例肱骨远端自体腓骨移植患者分别随访4个月和6个月，肘关节功能良好，移植骨连接处已经出现骨愈合；MSTS功能评分分别为24分和19分。12例桡骨远端自体骨移植患者中11例随访6～75个月，功能良好，无明显并发症；1例髂骨植骨的桡骨远端骨巨细胞瘤术后3个月移植骨完全愈合，至今随访75个月，肿瘤无复发。MSTS功能评分18~27分，平均22．6分。结论自体骨移植在上肢骨肿瘤切除后骨缺损的重建，尤其是儿童的骨缺损重建中，是一种较好的方法。     

腓骨近段移植重建桡腕关节治疗桡骨远端骨巨细胞瘤

腓骨近段移植重建桡腕关节治疗桡骨远端骨巨细胞瘤刘志成，李德甫，李天方桡骨远端骨巨细胞瘤治疗比较困难，刮除植骨复发率高，瘤段切除植骨及桡腕关节融合可引起腕关节的功能活动丧失。近２０年来，我们采用瘤段切除，以含腓骨头的胖骨重建桡腕关节，治疗１０例桡骨远端...     

Reconstruction of distal radius by fibula following excision of grade III giant cell tumour: Follow-up of 18 cases

The purpose of this study was to evaluate the long-term results of vascularised fibular graft for reconstruction of the wrist after excision of grade III giant cell tumour in the distal radius. From January 1998 to September 2003, 18 patients with wrist defects due to distal radius grade III giant cell tumour resection were treated with vascularised fibular graft and were followed-up. The limb function was restored to an average 80% of normal function and bone union was achieved within six months in 18 patients with vascularised fibular graft. MSTS score averaged 25.6 and ranged between 21 and 29; Mayo wrist score averaged 56 with a range from 40 to 65. It is appropriate to use the head of the fibula as a substitute for the distal radius. The healing of vascularised fibular graft is very quick and without bone resorption. Thus, in the procedure for reconstruction and limb salvage after bone tumour resection of distal radius, the free vascularised fibular graft with fibular head is an ideal substitute.     

Giant cell tumors of the distal radius: resection: reconstruction by long avascular fibular graft (a case report)

Giant cell tumors (GCT) are locally aggressive tumors with a preference for epiphyses and metaphyses of long bones. They represent 5%-10% of all primary bone tumors. They affect mostly young adults between 20 and 40. Their origin remains uncertain. GCT is a purely lytic tumor, recurrent and can even lead to fracture. The distal radius is the third location after the distal femur and proximal tibia. Tumors are benign on histopathology, but "benign" lung metastases can sometimes be seen. Their treatment remains controversial because of the high rate of recurrence; oncological resection of the diseased bone segment with reconstruction reduces the rate of recurrence. Several techniques of resection and reconstruction of the wrist have been proposed. We report a case of giant cell tumor of the distal radius treated by resection and reconstruction by avascular fibular graft to a length of 12cm, and we evaluate the use of this reconstruction to salvage the wrist with this pathology.     

桡骨远端瘤段切除后单纯自体腓骨移植与吻合血管腓骨移植重建桡腕关节疗效比较

目的分析单纯自体腓骨移植与吻合血管腓骨移植在桡骨远端瘤段切除后修复桡骨远端缺损和重建桡腕关节远期效果.方法 1979年1月～2002年9月对15例桡骨远端肿瘤患者行瘤段切除后,6例行单纯自体腓骨移植,9例行吻合血管腓骨移植重建桡腕关节.随访1年,参照Enneking系统及国际肢体修复讨论会所制定的同种/带血管蒂骨移植的影像学评价方法,进行肢体功能、影像学及供区的功能评价.结果 8例吻合血管腓骨移植恢复肢体功能的80%,6个月内完成骨愈合;6例单纯自体腓骨移植恢复肢体功能的67%,其中4例移植骨在5 cm以内术后6个月骨愈合可,2例骨移植超过12 cm者愈合延迟,分别为13个月和16个月;1例术后2个月行肘下截肢术.结论应用腓骨头替代桡骨远端重建腕关节是合适的;吻合血管腓骨移植重建桡腕关节不受骨缺损长度影响,且植骨愈合率高、时间短,无骨吸收.可作为桡骨远端肿瘤手术治疗的一种有效手段.     

Resection-reconstruction arthroplasty for giant cell tumor of distal radius

Background:

Giant cell tumor (GCT) of the distal radius poses problems for reconstruction after resection. Several reconstructive procedures like vascularized and non-vascularized fibular graft, osteo-articular allograft, ceramic prosthesis and megaprosthesis are in use for substitution of the defect in the distal radius following resection. Most authors advocate wrist arthrodesis following resection of distal radius and non vascularized fibular graft. Here we have analyzed the results of aggressive benign GCTs of the distal radius treated by resection and reconstruction arthroplasty using autogenous non-vascularized fibular graft.

Materials and Methods:

Twenty-four cases of giant cell tumor of the distal radius (mean age 32 years, mean follow-up 6.6 years) treated by en-bloc resection and reconstruction arthroplasty using autogenous non-vascularized ipsilateral fibular graft with a minimum followup of two years have been included in this retrospective study. Nineteen cases were of Campanacci grade III and five were of Grade II recurrence. The mean resected length of the radius was 9.5 (8-12) cm. Routine radiographs and clinical assessments regarding pain, instability, recurrence, hand grip strength and functional status were done at regular intervals and functional results were assessed using (musculoskeletal tumor society) MSTS-87 scoring.

Results:

Early radiological union at host-graft junction was achieved at mean 12.5 weeks, (range 12-14 weeks) and solid incorporation with callus formation was observed in mean 29 weeks (range 28-32 weeks) in all the cases. Satisfactory range of motion (mean 63%, range 52-78%) of the wrist was achieved in 18 cases. Grip strength compared to the contralateral hand was found to be 67% (range 58-74%). Functional results were excellent in six cases (25%), good in 14 cases (58.3%) and four (16.7%) cases had fair results. Soft tissue recurrence was seen in one patient. The most commonly encountered complication was fibulo-carpal subluxation (10 cases, 41.7%).

Conclusion:

Resection of the distal radius and reconstruction arthroplasty with non-vascularized proximal fibular graft is useful in preserving the functional movement and stability of the wrist as well as achieving satisfactory range of movement and grip strength.     

吻合血管带腓骨头腓骨移植重建肩腔关节

目的：扩展活腓骨移植在骨肿瘤保肢手术中的应用,特别涉及关节端骨肿瘤保肢治疗的应用。方法：采用吻合血管带腓骨头的腓骨移植重建10例肱骨头周,5例桡骨远端骨肿瘤瘤段切除术后的肩、腕关节。结果：术后6个月所有腓骨移植段与受区骨端愈合良好,骨形态替代理想,重建后的肩、腕关节无论从外观或功能方面均获得较好的重建效果。结论：吻合血管带腓骨头的腓骨移植对肩关节肱骨端、腕关节桡骨端骨肿瘤保肢手术的关节重建中起到较好的替代作用。     

桡骨远端巨细胞瘤切除自体腓骨头移植重建的远期疗效观察

目的 观察桡骨远端巨细胞瘤切除后取自体腓骨头移植重建的远期疗效.方法 对1994年3月至2004年11月31例桡骨远端巨细胞瘤患者行肿瘤大段切除,取自体腓骨上段移植重建.其中男性12例,女性19例;年龄19～48岁,平均31岁.Campanacci分期Ⅲ期24例,Ⅱ期7例.采用吻合血管的腓骨移植6例,其余25例行单纯腓骨移植.对本组患者进行临床及影像学评估,测量患者腕关节活动度、前臂旋前及旋后的活动度,测量患肢的握力.分别以MSTS评分及Mayo腕关节评分系统评价上肢及腕关节功能.结果 随访时间41～169个月,平均86.3个月.吻合血管的腓骨移植骨愈合时间为3～9个月,平均5.1个月.单纯腓骨移植患者骨愈合时间为7～15个月,平均10.3个月.1例单纯腓骨移植患者术后出现骨不愈合.1例患者术后出现肿瘤局部复发,复发率为3.2%.5例患者术后出现桡腕关节脱位.患者术后腕关节活动度为背伸(67.3±9.4)°、掌屈(31.2±5.1)°、桡偏(14.1±4.7)°、尺偏(19.4±3.9)°、前臂旋前(33.8±6.6)°、前臂旋后(15.3±4.0)°.对桡腕关节成型的28例患者进行握力测量为15.5～52.1 kg,平均33.1 kg,占健侧握力的73%.MSTS评分为23～29分,平均25.5分,Mayo腕关节功能评分40～65分,平均56分.结论 取自体腓骨上端移植重建是治疗桡骨远端巨细胞瘤的有效方法,术后患者腕关节功能恢复理想.腕关节囊的重建对于维持桡腕关节的术后稳定具有重要意义.     

带血管蒂腓骨瓣移植重建CampanacciⅢ级桡骨远端骨巨细胞瘤切除术后桡腕关节的远期疗效

目的总结CampanacciⅢ级桡骨远端骨巨细胞瘤(giant cell tumor,GCT)瘤段切除后,采用带血管蒂自体腓骨瓣移植重建桡腕关节的远期疗效。方法2010年12月-2014年12月,收治10例CampanacciⅢ级桡骨远端GCT患者。其中男6例,女4例;年龄22~65岁,平均39.9岁。病程1.5~6.0个月,平均2.6个月。4例合并病理性骨折。肿瘤切除后桡骨远端骨缺损长度为6.0~12.5 cm,平均8.4 cm。采用自体腓骨瓣移植重建桡腕关节,6例吻合膝下外侧血管,4例吻合膝下外侧血管+腓血管双套血管蒂。结果术后切口均Ⅰ期愈合。患者均获随访,随访时间4.4~8.3年,平均6.0年。随访期间肿瘤无复发。末次随访时,腕关节活动范围:背伸25~85°,平均55.0°;掌屈15~40°,平均26.5°;桡偏5~25°,平均12.0°;尺偏10~30°,平均19.6°;前臂旋前5~90°,平均50.5°;旋后20~90°,平均66.5°。患侧握力达健侧60%~85%,平均75%。美国骨与软组织肿瘤协会(MSTS)评分为75%~90%,平均82.7%。X线片复查示移植腓骨瓣均愈合,愈合时间12~16周,平均14.1周;9例出现影像学并发症。结论CampanacciⅢ级桡骨远端GCT切除后,采用带血管蒂腓骨瓣移植重建桡腕关节,能够有效保留腕关节功能。     

吻合血管的腓骨近端移植修复桡骨远端骨肿瘤切除术后骨缺损

目的 评价吻合血管的腓骨近端移植修复桡骨远端骨肿瘤切除术后骨缺损的方法及治疗效果.方法 对12例桡骨远端骨肿瘤患者行桡骨远端切除,应用吻合血管的腓骨近端移植修复骨缺损并重建桡腕关节.术后对肢体功能及影像学进行评价.结果 12例患者均获随访,时间1～9年.腕关节平均活动度:掌屈30.3°±6.5°,背伸 52.1°±8.7°,尺偏 19.2°±3.6°,桡偏 12.3°±2.1°,旋前 32.1°±4.2°,旋后 21.2°±3.9°.按Enneking标准评价肢体功能:优4例,良6例,一般2例.移植腓骨均在3～6个月达到骨性愈合.5例出现不同程度的下尺桡关节分离,3例出现桡腕关节半脱位.肿瘤无复发.结论 吻合血管的腓骨近端移植是治疗桡骨远端骨肿瘤切除术后骨缺损的有效方法.     

Hernia mesh prevent dislocation after wide excision and reconstruction of giant cell tumor distal radius

Giant cell tumor(GCT) remains as major health problem. GCT which located at the lower end of the radius tends to be more aggressive. Wide excision and reconstruction of the wrist in stage 3 of distal radius GCT lesion is an optimal modality to prevent tumor recurrence. However, dislocation often occurs as its complication. We are reporting patient with GCT of distal radius treated with wide excision and reconstruction using nonvascularized fibular graft and the addition of hernia mesh. Circumferential non-absorbable polypropylene hernia mesh was applied, covered radioulnar joint and volar aspect of radius, and served as additional support to prevent dislocation. During five years and two months of follow-up, we found no dislocation in our patient. Furthermore, good functional outcome was obtained. Our finding suggests that the addition of hernia mesh after wide excision and reconstruction with nonvascularized fibular graft may benefit to prevent dislocation and provides an excellent functional outcome.