沙美特罗替卡松粉吸入剂联合太极拳锻炼对稳定期重度COPD患者的影响

目的 探讨沙美特罗替卡松粉吸入剂(舒利迭)联合太极拳锻炼对稳定期重度COPD患者的影响.方法 将稳定期重度COPD患者76例随机分组为观察组和对照组各38例,脱落6例,最终入组各35例.2组在常规治疗基础上,观察组给予沙美特罗替卡松粉吸入剂50 μg/500 μg吸入及太极拳锻炼.对照组只给予沙美特罗替卡松粉吸入剂50 μg/500 μg吸入.2组疗程均为6个月,并随访至少1年统计门诊及住院次数.结果 2组在肺功能、活动能力、生活质量方面均较前明显改善(P＜0.05),观察组免疫功能明显高于对照组(P＜0.05),门诊及住院次数明显低于对照组(P＜0.05).结论 沙美特罗替卡松粉吸入剂联合太极拳锻炼不仅能改善稳定期重度COPD患者的肺功能、活动能力和生活质量,还能提高患者免疫功能,减少门诊及住院次数.     

The efficacy of Tai Chi for depression: A protocol for systematic review and meta-analysis

Background:Depression is a commonly occurring and recurrent mental disorder cross the world. Tai Chi is a traditional Chinese mind-body exercise which could be used to treat mental disorders including depression. This study aimed to conduct a systematic review and meta-analysis to assess the efficiency of Tai Chi for patients with depression.Methods:This protocol follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses protocol statement. Literature will be searched at PubMed, EMBASE, Web of Science, Cochrane Library, China Biology Medicine Database, China National Knowledge Infrastructure, Technology Journal Database, and Wan Fang database from the start date to September 2021. The Review Manager 5.3 software will be used to manage literature. After literature screening, 2 reviewers will extract data from the respects of general information, methodology, and results. The data analysis will be conducted with Review Manager and Stata 16 software, and the publication bias and literature quality will be both evaluated.Results:The results will contain the evaluation of clinical efficacy of Tai Chi practice for depression, as well as the assessment of literature quality and publication bias.Conclusion:The current review will provide new evidence on whether and to what extent patients with depression can benefit from Tai Chi practice.Registration number: DOI: 10.17605/OSF.IO/AUDNQ (https://osf.io/audnq).     

Effect of Tai Chi on cardiac function in patients with myocardial infarction: A protocol for a randomized controlled trial

Background:Myocardial infarction is 1 of the most serious cardiovascular diseases. Early interventional therapy preserves the cardiac function of patients with myocardial infarction to the greatest extent, but it is far from meeting people''s need only limited to cardiac revascularization. It is also necessary to help patients improve their quality of life, exercise tolerance, and reduce the incidence of acute cardiac recurrence as much as possible. All these depend on cardiac rehabilitation (CR) are based on exercise. Early and correct CR helps to improve the patient''s heart function and improve living standards. Traditional Chinese exercise Tai Chi as an alternative form of CR has gradually become popular, but it lacks large samples and high-quality clinical studies to verify it. This study aims to explore the effect of Tai Chi on the cardiac function of patients with myocardial infarction, and to provide a strong basis for patients to choose which CR exercise.Methods:This is a prospective randomized controlled trial. 272 patients with myocardial infarction will be randomly divided into an experimental group and a control group according to 1:1, with 136 cases in each group. The control group: conventional treatment; the experimental group: increase Tai Chi exercise on the basis of the control group. Both groups will receive standard treatment for 24 weeks and will be followed up for 3 months. Observation indicators include: total effective rate, 6 minutes walking test, brain natriuretic peptide, left ventricular ejection fraction, the adverse reaction rate, etc. The data will be analyzed by using SPSS 25.0 software.Discussion:This study will evaluate the effect of Tai Chi on the cardiac function of patients with myocardial infarction. The results of this test will provide clinical evidence for patients to choose which CR exercise.Trial registration:OSF Registration number: DOI 10.17605/OSF.IO/QKWDP.     

传统哲学视角下太极运动对健康促进作用的研究

太极运动作为我国古老的武术活动,近年来在全民健身的热潮下越来越受到了人们的关注,因其缓慢而温和的特点深受中老年人的喜爱。本文运用文献资料法、逻辑分析法等,立足于传统哲学的研究视角,对太极运动的起源、哲学思想及潜在作用和对疾病的干预作用展开研究。研究认为,气是太极运动的核心,身心合一体现了自然平衡观的思想,反映了中国哲学的内涵。同时,太极运动具有促进身体健康、预防疾病的作用。     

太极拳运动对中老年男性抑郁和睡眠质量的影响分析

目的 探讨太极拳运动对中老年男性抑郁和睡眠质量的影响。方法 对太极拳发源地河南省温县陈家沟村40岁以上的常住居民进行练拳情况、抑郁、焦虑和睡眠质量相关调查,根据练拳情况分为练拳组188人,不练拳组209人。对两组数据进行统计分析。结果 练拳组的抑郁、焦虑和睡眠量表的得分均小于不练拳组,差异有统计学意义,t值依次为-2.11、-3.37、-2.88,均为P<0.05。多重线性回归分析显示练拳频率是焦虑(β=-0.22,P=0.038)、睡眠(β=-0.83,P=0.014)的主要影响因素。结论 太极拳运动对中老年男性抑郁和睡眠质量有一定改善作用,可作为中老年人群的一种运动方式在社区中积极推广。     

Vitamin D Treatment for the Prevention of Falls in Older Adults: Systematic Review and Meta‐Analysis

OBJECTIVES: To systematically review and quantitatively synthesize the effect of vitamin D therapy on fall prevention in older adults. DESIGN: Systematic review and meta‐analysis. SETTING: MEDLINE, CINAHL, Web of Science, EMBASE, Cochrane Library, LILACS, bibliographies of selected articles, and previous systematic reviews through February 2009 were searched for eligible studies. PARTICIPANTS: Older adults (aged ≥60) who participated in randomized controlled trials that both investigated the effectiveness of vitamin D therapy in the prevention of falls and used an explicit fall definition. MEASUREMENTS: Two authors independently extracted data, including study characteristics, quality assessment, and outcomes. The I² statistic was used to assess heterogeneity in a random‐effects model. RESULTS: Of 1,679 potentially relevant articles, 10 met inclusion criteria. In pooled analysis, vitamin D therapy (200–1,000 IU) resulted in 14% (relative risk (RR)=0.86, 95% confidence interval (CI)=0.79–0.93; I²=7%) fewer falls than calcium or placebo (number needed to treat =15). The following subgroups had significantly fewer falls: community‐dwelling (aged <80), adjunctive calcium supplementation, no history of fractures or falls, duration longer than 6 months, cholecalciferol, and dose of 800 IU or greater. Meta‐regression demonstrated no linear association between vitamin D dose or duration and treatment effect. Post hoc analysis including seven additional studies (17 total) without explicit fall definitions yielded smaller benefit (RR=0.92, 95% CI=0.87–0.98) and more heterogeneity (I²=36%) but found significant intergroup differences favoring adjunctive calcium over none (P=.001). CONCLUSION: Vitamin D treatment effectively reduces the risk of falls in older adults. Future studies should investigate whether particular populations or treatment regimens may have greater benefit.     

Lack of Effect of Tai Chi Chuan in Preventing Falls in Elderly People Living at Home: A Randomized Clinical Trial

OBJECTIVES: To evaluate the effectiveness of Tai Chi Chuan in fall prevention in elderly people living at home with a high risk of falling.
DESIGN: Randomized controlled trial.
SETTING: Two industrial towns in the western part of the Netherlands.
PARTICIPANTS: Two hundred sixty-nine elderly people (average age 77) living at home with a high risk of falling.
INTERVENTIONS: The intervention group received Tai Chi Chuan training for 1 hour twice a week for 13 weeks; the control group received usual care. Both groups received a brochure containing general information on how to prevent fall incidents.
MEASUREMENTS: Primary outcome was the number of falls over 12 months. Secondary outcomes were balance, fear of falling, blood pressure, heart rate at rest, forced expiratory volume during the first second, peak expiratory flow, physical activity, and functional status.
RESULTS: After 12 months, no lower fall risk in the Tai Chi Chuan group was observed than in the control group (adjusted hazard ratio=1.16; 95% confidence interval=0.84–1.60), and there were no significant intervention effects on the secondary outcome measures.
CONCLUSION: These results suggest that Tai Chi Chuan may not be effective in elderly people at a high risk of falling who live at home.     

Tai Chi for Chronic Illness Management: Synthesizing Current Evidence from Meta-Analyses of Randomized Controlled Trials

An umbrella review of systematic reviews and meta-analyses of randomized controlled trials (RCTs) was conducted to evaluate the existing evidence of Tai Chi as a mind-body exercise for chronic illness management. MEDLINE/PubMed and Embase databases were searched from inception until March 31, 2019, for meta-analyses of at least two RCTs that investigated health outcomes associated with Tai Chi intervention. Evidence of significant outcomes (P value < 0.05) was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.This review identified 45 meta-analyses of RCTs and calculated 142 summary estimates among adults living with 16 types of chronic illnesses. Statistically significant results (P value < 0.05) were identified for 81 of the 142 outcomes (57.0%), of which 45 estimates presenting 30 unique outcomes across 14 chronic illnesses were supported by high (n = 1) or moderate (n = 44) evidence. Moderate evidence suggests that Tai Chi intervention improved physical functions and disease-specific outcomes compared with nonactive controls and improved cardiorespiratory fitness compared with active controls among adults with diverse chronic illnesses. Between-study heterogeneity and publication bias were observed in some meta-analyses.