Fixation methods in sagittal split ramus osteotomy: a systematic review on in vitro biomechanical assessments

The aim of this systematic review was to assess the stability of rigid internal fixation (RIF) techniques in sagittal split ramus osteotomy (SSRO) based on in vitro biomechanical assessments, with particular interest in large mandibular advancements. In general, RIF methods can be divided into three groups: bicortical screws, miniplates, and a combination of the two. An electronic search of the PubMed, CINAHL, and Embase databases was performed, and studies published between January 2003 and March 2018 were screened for inclusion. Comparative studies with an in vitro experimental design, using biomechanical assessments to measure the stability of RIF methods in SSRO, were included. Of 104 unique studies identified in the initial search, 24 were included. Twenty-two of these 24 studies analyzed an advancement of the mandible of 7 mm or less. The use of a single four-hole or six-hole miniplate was less stable than the use of bicortical screws, hybrid techniques, double miniplates, or grid plates. Two studies analyzed advancements of 10 mm, for which two miniplates placed in parallel and a grid plate showed most stability. Although there was agreement between studies with regard to results, more biomechanical studies are required to quantify the stability of fixation methods in larger mandibular advancements.     

下颌支矢状劈开术与下颌管位置关系的应用解剖学研究

目的研究下颌管在下颌骨内的重要行径和位置关系。方法选用带软组织50具完整的头颈标本,分别在下颌第三磨牙后缘的垂直线、磨牙后三角尖至下颌角连线呈额状位锯开下颌骨,观察下颌管的解剖。结果下颌管是下颌骨的骨松质内形成较薄的骨密质骨管。下颌管在下颌骨第三磨牙后缘切面的位置靠内侧型占90%,中间型占10%;在连线切面的位置靠内侧型占84%,中间型占16%。结论了解下颌管在下颌骨内的重要毗邻关系,可以减少因下牙槽神经损伤造成口裂以下粘膜和皮肤的感觉障碍。     

双侧下颌升支矢状劈开截骨后退术对下颌骨宽度及形态的影响

目的通过对下颌前突患者行双侧下颌升支矢状劈开截骨后退术前后头颅正侧位定位片硬组织结构变化的洲量分析,评价手术对患者下颌骨宽度及形态的影响。方法选择1997年至2001年在我中心行双侧下颌升支矢状劈开术的下颌前突患者18例,男性9例,女性9例,平均年龄22．22岁,所有患者手术前、术后一周、术后一年拍摄静止位头颅正侧位定位片,在正位片上测量下颌骨宽度(Go-Go),并从头颅正侧位定位片上测量与下颌骨宽度变化有关的参数数值。结果①下颌骨宽度由107．30mm±5．84mm(术前)增加至109．24mm±5．72mm(术后一周)、109．31mm±5．66mm(术后一年),其中有4例宽度减小,1例保持不变。13例增加,②下颌骨宽度术前、术后一用、术后一年的方差分析结果表明差别有显著性。③分析表明下颌骨宽度变化与各参数变化之间没有线性相关。结论①下颌骨宽度在双侧下颌升支矢状劈开截骨术后较术前有轻微增大,但对容貌没有大的影响。②下颌骨宽度变化机制可能与颞下颌关节功能改变有关。     

Comparison of osseous healing after sagittal split ramus osteotomy and intraoral vertical ramus osteotomy

The sagittal split ramus osteotomy (SSRO) is generally associated with greater postoperative stability than the intraoral vertical ramus osteotomy (IVRO); however, it entails a risk of inferior alveolar nerve damage. In contrast, IVRO has the disadvantages of slow postoperative osseous healing and projection of the antegonial notch, but inferior alveolar nerve damage is believed to be less likely. The purposes of this study were to compare the osseous healing processes associated with SSRO and IVRO and to investigate changes in mandibular width after IVRO in 29 patients undergoing mandibular setback. On computed tomography images, osseous healing was similar in patients undergoing SSRO and IVRO at 1 year after surgery. Projection of the antegonial notch occurred after IVRO, but returned to the preoperative state within 1 year. The results of the study indicate that IVRO is equivalent to SSRO with regard to both bone healing and morphological recovery of the mandible.     

Surgical morbidities of sagittal split ramus osteotomy versus intraoral vertical ramus osteotomy for the correction of mandibular prognathism: a randomized clinical trial

The sagittal split ramus osteotomy (SSRO) and intraoral vertical ramus osteotomy (IVRO) are two common orthognathic procedures for the treatment of mandibular prognathism. This randomized clinical trial compared the surgical morbidities between SSRO and IVRO for patients with mandibular prognathism over the first 2 years postoperative. Ninety-eight patients (40 male, 58 female) with a mean age of 24.4 ± 3.5 years underwent bilateral SSRO (98 sides) or IVRO (98 sides) as part or all of their orthognathic surgery. IVRO presented less short-term and long-term surgical morbidity in general. The SSRO group had a greater incidence of inferior alveolar nerve deficit at all follow-up time points (P <  0.01). There was more TMJ pain at 6 weeks (P =  0.047) and 3 months (P =  0.001) postoperative in the SSRO group. The SSRO group also presented more minor complications, which were related to titanium plate exposure and infection. There were no major complications for either technique in this study. Despite the need for intermaxillary fixation, IVRO appears to be associated with less surgical morbidity than SSRO when performed as a mandibular setback procedure to treat mandibular prognathism.     

The stability of bilateral sagittal ramus osteotomy and vertical ramus osteotomy after bimaxillary correction of class III malocclusion

Introduction

The purpose of this retrospective cephalometric study was to compare the stability of bilateral sagittal split osteotomy (BSSO) with extra-oral vertical ramus osteotomy (VRO) after correction of class III malocclusion by means of bimaxillary orthognathic surgery.

Methods

The sample comprised 51 consecutively treated patients, 38 females and 13 males, with a mean age of 19.1 years. All had a one-piece Le Fort I osteotomy with maxillary advancement and mandibular setback. VRO was performed in 30 cases, and BSSO was performed in 21 cases. Lateral cephalograms were obtained before surgery, within 1 week of surgery and 1 year after surgery.

Results

The mean forward movement of the maxilla was 5.6 mm in both groups (p < 0.001). The mean horizontal surgical change in the VRO group was 4.4 mm (p < 0.001), and in the BSSO group it was 5.4 mm (p < 0.001). In the VRO group, the horizontal relapse was 1.2 mm (p < 0.001), and in the BSSO group, it was 1.4 mm (p < 0.001).

Conclusion

There was no difference in the stability between the BSSO and VRO groups. The average relapse in the whole sample was 26% of the surgical movement.     

Position of the mandibular canal before and after bilateral sagittal split ramus osteotomy: a cone beam computed tomographic study

The aim of this study was to evaluate the position of the mandibular canal (MC) before and after bilateral sagittal split ramus osteotomy (BSSRO) using cone-beam computed tomography (CT), and to compare the position of the MC in Class II and Class III patients in the preoperative period. Patients were divided into two groups: Class II (n = 38) and Class III (n = 41). Measurements of the superior, inferior, buccal, and lingual distances of the MC in relation to the cortical bone were taken at three levels in the proximal segment of the mandible. Results were analysed using the Kruskal–Wallis test (p < 0.05). In the Class II group the superior distance of the MC at levels 2 and 3, and the inferior distance at level 3 significantly decreased after BSSRO. In the Class III group, no significant differences were found at any level, and the inferior distances at all levels were smaller preoperatively than those in the Class II group. In the Class II group the position of the MC altered in relation to superior and inferior cortical bone after BSSRO. However, the position of the MC remained stable in the Class III group. Our results also suggest a deeper cut in inferior cortical bone in Class III patients.     

Stability of fixation methods in large mandibular advancements after sagittal split ramus osteotomy: an in vitro biomechanical study

Sagittal split ramus osteotomy (SSRO) with large mandibular advancements is a common surgical procedure and could be indicated for patients with sleep apnoea. As a large variety of fixation methods is used for the stabilisation of SSRO, a biomechanical test model was used to analyse which fixation technique was most stable. For this in vitro study, 80 polyurethane hemimandibles with a prefabricated SSRO were used as substrates. Loads in Newtons were recorded at displacements of the mandibular incisive edge at 1 mm, 3 mm and 5 mm. The samples were divided into two groups: mandibular advancements of 10 mm and 15 mm. In both groups, four fixation techniques were used: (A) one four-hole miniplate; (B) two four-hole miniplates; (C) one four-hole miniplate plus one bicortical screw; and (D) three bicortical screws in an inverted-L arrangement. In group 1, three bicortical screws resulted in the best stability, and in group 2, two miniplates resulted in the best stability. The use of two miniplates did not show significant differences between both groups. Other fixation methods showed more stability with 10 mm advancements. This study therefore suggests that in SSRO with advancements exceeding 10 mm, the use of two miniplates is the optimal means of providing rigid fixation.     

下颌升支截骨手术相关下颌管解剖标志的多层CT测量研究

目的:应用多层CT影像测量下颌骨与升支矢状劈开截骨手术相关下颌管骨性解剖标志,为避免手术中损伤下齿槽神经血管提供指导。方法:选择60名正常成人下颌骨多层CT扫描图像,应用efilm1.94图像处理软件分别在第二磨牙远中的垂直线,磨牙后三角尖至下颌角连线及下颌孔下5 mm处取下颌骨断面,测量下颌管的解剖位置。结果:下颌管在下颌第二磨牙远中断面距颊侧骨面的距离为6.26±4.34 mm;在磨牙后三角尖至下颌角连线断面距颊侧骨面的距离为5.18±2.12 mm;在下颌孔下5 mm断面距颊侧骨面的距离为4.44±2.38 mm。结论:参照测量获得的解剖数据在术中能降低下齿槽神经血管损伤的发生率。     

下颌管定位与下颌支矢状骨劈开术后感觉神经障碍相关性的临床观察

目的 用CT扫描来确定下颌前突患者下颌支部下颌管的定位,并评价下颌管与颊侧骨皮质之间骨髓腔宽度与术后感觉神经障碍(NSD)之间的关系。方法 把通过下颌管最先形成的平面作为基础平面1,紧邻下颌第二磨牙远中与平面1相垂直作为平面5,二者角分线为平面3,平面1和3,3和5的角分线分别为平面2和4,共5个平面,在每一平面测量颊侧骨髓腔的宽度。以问卷的形式描述术后下牙槽神经分布区域的感觉改变。测量结果 采用SPSS13.0软件包进行统计学分析。用卡方检验评价骨髓腔宽度和术后NSD之间的关系。结果 颊侧骨髓腔宽度左右两侧无显著性差异(t=-0.871,P=0.384),其宽度的总体变化没有规律,在3、4层面距离最小,各层之间差异有显著性(F=2.795,P=0.017)。颊侧骨髓腔缺如(接触和融合型),在3和4层面出现几率较高。颊侧骨髓腔宽度为0的27侧100%发生术后NSD。未接触组63侧有14.3%发生术后NSD,两组间差异有显著性(χ2=25.941,P<0.05)。结论 颊侧骨髓腔的宽度是术后NSD的风险因子,当下颌管和颊侧骨皮质之间的骨髓腔宽度是0.9mm或更小时,NSD更容易发生,当颊侧骨髓腔缺失时,从外侧骨皮质中分离下牙槽神经十分困难。     

The different effects of intraoral vertical ramus osteotomy (IVRO) and sagittal split ramus osteotomy (SSRO) on mandibular border movement

Objectives: This study investigated the different effects of intraoral vertical ramus osteotomy (IVRO) and sagittal split ramus osteotomy (SSRO) on mandibular border movement.

Methods: The participants included 22 patients receiving IVRO and 22 patients receiving SSRO who were treated at Okayama University Hospital. Their mandibular border movement was evaluated in three dimensions with 6° of freedom using an optical recording system.

Results: A strong correlation between condylar and lower incisor movement was observed during maximum jaw protrusion and laterotrusion. Significant improvements in condylar and lower incisor movement were detected after orthognathic surgery during maximum jaw protrusion and laterotrusion in the IVRO group and during maximum jaw protrusion in the SSRO group.

Discussion: IVRO likely achieves greater improvement in jaw movement than SSRO. Therefore, the application of IVRO could be considered in the treatment of patients with jaw deformities featuring temporomandibular joint problems.     

下颌前突患者下颌支矢状劈开截骨术后髁突运动轨迹的改变

目的:研究双侧下颌支矢状劈开截骨术对下颌前突患者髁突运动轨迹的影响。方法:采用ARCUSdigma下颌三维运动轨迹描记仪,以髁突运动中心为参考点,研究30例正常受试者、14例下颌前突患者手术前后开口、前伸和左右侧向髁突运动的轨迹。用SPSSV11.0统计软件包进行配对t检验和成组t检验。结果:下颌前突患者术前、术后、正常组左侧髁突的运动轨迹与右侧基本相同,左侧髁突与右侧的开口、前伸和侧方运动范围无显著性差异(P>0.05)。术前组与正常组髁突运动轨迹差别较大,术前开口、前伸和侧方运动范围均小于正常组(P<0.05);术后与正常组髁突运动轨迹接近,术后开口、前伸和侧方运动范围与正常组无统计学差异;术前与术后组髁突运动轨迹差别较大,术前开口、前伸和侧方运动范围均显著小于术后组(P<0.05)。结论:下颌前突患者手术后,随着术后正畸治疗及咬合自我调整,建立了正常的咬合引导关系,使下颌功能运动趋向正常。     

Stability after sagittal split ramus osteotomy without post-operative maxillomandibular fixation in the treatment of prognathic patients with asymmetric mandibles

This study was designed to examine the post-operative stability in prognathic patients with mandibular asymmetry, who underwent sagittal split ramus osteotomy (SSRO) of the mandible and titanium screw fixation without post-operative maxillomandibular fixation (MMF). Twenty prognathic patients were examined. An appliance for repositioning the proximal segment was applied during surgery in all patients. Ten patients with symmetric mandibles underwent post-operative MMF with stainless steel wire and intermaxillary rubber traction after removal of MMF (Group I), and the other 10 patients with asymmetric mandibles received only intermaxillary rubber traction post-operatively (Group II). Posteroanterior cephalograms were obtained pre-operatively; 2–3 days post-operatively; and 3, 6, and 12 months after surgery. Changes in the positions of the gonion points (Go) and upper and lower incisors (U-1 and L-1) were examined. In both groups, the Go tended to shift laterally, as a consequence of the operation. Although the tendencies of the post-operative changes in (Go) points of Groups I and II were different, statistical analyses revealed no differences between the two groups. At the late stage of follow-up, the absolute value of the change in L-1 tended to be larger in Group II than in Group I, but without statistical significance. This study suggests that post-operative change in prognathic patients with asymmetric mandibles treated without post-operative MMF is comparable to that in patients with symmetric mandibles treated with post-operative MMF. Therefore, post-operative MMF might be avoided, even in prognathic patients with asymmetric mandibles.     

Independent risk factors for long-term skeletal relapse after mandibular advancement with bilateral sagittal split osteotomy

The purpose of this retrospective cohort study was to identify the independent risk factors for long-term skeletal relapse following mandibular advancement with bilateral sagittal split osteotomy. Univariate and multivariate linear regression analyses were performed including nine common risk factors for relapse as independent variables and horizontal/vertical long-term (≥2 years) skeletal relapse as dependent variables. Ninety-six patients were analyzed; 66 were female (68.8%) and the average age of the patients was 29.7 ± 10.5 years. Over an average follow-up of 3.8 ± 1.8 years after an initial mandibular advancement of 8.8 ± 2.4 mm, long-term skeletal relapse of 1.6 ± 1.0 mm horizontal and 0.9 ± 0.7 mm vertical was found. Multivariate analysis identified age, preoperative mandibular plane angle (MPA), bimaxillary surgery, counterclockwise mandibular rotation, and the magnitude of mandibular advancement to be significantly associated with horizontal long-term skeletal relapse. Preoperative MPA, counterclockwise mandibular rotation, and the magnitude of mandibular advancement were significantly associated with vertical long-term skeletal relapse. Thus preoperative MPA, the magnitude of mandibular advancement, and counterclockwise mandibular rotation of the mandible were found to be independent risk factors for both horizontal and vertical long-term skeletal relapse. Although long-term skeletal relapse cannot be avoided entirely, understanding the independent risk factors and their contributions will optimize treatment planning and long-term stability.     

双侧升支矢状劈开截骨后退下颌术后骨的稳定性的研究

目的：探讨双侧升支矢状劈开截骨术（BSSRO）后退下颌骨以钢丝结扎固定两骨段加颌间固定术后骨的稳定性，了解导致复发的有关因素。方法：双侧下颌升支矢状劈开截骨手术后退下颌的患者14例，于手术前1周，手术后1周，术后6个月分别拍摄定位头颅侧位片及许勒位X线片，用于测量下颌移动的距离及确定下颌骨髁状突的位置。结果：双侧下颌升支矢状劈开截骨后退术后，6个月的复发率为27.2%，多元逐步回归分析示下颌后退的距离与复发相关。结论：BSSRO后退下颌骨的距离越大，术后下颌骨向前移位的可能越大。     

下颌矢状劈开截骨术相关下颌管空间定位的三维CT研究

目的：应用三维CT影像测量下颌管解剖位置与骨皮质和磨牙的关系,为避免下颌矢状劈开截骨术中损伤下齿槽神经血管提供指导。方法：选择50名正常成人下颌骨三维CT扫描图像,应用AW4．4图像处理软件分别在第二前磨牙,第一、第二磨牙正中,下颌磨牙后区处测量下颌管的解剖位置。结果：通过获得的CT数据研究中国人下颌神经管的解剖位置与骨皮质和磨牙的联系,在第二磨牙区域下颌管距离颊侧骨皮质最远（平均7．82mm,最小4．9mm）。结论：在第二磨牙区域下颌体最厚,对于下颌矢状劈开截骨术的颊侧垂直切口须在下颌第二磨牙区域,这个区域骨质最厚并且下颌管距离颊侧骨皮质最远。对于下颌矢状劈开截骨术颊侧垂直切口的安全深度是4．9mm。     

The assessment of the short‐ and long‐term changes in the condylar position following sagittal split ramus osteotomy (SSRO) with rigid fixation

Summary The purpose of this study was to compare the short‐ and long‐term changes in condylar position related to the glenoid fossa, and skeletal and occlusal stability after orthognathic surgery. All of the study patients were assessed by cone‐beam computed tomography images for condylar rotational changes and anteroposterior position in the pre‐surgery, post‐surgery and post‐retention period. The condylar positions were evaluated on three planes: axial, coronal and sagittal. In the skeletal and occlusal measurements, there was no significant difference between the post‐surgery group and the post‐retention group. After sagittal split ramus osteotomy (SSRO), the condyle on the axial plane rotated inward (P < 0·05) and maintained during the post‐retention period. In the anteroposterior condylar position related to the glenoid fossa, the condyles had changed from the anterior position in the pre‐surgery group to a concentric position in the post‐surgery group and then returned to the anterior position in the post‐retention groups. These results suggested that the changed anteroposterior condylar position in the glenoid fossa after SSRO with rigid fixation had moved from a concentric to anterior position for post‐retention period.     

Tongue–palatal contact changes in patients with skeletal mandibular prognathism after sagittal split ramus osteotomy: an electropalatography study

The purpose of this study was to investigate the changes in tongue–palatal contact patterns using electropalatography (EPG) before and after sagittal split ramus osteotomy (SSRO) in patients with mandibular prognathism. Nine clients who underwent SSRO for mandibular setback and seven control subjects were participated in this study. Tongue–palatal contact patterns for /t/, /s/ and /k/ production were investigated using EPG before surgery and 3 months after surgery. The mean value of whole total of palate contact (WT) in the maximum contact frame was examined before and after SSRO. The correlation quantity between the change of center of gravity (COG) value and the amount of mandibular setback was also evaluated. The mean value of WT for /t/ and /s/ significantly increased after SSRO, and the EPG pattern became normal. However, a remarkable change in WT for /k/ was not observed, and the mean value was significantly larger in the SSRO group before and after surgery than in the control group. A negative correlation between COG variation and the amount of mandibular setback for /t/ and positive correlation for /s/ was observed. This study demonstrated that tongue–palatal contact patterns for /t/ and /s/ articulation improved clearly after SSRO. There was a significant correlation between COG variation and the amount of mandibular setback. However, no significant change was detected through perceptual assessment before and after SSRO. Further investigation is needed to determine whether these results will change over time.     

下颌支矢状骨劈开术并发症防治的专家共识

下颌支矢状骨劈开术（SSRO）是正颌外科中最为常用的一类矫治下颌骨畸形的手术。由于局部解剖和操作步骤的复杂性,SSRO出现各类并发症的可能性较大,甚至可能造成严重的不良后果。诊疗策略的选择及转归与并发症的类型及其临床表现密切相关。为此,国内相关专家编写本共识,对SSRO各类常见并发症的原因、预防、处置措施进行阐述,以期提高广大同行对SSRO并发症的认识,确保手术安全进行并获得良好效果。     

A long-term comparative study of two rigid internal fixation techniques in terms of masticatory function and neurosensory disturbance after mandibular correction by bilateral sagittal split ramus osteotomy

Bilateral sagittal split ramus osteotomy (BSSO) is widely used to treat mandibular prognathism. Several methods have been described for fixation of the bony segments. This study compared two methods of rigid fixation (bicortical screws and monocortical miniplates) to identify differences in postoperative masticatory function and neurosensory disturbance after 5 years of mandibular set-back correction. 77 women who had undergone BSSO for Class III malocclusion were reviewed, and masticatory functions and neurosensory recovery were examined with the appropriate indicators pre- and postoperatively (at approximately 1 month, and 1, 2, 3, 4, and 5 years). Masticatory function exhibited similar recovery patterns in both groups. Orthognathic surgery improved occlusal force and occlusal contact area, but longer than 4 years after surgery may be required for postoperative occlusal functions in prognathic patients to reach the level of healthy subjects. The groups showed no significant differences in the recovery of parameters of masticatory functions and neurosensory disturbance even 5 years after surgery. In the evaluation of temporomandibular joint function using the Helkimo index, the score was significantly higher for the screw group than for the miniplate group. This suggests that BSSO fixed with miniplates may offer a relatively safe and reliable procedure yielding adequate results and high patient satisfaction.