3D-TOF MRA对颅内动脉瘤GDC治疗随访的预期评估

目的:评价磁共振血管成像(MRA)在随访43例病人的45个颅内动脉瘤GDC栓塞后的价值.材料和方法:以数字减影血管造影(DSA)作为诊断的金标准,回顾研究43例病人的45个颅内动脉瘤(前循环34个,后循环11个)MRA检查.所有的病人在GDC栓塞治疗后9个月之内的同一周行DSA和MRA检查,这期间不作处理.分析弹簧圈内残余血流、载瘤动脉和邻近动脉血流,MRA以最大强度投影(MIP)重建和源图像为基础.结果:所有病例中,MRA能提供良好的信息.对于动脉瘤的分析,MRA的敏感性、特征性、阳性预测价值、阴性预测价值,诊断弹簧圈内残余血流分别为87.5%、100%、100%、97%,诊断瘤颈的残余血流分别为90%、100%、100%、97%.对于动脉通畅性分析,MRA的敏感性和阴性预测价值,载瘤动脉分别是90.5%和100%,邻近动脉分别是85.7%和100%.结论:在随访GDC栓塞的动脉瘤中,MRA可以作为一个筛选手段,提高检查效率,减少病人的随访风险.     

电解可脱弹簧圈栓塞治疗颅内动脉瘤

目的：分析应用电解可脱卸弹簧圈(GDC)栓塞治疗颅内动脉瘤的临床效果。方法：6例因蛛网膜下腔出血或其它神经系统症状入住我科的病人，经CT或(和)MR以及DSA检查证实为颅内动脉瘤，其中左侧后交通动脉3例，右侧后交通动脉1例，前交通动脉1例，C2段1例。瘤体直径在5．0-20．0mm之间。在神经安定 局麻下行动脉瘤栓塞术。先作载瘤动脉造影，明确动脉瘤的大小、形状、体／颈比以及与载瘤动脉的关系。再将微导管和微导丝塑型为相应的形状后经导引导管送至动脉瘤腔中部，选择合适的GDC进行填塞，直至致密填塞。结果：全部病人均一次性栓塞治疗成功，技术成功率为100％。栓塞后即刻行脑血管造影显示动脉瘤腔填塞满意，填充程度均在95％以上。全部病人均无再次出血和并发症产生。结论：GDC栓塞颅内动脉瘤是安全、有效和微创的治疗手段。     

电解可脱性弹簧圈栓塞颅内动脉瘤的体会

目的　评价电解可脱性弹簧圈栓塞 (GDC)治疗颅内动脉瘤的疗效并总结GDC的操作要点。方法　DSA检查 32例 ,发现颅内动脉瘤共 34枚 ,其中前交通动脉瘤 16枚 ,后交通动脉瘤 14枚 ,大脑中动脉动脉瘤 2枚 ,大脑后动脉 ,眼动脉各 1枚。随后用GDC进行栓塞治疗。结果　 32例 (34枚 )颅内动脉瘤栓塞成功 ,其中完全致密栓塞 (瘤颈完全封闭 ) 2 0例 ,部分栓塞 (瘤体、瘤颈可见残余 ) 12例。并发动脉瘤破裂 1例 ,治疗后痊愈。并发脑血管痉挛 2例 ,治疗后 1例遗留轻偏瘫。术后 1年内随访 6例 7枚动脉瘤 ,无明显变化。结论　GDC栓塞治疗颅内动脉瘤是一种安全可靠、有效的治疗方法 ,术者的操作技术及对并发症的正常处理是影响手术成败的重要因素 ,对部分栓塞者有必要随访观察。     

电解可脱性弹簧圈(GDC)栓塞治疗颅内动脉瘤(附11例报告)

目的探讨颅内动脉瘤应用电解可脱性弹簧圈(GDC)经血管内治疗的新方法.方法11例病人均行DSA全脑血管造影,明确动脉瘤的部位与载瘤动脉的关系,行可脱性弹簧圈治疗栓塞.结果11例中除1例动脉瘤较大用3枚电解弹簧圈闭塞外,其余均用1枚就完全闭塞动脉瘤腔,并保留了载瘤动脉的通畅.结论应用GDC经血管内闭塞颅内动脉瘤,安全、便捷、见效快.     

颅内动脉瘤栓塞术后的DCE-MRA随访

目的：评价DCE—MRA在颅内动脉瘤栓塞术后随访中的应用价值。方法：回顾分析了56例颅内动脉瘤患者血管内栓塞治疗后的DCE—MRA和DSA随访图像,以DSA为诊断标准,比较两者的随访结果,评价DCE—MRA随访的准确性。DCE—MRA的原始图像减影后行VR、MIP重建,并结合原始图像。结果：56例患者共61个动脉瘤进行了栓塞治疗,随访中发现40个动脉瘤完全栏塞,12个瘤颈残留,9个瘤体复发,动脉瘤的复发率为14．75％。DCE-MRA与DSA随访结果有良好的一致性（k=0．871,P〈0．005）,DCE—MRA随访的准确率达到93．4％,假阳性和假阴性各2例。结论：DCE—MRA是颅内动脉瘤栓塞术后的一种无创、可靠、快速的影像随访方法,有助于监测术后瘤颈残留和瘤体复发,指导临床进一步治疗。     

颅内动脉瘤破裂早期介入治疗的临床价值

目的探讨颅内动脉瘤破裂后早期行数字减影血管造影(DSA)诊断价值并介入栓塞治疗的临床价值。方法对在我院治疗的38例自发性蛛网膜下腔出血患者行头颅CT扫描及早期DSA检查,并行血管内微弹簧圈栓塞治疗及或手术夹闭,包括GDC34例,手术夹闭4例。38例患者按Hunt-Hess分级:Ⅰ级30例、Ⅱ级6例、Ⅲ级1例、Ⅳ级1例,所有病例均行DSA造影及CT扫描。结果 CT扫描均提示不同程度的自发性蛛网膜下腔出血;脑血管DSA造影诊断:前交通动脉瘤13例,后交通动脉瘤16例,大脑中动脉瘤7例,颈内动脉分叉部2例。介入栓塞及手术夹闭成功36例,占94.7%。36例随访3～35个月无再次出血,全部病例CT复查显示弹簧圈形态、位置无改变,30例6个月后复查DSA未见动脉瘤复发。2例后交通复杂动脉瘤介入栓塞失败,家属不愿手术治疗,他们分别于术后1周及1月后死亡。结论对颅内动脉瘤破裂患者需尽早行数字减影血管造影(DSA)作出早期诊断,早期进行弹簧圈血管内栓塞治疗;DSA在诊断,治疗及患者随访中均发挥非常重要的作用。     

自膨胀式支架联合可解脱弹簧圈栓塞治疗宽颈颅内动脉瘤的效果

目的探讨应用自膨胀式颅内专用支架（Neuroform支架）与可解脱微弹簧圈（GDC）栓塞相结合治疗宽颈颅内动脉瘤技术的临床应用价值。方法采用Neuroform支架与GDC结合栓塞治疗30例基底动脉宽颈动脉瘤（基底动脉末端动脉瘤16例、基底动脉千9例、基底动脉起始部5例），30例后交通宽颈动脉瘤，5例椎动脉宽颈动脉瘤。通过微导管释放Neuroform支架覆盖动脉瘤瘤颈，将另一微导管通过支架网孔进入动脉瘤腔以GDC栓塞动脉瘤。结果全部病例采用Neuroform支架结合GDC栓塞，支架均顺利通过载瘤动脉，覆盖瘤颈，其中60例致密栓塞，5例部分栓塞。2例术中发生支架内血栓。全部患者均恢复良好出院。42例术后3～6个月血管造影随访，其中39例致街栓塞的动脉瘤均未显影，载瘤动脉通畅；3例动脉瘤颈有残留。结论Neuroform颅内支架使用方便、安全，适用于颅内宽颈动脉瘤的支架辅助GDC栓塞。     

MRA在诊断颅内动脉瘤中的应用

目的：研究MRA诊断颅内动脉瘤的原理与方法，优势与不足以及临床价值。方法：选择经DSA证实为颅内动脉瘤的息者30例，行三维MRA及MRI检查，全部病例均经手术证实。结果：MRA对颅内动脉瘤的敏感性为90％，结合原始断层图像和MRI，敏感性则高达97％，较准确显示了3mm以上动脉瘤的形态、大小及与载瘤动脉的关系。对于检测血栓性动脉瘤MRA优于DSA影像。结论：MRA是一种无创伤的血管检查技术．可准确显示动脉瘤。对于Willis环区动脉瘤，MRA可取代常规血管造影。     

螺旋CT血管造影在脑动脉瘤血管内栓塞治疗中的价值

目的 探讨螺旋CT血管造影（SCTA）在指导脑动脉瘤血管内栓塞治疗中的应用价值。方法 脑动脉瘤患者48例,行SCTA明确动脉瘤的部位、形态及与载瘤动脉、邻近其他结构的关系,选择最佳显示动脉瘤与载瘤动脉关系的角度,测量动脉瘤的瘤颈、瘤体大小及动脉瘤与载瘤动脉的夹角,以指导血管内电解可脱弹簧圈（GDC）栓塞治疗。1周内行DSA造影,合适病例行GDC栓塞治疗,将SCTA与DSA结果进行对照比较。结果 （1）SCTA检出了DSA确诊的56个脑动脉瘤中的53个（94．6％）,正确诊断51个（91．1％）。（2）43个脑动脉瘤选择血管内GDC栓塞治疗,SCTA选择的血管内治疗的最佳投照角度与DSA相符41个（95．35）,SCTA测量这41个动脉瘤的瘤体与载瘤动脉夹角、瘤体及瘤颈大小并分别与DSA测量值比较,差异均无显著性意义（P值均＞0．05）。SCTA选择最佳投照角度及测量数值应以最大密度投影（MIP）图像为准,结合表面遮盖法（SSD）图像。结论 SCTA不仅对脑动脉瘤的诊断准确率高,而且对动脉瘤治疗方案的制定、术前准确及血管内栓塞治疗有很高的指导价值。     

颅内动脉瘤的比较影像学研究

目的：比较分析DSA、3D TOF MRA及CT对颅内动脉瘤的诊断价值。方法：30例颅内动脉瘤均经血管造影和手术征实，所有病例均先后作CT、3D TOF MRA及DSA检查，对其影像学特征进行比较研究。结果：DSA显示全部瘤体，呈囊状、梭形局部突出影；3D TOF MRA显示28个动脉瘤(2个假阳性)，4个未显示，其显示动脉瘤的敏感性为86．7％，假阳性为6．7％。CT显示瘤体及蛛网膜下腔出血提示动脉瘤者15例，占50％；无异常者8例，占26．7％。结论：DSA仍然是诊断颅内动脉瘤的金标准‘3D TOF MRA虽然是显示颅内动脉瘤的敏感方法之一，但对确定治疗方案价值低于DSA；CT敏感性较差，但可通过显示其间接征象提示动脉瘤。     

Prospective evaluation of time-of-flight MR angiography in the follow-up of intracranial saccular aneurysms treated with Guglielmi detachable coils

PURPOSE: The purpose of our study was to prospectively evaluate 3D time-of-flight (TOF) MR angiography (MRA) in the follow-up of 27 intracranial aneurysms treated with Guglielmi detachable coils (GDCs). METHOD: From February 1997 to June 1998, 26 patients with 27 aneurysms were included in this prospective study. Aneurysms were located in the anterior circulation in 23 cases and in the posterior circulation in 4 cases. All patients underwent 3D TOF MRA and digital subtraction angiography (DSA) in the same week within 4 months after aneurysmal treatment with GDCs. No clinical events occurred during the follow-up. We analyzed residual flow within the coil mass and within the aneurysmal neck and the patency of the parent and adjacent arteries on MRA and DSA. MRA analysis was based upon MIPPED and source images. DSA was our gold standard. RESULTS: In all cases, the quality of MRA was good enough to be informative. In aneurysmal analysis, the sensitivity, specificity, positive predictive value, and negative predictive value of MRA were, respectively, 80, 100, 100, and 96% to diagnose residual flow within the coil mass (one false-negative case) and 83, 100, 100, and 95.5% to diagnose residual flow within the aneurysmal neck (one false-negative case). In arterial analysis, sensitivity and positive predictive value of MRA were 89 and 100% to diagnose patency of the parent artery (three false-negative cases) and 83 and 100% to diagnose patency of adjacent arteries (seven false-negative cases). CONCLUSION: In the follow-up of intracranial aneurysms treated with GDCs, 3D TOF MRA could be used as a screening test to select patients that should undergo DSA and thus could improve patient follow-up in terms of risk-benefit.     

Diagnostic accuracy of 3D time-of-flight MR angiography compared with digital subtraction angiography for follow-up of coiled intracranial aneurysms: influence of aneurysm size

BACKGROUND AND PURPOSE: 3D time-of-flight MR angiography (3D TOF MRA) may be used as noninvasive alternative to digital subtraction angiography (DSA) for the follow-up of patients with intracranial aneurysms treated with Guglielmi detachable coils (GDCs). We aimed to determine the influence of aneurysm size and location on diagnostic accuracy of 3D TOF MRA for follow-up of intracranial aneurysms treated with GDCs. MATERIALS AND METHODS: Two hundred and one 3D TOF MRAs in 127 consecutive patients with 136 aneurysms were compared with DSA as standard of reference. Sensitivity and specificity of 3D TOF MRA for detection of residual or reperfusion of the aneurysms was calculated with regard to aneurysm size and location. RESULTS: Overall sensitivity and specificity of MRA was 88.5% and 92.9%, respectively. Sensitivity was lower for aneurysms 相似文献   

Follow-up of intracranial aneurysms selectively treated with coils: Prospective evaluation of contrast-enhanced MR angiography

BACKGROUND AND PURPOSE: The aim of this study was to determine the feasibility and usefulness of contrast-enhanced MR angiography (CE-MRA) for the follow-up of intracranial aneurysms treated with detachable coils, by comparing CE-MRA with digital subtraction angiography (DSA) and 3D time-of- flight (TOF) MRA. METHODS: Thirty-two patients with 42 treated aneurysms were included in the study; 6 had been treated for multiple aneurysms. All MRAs were performed with a 1.5T unit within 48 hours of DSA. We performed 2 types of acquisition: a 3D TOF sequence and CE-MRA. Twenty-eight patients were included 1 year after endovascular treatment, and 4 patients, after 3 years or more. DSA was the technique of reference for the detection of a residual neck or residual aneurysm. RESULTS: Compared with DSA, the sensitivity of MRA was good. For the detection of residual neck, there was no significant difference between the results of 3D TOF MRA (sensitivity, 75%-87.5%; specificity, 92.9%, according to both readers) and CE-MRA (sensitivity, 75%-82.1%; specificity, 85.7%-92.9%). For the detection of residual aneurysm, sensitivity and specificity of both techniques were the same, respectively 80%-100% and 97.3%-100%. Therefore, CE-MRA was not better than 3D TOF MRA for the detection of residual neck or residual aneurysm. For large treated aneurysms, there was no difference between decisions regarding further therapy after CE and 3D TOF MRA, even though CE-MRA with a short echotime and enhancement gave fewer artifacts and better visualization of recanalization than 3D TOF MRA. The interpretation of transverse source images and the detection of coil mesh packing seemed easier with 3D TOF imaging. CONCLUSION: This prospective study did not show that CE-MRA was significantly better than 3D TOF MRA for depicting aneurysm or neck remnants after selective endovascular treatment using coils. For aneurysms treated with coils, 3D TOF MRA seems a valid and useful technique for the follow-up of coiled aneurysms.     

Three-dimensional time-of-flight (3D TOF) magnetic resonance angiography (MRA) and contrast-enhanced MRA of intracranial aneurysms treated with platinum coils

Background: Contrast-enhanced magnetic resonance angiography (CE-MRA) is less prone to flow-related signal intensity loss than three-dimensional time-of-flight (3D TOF) MRA and may therefore be more sensitive for detection of residual patency in platinum coil-treated intracranial aneurysms.

Purpose: To compare MRA and CE-MRA in the follow-up of intracranial aneurysms treated with platinum coils.

Material and Methods: CE-MRA and 3D TOF MRA (pre- and postcontrast injection) of the intracranial vasculature was performed at 1.5T in 38 patients (47 aneurysms) referred for DSA in the follow-up of coiled intracranial aneurysms.

Results: DSA showed aneurysm patency in 22/47 investigations. Patent aneurysm components were observed with CE-MRA in 18/22 cases, and with 3D TOF MRA in 21/22 cases. There was no significant difference in patent aneurysm component size between CE-MRA and 3D TOF MRA. In addition, CE-MRA showed six, 3D TOF MRA before contrast injection showed seven, and 3D TOF MRA after contrast injection showed eight cases with patent aneurysm components not observed on DSA.

Conclusion: 3D TOF MRA was highly sensitive for detection of patent aneurysm components, and at least as sensitive as CE-MRA. Residual aneurysm patency seems to be better visualized with MRA than with DSA in some cases.     

Time-of-flight MR angiography targeted to coiled intracranial aneurysms is more sensitive to residual flow than is digital subtraction angiography

BACKGROUND AND PURPOSE: For intracranial aneurysms treated with Guglielmi detachable coils, long-term follow-up is mandatory because coil compaction may occur and aneurysms may recur. The purpose of this study was to establish a noninvasive technique to visualize residual flow in coiled aneurysms. METHODS: We designed a 3D time-of-flight (3D-TOF) MR angiography (MRA) technique targeted to depict coiled aneurysms that employed a very short TE (1.54-1.60 ms) and a high spatial resolution (0.3 x 0.3 x 0.3 mm3 with zero-filling) to diminish spin dephasing. To diminish spin saturation, image volume was carefully positioned so that the neck of the targeted aneurysm was within 2 cm of the inflow portion along the stream of blood. Fifty-one MRA images of 39 coiled aneurysms in 39 patients were compared with digital subtraction angiography (DSA) images. DSA and MRA findings were interpolated retrospectively for parent and branch arteries' patency, as well as residual flow in aneurysms. In the latest 11 MR studies, a dark-blood 3D turbo spin-echo sequence was added to MRA to negate the effect high-signal-intensity thrombus. RESULTS: MRA visualized all parent and branch arteries with DSA confirmation. MRA visualized residual flow more frequently (38 studies) than did DSA (25 studies). Residual flow space visualized with MRA was always similar to or larger than that with DSA. The dark-blood sequence completely suppressed intraluminal high signal intensity on MRA images and confirmed that the high signal intensity was not due to thrombus. CONCLUSION: TOF MRA targeted to depict coiled intracranial aneurysms is noninvasive and superior to DSA in visualization of residual flow and, hence, useful for follow-up of coiled aneurysms.     

MR angiography at 3T versus digital subtraction angiography in the follow-up of intracranial aneurysms treated with detachable coils

BACKGROUND AND PURPOSE: Digital subtraction angiography (DSA) is used to follow-up intracranial aneurysms treated with detachable coils to identify recurrence and determine need for additional treatment. However, DSA is invasive and involves a small risk of neurologic complications. We assessed the feasibility and usefulness of 3D time-of-flight (TOF) MR angiography (MRA) performed at 3T compared with DSA for the follow-up of coil-treated intracranial aneurysms. METHODS: In a prospective study, 20 consecutive patients with 21 intracranial aneurysms treated with coils underwent DSA and nonenhanced and enhanced multiple overlapping thin-slab acquisition 3D TOF MRA at 3T on the same day at a mean follow-up of 6 months (range, 4-14 months) after coil placement. MRA images were evaluated for presence of artifacts, presence and size of aneurysm remnants and recurrences, patency of parent and branch vessels, and added value of contrast material enhancement. MRA and DSA findings were compared. RESULTS: Interobserver agreement of MRA was good, as was agreement between MRA and DSA. All three recurrences that needed additional treatment were detected with MRA. Minor disagreement occurred in four cases: three coil-treated aneurysms were scored on MRA images as having a small remnant, whereas on DSA images these aneurysms were occluded; the other aneurysm was scored on MRA images as having a small remnant, whereas on DSA images this was a small recurrence. Use of contrast material had no additional value. Coil-related MR imaging artifacts were minimal and did not interfere with evaluation of the occlusion status of the aneurysm. CONCLUSION: High-spatial-resolution 3D TOF MRA at 3T is feasible and useful in the follow-up of patients with intracranial aneurysms treated with coil placement.     

MR angiography in the follow-up of coiled cerebral aneurysms after treatment with Guglielmi detachable coils

Purpose: Intra-arterial digital subtraction angiography (DSA) has been considered the gold standard examination in the follow-up of patients treated with Guglielmi detachable coils (GDCs). However, DSA is an invasive and expensive investigation and results in exposure to ionising radiation to both patient and operator. The aim of this study was to compare MR angiography (MRA) with DSA with regard to patency of the occlusion of aneurysms following GDC treatment.Material and Methods: We performed 75 MRA and DSA examinations on 51 patients treated with GDCs. The examinations were performed 3-36 months after embolisation and the interval between MRA and DSA was less than 1 week. Hard copies of both studies were interpreted retrospectively and independently for residual flow within the aneurysm, residual aneurysmal neck, and parent and branch vessel flow.Results: Patency status of parent and branch vessel flow was correctly identified with MRA in all patients except 1. The sensitivity of MRA in revealing residual flow within the aneurysm was 97%. The specificity in ruling out residual flow within the aneurysm was 91%.Conclusion: MRA may replace DSA in the long-term follow-up of coiled cerebral aneurysms. The initial follow-up examination should, however, include both modalities.     

Three-dimensional time-of-flight MR angiography for evaluation of intracranial aneurysms after endosaccular packing with Guglielmi detachable coils: comparison with 3D digital subtraction angiography

The sensitivities and specificities of three-dimensional time-of-flight MR angiography (3D-TOF MRA) and 3D digital subtraction angiography (3D-DSA) were compared for evaluation of cerebral aneurysms after endosaccular packing with Guglielmi detachable coils (GDCs). Thirty-three patients with 33 aneurysms were included in this prospective study. 3D-TOF MRA and 3D-DSA were performed in the same week on all patients. Maximal intensity projection (MIP) and 3D reconstructed MRA images were compared with 3D-DSA images. The diameters of residual/recurrent aneurysms detected on 3D-DSA were calculated on a workstation. In 3 (9%) of 33 aneurysms, 3D-TOF MRA did not provide reliable information due to significant susceptibility artifacts on MRA. The sensitivity and specificity rates of MRA were 72.7 and 90.9%, respectively, for the diagnosis of residual/recurrent aneurysm. The diameters of residual/recurrent aneurysms that could not be detected by MRA were significantly smaller than those of detected aneurysms (mean 1.1 vs mean 2.3 mm). In one aneurysm of the anterior communicating artery (ACoA), the relationship between the residual aneurysm and the ACoA was more evident on MRA than DSA images. MRA can detect the recurrent/residual lumen of aneurysms treated with GDCs of up to at least 1.8 mm in diameter. 3D-TOF MRA is useful for follow-up of intracranial aneurysms treated with GDCs, and could partly replace DSA.     

3D-SPACE序列结合3D-TOF MR血管成像在颅内动脉瘤支架辅助弹簧圈栓塞术后随访中的应用

目的探讨三维T1加权序列可变反转角度快速自旋回波序列(3D T1-SPACE)结合三维时间飞跃法MR血管成像(3D-TOF MRA)在颅内动脉瘤支架辅助弹簧圈栓塞术后患者随访中的应用价值。方法前瞻性收集2017年12月至2018年10月河南省人民医院收治的25例因颅内动脉瘤接受支架辅助弹簧圈栓塞术的患者,均为宽颈动脉瘤。术后6~10个月所有患者均行3D-TOF MRA、3D T1-SPACE序列MR扫描和DSA检查。分别使用3D-TOF MRA和DSA以Raymond分级法评价瘤腔栓塞情况,使用3D-TOF MRA和3D T1-SPACE序列以4分法评价载瘤动脉支架内管腔显示情况。采用配对设计的Wilcoxon秩和检验比较动脉瘤栓塞程度分级和支架内管腔显示情况。以DSA为金标准,计算3D-TOF MRA评估动脉瘤残留的特异度及准确率。结果术后6~10个月随访,对于动脉瘤闭塞情况,DSA造影显示Raymond 1级23例,2级1例,3级1例;3D-TOF MRA 1级21例,2级3例,3级1例;差异无统计学意义(Z=-0.557,P=0.577),其中有4例患者两种评估方法结果不一致。对于载瘤动脉支架内管腔情况的显示,3D-TOF MRA评分3分14例,2分8例,1分3例;3D T1-SPACE序列25例均为4分,3D T1-SPACE优于3D-TOF MRA(Z=-4.484,P<0.001)。以DSA为金标准,3D-TOF MRA结合原图像评估动脉瘤栓塞情况的特异度为86.9%(20/23),准确率为84.0%(21/25)。结论3.0 T MR 3D T1-SPACE序列可清晰显示支架内管腔,能准确判断支架内血管的通畅情况,3D-TOF MRA可充分评估动脉瘤瘤腔有无残留。将上述两种MRI血管成像技术相结合,可用于动脉瘤支架辅助栓塞术后的随访。     

三维时间飞跃法MR血管成像检出颅内动脉瘤的研究

目的分析三维时间飞跃法MR血管成像(3D TOF MRA)检出颅内动脉瘤的价值。资料与方法 36例进行了3D TOF MRA且有数字减影血管造影(DSA)和/或手术结果为对照的患者纳入本研究。以DSA和/或手术结果为参照标准,以患者为分析单位评价3D TOF MRA检出颅内动脉瘤的能力。对3D TOF MRA均检出动脉瘤者,分别测量动脉瘤的长径、短径和瘤颈,进行相关性分析。结果 36例患者中DSA和/或手术检出28例患者有28个动脉瘤,8例患者无动脉瘤;3D TOF MRA检出31例患者31个动脉瘤,5例患者无动脉瘤。以DSA和/或手术结果为参照,以患者为分析单位,3D TOF MRA检出颅内动脉瘤的敏感性、特异性和准确性分别为89.3%、75.0%、75.0%。3D TOF MRA和DSA在显示颅内动脉瘤长径、短径和瘤颈的差别无统计学意义,并且有很好的正相关性。结论 3D TOF MRA在诊断颅内动脉瘤方面具有高的敏感性和中等的特异性,高的假阳性率提示在作出小动脉瘤的诊断时需谨慎。