子宫动脉栓塞疗法治疗子宫肌瘤临床观察

目的：研究经导管动脉栓塞术治疗子宫肌瘤的临床效果。方法：选择子宫肌瘤患者21例，采用Seldinger技术行双侧子宫动脉插管，造影确认后注入PVA栓塞颗粒，阻断肌瘤血液供应。分别于术后3个月、6个月、12个月观察疗效。结果：子宫动脉栓塞术治疗后，肌瘤体积缩小，月经恢复正常，贫血、压迫症状改善。保留了子宫和卵巢完整的生理功能。结论：子官动脉栓塞术治疗子宫肌瘤是一种疗效显著的微创治疗方法。     

子宫动脉栓塞术治疗子宫肌瘤临床观察

目的：研究经导管子宫动脉栓塞术治疗子宫肌瘤的临床效果。方法：选择子宫肌瘤患者21例，采用Seldinger技术行以侧子宫动脉插管，造影确认后注入PVA栓塞颗粒，阻断肌瘤血液供应。分别于术后3个月、6个月观察疗效。结果：子宫动脉栓塞术治疗后，肌瘤体积缩小（P＜0．01），月经恢复正常，贫血、压迫症状改善。保留了子宫和卵巢完整的生理功能。结论：子宫动脉栓塞术治疗子宫肌瘤是一种疗效显著的微创治疗方法。     

经导管栓塞子宫动脉治疗子宫肌瘤（附8例报告）

目的 评价经导管栓塞子宫动脉治疗子宫肌瘤的疗效。方法8例肌壁间子宫肌瘤,经右股动脉穿刺,运用seldinger技术,将4-5F cobra导管送至双侧髂内动脉行造影,观察子宫动脉肌瘤供血染色情况。确认子宫动脉后,将导管超选至子宫动脉内,行明胶海绵颗粒栓塞,阻断肌瘤血供。结果8例肌壁问子宫肌瘤,7例双侧子宫动脉供血,1例单侧子宫动脉供血．经100％明胶海绵颗粒栓塞后造影复查,瘤体血供完全阻断,染色消失。8例术后3-4个月月经正常。术后1个月“B超”复查。证实肌瘤似较前缩小。术后3个月“B超”复查,3例肌瘤消失,术后半年“B超”复查,只有一例未完全消失,进一步证实为子宫腺肌症。术后8个月“B超”复查,腺肌症病变仍存在,但范围明显缩小,子宫大小趋于正常,临床症状完全消失。结论经导管栓塞子宫动脉是一种创伤小,治疗效果肯定的新型治疗方法。     

栓塞术治疗子宫肌瘤的临床研究

目的：评价栓塞术治疗子宫肌瘤的临床应用价值。资料与方法：73例症状性子宫肌瘤，选择性双侧子宫动脉插管造影明确子宫肌瘤血供后，分别行栓塞术。结果：本组子宫肌瘤均表现为双侧子宫动脉供血，并行一次性两侧栓塞，技术成功率100％，术后3－6个月，98．33％月经恢复正常，92．68％贫血缓解，压迫症状均缓解，肌瘤体积分别缩小47．92％和56．05％，副反应有缺血性盆腔疼痛，发热和消化道反应，余无其他严重并发症，结论：子宫动脉栓塞术治疗子宫中肌瘤安全，有效。     

子宫肌瘤动脉栓塞术的临床应用研究

目的 探索子宫肌瘤新的治疗方法，对子宫动脉栓塞治疗子宫肌瘤进行临床研究。方法 应用介入导管技术，对28例子宫肌瘤行双侧子宫动脉栓塞治疗。选用直径350μ～500μ聚乙烯醇颗粒(PVA)100～200mg。结果 随访3～18个月瘤体缩小36．8％～82．6％。所有出血病例，月经恢复正常，血红蛋白升至正常范围3例黏膜膜下肌瘤术后自然脱落。对13例多发性肌瘤同样有效。本组有效率92．8％(26／28)结论 子宫动脉栓塞术治疗子宫肌瘤，疗效显著，并发症少，患者乐于接受，可成为子宫肌瘤这一常见疾病的支柱疗法之一。     

超选择子宫动脉栓塞术治疗子宫肌瘤疗效及并发症分析

目的：研究超选择子宫动脉栓塞术（UAE）对子宫肌瘤的临床疗效。方法：我院于1999年8月－2001年6月对405例子宫肌瘤患者进行双侧子宫动脉栓塞并对其进行随访分析疗效。结果：插管的成功率为99．8％，随访3－12个月。B超示术后3个月肌瘤体积平均缩小40％－60％，6个月后子宫肌瘤体积平均缩小50％－70％，其中22个肌瘤消失。96％的患者症状消失或改善，并发症发生率1％。结论：子宫肌瘤的介入治疗是一种创伤小，恢复快，疗效肯定的方法。     

超声在子宫肌瘤的子宫动脉栓塞术疗效评价中的价值

目的:探讨超声在子宫动脉栓塞术治疗子宫肌瘤术后疗效随访中的应用价值。材料和方法:58例子宫肌瘤患者分别在栓塞术前1周、术后1个月、6个月、12个月运用超声观察子宫大小形态、肌瘤大小形态和血流动力学的改变。结果:术后1个月子宫体积平均缩小44.24%,肌瘤体积平均缩小43.74%;术后6个月子宫体积平均缩小62.72%,肌瘤体积平均缩小61.25%;术后1年子宫体积平均缩小72.17%,肌瘤体积平均缩小70.18%。其中以单发肌瘤、内膜肌瘤患者疗效明显,肌瘤的血供较术前明显减少。结论:超声在评价子宫动脉栓塞术治疗子宫肌瘤术后疗效中有重要价值。     

经阴道彩色能量多谱勒超声在子宫肌瘤栓塞中的作用

目的探讨经阴道彩色能量多谱勒超声在子宫肌瘤栓塞治疗中的作用。资料与方法通过对27例子宫肌瘤患者进行子宫动脉栓塞治疗,并应用经阴道彩色能量多谱勒超声在栓塞前、栓塞后当天、第5d、栓塞半年内每次月经干净后第3～4d内及栓塞后每年进行检查,追踪随访34～58个月。结果栓塞前月经量过多19例,术后3个月内月经量恢复正常18例。监测发现,栓塞前肌瘤部分血流信号丰富22例,一般2例,稀少但肌瘤周边有环状血流信号2例和无血流信号1例;子宫肌层血流信号均丰富。26例栓塞后超声发现肌瘤一直无血流信号,子宫肌层血流信号在术后第5d后的每次复查均丰富。栓塞术后症状无改善1例,术后第5d和1个月发现肌瘤血流信号较丰富与术前相近。栓塞前均可探测典型的子宫动脉频谱,栓塞后子宫动脉频谱消失,在栓塞后半年到2年内子宫动脉复通。随访期内出现临床症状的再发肌瘤2例,没有临床症状但超声检查发现再发肌瘤2例。子宫体积缩小率(50.89±1.63)%(t值3.921,P<0.001),子宫肌瘤体积缩小率(56.76±7.94)%(t值4.643,P<0.001),半年后肌瘤和子宫的体积维持稳定,没有变化。结论术前对子宫肌瘤进行血流信号的检测有利于术前对肌瘤栓塞疗效的判断;术后对子宫和肌瘤的短期(栓塞后1周内)动态监测有助于对肌瘤栓塞疗效的分析;术后定期对肌瘤行超声检查有利于子宫肌瘤再发的监测。     

平阳霉素碘油乳剂选择性子宫动脉栓塞治疗症状性子宫肌瘤

目的：评价平阳霉素碘油乳剂(Pinyangrnyein lipiodol emulsion，PEE)选择性子宫动脉栓塞治疗症状性子宫肌瘤的疗效和副作用。方法：采用Seldinger方法作选择性子言动脉栓塞治疗15例子宫肌瘤患者。结果：插管栓塞成功率100％，随访1-6个月。B超示术后随访1个月肌瘤体积平均缩小25％。随访6个月，5例肌瘤消失，10例肌瘤体积平均缩小68％，并均伴有月经量的明显减少。结论：PLE选择性子宫动脉栓塞为非手术治疗症状性子宫肌瘤的较好方法。     

白芨加明胶海绵栓塞治疗子宫肌瘤的疗效观察

目的：评价白芨加明胶海绵栓塞治疗子宫肌瘤临床疗效。方法：收集我院2000年5月至2003年5月用白芨加明胶海绵栓塞治疗子宫肌瘤病人50例，采用Seldinger技术，对50例子宫肌瘤患者进行选择性子宫动脉栓塞治疗。栓塞后3个月，6个月、12个月、24个月、36个月、48个月行临床与B超随访观察疗效。结果：超选择性插管及栓塞成功率为100％，栓塞后绝大多数患者临床症状消失，随访16—48个月，1例因子宫感染坏死行子宫切除，1例40个月后肌瘤又增大行子宫切除，2例闭经，15例肌瘤消失，31例肌瘤不同程度的缩小。结论：白芨加明胶海绵栓塞治疗子宫肌瘤是一种创伤小、术后并发症发生率低，可以保留子宫及其功能的治疗措施，可使子宫肌瘤患者临床症状减轻或消失、肌瘤实体进行性缩小或消失。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.