铜针与不锈钢针留置于兔耳中央静脉内的比较

目的 铜针留置术治疗海绵状血管瘤等血管性疾病,因其特有的优点,临床已开展应用。为了解铜针留置于血管内所发生的病理变化。方法 用６０只家兔的中央静脉行铜针留置,并与不锈钢针留置比较观察血管腔内所发生的病理变化及超微结构改变。结果 铜针留置后７天内为急性炎症过程及血栓形成,１４天后形成异物性肉芽肿组织,２８－６０天后瘢痕组织纤维化、血管结构消失。不锈钢针留置诱发的炎症过程轻,血栓形成迟且较小。结论 钢     

铜针与不锈钢针留置于兔耳中央静脉内的比较

目的铜针留置术治疗海绵状血管瘤等血管性疾病,因其特有的优点,临床已开展应用。为了解铜针留置于血管内所发生的病理变化。方法我们用６０只家兔的中央静脉行铜针留置,并与不锈钢针留置比较观察血管腔内所发生的病理变化及超微结构改变。结果铜针留置后７天内为急性炎症过程及血栓形成,１４天后形成异物性肉芽肿组织,２８～６０天后瘢痕组织纤维化,血管结构消失。不锈钢针留置诱发的炎症过程轻,血栓形成迟且较小。结论铜针治疗血管性疾病优于不锈钢针。     

铜针留置兔耳缘静脉血铜变化和对肝脏组织及生化指标影响的研究

目的探讨铜针留置前后血清铜浓度变化和释放的铜离子对体内肝脏组织及生化指标所产生的影响。方法将49只新西兰兔随机分成5组,A组留置铜针1d、B组留置铜针3d、C组留置铜针5d、D组留置铜针7d,每个实验组10只,E组(留针前,正常对照组)9只。分别于留针前及留针后1、3、5和7d,抽静脉血检测血清铜离子浓度、肝功能指标,同期切取部分肝脏行HE染色,对出现阳性结果的组织标本行组织化学特殊染色、透射电镜检查。结果铜针留置后,铜离子浓度随时间的延长而增加。A、B、C、D组分别为1.40±0.49、1.45±0.53、2.01±0.40、2.38±0.83μg/ml,D组与E组(1.34±0.45μg/ml)比较有统计学意义(P<0.05);肝功能ALT与AST指标变化各组间比较无统计学意义(P>0.05),但在1、5及7d表现出较强的正相关关系,相关系数分别为0.686(P<0.05)、0.712(P<0.05)和0.768(P<0.01)。组织学检查,肝脏组织可见无菌性炎性反应,并随时间延长逐渐消退,Masson三色染色及Ag染色无明显肝小叶结构改变及肝组织纤维化。结论铜针留置兔耳缘静脉后对肝脏未产生明显的毒副作用。     

铜针留置术治疗海绵状血管瘤

自１９９２年初至１９９３年１０月，应用铜针留置术治疗海绵状血管瘤３１例，经术后３个月至１．５年的随访，有效率达１００％。文中较详细介绍了刺入铜针后全身和局部的反应，血铜、Ｂ超的变化和并发症等，我们认为铜针留置术是治疗海绵状血管瘤的有效方法。     

铜针留置术治疗海绵状血管瘤

自１９９２年初至１９９３年１０月，应用铜针留置术海绵状血管瘤３１例，经术后３个月至１．５年的随访，有效率达１００％。文中较详细介绍了刺入刺入针后全身和局部的反应，血铜、Ｂ超的变化和并发症等，我们认为铜针留置术是治疗海绵状血管瘤的有效方法。     

铜针留置术治疗海绵状血管瘤

用简便易行的铜针留置术治愈８例极为棘手的海绵状血管瘤（分别位于手掌和手指，口唇，会阴和臂部及足底）。对铜针的制备，留置的方法，时间，注意事项和全身及局部反应等作了详细的描述。     

铜针留置术治疗复杂性血管瘤临床研究

为寻求更有效的方法治疗弥漫型，部位深、边界不清的复杂性血管瘤，１９９３年３月至１９９６年６月，应用铜针埋置术治疗３５例次，行治疗前后组织学观察及术后３个月～２年随访。总有效率达９４．２８％。此方法简便易行，出血少，费用低廉，是治疗难治性血管瘤行之有效的方法之一。     

铜针治疗血管瘤的实验研究

铜针栓塞术治疗血管瘤是近年成功地应用于临床的新技术。通过实验研究证实了；铜针刺入并留置血管瘤腔内，引起该部位的血管内皮肿胀、破溃、血栓形成，继而血管外成纤维细胞大量长入血栓内，血管壁破坏、消失、纤维组织替代，瘤腔纤维经，萎缩，血管瘤治愈这一显微组织学变化的过程。     

铜针治疗血管瘤的疗效分析

目的分析铜针的各种使用方法对血管瘤的治疗效果。方法分别应用单纯留置铜针、通电后留置铜针、铜针通电后切除病变等方法治疗蔓状血管瘤、海绵状血管瘤或脉管畸形105例，统计分析术后早、晚期的疗效及复发情况。结果早期总有效率为94．3％，晚期总有效率为88．6％，复发率为28．6％，通电后切除效果最好，通电可以缩短留针时间42．6％，P〈0．01，差异有统计学意义。结论应用铜针治疗海绵状血管瘤及脉管畸形疗效肯定，与通电方法相结合效果可以提高。     

铜针通电对大鼠静脉血栓形成的实验研究

目的　了解铜针通电与血管内血栓形成的关系。方法　选用大鼠为实验对象 ,分为腹壁浅静脉组、股静脉组。通电时测定电流 ,通电后观察血管内血栓形成情况和血管及其周围组织形态变化。结果　① 4V直流电形成血栓时对血管损伤最小 ;②电流随通电时间的延长逐渐下降 ,趋向 0 1mA ;③用相同直径的铜针对不同直径的血管通电后 ,血管内血栓形成时间不同。铜针直径与血管直径相近者 (P >0 0 5 ) ,血栓形成的最短时间为 5 5min ,开始出现血管及其周围组织破坏时间为 10 5min ;铜针直径明显小于血管直径者 (P <0 0 5 ) ,血栓形成的最短时间为 7 5min ,开始出现血管及其周围组织破坏时间为 17 5min。结论　铜针通电对大鼠静脉血栓形成的最佳条件 :通电电压为 4V直流电 ,血栓形成的时间段为 5 5～ 10 5min或 7 5～ 17 5min。     

铜针通电治疗血管瘤并发急性溶血

目的 探讨铜针通电治疗血管瘤并发急性血管内[溶血的原因。方法 （1）临床观察1例巨大海绵状血管瘤两次铜针通电治疗均并发严重溶血的全过程。（2）体外实验分别将铜针，铁针和不锈钢针置于健康人枸楷酸抗凝血中，接3－6V直流电30min，在通电前，中，后检测各标本血浆游离Hb值；推血片光镜下观察RBC形态，结果临床病例两次铜针通电治疗均发生严重血管内溶血，体外实验通电后RBC变形破碎，血浆游离Hb明显升高，电压越高，通电时间越长，RBC破坏越严重。结论 铜针通电治疗巨大血管瘤可能并发严重的急性血管内溶血，电流对RBC的直接损伤是导致溶血的主要因素。     

Clinical study of CHT-5302/Mp automatic copper needle therapeutic instrument on treatment of cavernous hemangioma and racemosum hemangioma

The objective of this paper is to further improve the method of treating hemangioma with the copper needle and to standardize this method. The CHT-5302/MP copper needle therapeutic instrument has been used in a number of assorted cases. A review of 180 hemangioma cases treated by this instrument verifies that it can offer sufficient electricity for clinical use. This shows that the new treatment method offers a reliable, effective means for the treatment of high- or low-flow vascular malformations and hemangiomas. As there are no complications, it is better than previous treatments for hemangioma. It can offer an effective therapy for patients who previously could not be treated or who might require excision of limbs.     

铜针疗法配合硬化剂治疗海绵状血管瘤

应用铜针疗法的基础上配合硬化剂注射治疗海绵状血管瘤。海绵状血管瘤应用铜针治疗时,拔针后从针眼里再注入硬化剂,这样,硬化剂很容易停留在已被铜针治疗过的血管瘤内,进一步破坏血管内膜,使血管瘤结成硬块最后被吸收。此法治疗３３ 例,除１ 例颈部胸骨切迹上血管瘤未治愈,余均取得满意效果。本方法疗效比单用铜针治疗或单用硬化剂治疗海绵状血管瘤效果更可靠。     

Comparison of histologic diagnosis between stereotactic core needle biopsy and open surgical biopsy

Background: This study correlates the histologic findings of stereotactic core needle biopsy (SCNB) with open surgical biopsy (OSB) and identifies which lesions can be treated definitively based only on the SCNB histology. Methods: Women who underwent SCNB between July 1, 1993, and January 1, 1969, were identified by retrospective chart review. Mammographic (MGM) lesions found by SCNB to be ductal or lobular hyperplasia with atypia, or carcinoma underwent OSB. When the histologic findings by SCNB were inconsistent with the MGM findings, the lesion also underwent OSB. Results: 799 women underwent SCNB with 96 (12%) of these going on to OSB. MGM findings in the 92 who presented without a palpable mass included microcalcifications (MCS) in 39, mass in 47, MCS and mass in 7, and tissue distortion in 3. One hundred one breast lesions biopsied first by SCNB, then by OSB were correlated histologically. Sensitivity of SCNB is 89%, with a specificity of 94%. Eight-four women (88%) were able to have definitive treatment at time of OSB because of prior SCNB, and 703/799 (88%) of women were spared OSB entirely. Conclusion: SCNB accurately identifies benign breast histology and invasive cancers in women with MGM abnormalities, a distinct advantage over fine needle aspiration cytology. SCNB does not reliably identify women with DCIS and invasion. All women with SCNB diagnosis of ductal or lobular atypia should also undergo OSB.     

Comparison between direct trocar and Veress needle insertion in laparoscopic cholecystectomy

Although the Veress needle (VN) is widely used for insufflation of the peritoneum, direct trocar (DT) insertion is going to be more popular. A lot of complications have been reported because of the use of VN. We designed a prospective, nonrandomized study for the comparison of VN and DT insertion techniques. A pneumoperitoneum was created using the VN in 135 patients and using DT insertion technique in 148 patients during a 3-year period. Although no major complication was seen in the DT group, three major complications were seen in the VN group, but there was no statistically significant difference between both groups. More frequent minor complications were seen in the VN group, but it was statistically insignificant. Surgical skill and experience of the surgeon with the entry technique who is using it is an important factor for the selection of the abdominal insufflation technique.