赴南苏丹维和二级医院门诊患者就诊情况分析

<正>中国赴南苏丹维和二级医院担负联合国驻瓦乌地区的各出兵国和联合国雇员、文职人员及其下属机构4000余人的医疗保障任务,涉及60多个国家,人员构成复杂。由于任务区疾病的种类及发病特点与国内相比,存在较大差别,这主要与任务区的地理环境、气候特征、兵员组成、部队人员的体质情况有关。门诊是维和二级医院的窗口,门诊工作的开     

女性生殖内分泌疾病与甾体激素治疗

女性生殖内分泌功能受神经内分泌系统的支配和调控,因此各种女性生殖内分泌疾病除因生殖内分泌系统本身异常或缺陷外还和神经内分泌有关.甾体激素为女性生殖内分泌疾病治疗中的主要药物.本综述对女性生殖内分泌疾病治疗中常用的甾体激素及其作用机制与用药方案作简单介绍.     

维和医疗队出征前的药品准备经验探讨

我国向南苏丹瓦乌市派遣医疗队已经11批,每批医疗队按照我国及联合国的相关要求,均顺利、圆满完成任务。由于南苏丹历经长期战乱,建国不到3年,基础设施落后,物资匮乏,维和医疗队所需物资大多需要从国内带到任务区,尤其是药品的携带,直接关系到医疗工作能否顺利展开。作者根据维和任务区对二级医院的要求及维和医疗工作的经验,特别是经历2013年南苏丹内乱后,就医疗队携带的药品     

维和医疗队出征前物资准备主要做法及体会

<正>近年来,我国先后向苏丹及南苏丹派遣维和医疗队十余批,均圆满完成任务。但由于维和驻地国情况及承担任务各异,在物资准备方面尚有许多值得注意的问题。笔者根据在维和任务区的工作经验,再结合南苏丹的实际情况,就医疗队轮换时携     

不育男性血清与精浆生殖激素间的变化关系

本文测定不育男性血清与精浆５种生殖激素。结果显示生殖激素在血清与精浆中含量变化不一致，精浆ＩＣＳＨ、ＰＲＬ分别与精子活力、密度呈正相关，血清ＩＣＳＨ、ＦＳＨ分别与精子活力、密度及血清Ｔ呈负相关。     

做好赴南苏丹维和医疗队疗养团服务保障工作的体会

<正>2012-02-17～2012-02-29笔者所在疗养院接收了赴南苏丹维和医疗队疗养团疗养任务。现将组织疗养工作的体会报告如下。1领导重视,健全组织,精心策划落实安全措施1.1成立了疗养工作领导小组及疗养工作办公室接到上级关于组织赴南苏丹维和医疗队英雄们集体疗养的指示后,     

赴南苏丹维和二级医院实施护理质量评价的效果分析

目的探讨赴南苏丹维和二级医院护理质量评价效果。方法确定赴南苏丹维和二级医院护理质量评价指标,按照指标内容实施护理质量评价,对照分析实施护理质量评价前后的质量控制效果。结果实施护理质量评价后,维和二级医院护理质量明显提升,伤病员对护理工作满意率总分从92.97提高至96.84,二者比较差异具有统计学意义(P<0.05)。结论通过护理质量评价的系统实践,明确了赴南苏丹维和二级医院护理质量评价标准,优化了护理质量,提升了伤病员满意度,对增强维和医疗保障实力有积极作用。     

晕动病发病时内分泌激素变化的研究进展

晕动病是一种由于运动刺激引发的综合征。晕动症的病因至今没有完全解释清楚,但研究发现,晕动症发病时内分泌激素,如促肾上腺皮质激素、皮质醇、精氨酸加压素、血管活性肠肽以及雌激素等被释放到循环系统,关于这些内分泌激素与晕动病的关系尚不明确。本文对晕动病发病时内分泌激素的变化作一综述。     

中国维和二级医院“医院管理系统”建设构想

<正>中国驻南苏丹维和二级医院驻扎在南苏丹瓦乌,担负联合国赋予的多重医疗保障任务。医院设门诊部、住院部、药房、放射、检验等多个部门,是一所综合性医院。医疗人员定期轮换执行医疗保障任务。1现状分析目前,医院的就诊流程是患者首先到门诊做就诊登记,然后根据病情分配到各诊室。诊室医师接诊后,根据病情开具检查单、检验单、处方等,需要住院的由门诊护士办理住院手续,送患者至住院部,由住院护士办理相关手续后,医师根     

我区驻南苏丹维和二级医院在难民潮期间实施人道主义救援的做法

<正>2012年11月,济南军区抽组第十批维和医疗队赴南苏丹瓦乌执行联合国维和任务,组建二级医院。2012年12月,任务区驻地瓦乌市突发部族武装冲突,致大量人员伤亡,短时间内5000余名难民涌入UN城避难。临时难民安置点紧邻二级医院,卫生条件差,防疫形势严峻,难民中出现大批伤病员。二级医院迅速启动应急预案,积极开展国际人道主义援助,开设临时难民医疗救助点,对难民聚集区进行防疫消     

小剂量米非司酮对生殖内分泌的影响

目的探讨小剂量米非司酮对生殖内分泌的影响。方法随机抽取门诊就诊的子宫肌瘤或子宫腺肌病患者40例。均于月经的第5天开始服用米非司酮6.25mg/d,连续服用4个月,于用药前及停药1周内测量卵巢的面积以估计卵巢的大小,空腹测量血清雌二醇、FSH(卵泡刺激素)的水平,应用SPSS11.5统计软件进行数据处理。结果米非司酮治疗后,右卵巢面积小于治疗前,两者比较,差异有显著性(P<0.01)。米非司酮治疗前血雌二醇为卵泡期水平,治疗后为绝经期水平,两者比较,差异有显著性(P<0.01)。米非司酮治疗前后FSH差异无显著性(P>0.05)。结论小剂量米非司酮对垂体没有明显抑制作用,但具有雌激素样的负反馈作用;小剂量米非司酮通过抗雌激素样作用直接作用于卵巢,导致卵泡发育停止,从而使卵巢激素缺乏周期性变化而出现闭经,并伴随出现卵巢缩小及更年期症状。     

海洛因依赖者内分泌和生殖系统超微病理变化研究

目的 :探讨海洛因依赖者内分泌系统、生殖系统超微病理损害。方法 :应用透射电镜对 4例海洛因依赖者内分泌系统、生殖系统进行观察 ,并与对照组进行比较。结果 :海洛因依赖者垂体腺细胞线粒体肿胀 ,嵴断裂 ,内质网扩张 ,神经内分泌细胞及神经内分泌颗粒减少 ;甲状腺滤泡上皮细胞胞浆内细胞器减少 ;肾上腺皮质线粒体肿胀 ,可见多量溶酶体、脂滴、滑面内质网和脂褐素 ,可见髓鞘样结构 ;胰岛细胞神经内分泌颗粒丰富 ,可见脂质体退化 ,部分细胞内分泌颗粒稀少 ;睾丸和卵巢可见生殖细胞和间质细胞数量减少 ,胞内细胞器减少。对照组除偶见线粒体肿胀外 ,组织结构未见其它异常。结论 :海洛因依赖者内分泌系统和生殖系统超微病理改变呈急、慢性缺氧性变性、坏死和退行性改变     

腹腔镜下卵巢良性肿瘤剥除对生殖内分泌功能的影响

目的探讨腹腔镜下卵巢良性肿瘤剥除对生殖内分泌功能影响。方法对本院行腹腔镜下卵巢良性肿瘤剥除术的110例患者术后月经周期、激素水平记录分析。结果 110例患者单侧组术后3个月月经周期、激素水平恢复至正常水平,双侧组术后6个月月经周期、激素水平恢复至正常水平。结论腹腔镜下卵巢良性肿瘤剥除安全、可靠,同时对保留生殖内分泌功能有良好的作用,值得临床应用。     

腹腔镜下采用卵巢良性肿瘤剥除对生殖内分泌功能的影响研究

目的：探讨腹腔镜下卵巢良性肿瘤剥除对生殖内分泌功能的影响。方法选取2011年9月～2013年3月来我院就诊的卵巢良性肿瘤患者127例,根据治疗方法分为观察组（79例）及对照组（48例）。对照组采用常规经腹手术,观察组采用腹腔镜进行手术。观察两组患者治疗前后LH、E2、FSH各指标及手术时间、术中出血量、术后下床活动时间及术后住院时间等指标。结果观察组患者治疗前后比较,LH、E2、FSH各指标差异均显著（t=35.136,9.354,12.312,P＜0.05）。对照组患者治疗前后比较,LH、E2、FSH各指标差异均显著（t=28.651,16.357,4.137,P＜0.05）。观察组治疗后LH、E2、FSH各指标与对照组比较,差异有统计学意义（t=29.316,13.168,9.662,P＜0.05）。观察组手术时间、术中出血量、术后下床活动时间及术后住院时间均优于对照组（t分别为7.356,21.245,6.346,9.116,P＜0.05）。观察组的AMH指数,基础窦卵泡数（AFC）及bFSH等指标皆显著高于对照组,差异显著（t分别为6.337,7.365,5.134,P＜0.05）。结论卵巢良性肿瘤剥除具有较好的安全性及可靠性,可以较好的保留患者的生殖内分泌功能。     

Hydrogen sulfide in the endocrine and reproductive systems

Hydrogen sulfide (H(2)S) is now considered a member of a group of signaling molecules termed 'gasotransmitters'. H(2)S has been shown to be generated in the endocrine and reproductive organs and elicits various actions. H(2)S modulates insulin secretion in pancreatic islets. Adipose tissues have the ability to produce H(2)S, which regulates the local insulin sensitivity and vascular responsiveness. H(2)S also acts on the hypothalamic-pituitary-adrenal axis and is involved in stress responses. The effects of H(2)S on male and female reproductive function have also attracted great interest for their potential therapeutic implications in reproductive disorders. Alterations of H(2)S biosynthesis are associated with various endocrine disorders, and hormones can be important factors in the regulation of H(2)S production. Understanding the regulatory mechanisms for H(2)S synthesis pathways may help develop new therapeutic strategies.     

2,3,6,7-二苯并蒽对大鼠生殖内分泌影响的研究

目的：探讨2，3，6，7－二苯并蒽对切除卵巢大鼠生殖内分泌和子宫雌激素受体的影响。方法：应用放射免疫法（RIA）和放射配体受体法。结果：2，3，6，7－二苯并蒽在皮下注射5d后，低及高剂量均可导致切除卵巢的大鼠子宫湿重明显增加（P＜0．01），低及高剂量组大鼠子宫雌激素受体数量与对照组比，差异无显著性（P＞0．05），但高剂量组大鼠子宫雌激素受体亲和力明显高于对照组（P＜0．05）。低及高剂量组血清中卵泡刺激素（FSH）含量与对照组比，差异无显著性（P＞0．05），低及,高剂量组血清中黄体生成素（LH）含量明显降低（P＜0．01，P＜0．05），高剂量组血清中催乳素（PRL）含量明显增加（P＜0．05）。结论：2，3，6，7－二苯并蒽雌激素活性的作用机制可能是干扰下丘脑－垂体－卵巢轴对生殖内分泌的调控。     

Effects of endocrine disruptors on developmental and reproductive functions

Endocrine disruptors (EDs) are exogenous environmental molecules that may affect the synthesis, secretion, transport, metabolism, binding, action, and catabolism of natural hormones in the body. EDs may thus interact with the endocrine system of animals and humans and can exert this effect even when present in minute amounts. EDs have adverse impacts on a number of developmental functions in wildlife and humans. Critical periods of urogenital tract and nervous system development in-utero and during early post-natal life are especially sensitive to hormonal disruption. Furthermore a wide range of hormone-dependent organs (pituitary gland, hypothalamus, reproductive tract) are targets of EDs disrupting effects in adult subjects, possibly resulting in cell transformation and cancer. At present about 60 chemicals have been identified and characterized as EDs and belong to three main groups: (a) synthetic compounds utilized in industry, agriculture and consumer products; (b) synthetic molecules used as pharmaceutical drugs and (c) natural chemicals found in human and animal food (phytoestrogens). In the present review we will give special attention to the family of Polychlorinated biphenyls (also indicated as PCBs) because of their persistence in the environment, ability to concentrate up the food chain, continued detection in environmental matrices, and ability to be stored in the adipose tissue of animals as well as humans. The detrimental effects of these compounds, and of EDs more in general, on health and reproduction will be discussed, presenting experimental data aimed at understanding the molecular mechanisms involved in their action.     

Prevalence of blood groups in tribals of South Sudan

Prevalence of ABO blood groups and Rhesus-factor in Southern Sudanese is shown in the Study. 42.81% were group A. group AB was the least common. Only 0.47% were negative for RH-factor.     

Application of reproductive hormone peptides for tumor targeting

Targeted therapy may be a promising approach against cancer because its focus of attention is to enhance the efficacy and to reduce the side effects of antitumor agents through high selectivity. One of targeted strategies is to use tumor-specific ligands as targeting moieties to carry drugs into tumor cells, and use the receptors that expressed on tumor cells as target sites to bind with peptide ligands. The fact that the distributions of reproductive hormone receptors are relatively limited in normal tissues makes it possible to use them as targeted sites and use hormone peptides as targeting moieties for cancer treatment. Until now many tumor targeting approaches with reproductive hormone peptides have been developed, and some of them have been introduced into clinical trials. Here a review is given to discuss the targeted antitumor therapeutic strategies based on gonadotropin-releasing hormone, follicle-stimulating hormones, luteinizing hormone, human chorionic gonadotropin and their receptors.