Trombosis de la arteria cerebral media en un neonato afectado de déficit de proteína C

Stroke is an important cause of mortality and chronic neurological morbidity in children. Perinatal stroke has been defined as a cerebrovascular event occurring between 28 weeks of fetal life and the 28^th postnatal day. The most common manifestation of stroke is neonatal seizures but this entity may also be asymptomatic until months after birth when asymmetry of reach and grasp, failure to reach developmental milestones, or postnatal seizures can develop. Improvements in neuroimaging and its availability have increased the diagnosis and awareness of perinatal stroke in newborns and infants with neurological symptoms. Obstetricians are responsible for monitoring pregnancies at high thromboembolic risk, but rarely consider the effect this has on the fetus or newborn. We present the case of a newborn with perinatal stroke associated with protein-C deficiency.