肝腺瘤的综合影像诊断

目的：描述肝腺瘤的超声（US），CT和MRI表现与病理基础，探讨综合影像对肝腺瘤的诊断价值。方法：回顾性分析经手术切除，病理症实的6例肝腺瘤的US，CT和MRI表现，并与病理所见对照。结果：6例肝腺瘤均为单发肿块，1例术前综合影像诊断为肝腺瘤，4例误诊为肝癌，例误诊为肝局灶结节性增生。US：6例呈稍低或低回声，4例有低回声晕，彩色多普勒显示6例肿块内有较丰富的门脉样血流和低速动脉样血流，CT：6例为稍低或低密度，4例有假包膜，4例动脉期，门脉期均轻度强化，1例动脉期中度强化，门脉期轻度强化，MRI：T1WI和T2WI上，6例表现为以高信号为主的混杂信号，用脂肪抑制后T1WI上的高信号无变化；2例动脉期显著强化，门脉期和延迟期轻度强化，3例动脉期，门脉期和延迟基匀轻度强化。6例均有假包膜，且在门脉期或延迟期现轻度强化。结论：肝腺瘤的综合影像表现缺乏特性性。对有假包膜和混杂高信号（用脂肪抑制后T1WI上的高信号无变化）的多血供肿块应考虑到肝腺瘤的诊断。     

肝脏局灶结节性增生的CT、MRI诊断

目的:评估CT、MRI对肝脏局灶结节性增生(focal nodular hyperplasia,FNH)的诊断价值.材料和方法:回顾性分析9例FNH(6例经病理证实,3例经磁共振特异性对比剂Resovist证实)的CT、MRI表现和术前或穿刺前诊断.结果:8例为单发病灶、1例为3个病灶.10个病灶呈稍低密度,其中7个T1WI为稍低信号、T2WI稍高信号,3个病灶T1WI和T2WI为稍高信号;1个病灶为等密度和等信号;CT动脉期明显增强、门静脉期轻度增强或无增强;MRI的增强方式与CT相似,但10个病灶存在明显的延迟增强.7个病灶检出瘢痕,T1WI呈低信号、T2WI高信号,动脉期和门静脉期无增强、延迟期轻至中度增强.8例单发病灶均正确诊断为FNH.结论:CT和MRI能显示FNH的特征性改变并提高诊断的准确性.     

肝脏局灶性结节增生的螺旋CT和MRI诊断

目的 :分析肝脏局灶性结节增生 (FNH)平扫和动态增强的螺旋CT、MRI表现 ,提高FNH诊断符合率。方法 :对 13例经手术病理证实的FNH影像学表现进行回顾性分析。螺旋CT检查 8例 ,MRI检查 6例 ,其中 1例同时做CT和MRI检查。结果 :8例CT平扫病灶均呈低密度 ,均匀或不均匀。增强动脉期扫描除中心疤痕外 ,所有病灶均有明显均匀强化 ,其中 4例还可见到病灶中心或周边增粗、扭曲的动脉。门脉期和延迟期扫描 4例呈略高密度、4例病灶呈等密度或略低密度 ,4例伴有中心疤痕者均有延迟强化。MRI检查 6例 ,病灶均呈不均匀略长或等T1及T2 信号 ,增强动脉期呈明显强化 ,门脉期及延迟期呈等或略高强化 ,4例MRI平扫显示中央瘢痕者有延迟强化。结论 :平扫和动态增强螺旋CT、MRI能较全面显示FNH的病理特征和血供特点 ,明显地提高与其它富血管恶性肿瘤的鉴别诊断能力     

肝局灶性结节增生的多种影像学表现分析

目的分析肝局灶性结节增生(FNH)的CT、DSA及18FDG正电子发射体层摄影术(PET)的影像表现,认识FNH的多种影像学特征.资料与方法 10例FNH经手术病理证实,回顾分析其多种影像学表现.10例均行CT平扫及动态增强扫描,其中4例行DSA肝动脉造影,2例行18FDG PET显像.结果 10例FNH均为单发性结节,位于肝右叶8例,肝左叶2例.肿瘤直径1.1～9.3 cm,平均5.1 cm.CT检查10例,平扫均为低密度,其中8例病灶(直径均＞3.0 cm)中央区有星芒状的更低密度区;增强扫描,动脉期9个结节明显强化,1个中等强化,病灶中央更低密度区无强化,2个病灶中央或周边见增粗迂曲血管,其中1个尚可见动脉-门脉、动脉-静脉分流现象;门脉期病灶密度稍有下降,8个高于或等于肝实质,2个低于肝实质;延迟期7个等于或略高于肝实质,3个低于肝实质,5个病灶中央更低密度有强化.血管造影:4例FNH的供血动脉均来自肝动脉系统,供血动脉增粗、扭曲, 1例血管分支放射状分布,周围呈环绕状聚集染色,中央局限性缺损,另3个分支血管紊乱并呈抱球征,1个尚见动脉-门脉、动脉-静脉分流.2例18FDG PET显像均未见异常放射性浓聚.结论 FNH CT平扫为低密度,增强扫描以"快进慢出"为主要特征,而血管造影显示肝动脉供血为主,表现为供血动脉增粗、扭曲,呈轮辐状向周围发散.这些影像特征有利于FNH的定性诊断.     

Differentiation of focal nodular hyperplasia and hepatocellular adenoma by contrast-enhanced ultrasound

Non-invasive differentiation of focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) is difficult. The aim of this study was to assess the accuracy of contrast-enhanced phase inversion ultrasound to differentiate between histologically proven FNH and HCA, analysing the arterial and (early) portal venous phase. 32 patients with histological proven FNH (n=24) or HCA (n=8) have been included in this prospective study. Examination technique: Siemens Elegra, phase inversion harmonic imaging (PIHI) with low mechanical index (MI)<0.2-0.3 using SonoVue (BR 1). The contrast enhancing tumour characteristics were evaluated during the hepatic arterial (starting 8-22 s) and early portal venous phase (starting 12-30 s). The image analysis was performed by three examiners. In 23 of 24 patients with FNH the contrast pattern revealed pronounced arterial and (early) portal venous enhancement. Homogeneous enhancement was detected during the hepatic arterial phase in all eight patients with HCA. In contrast to patients with FNH, no enhancement was seen during the portal venous phase. In conclusion, contrast-enhanced phase inversion ultrasound demonstrated pronounced arterial and portal venous enhancement in patients with focal nodular hyperplasia. In contrast, after homogeneous enhancement during hepatic arterial phase, no enhancement during hepatic portal venous phase was detected in patients with hepatocellular adenoma. Therefore, this technique might improve the functional characterization of benign hypervascular focal liver lesions.     

肝脏局灶性结节增生的MRI征象分析

目的:探讨肝局灶性结节增生(FNH)的典型及不典型MRI表现及与病理特点的相关性,提高FNH诊断的准确性。方法:回顾性分析33例(共40个病灶)经手术病理证实的FNH的MRI平扫和增强表现。结果:28例为单发,5例为多发病灶。40个病灶在T1WI呈等或稍低信号,在T2WI呈等或稍低信号,增强扫描动脉期31个病灶(94%)明显强化,门脉期及延迟期呈稍高或等信号;1例动脉期未见明显强化,门脉期及延迟期可见强化;1例动脉期边缘明显强化,门脉期及延迟期逐渐强化。12个病灶(30%)中心可见纤维瘢痕,11个延迟期强化,1个未见明显强化。3个病灶(8%)边缘见假包膜,延迟期可见强化。结论:MRI能较好地反映FNH内部组织学情况及血供特点,充分认识FNH的典型征象及不典型表现能帮助我们准备地做出诊断,从而避免不必要的活检及手术。     

Hepatocellular carcinoma in cirrhosis: enhancement patterns at dynamic gadolinium- and superparamagnetic iron oxide-enhanced T1-weighted MR imaging

PURPOSE: To prospectively compare intraindividual differences in enhancement patterns between gadolinium- and superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance (MR) imaging in patients with histologically proved hepatocellular carcinoma (HCC). MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained. Twenty-two patients (18 men, four women; mean age, 58.9 years) with 36 pathologically proved HCC lesions underwent contrast material-enhanced dynamic T1-weighted gradient-echo MR imaging twice. Gadopentetate dimeglumine was used at the first session. After a mean interval of 5 days, a second session was performed with a bolus-injectable SPIO agent, ferucarbotran. Qualitative analysis of contrast enhancement patterns with each agent during hepatic arterial, portal venous, and equilibrium phases was performed by two readers who classified lesions as isointense, hypointense, or hyperintense compared with surrounding liver parenchyma and searched for presence of hyperintense peritumoral ring enhancement. Results of signal intensity analysis during different vascular phases at both sessions were compared by using the McNemar test, and kappa statistic was used to evaluate agreement between signal intensity and enhancement pattern of lesions during different vascular phases. RESULTS: On gadolinium-enhanced hepatic arterial phase images, HCC lesions (n = 36) were hyperintense in 21 (58%) cases, hypointense in 10 (28%), and isointense in five (14%). On ferucarbotran-enhanced hepatic arterial phase images, HCC lesions were isointense in 18 (50%) cases, hypointense in 11 (31%), and hyperintense in seven (19%). On gadolinium-enhanced portal venous and equilibrium phase images, respectively, HCC lesions were hypointense in 17 (47%) and 21 (58%) cases, hyperintense in 10 (28%) cases and one (3%) case, and isointense in nine (25%) and 14 (39%) cases. On ferucarbotran-enhanced portal venous and equilibrium phase images, respectively, HCC lesions were hypointense in 15 (42%) and 11 (31%) cases, hyperintense in three (8%) and three (8%) cases, and isointense in 18 (50%) and 22 (61%) cases. CONCLUSION: For HCC, contrast enhancement pattern on T1-weighted gradient-echo MR images shows marked variability with gadolinium or SPIO contrast agents.     

螺旋CT双期扫描诊断肝细胞癌的价值

目的 探讨螺旋CT双期扫描对肝细胞癌的诊断价值一方法采用西门子Somatom Balanrr高速螺旋CT扫描机，对37例肝细胞癌患者进行螺旋CT双期扫描，高压注射器注射造影剂。全盱平扫后，分别于开始注射造影剂后25s．60s行伞肝螺旋CT动脉、门静脉双期扫描、将螺旋CT扫描结果与普通CT扫描进行对照一其中男26例，女11例。年龄37岁～75岁，平均57．8岁。结果 37例中，动脉期肿瘤明显强化31例、轻度强化6例，动-静脉瘘5例。门静脉期，肿瘤全部呈低密度门静脉瘤栓11例。结论 HCC螺旋CT动脉、门静脉双期增强扫描，病灶强化特征可反映其组织病理学改变的特点，诊断准确性高     

肝局灶结节样增生MR、CT表现(附6例报告)

目的分析肝FNH的MR、CT表现,旨在提高对FNH认识。方法对6例肝FNH进行MR平扫及Gd-DTPA动态增强检查,其中3例CT平扫及动态增强,1例行CT平扫。结合文献分析其不典型表现。结果6例肝FNH不典型表现包括1例平扫呈明显长T1、长T2信号,动脉期弥漫不均匀强化,假包膜的存在及延迟强化;2例动脉期仅轻度强化;2例MR、CT动态增强各期表现不完全符合。结论MR、CT尤其是动态增强是诊断肝FNH的有效方法。对肝FNH的不典型表现需有足够的认识,以免误诊误治。     

肝脏局灶性结节增生的CT和MRI表现与病理对照分析

目的:探讨肝脏局灶性结节增生(FNH)的CT和MRI表现及病理基础。方法:回顾性分析18例20个经手术或穿刺活检病理证实FNH的CT和MRI表现特点,并与病理对照(CT检查12例,MRI检查10例,4例同时行CT和MRI检查)。结果:病灶大小1.8～13.5cm;CT检出11个病灶,CT平扫病灶均呈低密度,均匀或不均匀;增强扫描动脉期示除中心疤痕灶外,所有病灶均明显增强,6个病灶周边见增粗、扭曲的动脉;门脉期示病灶呈稍高密度,延时期示6个病灶呈稍高或等密度,5个病灶呈稍低密度;5个病灶的中央疤痕均延时增强。MRI检出12个病灶,病灶均呈稍长或等T1及T2信号;增强动脉期示病灶明显增强,门脉期及延时期呈稍高或等信号,7个病灶的中央疤痕延时增强。结论:CT和MRI能够显示FNH的血供特点及病理特征,动态增强扫描是诊断FNH最有效的影像学手段,在诊断和鉴别诊断中具有很大价值。     

Focal liver masses: enhancement patterns on contrast-enhanced images--concordance of US scans with CT scans and MR images

PURPOSE: To assess prospectively the concordance of enhancement patterns of focal liver masses on contrast material-enhanced ultrasonographic (US) scans with patterns on contrast-enhanced computed tomographic (CT) scans or magnetic resonance (MR) images. MATERIALS AND METHODS: This study was approved by the institutional review board; patients gave informed consent. Contrast-enhanced US and contrast-enhanced CT or MR imaging were performed in 135 patients (62 men, 73 women; mean age, 51 years) with 144 confirmed liver masses. Masses included 49 hepatocellular carcinomas, 13 metastases, 30 hemangiomas, 41 lesions of focal nodular hyperplasia, and 11 others. Randomized image sets from each modality were shown independently to three blinded readers, who answered identical questions about enhancement of the lesion and liver in the arterial and portal venous phases and changes with time. Concordance for modalities was calculated from answers of readers and consensus answers between readers, with 95% confidence intervals (CIs). The kappa values were calculated for interreader agreement. RESULTS: Features of arterial phase enhancement showed concordance of more than 76% for modalities. The highest concordance of 92% (132 of 144), with 95% CI of 86% and 95% (kappa>0.84), was for the presence of peripheral pools and centripetal progression. Concordance in the portal venous phase was lower, with agreement for predominant enhancement of the lesion in 61% (86 of 142), with 95% CI of 52% and 68% (kappa>0.83). Portal venous phase washout occurred in 75% (106 of 142), with 95% CI of 67% and 81% (kappa>0.81). The majority of discordances were for malignancies for which only US depicted no sustained enhancement in the portal venous phase. CONCLUSION: US shows high concordance with CT or MR imaging, especially for the arterial phase. Discordance in the portal venous phase may reflect the tendency of CT and MR contrast agents, unlike microbubbles, to diffuse into interstitium.     

肝脏局灶性结节增生的CT和MRI表现与病理对照研究

目的:探讨肝脏局灶性结节增生(focalnodularhyperplasia,FNH)的CT和MRI表现及病理基础。材料和方法:回顾性分析16例18个病理证实的FNHCT和MRI表现特点并与病理对照(CT检查8例,MRI检查10例,2例同时做CT和MRI检查)。结果:病灶大小2.0～14.5cm;CT检出9个病灶,CT平扫病灶均呈低密度,均匀或不均匀;增强扫描动脉期示除中心疤痕灶外,所有病灶均明显增强,4个病灶周边见增粗、扭曲的动脉;门脉期示病灶呈稍高密度,延时期示5个病灶呈稍高或等密度,4个病灶呈稍低密度;4个病灶的中央疤痕均延时增强。MRI检出11个病灶,病灶均呈稍长或等T1及T2信号;增强动脉期示病灶明显增强,门脉期及延时期呈稍高或等信号,5个病灶的中央疤痕延时增强。结论:CT和MRI能够显示FNH的病理特征及血供特点,提高对FNH的诊断率。     

Dynamic and delayed contrast enhancement in upper abdominal MRI studies: comparison of gadoxetic acid and gadobutrol

OBJECTIVE: To prospectively compare contrast properties of extracelullar (gadobutrol) and hepatospecific (gadoxetic acid) contrast agents in upper abdominal MRI studies. MATERIALS AND METHODS: Standardized (0.1 ml/kg) dose of gadobutrol (56 subjects) and gadoxetic acid (51 subjects) was administered intravenously by MRI-compatible injector at 2 ml/s, followed by 20 ml saline flush. MR signal intensity changes (SIC) between precontrast scans and arterial phase, portal venous phase, equilibrium, and delayed scans at 10 and 20 min were measured in abdominal aorta, portal vein, common bile duct, liver, and spleen. Mean SIC values for gadobutrol and gadoxetic acid were compared by a two-sample t-test with p-value <0.05 considered significant. RESULTS: In abdominal aorta, the mean SIC in the arterial phase did not significantly differ between gadobutrol (330%) and gadoxetic acid (295%). In portal vein, the mean SIC in the portal venous phase significantly differed between gadobutrol (267%) and gadoxetic acid (176%). Liver parenchyma enhancement was significantly higher for gadobutrol than for gadoxetic acid in both arterial phase (28 versus 13%) and portal venous phase (81 versus 46%). On the contrary, gadobutrol reached significantly lower mean SIC in the liver on delayed scans at 10 min (47 versus 59%) and 20 min (40 versus 67%), as well as in common bile duct at 10 min (54 versus 133%) and 20 min (57 versus 457%), respectively. In the spleen, mean SIC for gadobutrol was significantly higher at all phases. CONCLUSION: Gadobutrol showed superior enhancement of upper abdominal structures in the dynamic phases whereas gadoxetic acid showed better enhancement of the hepatobiliary structures on delayed scans.     

肝脏局灶性结节增生的CT多期增强研究

目的探讨CT多期增强扫描对肝脏局灶性结节增生的诊断价值。方法采用螺旋CT对12例肝脏局灶性结节增生进行CT平扫及多期增强扫描,增强扫描动脉期25~30 s,静脉期55~60 s,180 s后延迟扫描。结果CT平扫10例呈低密度或稍低密度,其中5例病灶中心可见不规则更低密度影,2例呈等密度。增强扫描动脉期9例明显强化,其中4例强化均匀,5例强化不均匀,其内平扫不规则更低密度影斑痕强化不明显,3例可见供血动脉,2例病灶边缘有斑块状强化,1例强化不明显。静脉期6例呈稍高密度,4例为等密度,2例为高低混合密度影。延迟期12例均低于肝脏密度呈较低密度。结论CT多期增强扫描对肝脏局灶性结节增生的诊断具有特征性,且较准确,对临床治疗具有指导意义。     

Telangiectatic focal nodular hyperplasia: US,CT, and MR imaging findings with histopathologic correlation in 13 cases

PURPOSE: To review the ultrasonographic (US), computed tomographic (CT), and magnetic resonance (MR) imaging findings in 13 patients with telangiectatic focal nodular hyperplasia (FNH) and to compare imaging features with histopathologic results from resected specimens. MATERIALS AND METHODS: US, helical multiphasic CT, and MR images in 13 patients with pathologically proven telangiectatic FNH were reviewed retrospectively. Two abdominal radiologists evaluated lesions for number, size, heterogeneity, surface characteristics, presence of a central scar, presence of a pseudocapsule, US appearance, attenuation at CT, signal intensity at MR imaging, and presence of associated lesions. Imaging and pathologic findings were compared. RESULTS: Sixty-one lesions (5-140 mm in diameter) were seen at imaging. Lesions were multiple in eight of 13 (62%) patients. Imaging characteristics were heterogeneity in 26 of 61 lesions (43%), well-defined margins in 43 of 61 (70%), lack of a central scar in 56 of 61 (92%), presence of a pseudocapsule in three of 61 (5%), hyperintensity on T1-weighted MR images in 17 of 32 (53%), strong hyperintensity on T2-weighted MR images in 24 of 54 (44%), and persistent enhancement on delayed contrast material-enhanced CT or T1-weighted MR images in 23 of 38 (61%). No specific US pattern was noted. Two patients had additional lesions: One had classic FNH, and the other had a cavernous hemangioma. Hyperintensity on T1-weighted MR images was due to sinusoidal dilatation. Hyperintensity on T2-weighted MR images correlated well with the presence of inflammation. CONCLUSION: Telangiectatic FNH differs from typical FNH at imaging: Atypical FNH features often observed with telangiectatic FNH are lack of a central scar, lesion heterogeneity, hyperintensity on T1-weighted MR images, strong hyperintensity on T2-weighted MR images, and persistent contrast enhancement on delayed contrast-enhanced CT or T1-weighted MR images.     

Early experience in the use of Levovist ultrasound contrast in the evaluation of liver masses

The aim of the present paper was to assess the utility of Levovist in defining the pathology of liver masses. Levovist is a new ultrasound contrast agent consisting of galactose microparticles, air bubbles and palmitic acid. Prospective studies were performed in patients referred for further evaluation of known liver masses. Levovist was peripherally injected and colour Doppler ultrasound studies were performed. Findings were correlated with clinicopathology and three other imaging modalities: biphasic spiral CT, CT arterial portography and contrast MRI. Twenty-five patients were studied (15 male and 10 female) in the age range 25-74 years. Liver masses ranged from 0.5 to 7 cm in maximum diameter. Thirteen lesions were benign and 12 were malignant (four hepatomas (HCC) and eight metastases). Levovist enhancement occurred in 18 lesions. Of these, six were benign (four focal nodular hyperplasias (FNH) and two haemangiomas). All 12 malignant lesions demonstrated enhancement. The HCC showed a mosaic pattern of central and peripheral enhancement, and the FNH demonstrated a spoke-wheel pattern. It was not possible to distinguish between haemangiomas and malignant lesions. Non-enhancing lesions may well be benign, with all malignancies showing some enhancement. Characteristic enhancement patterns were found for HCC (mosaic) and FNH (spoke-wheel). It was not possible to distinguish between metastases and benign lesions (haemangiomas) when the pattern of enhancement was peripheral.     

MSCT多期增强扫描对肝脏局灶性结节增生的诊断价值

目的:探讨MSCT多期增强扫描对肝脏局灶性结节增生(focal nodular hyperplasia,FNH)的诊断价值。方法:回顾性分析经手术及穿刺活检病理证实的9例FNH患者10个病灶的MSCT多期增强扫描表现。结果:9例中8例为单发病灶,1例多发。平扫9个呈低或稍低密度,1个等密度。平扫3个病灶见中央瘢痕;多期增强扫描7个病灶见中央瘢痕,动脉期及门脉期瘢痕均未见强化,延迟期5个见中央瘢痕强化。增强扫描动脉期除中央瘢痕外,8个FNH病灶明显均匀强化,2个中等均匀强化;门脉期病灶密度下降,但均略高于或等于正常肝实质;延迟期病灶密度等于或略低于肝实质。动脉期4个病灶中心或周边见增粗的供血动脉,其中1个为肝动脉分支直接进入病灶中心,1个的供血动脉自病灶中心沿纤维间隔向周边呈放射状分布,另2个周边见供血动脉。结论:MSCT多期扫描可反映病灶的血供特点和病理学特征,对FNH具有重要的诊断及鉴别诊断价值。     

螺旋CT多期扫描诊断肝脏局灶性结节增生研究

目的 探讨肝脏局灶性结节增生(FNH)的螺旋CT平扫和多期增强扫描表现特征,以提高CT对FNH的诊断准确性.资料与方法 回顾性分析16例经病理证实的FNH患者螺旋CT平扫及动脉期、门静脉期、延迟期增强扫描的资料.结果 16例患者16个FNH病灶中,平扫显示所有病灶均为略低密度,位于肝包膜下,其中14个可见更低密度瘢痕,从病灶中心向周围呈辐射状或不规则状.肿块实质呈"快进慢出"强化,中心瘢痕及辐射状分隔、假包膜"延迟强化",延迟期整个肿块密度趋于均匀一致.结论 平扫和多期增强螺旋CT扫描能全面显示FNH的病理特征及血流动力学特点,螺旋CT多期扫描有助于FNH的诊断及鉴别诊断.     

肝脏局灶性结节性增生2例报告及文献复习

目的通过分析肝脏局灶性结节增生的影像表现，提高其诊断准确性。方法2例经手术病理证实的肝脏局灶性结节增生患者均接受超声、CT和MRI检查，其影像表现结合文献复习进行了分析。结果超声显示了2例的肝右叶实性占位性病变。1例CT平扫肝右叶病灶显示不清，增强扫描后，肝右叶前段有一直径约3．1cm的类圆形病灶呈均匀强化。MR平扫见2例的肝内结节病灶均呈等T1、等T2信号，增强扫描动脉期病灶明显强化，门脉期和延迟期病灶的强化程度逐渐下降。结论腹部超声可提示本病的诊断，而CT和MRI，尤其是增强扫描，可清晰显示病灶的血供特点和强化特征，为定性诊断提供重要依据。     

Gadoxetic acid-enhanced high temporal-resolution hepatic arterial-phase imaging with view-sharing technique: Impact on the LI-RADS category

PurposeTo evaluate the value of view-sharing multi-hepatic arterial-phase (mHAP) imaging for diagnosis of hypervascular hepatocellular carcinoma (HCC).Materials and methodsForty-seven consecutive patients with HCC underwent gadoxetic acid-enhanced magnetic resonance (MR) imaging before angiographic and lipiodol CT. Hepatic arterial-phase images were obtained at 5 consecutive phases with shared central k-space of 25%, followed by portal venous, late (2 and 3 min), and hepatobiliary phase imaging. One-hundred-eight HCC nodules (size: 5–88 mm, mean size: 18.2 mm) confirmed on angiographic CT and lipiodol CT were evaluated for LI-RADS category and compared with single arterial-phase and mHAP findings regarding wash out, capsule, corona enhancement, and image quality.ResultsTwenty-four HCCs (22.2%) (size: 6–19 mm, mean size: 12.3 mm) were categorized as LR-3 based on the single arterial-phase. Capsule appearance (25.9%) and washout (57.4%) were most frequently observed in late phase (2 min). Corona enhancement was observed in 73.1% of all HCCs on mHAP. For the 24 HCCs of LR-3, corona enhancement was observed in 75% on mHAP and contributed to upgrade category. No significant difference was found in the frequency of corona enhancement between mHAP and angiographic CT (P = 0.11). Image quality was valued as good or excellent in all cases.ConclusionView-sharing mHAP was feasible without compromising image quality and contributed to the improvement in diagnostic confidence for hypervascular HCC in gadoxetic acid-enhance MR imaging.