低浓度造影剂在标准体质量人群冠状动脉CTA检查中的应用

【目的】探讨低浓度碘对比剂配合低电压的前瞻性心电门控扫描在冠状动脉CT血管造影（CTA）检查中的应用价值。【方法】连续收集体质量指数（BM I）小于24 kg/m2的临床疑诊冠心病者59例,随机分为3组：A组（25例）及B组（14例）分别应用270 mgI/mL及320 mgI/mL的碘对比剂,管电压分别为80 kV和100 kV ,C组（20例）应用370 mgI/mL碘对比剂,管电压为120 kV。三组所有病例均采用心电门控触发序列扫描,有效辐射剂量（ED）,测量主动脉根部的平均CT值,并对所有病例的冠状动脉CTA图像质量进行评分。【结果】A组、B组和C组的ED分别为（2．00±0．56）、（2．51±0．52）及（4．17±1．55）mSv,三组间两两比较均有显著性差异（P ＜0．05）。A、B、C组主动脉根部增强程度分别为（486．8±113．980）HU、（407．43±83．63） HU、（439．73±72．12） HU ,经统计分析,仅A、B两组比较有统计学意义（t＝2．28,P ＜0．05）。A组、B组及C组分别显示225个、126个和180个冠脉节段,图像优秀率分别为94．67％、89．68％和95．56％,经统计学分析,B、C比较有统计学意义（χ2值为4．00,P ＜0．05）,A、B组和 A、C组比较均无统计学差异（χ2值分别为3．03和0．17,均P＞0．05）。【结论】对标准及低体质量人群应用低浓度碘对比剂同时采用低管电压冠状动脉CTA扫描,能够在获得满足诊断图像质量的前提下,大幅度降低碘注射量及辐射剂量。     

低浓度对比剂在冠状动脉CTA检查中的可行性研究

目的：探讨低浓度碘对比剂（270 mgI/mL）配合低管电压在冠状动脉CTA检查中的可行性。材料与方法：将90例行冠状动脉CTA检查的患者随机分为A组和B组。A组60例应用270 mgI/mL碘对比剂同时使用迭代算法重建,再将A组根据体质量指数（BMI）分为A1组（25例）及A2组（35例）,A1组（BMI〈24 kg/m2）管电压为80 kV,A2组（BMI≥24 kg/m2）管电压为100 kV;B组30例应用370 mgI/mL碘对比剂,120 kV管电压。两组均采用前瞻性心电门控扫描。记录扫描辐射剂量,并对图像质量进行主、客观分析。结果：平均有效辐射剂量（ED）A1组为（2.00±0.56） mSv,A2组为（2.35±0.74） mSv,B组为（3.98±1.78） mSv,A1组与B组间及A2组与B组间均有统计学差异（t值分别为-5.34和-4.95,P〈0.05）。图像质量方面,A1组与B组间及A2组与B组间主观评价优秀率无统计学差异（χ2值分别为1.10和2.04,P值均〉0.05）;客观评价图像噪声（SD）、信噪比（SNR）、对比噪声比（CNR）亦均无统计学差异。结论：应用尽可能低浓度的碘对比剂（270 mgI/mL）配合低管电压在冠状动脉CTA检查中是可行的,超重人群（BMI≥24 kg/m2）亦可应用,同时显著的降低了辐射剂量和碘注射量。     

SAFIRE重建在超重患者双源CT冠状动脉成像中的临床应用

目的与传统滤波反投影（FBP）重建比较,评价管电压100kV下双源CT（dual．sourceCT,DSCT）基于原始数据的迭代重建（SinogramAffirmedkerativeReconstruction,SAFIRE）在超重患者冠状动脉成像的应用价值。方法将80例体重指数（bodymassindex,BMI）处于超重患者（男性：25kg／m2≤BMI〈30kg／m2;女性：24kg／rn2≤BMI〈29kg／m2）行双源cT冠状动脉成像患者按扫描,管电压随机分成A组（120kV）、B组（100kV）,采用FBP重建,对B组采用SAFIRE重建得到C组图像。对三组的图像质量、平均CT值、图像噪声、信号噪声比（signal—to-noiseratio,SNR）、对比噪声比（contrast．to．noiseratio,CNR）及辐射剂量进行对比分析。结果三组图像质量分别为（3．51±0．70）分、（3．49±0．33）分和（3．55±0．47）分,差异无统计学意义（P〉0．05）;三组平均CT值、图像噪声、SNR及CNR比较差异均具有统计学意义（P〈0．05）;A组与B组（或C组）两组问平均CT值比较差异有统计学意义（P〈0．05）,且A组平均CT值最低。B组与A组（或c组）两组间图像噪声、SNR及CNR比较差异有统计学意义（尸〈0．05）,且A组较高。A、C两组间图像噪声、SNR及CNR比较差异无统计学意义（P〉0．05）;A、B组（或C组）辐射剂量比较差异有统计学意义（P〈0．05）,且B组（或C组）较A组辐射剂量下降约34％。结论对于超重患者,采用100kV管电压结合SAFIRE行冠状动脉CTA检查,可改善图像质量,显著降低辐射剂量。     

低管电压扫描技术联合低浓度对比剂在肾动脉CTA中的研究应用

目的：探索低管电压与低浓度对比剂的“双低”扫描方案在不具备迭代算法的CT机上行肾动脉CT血管造影（Com-puted tomography angiography,CTA）中的可行性.方法：将136例腹部CTA受检者按管电压和对比剂浓度随机分为4组.利用原始图像及后处理重建图像测量计算肾动脉的客观指标及辐射剂量结果.以Sahani 5分法评价肾动脉及分支血管显示程度.统计对比剂不良反应发生率.结果：4组之间两两比较,图像血管强化CT值及对比噪声比（CNR）值有显著性差异（P＜0.05）;管电压不同时,100 kV较120 kV背景值升高、噪声增大（P＜0.05）;肾动脉血管信噪比（SNR）值仅C组与D组比较无显著差异（P＝0.342）;图像质量主观评分差异无统计学意义（P＞0.05）;管电压不同时,100 kV较120 kV辐射剂量降低了约39％（P＜0.05）;不良反应发生率270 mgI/mL对比剂组较350 mgI/mL对比剂组明显减低（P＜0.05）.结论：使用低管电压、低浓度对比剂的扫描在不具备迭代算法的CT机上也可以获得满意的肾动脉CTA图像质量,同时降低了辐射剂量及对比剂不良反应发生率.     

糖化血红蛋白水平对冠心病合并2型糖尿病患者冠脉病变及急性心肌梗死发生率的影响

【目的】探讨分析糖化血红蛋白水平（HbA1c）对冠心病合并2型糖尿病患者冠脉病变特点及急性心肌梗死（AMI）发生率的影响。【方法】回顾性分析本院2012年1月至2013年2月间收治的150例经冠脉造影确诊为冠心病患者的临床资料,根据HbA1c水平将其分为三组：A组,45例（单纯冠心病患者,HbA1c＜5．7％）;B组,48例（合并2型糖尿病血糖控制良好组,HbA1c＜6．5％）;C组,57例（合并2型糖尿病血糖控制不佳组,HbA1c≥6．5％）。比较三组患者AMI发生率及冠脉病变特点有无差异。【结果】①C组A M I发病率显著高于A组和B组,差异均有统计学意义（分别为P＜0．001,P＜0．05）;B组AMI发病率显著高于A组（ P ＜0．05）。②B、C两组冠脉造影主要表现为多支、多节段弥漫性病变,A组冠脉造影主要表现为单支病变,其次为双支病变,B、C两组多支病变明显高于A组,差异具有统计学意义（ P ＜ 0．05）,B、C两组冠脉病变支数无统计学意义（ P ＞0．05）,三组病变的血管分布无统计学意义（ P ＞0．05）。③三组Gensini积分差异显著,具有统计学意义（ P ＜0．05）。【结论】冠心病合并2型糖尿病患者 HbA1c水平控制不佳会增加AMI发病率,加重冠脉病变严重程度。     

能谱CT双低剂量在头颈联合血管成像中的临床初探VascularimagingofheadandneckbydoublelowdoseCT:aprimaryclinicalstudy

目的：评估宝石CT低千伏及低浓度对比剂（双低）对头颈联合CTA图像质量和辐射剂量的影响。方法：选取我院行头颈联合CTA患者120例,随机分成两组,各60例。A组：管电压100 kVp,对比剂（威视派克270 mgI/mL）。B组：管电压120 kVp,对比剂（欧乃派克350 mgI/mL）。图像重建使用自适应统计迭代算法（ASiR）,其它扫描参数不变。记录图像最佳对比噪声比、颈动脉CT均值和噪声值、辐射剂量及平均碘摄入量。由两位放射医师用4分制评估图像质量,利用SPSS统计软件对数据进行T检验。结果：①A组图像对比噪声比高于B组（A组：15.23±2.10;B组：13.42±1.93,t=4.91,P<0.001）。②两组图像噪声和图像质量评分（分别为9.45±1.04和3.64±0.49分,9.38±0.97和3.52±0.48分,P均>0.05）差异无统计学意义。③A组颈动脉平均CT值（（406.4±48.2） HU）高于B组（（385.1±44.4） HU）（t=10.45,P＜0.001）。④A组辐射剂量明显低于B组,降低约35%（（2.59± 0.30） mSv和（4.02±0.58） mSv,t=17.02,P＜0.001）,差异有统计学意义。⑤A组人均对比剂碘摄入量（（230.42±5.04） mgI/kg）低于B组（303.34±7.34） mgI/kg）（t=63.46,P＜0.001）。结论：宝石CT头颈联合血管成像使用管电压100 kVp及低浓度对比剂270 mgI/mL可以提供更好的图像对比噪声比,保证诊断图像质量的同时明显的降低辐射剂量,同时减少了对比剂碘的摄入,对潜在肾功能损害的患者是一个较好的选择。     

能谱CT在100 kVp和80 kVp时肺动脉血管造影的图像质量和辐射剂量的评估

目的：比较能谱CT在100 kVp和80 kVp时肺动脉血管造影的图像质量和辐射剂量,对80 kVp条件下使用低浓度对比剂（碘克沙醇270 mgI/mL）的可行性进行评估.方法：将60例行肺动脉CT血管造影的患者分为3组各20例.A组：管电压100 kVp,使用对比剂320 mgI/mL.B组：管电压80 kVp,使用对比剂320 mgI/mL.C组：管电压80 kVp,使用对比剂270 mgI/mL.图像重建使用自适应统计迭代算法（ASiR）,3组对比剂用量相同.以肺动脉CT值的标准差作为图像噪声,用肺动脉主干与竖脊肌CT值计算图像对比噪声比,记录容积CT剂量指数和肺动脉各级分支CT值并取均值,由3个独立的放射医师对图像质量进行评分.对3组数据进行统计学分析.结果：①图像噪声各组之间无统计学差异（P＞0.05）.对比噪声比各组之间没有显著差异（A组37.0±11.1,B组32.4±9.5,C组34.3±10.4,P=-0.1 1）.②B组和C组的容积CT剂量指数（（4.6±0.2）mGy和（4.3±0.4）mGy）与A组相比（（6.4±0.6）mGy）,分别减少了28％和32.9％（P＜0.001）.③B组肺动脉各级分支血管CT值明显高于A组和C组（P＜0.001）.④3组图像质量评分没有统计学差异（P=-0.92）.⑤C组人均对比剂碘摄入量（154 mgI/kg）低于A和B组（182 mgI/kg）（P＜0.05）.结论：肺动脉CT血管造影管电压从100 kVp降低到80 kVp,在不影响图像质量的同时显著降低了辐射剂量,80 kVp条件下使用低浓度等渗对比剂可以达到诊断图像质量的要求.     

低辐射剂量低对比剂浓度在320排CT冠脉成像中的应用

目的：探讨低辐射剂量低对比剂浓度冠脉成像的可行性.方法：对临床拟诊为冠心病的200例患者随机分为A、B、C3组,A组（120 kV,270 mgI/mL）65例,B组（120 kV,350 mgI/mL）65例,C组（100 kV,270 mgI/mL） 70例.采用320排CT行前瞻性心电门控扫描,评价试验所得到的3组图像质量以及患者所接受的有效辐射剂量.结果：3组图像冠脉评分无显著差异（P＞0.5）,图像噪声和增强效果有明显差异（P＜0.05）,但都可满足诊断.患者所接受的辐射剂量有显著差异（P＜0.01）,C组是其中的最低值组.结论：低辐射剂量低对比剂浓度可用于CT冠脉成像,并且具有明显的优越性.     

早期抚触联合高压氧或水疗对重度新生儿缺氧缺血性脑病近期神经运动功能的影响

【目的】探讨早期抚触联合高压氧疗、水疗对重度新生儿缺氧缺血性脑病（HIE）近期神经运动功能的影响。【方法】收集 H IE患儿497例,按照治疗方法分为A、B、C三组,A组采用单纯早期抚触,B组抚触联合高压氧疗,C组采用抚触联合水疗。对比三组患儿运动功能、神经20项评分标准（NBNA）评分及治疗后体质量、身高、每日摄奶量情况。【结果】治疗后A组完成Ⅲ级动作比例明显低于B组和C组（P＜0．05）,其中B组与C组相比差异无统计学意义（ P＞0．05）;治疗2周、4周后B组、C组NBNA评分显著高于A组（ P＜0．05）,其中B、C两组间相比NBNA评分差异无统计学意义（P＞0．05）;治疗4周后B组、C组患儿体质量、身高、每日摄奶量均显著优于A组（P ＜0．05）,B、C组两两相比差异无统计学意义（P ＞0．05）。【结论】早期抚触联合高压氧或水疗均可以促进HIE患儿神经运动功能的康复,有利于新生儿的生长、发育,值得临床推广应用。     

70 kVp超低辐射剂量和低碘摄入量在低体质量指数患者腹部CTA的可行性

目的 探讨70 kVp在低体质量指数（BMI;BMI≤22 kg/m²）患者腹部CTA中降低辐射剂量和碘摄入量的可行性。方法 收集临床拟诊腹部血管疾病而行全腹部CTA检查、BMI ≤ 22kg/m²的患者48例,按管电压和对比剂摄入量分为2组,A组27例,采用70 kVp（对比剂300 mgI/kg体质量）;B组21例,采用120 kVp（对比剂500 mgI/kg体质量）;其余参数两组相同;对比剂均采用350 mgI/ml的碘海醇。2名观察者分别以5分制对两组右肾动脉图像质量进行评分,对评分行一致性检验,比较两组主观评分差异性;测量A、B组的腹主动脉、腹腔干、肠系膜上动脉、肝总动脉、脾动脉的CT值及同层面竖脊肌的CT值和SD值（噪声）。比较两组上述动脉CT值、腹主动脉SNR和CNR;比较两组容积CT剂量指数（CTDI_vol）和剂量长度乘积（DLP）及患者总摄碘量。结果 2名观察者对两组右肾动脉图像评分中位数均为5.00（1.00）分,差异无统计学意义（P>0.05）,一致性很好（Kappa=0.932、0.911）;A组腹主动脉、腹腔干、肠系膜上动脉、肝总动脉、脾动脉的CT值均高于B组,差异均有统计学意义（P均<0.05）;A组腹主动脉SNR、CNR均高于B组,差异有统计学意义（P<0.05）;A、B组CTDI_vol和DLP的差异均有统计学意义,A组CTDI_vol较B组降低73.36%、DLP降低74.41%;A、B组患者总碘摄入量分别为（46.33±6.43）ml、（84.31±10.71）ml,A组较B组每例患者总碘摄入量降低45.05%。结论 针对BMI≤ 22 kg/m²患者,采用70 kVp低管电压行腹部CTA扫描,可显著提高腹主动脉及其分支的图像CNR和SNR,同时明显降低辐射剂量及患者摄入总碘量,具有很好的临床推广价值。     

Determination of creatine kinase isoenzyme MB activity in serum using immunological inhibition of creatine kinase M subunit activity. Activity kinetics and diagnostic significance in myocardial infarction.

This is a new method for the determination of creatine kinase isoenzyme MB activity in serum. The method uses direct activity measurement of creatine kinase B subunit activity after blocking of CK-M subunit activity by inhibiting antibodies. The test takes no longer than 15 min. The method yields an intra-serial C.V. of 2.0-12.9%, and a C.V. from day to day of 5.5%. The detection limit is 3.4 U/l creatine kinase MB. In the 95 cases with proven myocardial infarction several types of creatine kinase MB activity kinetics could be determined. The percentage of creatine kinase MB of peak CK-total is 6-25%, with a mean of 11.1%. The amount of creatine kinase MB with respect to total CK activity after reinfarction is higher than the amount after initial infarction.     

Dissociable correlates of two classes of retrieval processing in prefrontal cortex

Although substantial evidence suggests that the prefrontal cortex (PFC) implements processes that are critical for accurate episodic memory judgments, the specific roles of different PFC subregions remain unclear. Here, we used event-related functional magnetic resonance imaging to distinguish between prefrontal activity related to operations that (1) influence processing of retrieval cues based on current task demands, or (2) are involved in monitoring the outputs of retrieval. Fourteen participants studied auditory words spoken by a male or female speaker and completed memory tests in which the stimuli were unstudied foil words and studied words spoken by either the same speaker at study, or the alternate speaker. On "general" test trials, participants were to determine whether each word was studied, regardless of the voice of the speaker, whereas on "specific" test trials, participants were to additionally distinguish between studied words that were spoken in the same voice or a different voice at study. Thus, on specific test trials, participants were explicitly required to attend to voice information in order to evaluate each test item. Anterior (right BA 10), dorsolateral prefrontal (right BA 46), and inferior frontal (bilateral BA 47/12) regions were more active during specific than during general trials. Activation in anterior and dorsolateral PFC was enhanced during specific test trials even in response to unstudied items, suggesting that activation in these regions was related to the differential processing of retrieval cues in the two tasks. In contrast, differences between specific and general test trials in inferior frontal regions (bilateral BA 47/12) were seen only for studied items, suggesting a role for these regions in post-retrieval monitoring processes. Results from this study are consistent with the idea that different PFC subregions implement distinct, but complementary processes that collectively support accurate episodic memory judgments.     

俯卧位通气对高海拔地区肺复张治疗无效急性呼吸窘迫综合征患者氧合的影响

目的 探讨俯卧位通气对高海拔地区肺复张术(RM)治疗无效急性呼吸窘迫综合征(ARDS)患者的治疗作用.方法 从海拔2260m的地区医院筛选RM治疗无效的41例ARDS患者[平均氧合指数( PaO2/FiO2)较RM前升高＜20％视为RM无效],依不同病因分为肺内源性ARDS组(ARDSp组)和肺外源性ARDS组(ARDSexp组),每组再按信封法随机分为俯卧位组和仰卧位组,即ARDSp俯卧位组(11例)、ARDSp仰卧位组(9例)、ARDSexp俯卧位组(10例)、ARDSexp仰卧位组(11例).在通气前及通气1、2、3、4h监测动脉血氧分压( PaO2)、PaO2/FiO2、静态顺应性(Cst)、气道阻力(Raw)的变化.结果 通气lh时,ARDSexp俯卧位组PaO2/FiO2( mm Hg,l mm Hg=0.133 kPa)即较通气前显著升高(157.4±40.6比129.3±48.7,P＜0.05),并随通气时间延长呈持续增高趋势,4h达峰值(219.1 ±41.1);且ARDSexp俯卧位组通气3h内PaO2/FiO2较其他3组显著增高,另3组间则差异无统计学意义.ARDSp俯卧位组、ARDSexp俯卧位组通气4h时PaO2/FiO2均较相应仰卧位组显著增高(208.8±39.7比127.4±47.1,219.1±41.1比124.9±50.8,均P＜0.05).4组通气前后Cst无显著改变,各组间差异也无统计学意义.ARDSp俯卧位组通气4h时Raw(cmH2O·L-1·s-1)较通气前显著降低(6.8±1.7比10.7±1.8,P＜0.05),且明显低于其他3组;其他3组各时间点Raw组内及组间比较差异均无统计学意义.结论 俯卧位通气作为ARDS机械通气重要策略之一,可以改善RM无效高原ARDS患者的氧合,为抢救患者赢得宝贵的时间.     

Digital imaging among medical facilities

The Department of Veterans Affairs (VA) in the USA operates a network of 172 medical centres which all utilize a hospital information system (HIS) which has been developed and is currently maintained by the VA. During the past several years, an image management and communication module has been developed, installed and clinically utilized at the Washington DC and Maryland VA Medical Centres. This image management and communication system, referred to as the decentralized hospital computer program (DHCP) imaging system, is fully integrated with a commercial picture archiving and communication system (PACS). The system is utilized to capture, archive, and display all images generated within the hospital including radiology, nuclear medicine, pathology, endoscopy, bronchoscopy, and dermatology, intraoperative photographs, ECG data, and a limited number of paper documents. The ultimate goal of the project is to have all patient text and image data available at any clinical workstation to any authorized user anywhere within the network of medical centres. Clinical requirements for an imaging workstation include ease of use, rapid and reliable access to the complete set of patient information, and images which are of acceptable quality to meet the requirements of the user and the subspecialty. Patient confidentiality and data security must be safeguarded at all times. Integration of the images with the remainder of the patient's database was found to be critical to the success of the project. The experience at the Washington and Maryland facilities suggests that an imaging system that is successfully integrated with a hospital information system can provide substantial clinical and economic benefits both within and among medical centres. Clinical acceptance and utilization of the system has been excellent, particularly in diagnostic radiology where DHCP Imaging has been interfaced to a commercial PAC system. Based upon this initial experience, the VA has begun to deploy the system throughout its large network of medical centres.     

Myocardial elastography at both high temporal and spatial resolution for the detection of infarcts

Myocardial elastography is a novel method for noninvasively assessing regional myocardial function, with the advantages of high spatial and temporal resolution and high signal-to-noise ratio (SNR). In this paper, in-vivo experiments were performed in anesthetized normal and infarcted mice (one day after left anterior descending coronary artery [LAD] ligation) using a high-resolution (30 MHz) ultrasound system (Vevo 770, VisualSonics Inc., Toronto, ON, Canada). Radiofrequency (RF) signals of the left ventricle (LV) in longitudinal (long-axis) view and the associated electrocardiogram (ECG) were simultaneously acquired. Using a retrospective ECG gating technique, 2-D full field-of-view RF frames were acquired at an extremely high frame rate (8 kHz) that resulted in high-quality incremental displacement and strain estimation of the myocardium. The incremental results were further accumulated to obtain the cumulative displacements and strains. Two-dimensional and M-mode displacement images and strain images (elastograms), as well as displacement and strain profiles as a function of time, were compared between normal and infarcted mice. Incremental results clearly depicted cardiac events including LV contraction, LV relaxation and isovolumetric phases in both normal and infarcted mice, and also evidently indicated reduced motion and deformation in the infarcted myocardium. The elastograms indicated that the infarcted regions underwent thinning during systole rather than thickening, as in the normal case. The cumulative elastograms were found to have higher elastographic SNR (SNR(e)) than the incremental elastograms (e.g., 10.6 vs. 4.7 in a normal myocardium, and 6.0 vs. 2.4 in an infarcted myocardium). Finally, preliminary statistical results from nine normal (m = 9) and seven infarcted (n = 7) mice indicated the capability of the cumulative strain in differentiating infracted from normal myocardia. In conclusion, myocardial elastography could provide regional strain information at simultaneously high temporal (>/=0.125 ms) and spatial ( approximately 55 microm) resolution as well as high precision ( approximately 0.05 microm displacement). This technique was thus capable of accurately characterizing normal myocardial function throughout an entire cardiac cycle, at the same high resolution, and detecting and localizing myocardial infarction in vivo.     

手转胎头术失败的原因与分娩结局临床分析

目的 探讨手转胎头术失败的原因与分娩结局.方法 选择2008年1月至2010年12月于我院住院分娩的持续性枕横位、枕后位产妇198例,根据行手转胎头术后结果分为成功组126例、失败组72例.比较两组分娩结局,对比分析失败原因.结果 失败组胎儿体质量≥3500 g的发生率[76.4％(55/72)]明显高于成功组[31.7％(40/126)],差异有统计学意义(x2=30.177,P=0.001)、失败组宫缩乏力发生率[58.3％(42/72)]高于成功组[38.1％ (48/126)],差异有统计学意义(x2=7.569,P=0.006)、失败组骨盆临界或轻度狭窄发生率[38.9％ (28/72)]高于成功组[23.8％(30/126)],差异有统计学意义(x2 =5.030,P=0.002)、失败组手转胎头时机不当(宫口开大＜6 cm、胎头位于坐骨棘上及宫口开大8～10 cm、胎头位于坐骨棘下≥2 cm)发生率[61.1％(44/72)]高于成功组[38.9％(49/126)],差异有统计学意义(x2=9.084,P=0.003).失败组母儿并发症(产后出血、产褥病率、胎儿窘迫、新生儿窒息)发生率高于成功组(x2 =9.586,P=0.002、x2=9.334,P=0.002、x2=5.910,P=0.015、x2=5.240,P=0.022)、失败组剖宫产发生率[72.2％(52/72)]明显高于成功组[34.1 ％(43/126),x2=26.641,P=0.001)].结论 手转胎头术能使难产变顺产,降低剖宫产率,减少母儿并发症,但须积极预防、处理导致手转胎头术失败的原因,对矫正失败后继续矫正及试产应慎重.