共查询到20条相似文献,搜索用时 31 毫秒
1.
Wilhelm-Benartzi CS Christensen BC Koestler DC Andres Houseman E Schned AR Karagas MR Kelsey KT Marsit CJ 《Cancer causes & control : CCC》2011,22(8):1205-1213
Background
The association between secondhand smoke (SHS) exposure and bladder cancer is inconclusive. Epigenetic alterations in bladder tumors have been linked to primary cigarette smoking and could add to the biological plausibility of an association between SHS exposure and bladder cancer. 相似文献2.
Mona S?b? Camilla F Skjelbred Rebecca Breistein Inger Marie B Lothe Per Chr Hagen Gunter Bock Inger-Lise Hansteen Elin H Kure 《BMC cancer》2006,6(1):71
Background
The association between colorectal cancer (CRC) and smoking has not been consistent. Incomplete smoking history and association to a specific subset of CRC tumors have been proposed as explanations. The adenomatous polyposis coli (APC) gene has been reported to have a "gatekeeper" function in the colonic mucosa. 相似文献3.
Andrew Flood Lori Strayer Catherine Schairer Arthur Schatzkin 《Cancer causes & control : CCC》2010,21(8):1277-1284
Objective
To determine whether accounting for the time dynamics of diabetes exposure will change the risk estimates for colorectal cancer. 相似文献4.
Y. Chaiter S. B. Gruber A. Ben-Amotz R. Almog H. S. Rennert R. Fischler G. Rozen G. Rennert 《Cancer causes & control : CCC》2009,20(8):1327-1338
Objectives
Consumption of vegetables and fruits, physical activity, obesity and caloric intake are all strongly related to the risk of colorectal cancer (CRC). The association between dietary intake of carotenoids from vegetables/fruits and risk of CRC in the context of cigarette smoking was studied in a nutritionally diverse population. 相似文献5.
Objective
Although causal relationships between smoking and cancer risk have been established for many sites, most studies of brain cancer have not supported an association. However, two recent cohort studies showed increased risks of glioma among smokers. We quantified the association between smoking and glioma through a meta-analysis of the literature. 相似文献6.
Fernando Martínez Carlos Fernández-Martos María Jesús Quintana Antoni Castells Antonio Llombart Francisco Iñiguez Vicente Guillem Francisco Dasí 《Clinical & translational oncology》2011,13(9):664-671
Background
The purpose of this study was (a) to evaluate the association between cigarette smoking and the prevalence of distal colorectal polyps and adenocarcinoma and (b) to analyse genetic alterations representing different molecular pathways of the colorectal carcinogenesis. 相似文献7.
BACKGROUND:
Smoking and alcohol consumption are associated with an increased risk of developing colorectal cancer. However, it is unclear whether these exposures are associated with survival after colorectal cancer diagnosis.METHODS:
Men and women diagnosed with incident colorectal cancer between 1998 and 2007 in 13 counties in western Washington State were identified by using the Surveillance, Epidemiology, and End Results cancer registry. Information on smoking history and alcohol consumption was collected by telephone interview. Follow‐up for mortality was completed through linkage to the National Death Index. Cox proportional hazards regression was used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations among smoking, alcohol consumption, and mortality after colorectal cancer diagnosis. Stratified analyses were conducted by sex, age at diagnosis (<50 years, ≥50 years), tumor site (proximal, distal, rectal), stage (I‐II, III‐IV), and microsatellite instability status (stable/low, high).RESULTS:
Disease‐specific and all‐cause mortality were significantly higher for smokers (HR, 1.30; 95% CI, 1.09‐1.74) compared with never‐smokers (HR, 1.51; 95% CI, 1.24‐1.83). However, this association was most prominent in those with tumors exhibiting high microsatellite instability (HR, 3.83; 95% CI, 1.32‐11.11) and did not extend to those with rectal cancer (HR, 1.08; 95% CI, 0.72‐1.61) or those diagnosed before age 50 years (HR, 0.99; 95% CI, 0.67‐1.48). Alcohol consumption was not associated with disease‐specific or all‐cause mortality, regardless of patient or tumor characteristics.CONCLUSIONS:
In addition to an association with disease risk, smoking is associated with increased mortality after colorectal cancer diagnosis. This association is especially pronounced for colorectal cancer with high microsatellite instability. Cancer 2011;. © 2011 American Cancer Society. 相似文献8.
Tsilidis KK Allen NE Key TJ Bakken K Lund E Berrino F Fournier A Olsen A Tjønneland A Overvad K Boutron-Ruault MC Clavel-Chapelon F Byrnes G Chajes V Rinaldi S Chang-Claude J Kaaks R Bergmann M Boeing H Koumantaki Y Stasinopoulou G Trichopoulou A Palli D Tagliabue G Panico S Tumino R Vineis P Bueno-de-Mesquita HB van Duijnhoven FJ van Gils CH Peeters PH Rodríguez L González CA Sánchez MJ Chirlaque MD Barricarte A Dorronsoro M Borgquist S Manjer J van Guelpen B Hallmans G Rodwell SA Khaw KT 《British journal of cancer》2010,103(11):1755-1759
Background:
Oral contraceptive use and reproductive factors may initiate long-term changes to the hormonal milieu and thereby, possibly influence colorectal cancer risk.Methods:
We examined the association of hormonal and reproductive factors with risk of colorectal cancer among 337 802 women in the European Prospective Investigation into Cancer and Nutrition, of whom 1878 developed colorectal cancer.Results:
After stratification for center and age, and adjustment for body mass index, smoking, diabetes mellitus, physical activity and alcohol consumption, ever use of oral contraceptives was marginally inversely associated with colorectal cancer risk (hazard ratio (HR), 0.92; 95% confidence interval (CI), 0.83–1.02), although this association was stronger among post-menopausal women (HR, 0.84; 95% CI: 0.74–0.95). Duration of oral contraceptive use and reproductive factors, including age at menarche, age at menopause, type of menopause, ever having an abortion, parity, age at first full-term pregnancy and breastfeeding, were not associated with colorectal cancer risk.Conclusion:
Our findings provide limited support for a potential inverse association between oral contraceptives and colorectal cancer risk. 相似文献9.
Josh Squires Barbara Roebothan Sharon Buehler Zhuoyu Sun Michelle Cotterchio Ban Younghusband Elizabeth Dicks John R. Mclaughlin Patrick S. Parfrey Peizhong Peter Wang 《Cancer causes & control : CCC》2010,21(9):1513-1521
Objective
Although a large body of epidemiological research suggests that red meat intake increases the risk of colorectal cancer, little is known regarding how such an association varies across populations and types of red meat. The objective of this study was to assess whether an association exists between the intakes of total red meat and pickled red meat and the risk of colorectal cancer in study subjects residing in Newfoundland and Labrador. 相似文献10.
Park ER Japuntich SJ Rigotti NA Traeger L He Y Wallace RB Malin JL Zallen JP Keating NL 《Cancer》2012,118(12):3153-3164
BACKGROUND:
Continued smoking after a cancer diagnosis may adversely affect treatment effectiveness, subsequent cancer risk, and survival. The prevalence of continued smoking after cancer diagnosis is understudied.METHODS:
In the multi‐regional Cancer Care Outcomes Research and Surveillance cohort (lung cancer [N = 2456], colorectal cancer [N = 3063]), the authors examined smoking rates at diagnosis and 5 months after diagnosis and also study factors associated with continued smoking.RESULTS:
Overall, 90.2% of patients with lung cancer and 54.8% of patients with colorectal cancer reported ever smoking. At diagnosis, 38.7% of patients with lung cancer and 13.7% of patients with colorectal cancer were smoking; whereas, 5 months after diagnosis, 14.2% of patients with lung cancer and 9.0% of patients with colorectal cancer were smoking. Factors that were associated independently with continued smoking among patients with nonmetastatic lung cancer were coverage by Medicare, other public/unspecified insurance, not receiving chemotherapy, not undergoing surgery, prior cardiovascular disease, lower body mass index, lower emotional support, and higher daily ever‐smoking rates (all P < .05). Factors that were associated independently with continued smoking among patients with nonmetastatic colorectal cancer were male sex, high school education, being uninsured, not undergoing surgery, and higher daily ever‐smoking rates (all P < .05).CONCLUSIONS:
After diagnosis, a substantial minority of patients with lung and colorectal cancers continued smoking. Patients with lung cancer had higher rates of smoking at diagnosis and after diagnosis; whereas patients with colorectal cancer were less likely to quit smoking after diagnosis. Factors that were associated with continued smoking differed between lung and colorectal cancer patients. Future smoking‐cessation efforts should examine differences by cancer type, particularly when comparing cancers for which smoking is a well established risk factor versus cancers for which it is not. Cancer 2012;118: 3153–64. © 2012 American Cancer Society. 相似文献11.
Konstantinos K. Tsilidis Frederick L. Brancati Michael N. Pollak Nader Rifai Sandra L. Clipp Judith Hoffman-Bolton Kathy J. Helzlsouer 《Cancer causes & control : CCC》2010,21(1):1-10
Background
Metabolic syndrome components have been associated with colorectal cancer in several studies; however, evidence for colorectal adenomas is limited. Thus, we evaluated the association between markers of the metabolic syndrome with colorectal adenoma development in a nested case–control study. 相似文献12.
Background
Activation of the ras genes or association with human papillomavirus infection have been extensively studied in colorectal cancer. However, the correlation between K-ras mutations and HPV in colorectal cancer has not been investigated yet. In this study we aimed to investigate the presence of K-ras mutations and their correlation with HPV infection in colon cancer. 相似文献13.
Sekwon Jang Anna Prizment Tufia Haddad Kim Robien DeAnn Lazovich 《Journal of cancer survivorship》2011,5(2):115-122
Purpose
To examine the association of smoking and quality of life (QOL) among survivors of breast, colorectal, or endometrial cancers. 相似文献14.
Jennifer Lin Robert Y. L. Zee Kuang-Yu Liu Shumin M. Zhang I-Min Lee JoAnn E. Manson Edward Giovannucci Julie E. Buring Nancy R. Cook 《Cancer causes & control : CCC》2010,21(6):897-908
Objectives
Several lines of evidence have suggested that female hormones may lower the risk for developing colorectal cancer. However, the mechanisms by which sex hormones affect colorectal cancer development remain unknown. We sought to determine whether the association may be under genetic control by evaluating genetic variation in estrogen receptors (ESR1 and ESR2), progesterone receptor (PGR), aromatase cytochrome 450 enzyme (CYP19A1), and 17 beta-hydroxysteroid dehydrogenase type 2 gene (HSD17B2). 相似文献15.
Chunhui Zhang Li Hao Liang Wang Yichuan Xiao Hailiang Ge Zhenya Zhu Yunbao Luo Yi Zhang Yanyun Zhang 《BMC cancer》2010,10(1):184
Background
Insulin-like growth factor-I receptor (IGFIR) has been shown to regulate the tumor development. The objective of the current study is to determine the association of IGFIR with lymph node metastasis and to explore the related mechanism in human colorectal cancer in clinic. 相似文献16.
Background
Gastric cancer is the fourth most frequently occurring malignancy after lung, breast, and colorectal cancer, and the second most common cause of death from cancer worldwide. Epidemiologic studies have examined the possible association between fish consumption and gastric cancer, but the results were inconclusive. We conducted a systematic review and meta-analysis to examine the association between fish intake and the risk of gastric cancer. 相似文献17.
Shigeyuki Nakaji Tadashi Shimoyama Takashi Umeda Juichi Sakamoto Shuji Katsura Kazuo Sugawara David Baxter 《BMC cancer》2001,1(1):14-6
Background
Since Fuchs' report in 1999, the reported protective effect of dietary fiber from colorectal carcinogenesis has led many researchers to question its real benefit. The aim of this study is to evaluate the association between diet, especially dietary fiber and fat and colorectal cancer in Japan. 相似文献18.
Chunhong Fan Mingjuan Jin Kun Chen Yongjing Zhang Shuangshuang Zhang Bing Liu 《BMC cancer》2007,7(1):115
Background
Gene-gene and gene-environment interactions involved in the metabolism of carcinogens may increase the risk of cancer. Our objective was to measure the interactions between common polymorphisms of P450 (CYP1A2, CYP1B1, CYP2E1), GSTM1 and T1, SULT1A1 and cigarette smoking in colorectal cancer (CRC). 相似文献19.
Background
A number of studies has evaluated the association between P53 codon 72 polymorphism and colorectal cancer. However, results were inconsistent. To clarify the role of this polymorphism in colorectal cancer, we conducted a meta-analysis on this topic.Methods
Two authors independently searched the PubMed and EMBASE database from 1966 to January 2010 for studies regarding the association of P53 codon 72 polymorphism with colorectal cancer. Summary odds ratios with their corresponding 95% confidence intervals were calculated by using random-effects model.Results
The combined results showed that P53 codon 72 variant genotypes were not associated with colorectal cancer risk when compared to Arg/Arg genotype (Pro/Pro: OR = 1.02, 95% CI = 0.80–1.29; Arg/Pro: OR = 1.00, 95% CI = 0.86–1.16; Pro allele: OR = 1.00, 95% CI = 0.86–1.17). When stratifying for study population, design and cancer location, no statistically significant results were observed either.Conclusion
Our data indicate that the P53 codon 72 polymorphism may be not associated with colorectal cancer risk. 相似文献20.
Zhao Z Pelletier E Barber B Bhosle M Wang S Klingman D Gao S 《Journal of gastrointestinal cancer》2012,43(3):456-461