3，6－二［二甲氨基］－二苯骈碘杂环枸橼酸盐（IHC－65）的镇痛和镇静作用

 采用扭体、热板及足跖刺激法，对碘杂环－65（IHC－65）的镇痛作用进行了研究。结果表明：ivIHC－653．75和7．5mg／kg对小鼠扭体反应均有抑制作用（P＜0．05和p＜0．01），并能显著提高热板法致痛小鼠的痛阈值。作用开始时间均为给药后30min，作用维持时间分别为30和90min，但对足跖刺激法致痛小鼠痛阈无明显影响。icvIHC－657．5μg／只，15和30min后也有镇痛作用，提示其镇痛作用部位在中枢，此外ipIHC－65还能明显减少小鼠自发活动次数。     

疏风清热胶囊的主要药效学研究

将３．０ｇ／ｋｇ，１．５ｇ／ｋｇ疏风清热胶囊混悬液给大鼠，小鼠灌胃给药，观察该药的抗炎，镇痛，解热作用，结果表明，疏风清热胶囊对二甲苯致小鼠耳壳炎症，大鼠蛋清性足跖肿胀有明显的抑制作用，对热板致痛和醋酸诱发小鼠扭体反应作用表明，１．５ｇ／ｋｇ组有明显的镇痛作用，３．０ｇ／ｋｇ组对三联茵苗致热大鼠有明显的解热作用，另外，该工对金葡菌和肺炎双球菌亦有抑制作用。     

羌银解热合剂抗炎镇痛解热作用研究

目的：研究羌银解热合剂的抗炎镇痛、解热作用。方法：以羌银解热合剂高剂量组（25．2g／ks）、中剂量组（12．6g／ks）、低剂量组（6．3g／ks）灌胃，分别观察对酵母混悬液致大鼠发热的解热作用，对鸡蛋清致大鼠足跖肿胀和二甲苯致小鼠耳肿胀的抗炎作用，对小鼠热板法和冰醋酸致小鼠扭体的镇痛作用。结果：羌银解热合剂高剂量组能显著抑制酵母混悬液致大鼠发热、鸡蛋清致大鼠足跖肿胀、二甲苯致小鼠耳肿胀，显著提高小鼠热板法的痛阈值，显著减少冰醋酸致小鼠扭体次数。结论：羌银解热合剂具有较好的解热、抗炎、镇痛作用。     

白芷提取物欧前胡素镇痛作用实验研究

目的:考察中药白芷提取物欧前胡素的镇痛作用。方法:采用小鼠扭体法、热板法和大鼠足跖定压刺激法考察欧前胡素的镇痛作用。结果:镇痛实验显示,欧前胡素有延长扭体反应潜伏期、减少扭体次数的作用;对热板法痛阈值无显著影响;在提高致炎足痛阈值的同时,对正常足痛阈值无影响。结论:首次证实欧前胡素有镇痛作用,其镇痛部位可能在外周。     

乌鸡调经丸补血镇痛实验研究

目的：观察乌鸡调经丸的补血、镇痛作用。方法：在正常小鼠及失血性血虚证小鼠模型上观察其用药后ＲＢＣ、Ｈｂ;在小鼠热板和扭体反应模型上观察其用药后不同时间痛阗值、扭体反应开始时间（潜伏期）和扭体数的变化。结果：乌鸡调经丸０．７４、１．４８、２．９６ｇ生药／ｋｇ,ｉｇ分别显著增加血虚证小鼠ＲＢＣ和Ｈｂ,显著提高小鼠痛阈值,显著延长致痛潜伏期并明显减少扭体反应数。结论：乌鸡调经丸具有明显补血、镇痛作用。     

妇舒镇痛与抗炎作用的实验研究

目的：探讨妇舒的抗炎、镇痛作用。方法：采用小鼠热板法、醋酸致扭体法进行镇痛试验;用角叉菜胶致大鼠足跖肿胀法、二甲苯所致小鼠耳廓肿胀法及对小鼠毛细血管通透性测定法观察抗炎作用。结果：妇舒能使小鼠热板致痛反应的痛阈值明显延长,醋酸所致扭体次数明显减少,能显著抑制角叉菜胶所致大鼠足跖、二甲苯所致小鼠耳廓肿胀,并明显抑制毛细血管通透性。结论：妇舒具有抗炎、镇痛作用。     

跌打七厘片的药效学研究

目的观察跌打七厘片的药效学作用。方法应用二甲苯致小鼠耳肿胀法、蛋清致大鼠足跖炎症法、小鼠热板法、醋酸致小鼠扭体反应法、凝血时间测定、创伤局部（断尾）止血等实验方法对跌打七厘片进行药效学观测。结果跌打七厘片对二甲苯致小鼠耳廓炎症有显著的抑制作用，对蛋清性大鼠足跖炎症肿胀有显著的抑制作用，对热刺激致痛有明显的镇痛作用，对醋酸扭体反应有明显的镇痛作用，对凝血时间无明显影响，对创面局部（断尾）出血有加快止血的趋势。结论跌打七厘片具有良好的抗炎、镇痛、止血作用。     

丹芷胶囊抗炎 镇痛作用的实验研究

目的：评价丹芷胶囊的抗炎、镇痛作用。方法：用二甲苯致小鼠耳廓肿胀试验、角叉菜胶致大鼠足跖肿胀试验，考察丹芷胶囊的抗炎作用；用小鼠醋酸扭体法和热板法，考察丹芷胶囊的镇痛作用。结果：丹芷胶囊能明显抑制二甲苯致小鼠耳廓肿胀和角又菜胶致大鼠足跖肿胀；对醋酸致小鼠扭体反应有明显的抑制作用，提高小鼠热痛闲值。结论：丹芷胶囊有明显的抗炎、镇痛作用。     

通络止痛软膏抗炎、镇痛作用的实验研究

目的评价通络止痛软膏的抗炎、镇痛作用。方法用二甲苯致小鼠耳廓肿胀试验、角叉菜胶致大鼠足跖肿胀试验，考察通络止痛软膏的抗炎作用；用小鼠醋酸扭体法和热板法，考察通络止痛软膏的镇痛作用。结果通络止痛软膏能明显抑制二甲苯致小鼠耳廓肿胀和角叉菜胶致大鼠足跖肿胀；对醋酸致小鼠扭体反应有明显的抑制作用，可提高小鼠热痛阈值。结论通络止痛软膏有明显的抗炎、镇痛作用。     

丹芷胶囊抗炎镇痛作用的实验研究

目的:评价丹芷胶囊的抗炎、镇痛作用。方法:用二甲苯致小鼠耳廓肿胀试验、角叉菜胶致大鼠足跖肿胀试验,考察丹芷胶囊的抗炎作用;用小鼠醋酸扭体法和热板法,考察丹芷胶囊的镇痛作用。结果:丹芷胶囊能明显抑制二甲苯致小鼠耳廓肿胀和角叉菜胶致大鼠足跖肿胀;对醋酸致小鼠扭体反应有明显的抑制作用,提高小鼠热痛阈值。结论:丹芷胶囊有明显的抗炎、镇痛作用。     

The hypotensive effects of green bean (Phaseolus aureus), common rue (Ruta graveolens) and kelp (Laminaria japonica) in rats

The nature and effect of the changes in mean arterial pressure (MAP) of albino normotensive rats through i.v. injection of aqueous extracts of green bean, common rue and kelp were studied with emphasis on possible interactions among these extracts. All extracts were hypotensive, contained bioactive proteinaceous substances and stimulated urine flow. A combination of two or three plant extracts showed subtractive or additive effects, suggesting important bearing on their use therapeutically. © 1997 John Wiley & Sons, Ltd.     

Phytochemistry and Medicinal Properties of Teucrium polium L. (Lamiaceae)

Teucrium polium L. (family Lamiaceae) is a wild‐growing flowering plant, found abundantly in South‐Western Asia, Europe and North Africa. Traditionally, T. polium has been used for different pathological conditions such as gastrointestinal disorders, inflammations, diabetes and rheumatism. In traditional Iranian medicine (TIM), the tea of T. polium is used for treating many diseases such as abdominal pain, indigestion, common cold and type 2 diabetes. Based on this background, many studies have been followed for scientific confirmation of the above‐mentioned properties. In this review, 100 articles published from 1970 to 2011 in the area of phytochemistry, pharmacology and toxicology of extracts and compounds isolated from T. polium have been evaluated. During the past 40 years, different classes of compounds have been isolated from various parts of T. polium of which the main groups are terpenoids and flavonoids. It has been found that these compounds possess a broad spectrum of pharmacological effects including antioxidant, anticancer, antiinflammatory, hypoglycemic, hepatoprotective, hypolipidemic, antibacterial and antifungal. The results of data analyses on the chemical, pharmacological and toxicological characteristics of T. polium support the view that this plant has beneficial therapeutic properties. However, further studies to identify the active components and further verify their relevant pharmacological activities are warranted. Copyright © 2012 John Wiley & Sons, Ltd.     

黑芨（落新妇根）的抗癌活性研究

体内抗肿瘤实验结果表明，落新妇根具有抑制小鼠Ｓ_１８０实体瘤生长及延长ＥＡＣ腹水癌小鼠的生存期，并在较低浓度时有促进体外淋巴细胞转化的作用，揭示该药在体内有一定的抗肿瘤作用。     

耳压治疗胆石症126例临床观察

胆石症属临床常见病,用耳压疗法治疗216例胆石症,获满意疗效.取主穴胰胆、肝、脾、三焦、内分泌、肾上腺、神门,配穴:口、食道、十二指肠、小肠、交感、眼、上背、中背、下背、耳迷根.用橡皮膏粘王不留籽粘于穴位,日压7次;同时食用高脂食物配合治疗.痊愈68例(54%),显效30例(23.6%),有效23例(18%),无效5例(4%).     

麦门冬饮子加味治疗慢性呼吸衰竭失代偿期89例

慢性呼吸衰竭失代偿期患者病情重笃，治疗困难，死亡率高。本文介绍用麦门冬饮子加味配合西医治疗89例，与同期单纯西医治疗42例比较，经临床症状、体征、动脉血气分析、心肌酶谱、心电图等观察，改善率均好于对照组。综合评定疗效显效率47．19％，明显好于对照组(23．8％）。说明麦门冬饮子加味配合抢救慢性呼衰失代偿期患者有较为可靠的疗效。     

郁金饮片炮制历史沿革及现代研究

对郁金的植物资源、饮片炮制沿革、化学成分及药理活性的研究进行了分析和总结，并讨论郁金与姜黄、莪术的品种关系，为郁金饮片炮制规范化及建立质量标准提供借鉴。     

Effects of ethanol and water extracts of propolis (bee glue) on acute inflammatory animal models

The anti-inflammatory effects of ethanol (EEP) and water (WSD) extracts in ICR mice and Wistar rats were analyzed. Both WSD and EEP exhibited significant anti-inflammatory effects in animal models with respect to thoracic capillary vessel leakage in mice, carrageenan-induced oedema, carrageenan-induced pleurisy, acute lung damage in rats. The mechanisms for the anti-inflammatory effects probably involve decreasing prostaglandin-E₂ (PGE₂) and nitric oxide (NO) levels. In rats with Freund's complete adjuvant (FCA) induced arthritis, propolis extracts significantly inhibited the increase of interleukin-6 (IL-6) in inflamed tissues, but had no significant effect on levels of interleukin-2 (IL-2) and interferon-γ (IFN-γ). The results are consistent with the interpretation that EEP and WSD may exert these effects by inhibiting the activation and differentiation of mononuclear macrophages.     

明矾枯痔液治疗痔疮1010例临床观察

为了提高痔疮的临床疗效,自制明矾枯痔液治疗痔疮患1010例.方由明矾12g(或6g)、石炭酸2g、枸橼酸钠2.5g、奴夫卡因0.5g,加蒸溜水l00ml.对I、Ⅱ、Ⅲ期患者分别注入6%、12%明矶枯痔液0.5~1 ml.以痔核脱落,创面修复、疼痛消失、肛门功能正常为观察指标.结果:痊愈960例,好转38例,无效12例,总有效率为98.8%.     

针刺治疗小儿支气管哮喘20例临床观察

运用针刺治疗20例苏联小儿支气管哮喘患儿,取定喘、膻中、肺俞为主穴,以宣肺理气、化痰降逆平喘,且随症变化。显效16例,占80％;有效3例,占15％;无效1例,占5％;总有效率95％。疗程5d者15例,10d者4例,15d者1例。