Central illustration. Prevalence of familial hypercholesterolaemia (FH) among young adults with myocardial infarction (MI) (n = 457) and in the general control population (CARVAR 92 cohort) (n = 9900), and cardiovascular risk factors associated with premature acute MI. 相似文献
Central illustration. Six-month mortality according to category of coronary artery calcium (CAC). The mortality rate increased with the magnitude of calcifications according to a visual scoring of CAC on chest computed tomography. CAC was associated with 6-month mortality, independent of conventional cardiovascular risk-factors, in patients hospitalized for coronavirus disease 2019 without known atheromatous disease. CI: confidence interval; HR: hazard ratio. 相似文献
Central illustration. Proportion of pulmonary hypertension (PH) in infantile scimitar syndrome, and distribution of causes according to the number of associated causes. L-R shunt: left-to-right shunt in congenital heart defect; PPHN: persistent pulmonary hypertension of the newborn. 相似文献
Central illustration. Endothelial progenitor cell (EPC) extraction, culture and characterisation, and adhesion, proliferation and haemocompatibility testing on three devices. ASD: atrial septal defect; NS: not significant; PC: positive control. 相似文献
Background and aimsEpicardial adipose tissue (EAT) is the visceral fat between the myocardium and the visceral pericardium. Dysfunctional EAT can cause cardiovascular diseases. The aim of this study was to investigate the association between EAT and left ventricular function in type 2 diabetes mellitus (T2DM) patients by two-dimensional speckle tracking echocardiography (2D-STE).MethodsWe prospectively enrolled 116 T2DM patients who were divided into two groups according to their left ventricular global longitudinal strain (GLS): 53 with GLS <18% and 63 with GLS ≥18%. The thickness of EAT was measured as the echo-free space between the free wall of the right ventricle and the visceral layer of pericardium at end-systole. LV systolic function was evaluated by GLS measured by 2D-STE. LV diastolic function was defined as the ratio of the early diastolic transmitral flow velocity (E) to average mitral annular velocity ().ResultsCompared with patients with GLS ≥18% group, the age, body mass index (BMI), waist circumference (WC), systolic blood pressure (SBP), diastolic blood pressure (DBP), low-density lipoprotein cholesterol (LDL-C), glycosylated hemoglobinA1c (HbA1c), E/, and thickness of EAT were higher in patients with GLS <18% group (all P < 0.05). Multivariate linear regression analysis revealed that the thickness of EAT was independently associated with left ventricular GLS and E/.ConclusionsThickened EAT is associated with impaired left ventricular function in T2DM patients. To investigate the association between EAT and left ventricular function can help us gain a deeper understanding of the pathogenesis of impaired cardiac function in T2DM patients. 相似文献
