左肾旁前间隙入路在保留脾动静脉腹腔镜胰体尾切除术中的应用

目的 探讨保留脾动静脉腹腔镜胰体尾切除术安全快捷的手术入路.方法 回顾总结我院12 例保留脾动静脉腹腔镜胰体尾切除术的手术过程及结果,分析左肾前间隙入路在保留脾动静脉腹腔镜胰体尾切除术中的应用.结果 12 例手术顺利完成,平均手术时间(55±18)min,术中出血量(80±46)mL,术后平均住院时间7.6 d,术后未发生胰漏等并发症.结论 左肾前间隙入路是脾动静脉腹腔镜胰体尾切除术中安全快捷的手术入路.     

Kimura法保留脾脏的腹腔镜胰体尾切除术

目的探讨Kimura法保留脾脏的腹腔镜胰体尾切除术的安全性和可行性。方法回顾性分析2016年8月~2019年3月Kimura法保留脾脏的腹腔镜胰体尾切除术11例资料。均为胰体尾部单发病灶,直径2.0~5.0 cm,平均3.5 cm。结果11例手术均顺利完成,无中转开腹。手术时间125~185 min,平均155 min;出血量35~100 ml,平均65 ml,术中均未输注血制品;围手术期无死亡,无腹腔出血、B级或C级胰漏、脾梗死等严重并发症发生。术后住院6~12 d,平均7.8 d。11例随访1~32个月,中位数16个月,均未见肿瘤复发、转移及脾梗死。结论Kimura法保留脾脏的腹腔镜胰体尾切除术安全、可行。     

保留脾血管的腹腔镜胰体尾切除术

目的:探讨保留脾脏血管腹腔镜胰体尾切除术的可行性与安全性。方法:回顾分析2011年3月至2014年7月为38例患者行保留脾血管腹腔镜胰体尾部肿瘤手术的临床资料。结果:手术时间116~295 min,平均(170.5±50.2)min;术中失血量15~565 ml,平均(112.3±33.6)ml;均未输血。病理检查结果示胰腺导管腺癌11例,浆液性囊腺瘤6例,黏液性囊腺瘤9例,黏液性囊腺瘤局部癌变2例,胰岛素瘤4例,实性假乳头状肿瘤6例。术后3例发生胰漏,经保守治疗好转。余者术后均恢复顺利,无并发症发生,术后平均住院(7.36±2.13)d。结论:腹腔镜保留脾脏血管胰体尾切除术是有效治疗远端胰腺肿瘤的新术式,具有微创优势,安全、可行。     

脾血管优先技术在腹腔镜保留脾脏胰体尾切除术中的应用

[摘 要] 目的 探讨脾血管优先技术在腹腔镜保留脾脏胰体尾切除术中的应用。方法 回顾性分析2011年6月至2017年12月浙江省人民医院和浙江省长兴县人民医院采用腹腔镜保留脾脏胰体尾切除术治疗的58例胰体尾良性或交界性占位病变患者的临床资料。结果 中转开腹2例;余56例均顺利完成手术,其中保留脾动、静脉的保脾胰体尾切除术（Kimura法）53例,离断脾血管、保留胃短血管的保脾胰体尾切除术（Warshaw法）3例。手术时间65～220（160±30）min,出血量30～500（100±25）mL,术后住院时间5～21（8±5）d。术后并发生化瘘15例,B级胰瘘2例,C级胰瘘1例,腹腔出血1例,腹腔脓肿2例,肺部感染2例。术后病理诊断为胰腺内分泌肿瘤8例,胰腺导管内乳头状黏液瘤10例,胰腺实性假乳头状瘤12例,黏液性囊腺瘤10例,浆液性囊腺瘤13例,慢性胰腺炎肿块5例。结论 脾血管优先技术具有简便、安全的特点,有助于主动选择术式和规划手术路径,提高腹腔镜胰尾切除术的安全性和保脾成功率。     

腹腔镜胰体尾切除30例报告

目的探讨腹腔镜胰体尾切除的安全性和可行性。方法 2013年1月~2016年6月对30例胰体尾占位性病变施行腹腔镜下胰体尾切除。术中定位肿物及胰腺切线,充分游离胰颈并应用Endo-GIA切断胰腺,根据肿物性质及肿物与脾血管关系决定是否保留脾脏。结果 4例因脾血管出血难以控制中转开腹。行腹腔镜保留脾脏胰体尾切除15例,其中保留脾血管的保脾胰体尾切除(Kimura法)10例,手术时间210~260 min,(232±14)min,术中出血量120~200 ml,(165±21)ml;不保留脾血管的保脾胰体尾切除(Warshaw法)5例,手术时间110~170 min,中位手术时间135 min,术中出血量50~130ml,中位出血量80 ml。胰体尾及脾切除11例,手术时间95~190 min,(137±31)min,术中出血量30~150 ml,(83±41)ml。术后住院时间7~22 d,(12.2±2.4)d。术后病理:黏液性囊腺瘤9例,实性假乳头状瘤7例,神经内分泌肿瘤6例,浆液性囊腺瘤3例,胰腺囊肿3例,导管内乳头状黏液瘤1例,异位脾脏1例。术后胰漏发生率36.7%(11/30),部分脾梗死1例。21例随访中位时间15个月(6~36个月),未见肿瘤复发。结论对于胰体尾良性、交界性或低度恶性肿瘤,选择腹腔镜下胰体尾切除安全可行,创伤小,恢复快。     

腹腔镜保留脾脏胰体尾切除术的关键技术

腹腔镜保留脾脏胰体尾切除术适用于胰体尾部良性或低度恶性病变,避免了脾切除术后近、远期并发症,手术方式包括保留脾动静脉的Kimura手术和切除脾动静脉主干、保留胃网膜左血管等侧枝循环的Warshaw手术。腹腔镜下Kimura手术视野清晰,安全可行,术后并发症发生率低,应为保脾胰体尾切除手术的首选。术前检查或术中探查可疑为浸润性恶性病变或病灶与脾血管、脾门关系密切者,应果断放弃保脾术式,改行胰体尾联合脾切除术。     

保留脾脏的胰体尾部良性肿瘤切除

目的探讨保留脾脏胰体尾切除的可行性和安全性以及并发症预防。方法回顾性分析总结2009年1月至2011年12月行保留脾脏胰体尾切除术5例资料,其中保留脾脏血管的开腹保脾胰体尾切除3例,切断(或切除)脾脏血管的保脾胰体尾切除术1例,腔镜下保脾胰体尾部切除术1例。结果本组无手术死亡,术后均未发生胰瘘、脾梗死、脾脓肿及脾出血等。随访3～6月,无并发症发生。结论胰体尾部良性肿瘤,应首选保留脾脏的胰体尾切除方法,手术安全,效果好,且避免了脾脏的不必要切除。     

保留脾脏胰体尾切除术的临床探讨

目的探讨保留脾脏胰体尾切除术的可行性和安全性。方法总结2006年2月—2010年8月1 6例胰体尾部良性和交界性病变实行了保留脾脏的胰体尾切除术的临床资料,其中15例为保留脾脏血管胰体尾切除,1例为切断脾血管保留脾脏胰体尾切除。结果术后发生胰瘘9例,切口感染1例,腹腔出血3例(其中1例为胰瘘后发生出血),胸腔积液2例。9例胰瘘者,8例经非手术治疗,3~7周痊愈,1例并发出血后行数字减影脾动脉栓塞止血,第17周痊愈。另2例腹腔出血者,1例经非手术治疗治愈,1例二次手术,见脾静脉分支出血,结扎止血。全组无死亡病例。结论胰体尾部良性和交界性肿瘤,可首先选择保留脾脏的胰体尾切除术,手术安全,疗效好。     

保留脾脏的胰体尾部良性病变切除术8例报告

1995年 2月至 2 0 0 2年 12月 ,我院对胰体尾部良性病变施行切除脾动静脉保留脾脏的胰体尾切除术 8例。8例病人中 ,男 5例 ,女 3例。年龄 18～ 6 2岁 ,平均 4 0岁。术前CT检查均提示胰体尾良性病变 ,术中、术后病理证实其中胰腺囊腺瘤 2例 ,非功能性胰岛细胞瘤 1例 ,胰腺假性囊肿 3例 ,胰体尾外伤 2例。术前B超及CT检查脾脏正常 ,均行切除脾动静脉保留脾脏的胰体尾切除术。手术方法 :充分切开胃结肠韧带进入小网膜腔 ,置入S拉钩向上牵开胃壁 ,使胰体尾和脾门完全显露。控查肿瘤 ,并取少许组织送快速病理检查 ,如为良性肿瘤 ,则准备行保留…     

腹腔镜下保留脾脏的胰体尾切除术4例

目的：探讨在腹腔镜下,对胰体尾部肿瘤患者进行保留脾脏的胰体尾切除术的可行性与安全性。方法：我院2008年2月—2010年4月对4例胰体尾良性病变施行腹腔镜下保留脾脏的胰体尾切除术。结果：4例手术均顺利完成,平均手术时间为235（115～305）min,术中平均出血量为200（100～450）mL,术后平均住院时间为12.8（10～21）d,术后有1例患者产生胰瘘,延迟拔管,治愈后出院。术后病理诊断为胰体尾浆液性囊腺瘤2例,黏液性囊腺瘤1例,胰岛细胞瘤1例。结论：对胰体尾部的良性病变行腹腔镜下保留脾脏的胰体尾切除术是微创并安全的,具有恢复快、并发症少等优点。     

经脐单一部位腹腔镜胰体尾切除术的初步体会

目的探讨经脐单一部位腹腔镜胰体尾切除术的可行性。方法 2009年6月～2011年10月对8例胰体尾部良性病变施行经脐单一部位腹腔镜胰体尾切除手术,其中保留脾脏3例,联合脾切除5例。超声刀游离周围韧带及远端胰腺,切割闭合器将胰体尾及脾血管切断,标本经脐取出。结果 7例经脐单一部位腹腔镜胰体尾切除术成功,1例因胰尾囊肿与周围粘连严重中转为多孔手术。手术时间130～240 min,(155±38)min;出血量50～250 ml,(101.3±71.6)ml;住院时间6～9 d,(7.4±1.1)d。所有患者均无术后出血、静脉血栓、发热感染等并发症。1例持续性胰漏,开腹手术修补。术后脐部切口愈合良好,美容效果明显。8例术后随访3～28个月,(14.3±8.6)月,均恢复正常工作及生活,预后良好。结论对于有经验的腹腔镜外科医生,经脐单一部位腹腔镜胰体尾切除术是可行的,并具有极佳的美容效果。     

保留脾脏的胰体尾切除术的临床应用

目的 总结保留脾血管的保留脾脏胰体尾切除术的临床应用经验.方法 回顾性分析中山大学附属第一医院胃肠胰腺外科和广东省人民医院普通外科2002年5月至2009年4月间施行的26例胰体尾切除手术,其中选择保留脾脏组13例,切除脾脏组13例.比较两组的手术时间,术中出血量,术后感染与非感染并发症,术后血小板计数及术后住院时间等情况.结果 保留脾脏组和切除脾脏组在手术时间[(172±47)min比(157±52)min,P＞0.05],术中出血量[(183±68)ml比(160±51)ml,P＞0.05],术后并发症和术后住院时间等差异无统计学意义[(10.1±2.2)d比(12.1±4.6)d,P＞0.05];而术后血小板计数差异有统计学意义[(37.3±12.8)×109/L比(54.7±13.2)×109/L,P＜0.05].结论 保留脾脏的胰体尾切除手术治疗胰腺良性或低度恶性肿瘤是可行、安全的.     

Laparoscopic distal pancreatectomy with preservation of the spleen

We describe a case of chronic pancreatitis treated by laparoscopic distal pancreatectomy with conservation of the spleen involving the resection of the splenic vessels. A proximal ligation of the splenic artery and vein was performed, followed by transection of the body of the pancreas. Retroperitoneum was dissected to the left by mobilizing the stump of the transected pancreas. The entire distal pancreas was freed posteriorly. The distal splenic artery and vein were ligated and divided individually adjacent to the tail of the pancreas at the hilum of the spleen. The points of this operation were to ligate the splenic artery and vein at both sides of the resected pancreas and to save the spleen with the blood supply continuing through the short gastric vessels and the splenocolic ligament. This operation with splenic preservation is more suitable for a patient who is a candidate for laparoscopic distal pancreatectomy, which will minimize the operation time, preserve the useful immunologic role of the spleen, and obtain the intact resected specimen. Furthermore, this procedure is useful in chronic pancreatitis patients because it avoids the difficult dissection of the posterior pancreas off of the splenic vessels.     

Novel approach to laparoscopic resection of tumours of the distal pancreas

Background: Laparoscopic resection for small lesions of the pancreas has recently gained popularity. We report our initial experience with a new approach to laparoscopic spleen‐preserving distal pancreatectomy so that the maximum amount of normal pancreas can be preserved while ensuring adequate resection margins and preservation of the spleen and splenic vessels. Methods: Three patients underwent laparoscopic distal pancreatectomy with spleen and splenic vessel preservation over a 2‐month period. Surgical techniques and patient outcomes were examined. Results: All three patients were females, with ages ranging from 31 to 47 years. Two patients underwent resection using the conventional medial‐to‐lateral dissection as the lesion was close to the body or proximal tail of the pancreas. The third patient had a lesion in the distal tail of the pancreas and surgery was carried out in a lateral‐to‐medial manner. This new approach minimized excessive sacrifice of normal pancreatic tissue for such distally located lesions. The splenic artery and vein were preserved in all cases and there was no significant difference in clinical outcome, operative time or intraoperative blood loss. Conclusion: Laparoscopic distal pancreatectomy with preservation of the spleen and splenic vessels is a feasible surgical technique with acceptable outcome. We have shown that a tailored approach to dissection and pancreatic transection based on the location of the lesion allows the maximum amount of normal pancreatic tissue to be preserved without additional morbidity. Although the conventional ‘medial‐to‐lateral’ approach is recommended for more proximal tumours of the pancreas, distal lesions can be safely addressed using the ‘lateral‐to‐medial’ approach.     

The feasibility of spleen-preserving pancreatectomy for end-stage chronic pancreatitis

BACKGROUND: It is considered difficult to preserve the spleen at the time of distal or total pancreas resection for chronic pancreatitis (CP). The aim of this study was to assess the feasibility of preserving the spleen in patients requiring total or completion pancreatectomy for CP. METHODS: All patients having total or completion pancreatectomy for CP were evaluated postoperatively in terms of morbidity, mortality, and pain relief. To assess splenic vascularity, all patients underwent abdominal ultrasound and power doppler imaging to assess splenic perfusion and the patency of the remaining splenic vessels. RESULTS: Of 35 patients having total pancreatectomy, the spleen was preserved in 30 patients (19 women, 11 men; median age 40 years). The etiology of CP was mainly idiopathic (n = 14) or alcohol related (n = 12). All patients presented with chronic abdominal pain (median 5 years) requiring opiate-derived analgesia for pain relief. Fifteen patients (50%) had undergone previous therapeutic intervention for pain relief. The spleen was preserved with either an intact splenic artery and vein in 19 patients and or the short gastric vessels (n = 11). The mean duration of the procedure was 7 hours (range 5 to 11) and mean blood loss was 1,090 mL. The 30-day mortality was 3.8% (n = 1). Five patients had splenic complications (17%). These included splenectomy (n = 2), intrasplenic collection (n = 2), and a wedge splenic infarct (n = 1). Two of these complications were related to intrasplenic islet autotransplants. Follow-up with abdominal ultrasound and power doppler scanning showed no other abnormalities; blood flow was demonstrable in all patients with intact splenic arteries and vein (n = 19). The mean hospital stay was 25 days. Of the 24 patients who were beyond 6 months' follow-up, 82% (n = 20) have complete relief of pain, and 4 still require opiate analgesia. CONCLUSIONS: Spleen-preserving pancreatectomy is a feasible procedure for chronic pancreatitis, providing complete pain relief in 80% of patients. When the splenic artery and vein cannot be preserved, there is a minimal risk of splenic complications that may require further treatment; but for the majority of patients, splenectomy is avoided.     

腹腔镜胰腺远端切除术26例

目的探讨腹腔镜胰腺远端切除术的安全性、可行性。方法2005年9月～2008年6月,对26例胰腺体尾部肿物行腹腔镜胰腺远端切除术。术前25例诊断为胰腺体尾部良性肿物,1例不除外恶性,肿物中位直径5cm（1.2～10cm）。结果所有手术均在全腹腔镜下完成。15例行保留脾脏的胰体尾切除（10例保留脾动静脉,5例未保留脾动静脉）,10例行胰体尾加脾切除,1例既往行胰体尾及脾切除者行胰体部切除。手术中位时间268.5min（129～400min）,中位出血量100ml（50～800ml）,术后中位住院时间9d（6～21d）。无胰漏或脾梗死发生,2例包裹性积液,均保守治疗治愈,1例引流管口感染。26例中位随访时间15.5月（1～35个月）,均无复发。结论胰腺体尾部良性肿物行腹腔镜胰腺远端切除术安全、可行。     

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??Vascular disposal in laparoscopic spleen-preserving distal pancreatectomy??An analysis of 22 patients HUANG He-guang, CHEN Yan-chang, LU Feng-chun, et al. Department of General Surgery, Fujian Medical University Union Hospital, Fuzhou 350001, China
Corresponding author: HUANG He-guang, E-mail: hhuang2@aliyun.com
Abstract Objective To investigate experience with the techniques of vascular disposal in laparoscopic spleen-preserving distal pancreatectomy. Methods The clinical data of 22 patients with benign or borderline pancreas pancreatic tumors performed a spleen-preserving distal pancreatectomy from February 2010 to December 2013 in Fujian Medical University Union Hospital were analyzed retrospectively. Results Among 22 patients, splenic artery and vein were conserved in 16 patients, while neither in 2 patients. Splenic artery was ligated with conservation of splenic vein in 2 patients. And splenic vein was ligated with conservation of splenic artery in 2 patients. All distal pancreatectomies with spleen preservation were completed laparoscopically. And all patients remained a good blood supply to spleen at a follow-up of 3 months to 4 years. Conclusion Depending on the relationship between tumors and vessels, the spleen can be safely preserved laparoscopically using different vascular disposal methods in benign or borderline pancreatic tumors.     

腹腔镜脾脏部分切除术（附6例报告）

目的探讨腹腔镜脾脏部分切除术的可行性和安全性。方法2008年4月-2012年11月,对6例CT或MRI检查明确诊断为脾脏囊性病变施行腹腔镜脾脏部分切除术,肿物最大径5．3-17．2cm,平均8．9cm,位于上极1例,中上极1例,下极4例。经脐孔穿刺建立气腹,于脾门处游离并切断脾脏上极或下极血管,沿缺血线行规则性脾部分切除术。结果6例均在腹腔镜下完成手术,手术时间175～325rain,平均230．8min;术中出血量50～700ml,中位出血量150ml。脾窝引流管放置时间3—6d,平均4d。未发生胰腺损伤、胰漏、出血、脾窝感染等并发症。术后住院3—6d,平均4．8d。6例随访2—57个月,中位时间5．5月,无囊肿复发。结论位于上极或下极的脾脏良性肿物可以在腹腔镜下施行部分脾切除术,手术安全且创伤小。     

保留脾脏及供应血管胰体尾切除治疗胰腺断裂伤18例报道

目的 探讨保留脾脏胰体尾切除治疗胰腺体尾部断裂伤的临床可行性和效果.方法 对扬州大学临床医学院2008年3月-2012年11月实施保留脾脏胰体尾切除治疗胰腺断裂伤18例患者的临床资料进行回顾性分析评价.结果 18例患者均能顺利施行保留脾脏胰体尾切除.手术时间152 ～188 min,平均172 min;术中出血量155 ～356 mL,平均191 mL;住院时间为13～19 d,平均15 d.无术后大出血、胰漏、腹腔感染等严重术后并发症.结论 保留脾脏胰体尾切除治疗胰腺体尾部断裂伤减少了“无辜性脾切除”,是一种保全脏器功能效果较好、安全可行的手术方式.     

Kimura法与Warshaw法在腹腔镜保留脾脏的胰体尾切除术中的临床对照研究

[摘 要] 目的 探讨Kimura法与Warshaw法两种腹腔镜保留脾脏的胰体尾切除术方法的安全性。方法回顾性分析咸阳市第一人民医院2014年9月至2017年9月共13例行腹腔镜保留脾脏的胰腺体尾良性病变切除术患者资料,其中Kimura组8例,Warshaw组5例,对两种手术方式术中出血量、手术时间、术后排气时间及术后住院时间等方面进行对比研究。结果 两组均手术成功,无中转开腹,无中转腹腔镜胰体尾切除+脾脏切除术病例。两组术中出血量[（62.5±45.7）mL vs （84.3±52.2）mL],手术时间[（274.4±32.1）min vs （283.2±24.8）min],术后排气时间[（1.3±0.5）d vs （1.8±0.9）d],以及术后住院时间[（9.3±4.5）d vs （10.7±6.9）d]差异均无统计学意义（P＞0.05）。Warshaw组1例术后CT提示无症状的部分脾梗死发生,1例发生胃静脉曲张。两组患者无其他近远期并发症及再次手术发生,无病变复发,无胃静脉曲张破裂出血发生。结论两种手术方式均是安全和有效的,与Kimura法相比,Warshaw法无症状脾梗死、胃底静脉曲张发生率较高。但在肿瘤或胰腺病变与脾血管分离困难时,选择Warshaw法更为合适。