芒针秩边透水道治疗脊髓损伤后尿潴留87例

目的观察芒针"秩边透水道"对脊髓损伤引起尿潴留的影响。方法将87例脊髓损伤患者随机分为芒针透穴组和常规针刺组,芒针透穴组采用芒针秩边透水道方法,要求针感向尿道及肛门周围扩散,常规针刺组采用常规针刺方法。结果芒针透穴组总有效率88.64%,常规针刺组69.77%,与常规针刺组比较P0.05,具有显著性差异。结论芒针"秩边透水道"对脊髓损伤引起的尿潴留疗效显著,优于一般针刺方法。     

杨兆钢芒针针刺方向浅析

介绍天津杨兆钢主桥医师芒针针刺临床经验，杨氏认为通过针刺方向的变化，可充分发挥芒针选穴精少、刺法灵巧，以及芒针所特有透穴针法的特点。对同一腧穴，采取不同的针刺方向、拓展了穴位的临床应用范围。     

中脘穴芒针刺法临床应用举隅

中脘穴在临床应用极为广泛,作者有幸师从于全国芒针专家杨兆钢教授,获益良多。根据杨师所授,结合临床实践体会,就芒针针刺中脘穴治疗常见疾病进行总结,旨在探求以中脘为主穴,采用芒针针刺,治疗常见疾病的规律。     

近10年针刺治疗中风后吞咽障碍研究概况

中风后吞咽障碍是中风后常见并发症,其发病严重影响患者生存和生活质量.作者查阅近10年针刺治疗中风后吞咽障碍的文献,总结了运用不同针刺方法治疗该症的研究概况,包括舌针、眼针、电针、项针、常规针刺、水针、火针、皮内针、头针、芒针、刺络放血、合谷刺、腹针等针刺方法,为临床针刺治疗本症提供依据.     

芒针针刺治疗卵巢早衰临床研究

目的:观察芒针针刺治疗卵巢早衰的临床疗效。方法:将60例患者按照随机数字表法分为对照组和治疗组,每组各30例。对照组给予克龄蒙片治疗,治疗组在对照组的基础上给予芒针针刺治疗。结果:对照组有效率为70.00%,治疗组有效率为93.33%,两组有效率比较,差异有统计学差异(P<0.05);两组治疗后雌激素水平及卵泡雌激素水平与治疗前比较,差异有统计学意义(P<0.05)。结论:芒针针刺治疗卵巢早衰疗效显著。     

芒针透刺督脉组穴联合平衡训练治疗卒中后平衡障碍

目的:观察芒针透刺督脉组穴联合平衡训练治疗脑卒中偏瘫患者平衡障碍的临床疗效。方法:90例卒中后平衡障碍患者以就诊顺序随机分为芒针通督组、普通针刺组和平衡训练组各30例。平衡训练组给予单纯平衡训练,普通针刺组在平衡训练基础上给予毫针针刺治疗,芒针通督组在平衡训练基础上给予芒针通督组穴治疗,3组患者均治疗3个疗程。比较3组患者治疗前后步行功能(Holden步行能力分级)、平衡功能(Berg平衡量表,Fugl-Meyer量表)。结果:治疗后,3组患者平衡功能、步行运动能力均优于治疗前,差异均有统计学意义(P0.05);且芒针通督组平衡功能、步行运动能力均优于其他两组,差异均有统计学意义(P0.05)。芒针通督组有效率(96.6%)显著高于普通针刺组(83.3%)、平衡训练组(73.3%),差异均有统计学意义(P0.05)。结论:芒针透刺督脉组穴联合平衡训练治疗卒中后平衡障碍患者疗效显著,可显著提高患者平衡功能、步行运动能力。     

芒针治疗慢性前列腺炎38例临床观察

观察以芒针深透秩边穴为主治疗慢性前列腺炎与常规腧穴方法的疗效差别,发芒针组及常规针刺方法对照组,治疗一疗程后,结果芒针组有效率高于对照组,芒针深透秩边穴对慢性前列腺炎的疗效优于常规方法。     

“腿痛穴”芒刺配合阳陵泉温针灸治疗腰椎间盘突出症临床观察

目的:探寻治疗腰椎间盘突出症根性痛的有效方法。方法:将216例患者随机分为芒针治疗组、常规针刺对照组。分别采用芒针合阳陵泉温针灸、常规针刺治疗,观察镇痛起效时间及综合疗效评价。结果:治疗组镇痛起效时间短于对照组,综合疗效评价优于对照组,差异有显著性意义。结论:芒针合阳陵泉温针灸对腰椎间盘突出症根性痛具有较好的镇痛效果。     

“腿痛穴”芒剌配合阳陵泉温针灸治疗腰椎间盘突出症临床观察

目的：探寻治疗腰椎间盘突出症根性痛的有效方法。方法：将216例患者随机分为芒针治疗组、常规针刺对照组。分别采用芒针合阳陵泉温针灸、常规针刺治疗,观察镇痛起效时间及综合疗效评价。结果：治疗组镇痛起效时间短于对照组,综合疗效评价优于对照组,差异有显著性意义。结论：芒针合阳陵泉温针灸对腰椎间盘突出症根性痛具有较好的镇痛效果。     

杨兆钢教授芒针透穴法经验举隅

芒针疗法是祖国传统针灸学中的一枝奇葩,它在主导思想、针具、针法、针刺深度、选穴配方上与毫针有显着区别,对许多疾病疗效优越.天津中医学院第一附属医院芒针科主任杨兆刚教授,30年来对芒针疗法进行发掘、整理和提高,取得了令人瞩目的成绩.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.