Sleep apnea, cardiac arrhythmias, and conduction disorders

Sleep apnea (SA) is a common breathing disorder. It is associated with a myriad of medical conditions including increased cardiovascular morbidity and mortality. Recent studies have shown that cardiac arrhythmias and conduction disorders are common in patients with SA. Sleep apnea has also been also linked to heart failure, hypertension, coronary artery disease, and stroke. The purpose of this brief review is to analyze the available information that links SA with different cardiac arrhythmias and conduction disorders and the role of intracardiac devices for the diagnosis and management of this condition.     

Somatic syndromes,insomnia, anxiety,and stress among sleep disordered breathing patients

Sleep and Breathing - We tested the hypothesis that the prevalence of somatic syndromes, anxiety, and insomnia among sleep disordered breathing (SDB) patients is correlated with their levels of...     

Prospective associations of sleep apnea,periodic limb movements,and plasma fibrinogen level

Sleep and Breathing - Our previous cross-sectional study showed that periodic limb movements during sleep (PLMS) were frequently found in patients with obstructive sleep apnea (OSA) and that both...     

Effects of nasal high flow on sympathovagal balance,sleep, and sleep-related breathing in patients with precapillary pulmonary hypertension

Sleep and Breathing - In precapillary pulmonary hypertension (PH), nasal high flow therapy (NHF) may favorably alter sympathovagal balance (SVB) and sleep-related breathing through washout of...     

The effect of daily fast food consumption,family size,weight-caused stress,and sleep quality on eating disorder risk in teenagers

Sleep and Breathing - Eating disorder (ED) is a common complication with disturbance of eating or eating-related behaviors that lead to physical and psychosocial disorders. The purpose of this...     

Association between anxiety,depression, and emotional distress and hypoglossal nerve stimulator adherence

Sleep and Breathing - To evaluate relationships between hypoglossal nerve stimulator (HNS) adherence and the presence of anxiety, depression, and emotional distress. This is a cross-sectional study...     

Sleep habits,fatigue, and sleepiness in Chiclayo-Peru’s bus drivers

Sleep and Breathing - The objectives of the study are to describe sleep habits, fatigue, and sleepiness in Chiclayo’s (Peru) bus drivers and explore their relation with traffic accidents....     

High risk of obstructive sleep apnea,insomnia, and daytime sleepiness among commercial motor vehicle drivers

Sleep and Breathing - We investigated the prevalence of sleep problems, such as obstructive sleep apnea (OSA), insomnia, and daytime sleepiness in commercial motor vehicle (CMV) drivers compared...     

Sleep duration,obesity, and asthma,in Florida adolescents: analysis of data from the Florida Youth Risk Behavior Survey (2009–2013)

Sleep and Breathing - To examine the association between sleep duration and asthma among Florida high school students and whether body mass index (BMI) modifies this association. This...     

Sleep fragmentation, awake blood pressure, and sleep-disordered breathing in a population-based study

Arousal from sleep produces transient increases in systemic blood pressure, leading to the suggestion that repeated arousals are associated with a sustained increase in daytime blood pressure. Using data from the Wisconsin Sleep Cohort Study, a population-based study, we tested the hypothesis that sleep fragmentation is associated with elevated awake blood pressure. Sleep, breathing, and seated blood pressure measurements from 1,021 participants (age 42 +/- 8 yr; 590 males) were analyzed. Sleep fragmentation was defined as the total number of awakenings and shifts to Stage 1 sleep divided by the total sleep time (sleep fragmentation index: SFI). To reduce the confounding influence of sleep-disordered breathing, which is related to both increased daytime blood pressure and sleep fragmentation, all participants with an apnea-hypopnea index (AHI) > or = 1 were analyzed separately. Accounting for the influences of sex, age, body mass index, and antihypertensive medication use, the SFI was significantly associated with higher levels of awake systolic blood pressure in people with an AHI < 1; a 2 standard deviation increase in the SFI was associated with a 3.1 mm Hg rise in awake systolic blood pressure. In participants with an AHI > or = 1, there was no independent association between the SFI and awake blood pressure after controlling for the influence of the AHI.     

The relationship between anxiety,depression, daytime sleepiness in the REM-related mild OSAS and the NREM-related mild OSAS

Sleep and Breathing - Obstructive sleep apnea syndrome (OSAS) is a common form of sleep-related respiratory disease characterized by recurrent blockages in the upper airway. Rapid eye movement...     

睡眠时长和午睡与代谢综合征相关性的研究进展

MS是一组心血管疾病危险因素,近年来发病率不断升高。睡眠是调节人体新陈代谢的重要生理过程。随着人们生活方式改变,睡眠不足或睡眠质量下降逐渐增加。睡眠时长、午睡与MS患病风险相关。本文对睡眠时长和午睡与MS相关性的研究进展进行综述。     

Excessive daytime sleepiness in general hospital nurses: prevalence,correlates, and its association with adverse events

Sleep and Breathing - To investigate the prevalence and correlates of excessive daytime sleepiness (EDS) in a population of hospital nurses in South China as well as the influence of EDS on the...     

Nighttime sleep duration,daytime napping,and metabolic syndrome: findings from the China Health and Retirement Longitudinal Study

Sleep and Breathing - This study aimed to assess the association between nighttime sleep, daytime napping, and metabolic syndrome (MetS) in an elderly Chinese population. A cross-sectional study...     

Roles of interleukin (IL)-6 gene polymorphisms,serum IL-6 levels,and treatment in obstructive sleep apnea: a meta-analysis

Sleep and Breathing - Inconsistent results regarding the relationship between interleukin (IL)-6 gene polymorphisms, serum IL-6 levels, and the treatment in obstructive sleep apnea (OSA) have been...     

Effects of sleep and sleep deprivation on interleukin-6, growth hormone, cortisol, and melatonin levels in humans

The objective of this study was to evaluate the effects of nocturnal sleep, partial night sleep deprivation, and sleep stages on circulating concentrations of interleukin-6 (IL-6) in relation to the secretory profiles of GH, cortisol, and melatonin. In 31 healthy male volunteers, blood samples were obtained every 30 min during 2 nights: uninterrupted, baseline sleep and partial sleep deprivation-early night (awake until 0300 h). Sleep was measured by electroencephalogram polysomnography. Sleep onset was associated with an increase in serum levels of IL-6 (P < 0.05) during baseline sleep. During PSD-E, the nocturnal increase in IL-6 was delayed until sleep at 0300 h. Sleep stage analyses indicated that the nocturnal increase in IL-6 occurred in association with stage 1-2 sleep and rapid eye movement sleep, but levels during slow wave sleep were not different from those while awake. The profile of GH across the 2 nights was similar to that of IL-6, whereas the circadian-driven hormones cortisol and melatonin showed no concordance with sleep. Loss of sleep may serve to decrease nocturnal IL-6 levels, with effects on the integrity of immune system functioning. Alternatively, given the association between sleep stages and IL-6 levels, depressed or aged populations who show increased amounts of REM sleep and a relative loss of slow wave sleep may have elevated nocturnal concentrations of IL-6 with implications for inflammatory disease risk.     

Schlafmedizinische Aspekte bei COPD,Asthma bronchiale und allergischer Rhinitis

Bronchial asthma, allergic rhinitis and chronic obstructive pulmonary disease (COPD) are chronic diseases affecting millions of people around the world. Sleep plays an important modulatory role for these diseases. Circadian variations of respiration and pulmonary function may cause hypoventilation in COPD patients and may worsen asthmatic symptoms during sleep. Sleep disordered breathing is highly prevalent in all of these diseases. Finally, asthma, COPD and allergic rhinitis can contribute to the development of insomnia via multiple mechanisms. This article focuses on the complex relationships between these diseases and sleep and reviews the implications for diagnosis and therapy.     

Associations between hypoxia parameters in obstructive sleep apnea and cognition,cortical thickness,and white matter integrity in middle-aged and older adults

Sleep and Breathing - This study aimed to investigate the association between each parameter of intermittent hypoxia in obstructive sleep apnea (OSA) and the cognitive profile, cortical thickness,...     

Periodic limb movements in sleep are followed by increases in EEG activity,blood pressure,and heart rate during sleep

Sleep and Breathing - Periodic limb movements in sleep (PLMS) are related to arousal, sympathetic activation, and increases in blood pressure (BP), but whether they are part of the arousal process...