A CASE WITH ACUTE RENAL FAILURE COMPLICATED BY WALDENSTRÖM'S MACROGLOBULINEMIA AND CRYOGLOBULINEMIA

We encountered a 53-year-old man associated with acute renal failure caused by Waldenström's macroglobulinemia and type I cryoglobulinemia. Treatment with prednisolone and cyclophosphamide induced a rapid recovery from acute renal failure. Renal histology revealed endocapillary proliferation and lobular formation with scattered subendothelial, amorphous and periodic acid-Schiff (PAS)-positive materials in the glomerular capillaries which were positive for IgM on immunofluorescence study. Although the exact mechanism for pathophysiology of acute renal failure remains unknown, treatment with prednisolone and cyclophosphamide could induce a rapid recovery from acute renal failure accompanied by Waldenström's macroglobulinemia and type I cryoglobulinemia.     

Urban–rural differences in breast cancer incidence in Egypt (1999–2006)

ObjectiveTo describe urban–rural differences in breast cancer incidence in Gharbiah, Egypt and to investigate if these differences could be explained by known risk factors of breast cancer.MethodsWe used data from the population-based cancer registry of Gharbiah, Egypt to assess breast cancer incidence from 1999 through 2006. The Egyptian census provided data on district-specific population, age, and urban–rural classification. Incidence patterns of breast cancer by district and age-specific urban–rural differences were analyzed.ResultsOverall, incidence rate of breast cancer was three to four times higher in urban areas than in rural areas (60.9/10⁵-year for urban areas versus 17.8/10⁵-year for rural areas; IRR = 3.73, 95% CI = 3.30, 4.22). Urban areas had consistently higher incidence of breast cancer across all age-groups for all years. Higher incidence of breast cancer was also seen in the more developed districts of Tanta and El-Mehalla.ConclusionsHigher incidence of breast cancer in urban and more developed populations might be related to higher exposure to xenoestrogens, as well as other endocrine disruptors and genotoxic substances.     

Erratum: Korrektur von NOTFALL & RETTUNGSMEDIZIN (1999) 2:377–379

Ohne Zusammenfassung     

Ruptured abdominal aortic aneurysms in a private hospital: A decade's experience (1980–1989)

Despite refinements in elective resection of abdominal aortic aneurysms, morbidity and mortality rates for ruptured abdominal aortic aneurysms (RAAAs) remain high. Between January 1, 1980 and December 31, 1989, we treated 208 patients with RAAAs whose mean age was 70 years. The overall mortality rate was 49.5%. Logistic regression analysis showed that three factors correlated with predicted patient survival. Patients <70 years old had a survival rate of 65.7% compared with a survival rate of 37.4% in patients >70 years old (p<0.001). Among stable patients (preoperative blood pressure consistently >90 mm Hg), 88.9% survived compared with 40.9% of unstable patients (blood pressure <90 mm Hg) (p<0.001). Of the patients with free intraperitoneal rupture, 38.3% survived compared with a survival rate of 79.6% of patients with rupture confined to the retroperitoneum (p<0.001). Despite a high overall mortality rate in patients with RAAAs, surgical intervention remains the only hope for survival. We continue to advocate an aggressive surgical approach in this group of patients.     

Lung Cancer in Women: a Comparison with Men and an Analysis of Cases Diagnosed in Ourense (Spain) 1999–2006

Introduction and objectiveTo analyse the frequency, characteristics and survival of women with lung cancer (LC), compared with male patients.Patients and methodsA retrospective study was performed in patients with LC diagnosed by histocytology from 1999 to 2006. Survival was estimated by the Kaplan-Meier method. The chi-squared test was used to compare variables.ResultsA total of 1,290 patients were diagnosed; 190 (14.7%) of them were women, with a mean age of 67 ± 13. The percentage of smokers was 17%. Histological types included: adenocarcinoma 53%, small cell 21%, epidermoid carcinoma 13%. Surgery was performed (20%) in a higher percentage of women than in men. There were no differences in survival between the two groups.ConclusionsOf the total cases diagnosed, 14.7% were women, with a lower percentage of smokers. Adenocarcinoma was the most common histological type. There were no differences in survival compared to men.     

Abstracts presented at the Fifth International Conference on Geriatric Nephrology and Urology, 4–6 October 1999, Salamanca,Spain (part 3)

Abstract List

Abstracts presented at the Fifth International Conference on Geriatric Nephrology and Urology, 4–6 October 1999, Salamanca, Spain (part 3)