家兔急性实验时糖尿现象的激素机制

实验在急性实验条件下的10只兔身上进行,同时测定血清胰岛素、皮质醇和尿中VMA在手术后的变化;並对四只犬进行同样的观察。结果:手术后,家兔尿中的VMA含量逐渐升高,由9.0±3.02μg/ml升至23.4±6.78μg/ml,p<0.01;血清中的胰岛素含量则逐渐降低,由60.5±14.52μu/ml降为42.4±14.09μu/ml,P<0.05。犬的上述激素的含量变化与兔相反。兔和犬血清中皮质醇平均含量均有升高的趋势,但无统计学意义。表明兔在急性实验时儿茶酚胺的分泌增加,胰岛素的分泌减少,是导致其血糖浓度进行性升高,产生糖尿现象的激素机制。     

妊娠期纤溶状态的实验观察

应用纤溶活性比色定量分析法观察了132例早、中、晚期国人健康孕妇静脉血浆纤溶活性的变化。结果:孕期静脉血浆纤溶总活性呈持续性降低,纤溶抑制活性及纤溶酶原活性持续升高(P皆<0.01)。晚孕组纤溶激活活性显著降低(P<0.05)。证明孕期处于低纤溶状态。     

妊娠高血压综合征患者血小板超微结构

对18例妊娠高血压综合征(妊高征)患者,8名正常孕妇及7名正常非孕妇进行血小板形态学观察,发现孕妇组直径大于3.6μ的、伪足及储备颗粒较多的血小板的比例较非孕妇大,糖元含量也增多,提示血小板活性增高。妊高征组则储备颗粒增加更为显著,并见颗粒融合、开放小管中出现颗粒沉积及管泡样结构明显增多和扩张等,提示血小板释放增强。     

DOUBLE SACS AMNIOCENTESIS IN TWIN PREGNANCY

The maturity of twins is not the same, even in monozygote twins. In the management of high risk twin pregnancies, double sacs amnio- centesis becomes mandatory. Under B-scan ul- trasonography, the placenta as well as the dou- ble sacs are located. Amniocentesis is done for each sac, with injection of indigo carmine into the first sae for identification. Four cases of twin pregnancies were tapped with success. The amniotic fluid (AF) analytical results were listed. The neonates were examined for possible ill effect caused by the dye to the blood system, but there were none.     

AMNIOTIC EPITHELIUM IN TOXEMIA OF PREGNANCY

The epithelium of human amniOn from pa- tients following normal pregnancy (normal am- niotic epithelium) and from patients with toxe- mia were examined under the light and electron microscopes. In contrast to normal amniotic epithelium, the epithelium in toxemia exhibits the following morphologic changes: The cells are low cuboidal; the light cells are frequently seen; the microvilli on the free cell surfaces are inequally distributed; the nuclei are elongated and highly deformed, forming loops and lobes; there are no glycogen particles in the cytoplasm; and the basal membrane is thickened and in parts stratified.     

支气管哮喘合并妊娠的预后及处理

分析１９７１年～１９９４年间支气管哮喘合并妊娠５５例（０．１２％），发生率近年有增高倾向。妊娠期哮喘在早期稳定，孕晚期发作增多。产母及围产儿其他并发症均有增高，本组中、重度好高征１４例（２５．４５％），胎盘早剥３例（５．４５％），产后出血６例（１０．９ｌ％），产母及早产儿死亡各１例，子宫内生长迟缓（ＩＵＧＲ）１１例（１９．３０％）。因此哮喘合并妊娠后应按高危妊娠处理，加强围产期管理，避免上呼吸道感染，防治妊高征，哮喘发作期应及时有效治疗，加强供氧，监测胎儿胎盘功能，病情稳定者可以维持妊娠至足月，心肺功能不良应及时中断妊娠。     

320例孕早期绒毛细胞染色体分析

对296例人工流产及6例产前诊断的孕早期绒毛细胞采用直接法进行染色体分析,共有正常染色体290例,占96.02％,其中男性核型137例,女性核型153例,男女之比为1:1.12,男略少于女。共发现异常染色体12例,发生率为3.97％,其中数目异常11例,结构异常1例。30岁以上的孕妇染色体异常发生率明显高于30岁以下者,产前诊断组异常染色体发生率高于人工流产组,     

ULTRASONIC PLACENTAL GRADING IN HIGH RISK PREGNANCY

264 high risk pregnancy patients were studied by B mode ultrasound for placental grading and bipa. rietal diameter (BPD) measurement. The Lecithin- sphingomyelin (L/S) ratio, phosphatidyl-glycerol (PG) and foam test were performed with 81 cases as control. Repeat cesarean sections were performed in 44 patients who did not have amniocentesis and their operation timing was based only upon placental grad ing, biparietal measurement and clinical examination. No respiratory distress syndrome (RDS) occurred in this group after delivery. This study shows that when BPD of > 8.7 cm is combined with I, II, or III pla. cental grading neonatal Dubowitz scores correspond t0 38 weeks; neonatal birth weight is greater than 2,500 g and there is no RDS. Combined BPD of > 8.5 cm with a Grade III placenta preclude the neces. sity for amniocentesis to prove fetal lung maturity. Grade III placenta is more common iri postdatism, chronic hypertension and preeclampsia and less common in diabetics.     

孕前体重指数对初次妊娠妇女妊娠结局的影响

目的：探讨初次妊娠妇女待孕前体重指数对妊娠结局的影响。方法：采用回顾性群组研究方法,对2000—2006年间,在牡丹江中医院产前门诊就诊并在其院部分娩单胎的839名初次妊娠的育龄妇女进行了研究。这些妇女按体重指数分成五组：偏轻组（BMI〈18．5kg／m^2）、正常组（BMI=18．5—23．9kg/m^2）、超重组（BMI=24～27．9kg／m^2）、肥胖组（BMI=28～31．9kg／m^2）、和病态肥胖组（BMI≥32kg／m^2）。使用单变量和多变量分析对比各组对妊娠结局的影响。结果：和正常组妇女相比,病态肥胖组妇女患妊娠高血压疾病{0114．37（95％CI1．32,14．41）}和妊娠期糖尿病{OR6．01（95％CI1．95,18．52）}的风险极高,而体重偏轻组妇女的患病风险最低。病态肥胖组妇女引产几率最高{OR2．94（95％CI1．02,8．48）},体重偏轻组妇女引产几率最低。病态肥胖组妇女剖腹产几率最高{OR3．22（95％CI1．13,9．22）},体重偏轻组妇女剖腹产几率最低。病态肥胖组妇女更容易患产后出血症{OR4．05（95％CI1．08,15．20）}和早产{OR5．55（95％CI1．14,27．15）}。病态肥胖组妇女分娩巨大儿的风险最高{OR5．55（95％CI1．14,27．15）},而体重偏轻组妇女风险最低。体重偏轻组妇女分娩低体重儿的风险最高{OR5．14（95％CI1．26,20．92）}。结论：孕妇体重指数的增加相应带来妊娠期高血压疾病、妊娠期糖尿病、巨起儿、引产、剖腹产发生率的增加。与拥有正常体重指数的妇女相比,体重偏轻的妇女有比较好的妊娠结局。     

正常妊娠及妊高征患者产后胰岛素抵抗的变化

目的 研究正常妊娠及妊高征患者产后胰岛岛素抵抗的变化及特点。方法 选取正常未孕１２例,正常妊娠及妊高征各３０例,分别于产前、产后第１,３,５天抽取空腹血,应用氧化酶法测血糖,放免法测血胰岛素、ｃ－肽水平。结果 正常妊娠及妊高征者妊娠晚期存在胰岛素抵抗,妊高征者抵抗程度较重。正常妊娠产后第３天胰岛素、ｃ－肽明显下降（Ｐ〈０．０５）,同征组产后第１天胰岛素、ｃ－肽即明显下降（Ｐ〈０．０５）,与正常妊娠     

ACTION OF ANTI-HCG MONOCLONAL ANTIBODY IN BLOCKING PREGNANCY IN MIICE

This papvr presents the effect of hCG McAb which was prepared in our laboratory on pregnancy and embryo development in mice.     

1988～1990年上海县三林、七宝和曹行乡高危妊娠筛查和妊娠结局

对1988至1990三年间上海县三林乡、七宝乡和曹行乡的孕产妇登记资料进行了分析,在登记的2392名孕妇中,筛出各类高危孕妇572例(占23.9％),分析表明,三个乡的高危筛出率明显不同,可能系筛检标准掌握尺度不一,高危评分其得分高低与异常妊娠结局的发生率间关系不明显,分析还显示高危妊娠的孕妇中异常妊娠结局发生率高于正常孕妇。