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《RSC advances》2022,12(32):20956
We would like to take this opportunity to highlight the Outstanding Reviewers for RSC Advances in 2021, as selected by the editorial team for their significant contribution to the journal.We would like to take this opportunity to thank all of RSC Advances’s reviewers, and in particular highlight the Outstanding Reviewers for the journal in 2021, as selected by the editorial team for their significant contribution to RSC Advances. We announce our Outstanding Reviewers annually and each receives a certificate to give recognition for their contribution. The reviewers have been chosen based on the number, timeliness and quality of the reports completed over the last 12 months. Dr Gopi AdhikariUniversity of Nebraska-LincolnORCID: 0000-0002-9986-8218 Dr Marco AnniUniversità del SalentoORCID: 0000-0002-1651-0166 Dr Jubaraj BaruahIndian Institute of Technology GuwahatiORCID: 0000-0003-3371-7529 Dr Mauro ChinappiUniversità degli Studi di Roma Tor VergataORCID: 0000-0002-4509-1247 Professor Søren ChristensenKøbenhavns UniversitetORCID: 0000-0002-5773-6874 Professor Beelee ChuaKorea UniversityORCID: 0000-0002-9153-0167 Dr Francesco FerlinUniversità degli Studi di PerugiaORCID: 0000-0003-3800-9708 Dr Lihua GanTongji University Dr Charles GauthierInstitut National de la Recherche ScientifiqueORCID: 0000-0002-2475-2050 Dr Xuyun GuoThe Hong Kong Polytechnic UniversityORCID: 0000-0003-0365-7545 Professor Wei-Min HeUniversity of South ChinaORCID: 0000-0002-9481-6697 Dr Bolong HuangThe Hong Kong Polytechnic UniversityORCID: 0000-0002-2526-2002 Professor Dong-Hau KuoNational Taiwan University of Science and TechnologyORCID: 0000-0001-9300-8551 Dr Dattatray LateNational Chemical Laboratory CSIRORCID: 0000-0003-3007-7220 Professor Giuseppe LazzaraUniversità degli Studi di PalermoORCID: 0000-0003-1953-5817 Dr Xin LiuUniversity of FloridaORCID: 0000-0001-9504-795X Dr Nadia Mahmoud Tawfiq JebrilUniversity of PlymouthORCID: 0000-0002-5368-2127 Dr Ramakanta NaikInstitute of Chemical Technology Mumbai - IndianOil Odisha Campus BhubaneswarORCID: 0000-0002-4460-1540 Dr Yangguang OuUniversity of VermontORCID: 0000-0002-6902-3978 Dr Paresh SamantarayIndian Institute of ScienceORCID: 0000-0003-2533-929X Dr Dane ScottEast Tennessee State University College of Arts and SciencesORCID: 0000-0003-0018-7189 Dr Rodolfo TeixeiraUniversity of NottinghamORCID: 0000-0001-8042-8442 Dr Carlos Torres-TorresInstituto Politécnico NacionalORCID: 0000-0001-9255-2416 Dr Renjie WangVirginia Commonwealth UniversityORCID: 0000-0002-2969-0987 Dr Zhixin WangUniversity of FloridaORCID: 0000-0001-7255-6049 Dr Biquan XiongHunan Institute of Science and TechnologyORCID: 0000-0002-6490-6384 Dr Li-Ming YangHuazhong University of Science and TechnologyORCID: 0000-0002-7836-212X Dr Zhi YueThe University of ChicagoORCID: 0000-0002-4231-7474 Dr Wen ZhangTianjin UniversityORCID: 0000-0001-6118-3136 Professor Guowei ZhouQilu University of TechnologyORCID: 0000-0002-7023-6225 We would also like to thank the RSC Advances Editorial Board and Advisory Board and the research community for their continued support of the journal, as authors, reviewers and readers. Russell Cox, Editor-in-ChiefLaura Fisher, Executive Editor 相似文献
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James Batteas 《RSC advances》2022,12(35):22590
RSC Advances is proud to present the 2021 Emerging Investigators series. Guest Edited by Professor James Batteas (Texas A&M University), this series showcases some of the very best work from chemists in the early stages of their independent careers.We are so pleased to introduce this first issue of our RSC Advances Emerging Investigators series! Launched in 2021, the series seeks to highlight up and coming researchers. Selection for the Emerging Investigators series comes in part from the recommendations of our Editorial Board as well as our Associate Editors. Authors can also self-nominate for participation and review by our Associate Editors for the journal. In keeping with the theme of RSC Advances as a cross-cutting chemistry journal, in this inaugural issue we have 23 papers spanning the breadth of chemistry on topics ranging from the development and application of analytical tools and devices for chemical analysis, to the design and synthesis of bioactive materials for disease treatments, to catalysis and synthesis of new materials.We introduce the 2021 series with a Review article by Dusselier et al. (https://doi.org/10.1039/D1RA02887A) which discusses the ambiguity in our current understanding of the mechanisms behind interzeolite conversion as a technique for the synthesis of zeolite frameworks. This article highlights how heteroatoms such as aluminium have important roles in this process.We then launch into a series of analytical contributions to introduce the primary research papers in this collection. Paixão et al. (https://doi.org/10.1039/D0RA08874A) explore the development of electrochemical paper-based analytical devices for low-cost electrochemical sensing, in which even pencil-drawn electrodes can be used for device fabrication. Lewis et al. (https://doi.org/10.1039/D1RA04470B) show how 2D tin sulfide nanosheets can be assembled using simple Langmuir–Blodgett techniques to create novel, solution processed photodetectors. Next, Lucena et al. (https://doi.org/10.1039/D1RA02721B) discuss how chemically functionalized hypodermic needles can be used for selective extraction of tricyclic antidepressant (TCA) drugs from oral fluid as a simple and convenient approach for in-needle microextractions, allowing the samples to be further rapidly analyzed by mass spectrometry. Rapid screening of chemical compounds is of course an essential component of understanding and identifying materials for protein assays. To this end, Trader et al. (https://doi.org/10.1039/D0RA10976B) developed one-bead-one-compound (OBOC) libraries in which a target oncoprotein, gankyrin, is labeled with a NIR range fluorophore, and screened against a 343-member peptoid library to afford a method to quickly identify quality binders to a target protein of interest. Tsai et al. (https://doi.org/10.1039/D1RA04875A) developed an acoustofluidic method for the detachment of cells adhered onto a microchannel surface, without exposing the cells to any enzymatic or non-enzymatic compounds. This approach demonstrates a rapid, easy-to-operate, and cost-effective means of detaching or probing the adhesion strength of different cell types in various lab-on-a-chip applications. Lastly, Gupta et al. (https://doi.org/10.1039/D1RA08610C) prepare hydrogel gratings with an analyte responsive dye. The patterned dye is its own dispersive element, and therefore can enable the gratings to provide spectroscopic information without the use of external spectrophotometers.Synthesis of new materials is of course a cornerstone of chemistry, and in the work highlighted in this issue, we see studies from Rodrigues et al. (https://doi.org/10.1039/D0RA10859F) in which carbon dots (C-dots) could be synthesized from a variety of carbon sources, which when functionalized with phenylboronic acid (PBA) yielded a highly efficient glucose sensor via bioimaging, and also offer the potential for cancer treatment as they could be used to induce necrosis in tumor tissues in cancer-bearing mice. Continuing in the theme of cancer treatments, Pianowski et al. (https://doi.org/10.1039/D0RA08893E) demonstrated that nontoxic supramolecular low-MW hydrogels could be used to quickly and selectively release potent anticancer agents upon light irradiation. Similarly, Sarkar et al. (https://doi.org/10.1039/D1RA01660A) synthesized an amphiphilic polymer, poly(PEGMA-co-SEMA) (BCP), by controlled reversible addition fragmentation chain transfer (RAFT) polymerization. The core–shell supramolecular assembly polymeric nano-architecture formed could be used as an efficient delivery system for anticancer drugs like doxorubicin (DOX). While polymeric materials can act as drug delivery agents, they can also act as protective coatings, as Heredia et al. (https://doi.org/10.1039/D1RA03417K) show in their work in which antimicrobial coatings could be created using films of PEDOT–fullerene C60 polymeric dyads. These films enable surface coatings that are self-sterilizing, as pathogens can be inactivated using the photodynamic activation of reactive oxygen. Here the authors demonstrated photosensitized inactivation by the electropolymerized films on bacteria suspensions with a >99.9% reduction in S. aureus survival. Finally, Pal et al. (https://doi.org/10.1039/D1RA07425C) develop some hydrophobic polymers with low glass transition temperatures that can be used in photovoltaic devices, where systems with smart polymeric coatings can optimize durability and efficacy. The polymers that they develop display photo-regulated self-healing mechanisms.Sustainable synthesis also continues to be a major theme in chemistry and in this issue, Egbedina et al. (https://doi.org/10.1039/D1RA01130H) use ZnO biochar (made from coconut husks, kaolinite and ZnCl2) to make materials for wastewater treatment to remove unused antibiotics. Cleanup of plastics from water is also a critical challenge facing us, and Tiwary et al. (https://doi.org/10.1039/D1RA03097C) show how a schwarzite based 3D-printed water filter can be used for the cleanup of nanoplastics. But sustainability goes beyond just remediation. Hahn et al. (https://doi.org/10.1039/D1RA03692K) show that the immobilization of polyketide synthase through crosslinking could yield recyclable catalysts for chiral synthesis. In addition to being environmentally more benign, cost savings through the design of new scalable catalysts are also impactful. Zhang et al. (https://doi.org/10.1039/D1RA04112F) show us how efficient cross-coupling of aryl halides can be accomplished with high selectivity and low cost using a new atomically dispersed copper catalyst (Cu–ZnO–ZrO2).The design of materials also takes on key challenges in discovering critical structure/function relationships. For example, Luo et al. (https://doi.org/10.1039/D1RA03366B) examine how plastic crystals of neopentyl glycol (NPG) can exhibit high ionic conductivities, making them promising candidates for applications in fuel cells, batteries, and supercapacitors. In terms of controlling unique optical properties of materials, Leitao et al. (https://doi.org/10.1039/D1RA02961D) was able to synthesize stable naphthalene bridged disilanes, capable of forming stable excimer complexes in non-polar solvents. The materials provide opportunities to create novel light emitting devices and/or photocurrent generators for solar cells. Around the development of supramolecular luminescent materials in water, hydrophobic chromophores can present a number of issues that limit their performance in aqueous media. Research in this collection by Xiao et al. (https://doi.org/10.1039/D1RA06239E) describes the development of a water-phase artificial light-harvesting system that can work efficiently in water, opening up more possibilities for dynamic luminescent materials.The development of artificial supramolecular systems that can mimic the power of enzymes is an important field of development for a number of applications. In the contribution by Hu et al. (https://doi.org/10.1039/D1RA07958A), two water-soluble pillar[5]arenes with peripheral rims that contain opposite charges are prepared, and investigation of their influence on the Kemp elimination reaction of 1,2-phenylisoxazole derivatives was studied, helping to advance this area of research. Insight into reaction mechanisms using computational studies is central to advancing chemistry. Wang et al. (https://doi.org/10.1039/D1RA04564D) use multi-scale simulations to expand our understanding of P450-catalyzed C(sp3)–H amination reactions, through an optimized understanding of the P450-mediated amination of the pyrrolidine derivative of lidocaine. Globisch et al. (https://doi.org/10.1039/D1RA05994G) carry out analysis of the sulfated metabolites in various biological samples, as sulfated metabolites have been identified as being an identifier of the co-metabolism between the microbiome and its host. Through this, they are able to identify the core sulfatome of 41 metabolites. This brings us to our final contribution to this issue from Beemelmanns et al. (https://doi.org/10.1039/D1RA00997D) which highlights how using data screening methods such as Global Natural Products Social Molecular Networking Analysis (GNPS) can reveal key bioactive molecular species, in this case focused on metabolic studies of Pseudoxylaria sp. X187.We hope that you find this issue inspirational for both the breadth and high quality of chemistry described by these up-and-coming researchers, and we look forward to expanding this series in the years to come. 相似文献
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《Mayo Clinic proceedings. Mayo Clinic》2019,94(12):2598-2601
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Professor Hélder A. Santos and Dr Irina N. Savina introduce the RSC Advances themed collection on Nanomaterials in drug delivery.Research on nanomaterials for drug delivery applications has exponentially increased in the last few years, particularly since the impactful lipid nanocarriers used by Pfizer and Moderna were developed for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines to treat COVID-19.1There is ongoing research into the development of effective drug delivery systems that will help us deal with complex and life-threatening diseases, such as cancer, diabetes and cardiovascular diseases.2 Nanomaterials like liposomes, polymeric nanoparticles, metal nanoparticles, micelles, emulsions and dendrimers are becoming increasingly important in the pharmaceutical industry for improving drug formulations. The use of nanomaterials enhances the properties of conventional drugs through improved targeted drug delivery, solubility, bioavailability and drug retention time, and at the same time contributes to a reduction in side effects and risks of drug toxicity.Nanoparticles have been produced using a variety of technologies, and particles will be formed by self-assembly, emulsification or precipitation. The choice of method is based on the ability to produce particles at the nanoscale with controlled size and good reproducibility at large scales. As an alternative to batch synthesis, microfluidic technology has been proposed, which allows better control of nanoparticle production and production on a large scale. Research continues to improve the methods available and develop more modern technologies. Grandi and co-workers demonstrated the potential of centrifugal flow-through reactors (RIACs) as a cost-effective, facile and pump-free technology for producing pharmaceutically relevant nanoparticulate systems. RIACs can be manufactured using a desktop 3D printer without post-manufacturing treatment before usage, which makes RIACs an appealing technology to research groups, especially in low-resource settings and without prior expertise in microfluidics (https://doi.org/10.1039/D2RA02745C).Various polymers have been used for the design of nanoparticles. The main focus is on biocompatible, biodegradable, non-toxic and non-immunogenic polymers. Tortorella and co-workers review the literature work on the very recent applications of zein as an attractive and promising biopolymer for biomedical applications, and its advantageous properties in terms of shape and size, from the 1D to the final 3D perspective, including discussion of zein nanoparticles and nanocomplexes, fibers, films, membranes, microbeads, gels, and scaffolds (https://doi.org/10.1039/D1RA07424E).Nanotechnology is key to the development of RNA therapy, which uses RNA-based delivery molecules to treat or prevent diseases that cannot be treated with conventional drugs. Recent advances in biotechnology and molecular biology make it possible to produce any peptide or protein in human cells by introducing RNA as a therapeutic agent or vaccine. The ability to produce programmed exogenous RNA and deliver it using non-viral delivery systems is more cost effective, is faster and provides flexibility in the design, something that cannot be offered by other conventional approaches. Because of that, RNA therapy can provide a quick response to the outbreak of infectious disease, such as the recent outbreak of COVID-19. RNA therapy offers hope for the development of a cure for intractable or genetic diseases. A number of RNA treatments have been successfully developed, and several clinical trials are currently underway. The review paper by Rajendran and co-workers discusses and provides an update on how mRNA therapeutics have evolved over time and the various strategies that are being explored to overcome the bottlenecks faced in utilizing mRNA as an efficient therapeutic aid, including the integration of bone tissue engineering biomaterials with mRNA for better localized delivery. The review also discusses the methods used for co-delivery of mRNA and for producing mRNA protecting proteins, and the future possibilities of utilizing mRNA therapeutics for treating various bone related genetic disorders (https://doi.org/10.1039/D2RA00713D). Research is ongoing to find more effective nanoformulations and better targeted delivery. Modification of nanoparticles with bioactive cell-recognizing molecules such as RGD improves delivery efficiency and tissue specificity in some applications (https://doi.org/10.1039/D2RA02771B). Further advances in the development of RNA drug-delivery systems will provide a solution for developing therapies for currently uncured diseases.In the past few decades, there has been interest in using exosomes, biological nanoparticles, as novel drug delivery systems. Exosomes are cellular drug delivery systems that are used by cells to communicate and also to transport some material. As part of a cell, exosomes have low toxicity, high bioactivity, and biocompatibility. Due to their structure, exosomes do not need to be modified with specific antibodies or other biologically active molecules for targeted delivery to specific cells. Growing knowledge of the structure and biological activity of exosomes is driving researchers to develop new structures of drug delivery systems and improve existing liposome-based delivery platforms. Hybrid variants have been created in an attempt to combine the advantages of the original exosomes with the properties of synthetic systems for better and more specific drug delivery. The review paper by Lee and co-workers provided an overview of the methods for the preparation of exosome-based drug delivery systems (DDSs) through encapsulation and loading of drugs into exosomes as well as the synthesis of hybrid exosomes through diverse approaches. They also discuss the effects of treatment using exosome-based DDSs in different diseases (https://doi.org/10.1039/D2RA02351B).This themed collection aims to explore the latest developments in the design, preparation, and application of nanomaterials for drug delivery, understand bio–nano interactions and biosystem parameters, assess the safety of nanomedicine, and assess the potential limitations of nanomedicine fabrication, including technical and legal aspects. There are currently 7 amazing contributions, including 3 review papers and 4 full papers, which broadly cover the various important topics within the field of nanomaterials in drug delivery. We would like to thank all the authors for their high-quality contributions, and we hope that researchers working in the areas of nanomaterials and drug delivery systems will enjoy reading these articles and find them useful for their future work. 相似文献
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《RSC advances》2021,11(39):24054
Celebrating the 10th anniversary of RSC Advances.In July 2011 the Royal Society of Chemistry published the first issue of RSC Advances,1 so this month marks our 10th anniversary! Since 2011 we’ve published over 62 000 articles across the breadth of the chemical sciences. We’ve got a lot of activities planned to celebrate our 10th year, but we’d like to start by sharing some of the history of our journal, and how we got to where we are today. 相似文献
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