Ultrasound Morphology of Polycaprolactone Filler

Nowadays, cosmetic fillers are widely used and the reports of complications are rising. Therefore, the possibility to detect and identify noninvasively new fillers can provide a potent tool for managing complications. The objective of this study was to assess the ultrasound morphology of polycaprolactone. First, polycaprolactone was injected into porcine skin and this sonographic morphology was prospectively compared with the one observed in patients injected with this filler. On sonography, polycaprolactone shows as hypoechoic deposits that present multiple bright hyperechoic spots with mini‐comet‐tail artifact. This morphology differs from the ultrasound appearance of other common fillers.     

Two‐Dimensional and Three‐Dimensional Ultrasound of Artificial Skin

Wound healing may be a difficult problem, and variable types of artificial skin prototypes have been developed for supporting this process. Using ultrasound, we studied 4 cellulose‐derived artificial skin prototypes and assessed their two‐dimensional and three‐dimensional morphology. These prototypes were identified on ultrasound both on in vitro and in vivo studies. They allowed the sonographic observation of deeper layers on different types of surfaces of the body with good definition on the in vivo examinations performed on healthy skin and cutaneous ulcers. The ultrasound detection of these artificial biomaterials may potentially support the noninvasive monitoring of wound healing.     

Very High‐ and High‐Frequency Ultrasound Features of Cutaneous Larva Migrans

Cutaneous larva migrans is a common infestation among travelers. Although the diagnosis may be suspected clinically, cases can show atypical presentations. We present the ultrasound features of 4 cases at 18 and 70 MHz. Small linear hyperechoic and hyper‐refringent subepidermal and intrafollicular structures suggestive of fragments of larvae, hypoechoic dermal and hypodermal tunnels that match with dilatation of lymphatic ducts, and inflammatory dermal and hypodermal ultrasound signs can support the diagnosis. This work suggests that larvae can penetrate the cutaneous basement membrane through the ostia of the hair follicles and potentially disseminate through the dermal and hypodermal lymphatic network.     

High‐Frequency Ultrasound in Blistering Skin Diseases: A Useful Method for Differentiating Blister Locations

Bullous pemphigoid and pemphigus vulgaris, which belong to the group of subepidermal and intraepidermal bullae, respectively, are two potentially devastating blistering skin diseases. We used high‐frequency ultrasound (US) in 3 cases of these diseases as prototypes to study the value of high‐frequency US in discriminating blister locations. Our findings showed that high‐frequency US has a strong correlation with histomorphometric findings because of its high resolution, and we hope that it will be helpful for differentiating blister locations.     

经阴道彩色多普勒超声诊断异位妊娠的临床价值

目的探索经阴道彩色多普勒超声诊断异位妊娠的临床价值。方法 2011年1月-2011年12月到我院我妇科门诊的异位妊娠患者160例,随机分为经阴道彩超组和经腹彩超两组,每组各80例,比较二者的检出率。结果经腹彩超符合率为85%,经阴道彩超总的诊断符合率为97.5%,二者相比差异有统计学意义(P<0.05)。结论经阴道彩超的诊断符合率显著优于经腹彩超,将二者联合应用,以提高异位妊娠的临床诊断符合率。     

Correlation of Quantitative Texture Analysis of Cranial Ultrasound With Later Neurobehavior in Preterm Infants

The purpose of the study was to evaluate the association between a quantitative texture analysis of early neonatal brain ultrasound images and later neurobehavior in preterm infants. A prospective cohort study including 120 preterm (<33 wk of gestational age) infants was performed. Cranial ultrasound images taken early after birth were analyzed in six regions of interest using software based on texture analysis. The resulting texture scores were correlated with the Neonatal Behavioural Assessment Scale (NBAS) at term-equivalent age. The ability of texture scores, in combination with clinical data and standard ultrasound findings, to predict the NBAS results was evaluated. Texture scores were significantly associated with all but one NBAS domain and better predicted NBAS results than clinical data and standard ultrasound findings. The best predictive value was obtained by combining texture scores with clinical information and ultrasound standard findings (area under the curve = 0.94). We conclude that texture analysis of neonatal cranial ultrasound-extracted quantitative features that correlate with later neurobehavior has a higher predictive value than the combination of clinical data with abnormalities in conventional cranial ultrasound.     

Common applications of dermatologic sonography

In recent years, there has been growing use of sonography in the dermatologic field. Thus, this review analyzes the most common dermatologic applications of sonography with some technical considerations for performing this type of examination. Moreover, the sonographic findings in common benign and malignant skin tumors, inflammatory dermatologic diseases, and ungual and cosmetic conditions, among others, are considered. Thus, this noninvasive technique may be a potent adjunctive tool in the diagnosis and management of dermatologic conditions in daily practice, delivering critical information otherwise unavailable to the clinical naked eye.     

恶性滋养细胞肿瘤的彩色多普勒血流图分型及其临床意义

应用彩色多普勒超声对30例恶性滋养细胞肿瘤的血管形态学改变进行了观察及分型，对其峰值血流速度及阻力指数进行了测定，定量测量血β-HCG水平监测化疗反应，23例葡萄股清宫术后恢复正常患者作为对照组。结果表明：①滋养细胞肿瘤血流图分为三型：弥漫型、血窦型、及实质型；②11例获病理诊断，包括1例弥漫型及5例血窦型结果为恶性葡萄胎，4例实质型，3例为绒毛膜癌，1例为化疗后变性坏死物；③不同类型血流阁与血β-HCG、子宫血流动力学改变及对化疗的反应相关性好。     

多重PCR结合基因芯片技术检测11种致病菌方法的建立

目的建立一种运用多重PCR方法结合基因芯片技术快速、准确检测11种常见致病菌的方法。方法筛选志贺氏菌、肠炎沙门氏菌、伤寒沙门氏菌、大肠杆菌O157、副溶血性弧菌、普通变形杆菌、蜡样芽孢杆菌、金黄色葡萄球菌、单核细胞增生李斯特菌、产气荚膜梭菌、空肠弯曲菌的特异基因作为目的基因。设计相应的引物及探针,进行多重PCR扩增,制备寡核苷酸芯片。将多重PCR扩增产物与带有11种特异探针的基因芯片杂交。用扫描仪扫描,判定细菌种类。结果该基因芯片可特异性地检测11种致病菌,具有良好的特异性,基因组DNA检测灵敏度可达2×10-3ng。结论多重PCR结合基因芯片技术检测11种不同致病菌的方法特异性好,灵敏度高,具有较好的实用性。