内镜逆行胰胆管造影术诊疗胆胰疾病

目的 评价内镜逆行胰胆管造影(ERCP)和内镜括约肌切开术(EST)在诊断及治疗胆胰疾病中的价值.方法 对比分析ERCP及EST术与术前B超、CT及MRCP检查的准确性.结果 61例中58例ERCP造影成功,造影成功率95.1%,2例取石失败,3例未取净,其中9例行CT,25例行MRCP检查.B超、CT和MRCP与ERCP的总符合率分别为67.2%、77.8%和92%(23/25),其中MRCP对结石诊断符合率93.3%(14/15),对炎性狭窄诊断符合率100%(9/9).ERCP检查术后并发症发生率为3.3%,MRCP术后无并发症发生.结论 ERCP和EST诊断胆胰疾病准确率高,患者痛苦小,对胆总管结石的治疗安全有效;MRCP为无创检查,对胆管内疾病的诊断几可达到ERCP诊断水平,但不能进行治疗.     

经内镜逆行胰胆管造影术与磁共振胰胆管造影术对胆胰疾病的诊断价值

目的比较经内镜逆行胰胆管造影术(ERCP)与磁共振胰胆管造影术(MRCP)对胆胰疾病的诊断价值。方法回顾性分析2013年1月-2014年12月我院收治的50例胆胰疾病患者同时进行ERCP、MRCP检查,比较这两种检查对胆胰疾病的诊断价值。结果 ERCP和MRCP诊断结果相同的患者有37例,符合率为86.05%。与胆胰疾病确诊例数相比,ERCP诊断符合率为97.73%,MRCP诊断符合率为84.09%,两者相比差异无统计学意义(P>0.05)。结论 ERCP与MRCP对胆胰疾病诊断价值相当,各有优缺,临床应做到ERCP与MRCP优势互补,提高胆胰疾病的诊断。     

MRCP与ERCP对胆胰系疾病的诊断价值

目的：比较磁共振胰胆管造影术（MRCP）与内镜下逆行性胰胆管造影术（ERCP）对胆胰系疾病的诊断价值。方法：对95例疑有胆胰系疾病的患 ,MRCP后4小时内行ERCP,其中2例患者因ERCP未成功而改行PTC,非屏气MRCP,采用最大强度投影（MIP）技术进行处理,获得胆胰系结构图像。ERCP采用常规方法进行,最后将MRCP影像与ERCP影像进行比较。结果MRCP与ERCP诊断总符合率为77．89％（74／95）,对恶性狭窄的诊断符合率为78．8％（29／37）,对结石的诊断符合率为82．14％（23／28）。MRCP的敏感性为80％,特异性为32．14％,准确性为71．11％,阳性预测值为75．95％,阴性预测值为32．14％,阳性拟然比为1．18,阴性拟然比为0．62。结论：MRCP为无创性检查,漏诊率虽然低,但误诊率却相对较高。目前在胆胰系疾病的诊断中,MRCP尚不能取代ERCP。再者,ERCP在胆胰系疾病治疗上的作用也是MRCP无法比拟的,且随着分子生物学的深入研究,ERCP将有新的发展前景。     

经内镜逆行胆胰管造影术在胆总管壶腹区病变中的诊疗价值

目的：探讨经内镜逆行胆胰管造影（ERCP）术在胆总管壶腹区病变中的诊疗价值。方法：回顾性分析23例胆总管病变的影像学资料。全部病例行超声波检查、ERCP检查；其中9例行多层螺旋CT检查，5例行MRCP检查。结果：ERCP术能较好的显示胆总管及其病变，且能对胆总管结石、慢性炎症狭窄进行微创治疗。结论：ERCP对胆总管病变的检查优于CT、MRCP，特别对十二指肠壁壶腹区的占位病变较CT、MRCP检查有不可替代的优越性和诊断价值。     

ERCP对胆总管疾病的诊疗价值

目的：探讨经内镜逆行胆胰管造影（ERCP）对胆总管疾病的诊疗价值。方法：回顾性分析108例胆总管疾病行胆胰管造影的影像学资料。全部病例行超声波、MRCP检查,52例行多层螺旋CT检查。结果：ERCP术能较好的显示胆总管及其病变,且能对胆总管结石、慢性炎症狭窄等疾病进行微创治疗。结论：ERCP对胆总管病变的检查优于CT、MRCP,特别对十二指肠壁壶腹区的占位病变具有明显的优越性和诊疗价值。     

ERCP、MRCP、CT对胰胆疾病诊断价值的对比研究

近年来,ERCP、MRCP及CT已广泛应用于胰胆疾病的诊断,为比较三种方法在诊断中的准确性及可靠程度,我们收集了我院自2004年12月至2006年12月份的92例患者的检查资料进行比较分析。     

ERCP在胆管疾病的诊断与治疗中的应用

目的探讨内镜逆行胰胆管造影对胆管梗阻疾病的诊断与治疗的价值。方法回顾性总结分析我院37例胆管疾病接受ERcP诊断与治疗的临床资料,比较分析与B超、CT、MRCP等影像学检查与ERcP诊断的准确性及ERCP对胆管疾病患者治疗的效果。结果ERCP对此疾病诊断的准确性明显高于B超、CT、MRCP等影像学检查,而且ERCP对胆总管结石、胆总管下段良性狭窄、胆管梗阻等治疗效果良好。结论ERCP对胆管疾病诊断与治疗有重要意义。     

磁共振胆胰管成像的临床应用

胆道和胰腺疾病的外科术前诊断以往需通过 B超、CT、PTC和 ERCP等手段完成。B超、CT不能整体显示胆树和胰管 ,有创伤性的 PTC和 ERCP虽可全面显示胆胰管解剖 ,但对有胆道梗阻和感染的病人 ,是一项危险的检查 ,磁共振胆胰管成像 (Mag-netic resonance cholangiopancreatography,MRCP)是近年来迅速发展并广泛应用于临床的一种非创伤性磁共振成像技术 ,不需要造影剂即可显示胆胰管系统 ,成像效果类似直接法胆胰管造影。由于 MRCP可多方位、多角度显示胆胰管 ,从而为胆道和胰腺疾病的治疗提供了丰富的影像学信息。1　MRCP成像原理…     

低场强MRCP与ERCP对胆胰疾病诊断的对比分析

目的探讨低场强磁共振胰胆管成像(MRCP)与内镜下逆行胰胆管造影术(ERCP)对胆胰疾病的诊断价值。方法对35例疑有胆胰疾病患者用重T2WI单次激发快速自旋回波序列(SSFSE)非屏气扫描技术不同角度的胰胆管成像。ERCP按常规方法进行。汇总双方诊断报告进行分析、比较。结果35例MRCP均获得成功,而ERCP成功率为(33/35)97.8%。MRCP和ERCP总的诊断准确率分别为91.4%和97.8%;其中对恶性狭窄的诊断准确率分别为75%和87.5%;对胆总管结石诊断的准确率分别94.4%和100%。结论良好的胃肠道准备和恰当的参数匹配低场强MRCP可作为胆胰疾病病因诊断的首选方法,但不能取代ERCP,两者结合可弥补各自的不足,提高诊断的准确性。     

低声强MRCP与ERCP对胆胰疾病诊断的对比分析

目的探讨低场强磁共振胰胆管成像(MRCP)与内镜下逆行胰胆管造影术(ERCP)对胆胰疾病的诊断价值.方法对35例疑有胆胰疾病患者用重T2WI单次激发快速自旋回波序列(SSFSE)非屏气扫描技术不同角度的胰胆管成像.ERCP按常规方法进行.汇总双方诊断报告进行分析、比较.结果 35例MRCP均获得成功,而ERCP成功率为(33/35)97.8%.MRCP和ERCP总的诊断准确率分别为91.4%和97.8%;其中对恶性狭窄的诊断准确率分别为75%和87.5%;对胆总管结石诊断的准确率分别94.4%和100%.结论良好的胃肠道准备和恰当的参数匹配低场强MRCP可作为胆胰疾病病因诊断的首选方法,但不能取代ERCP,两者结合可弥补各自的不足,提高诊断的准确性.     

Solid and liquid state characterization of tetrahydrocurcumin using XRPD,FT-IR,DSC, TGA,LC-MS,GC-MS,and NMR and its biological activities

Tetrahydrocurcumin (THC) is one of the major metabolites of curcumin (CUR), an ancient bioactive natural polyphenolic compound. This research article describes both the solid and liquid state characterization of THC using advanced spectroscopic and thermo-analytical techniques. Anti-inflammatory, anti-oxidant, and neuroprotective activities of THC were investigated using in vitro cell lines. Liquid chromatography-mass spectrometry analysis revealed that our sample comprised 95.15% THC, 0.51% tetrahydrodemethoxycurcumin (THDC), 3.40% hexahydrocurcumin, and 0.94% octahydrocurcumin. Gas chromatography-mass spectrometry analysis indicated the presence of 96.68% THC and 3.32% THDC. THC in solution existed as keto-enol tautomers in three different forms at different retention time, but the enol form was found to be dominant, which was also supported by nuclear magnetic resonance analysis. THC was thermally stable up to 335.55 °C. THC exhibited more suppression of cytokines (TNF-α, IL-1β, and MIP-1α) than CUR in a concentration-dependent manner in mouse splenocytes, while NK-cell and phagocytosis activity was increased in macrophages. THC showed a significant reduction of free radicals (LPO) along with improved antioxidant enzymes (SOD and catalase) and increased free radical scavenging activity against ABTS⁺ radicals in HepG2 cells. THC displayed higher protection capability than CUR from oxidative stress and neuronal damage by improving cell viability against H₂O₂ induced HepG2 cells and MPP⁺ induced SH-SY5Y cells, respectively, in a concentration-dependent manner. Thus, a variation of the biological activities of THC might rely on its keto-enol form and the presence of other THC analogs as impurities. The present study could be advantageous for further research on THC for better understanding its physicochemical properties and biological variation.     

蝌蚪中铜、锌、镁、铁、钙含量测定

目的 :探讨蝌蚪的化学成分。方法 :用火焰原子吸收分光光度法测定蝌蚪中无机元素的含量。结果 :蝌蚪中的无机元素铜、锌、镁、铁、钙的质量分数分别为 :0 .0 72mg·g-1、0 .12 4mg·g-1、3.316mg·g-1、5 .776mg·g-1和31.5 1mg·g-1。结论 :蝌蚪中无机元素钙的含量很高     

试从《伤寒论》干姜附子汤方证谈中医药学的理法方药与剂工质效

依据<伤寒论>干姜附子汤方证,初步探讨了中医学的理、法、方、药与中药学的剂、工、质、效.认为干姜附子汤方证反映了中医时间医学的精华,提示了症状排除法的诊断方法 ,树立了应用小方的典范,引导了后世"火神派"的形成,指引着中药药剂学的研究思路,鞭策着中药的质量管理模式及疗效.认真学习干姜附子汤方证,对于继承仲景之学,探讨中医药学系统工程的关键问题,推动中医药学术与事业的发展,都有重要意义.     

Database Application of Digital Medical X-rays and Labs: Computerization,Storage, Retrieval,Interpretation, and Distribution

Stenter lets the health care worker order an X-ray that is produced as a computer image rather than on flat film. The health care provider can be in any location with the correct equipment, and view the digital image. The dimensions of this discussion are extensive. The cost savings because of reduced media and storage cost is substantial. Health care quality can be improved because of the ability to obtain consultation via telemedicine and the enhanced ability to track medical problems over time via trends. The major downside is the limited cost imbursement system to pay for technology. Unfortunately, this may impact on the improved quality of care. In simple terms someone needs to pay for the technology and the quality of health care needs to be maintained or improved. The real cost to the health care systems needs to be correctly calculated and inappropriate charging kept to a minimum. Specific costs need to be kept in mind and the first is the cost for new staff or staff training. The number of health care providers that are able to read the X-ray can be enlarged remembering that only American Board Certified Radiologists are allowed to give the final recommendation. How do we view the cost of missing something? It could be argued that this risk will be reduced because of improved technology for obtaining the digital X-ray and improved enhancement software. One way to view this situation is to include technology, management, and organization. The cost and benefits occur through the interplay of all three dimensions. The development of digital imaging hardware and artificial intelligence software will demand change in the management and organization. The organization will require changes in its design to accommodate the technology as to support and resources. Management will evolve to include methods for control and monitoring this technology. Business processes and standard operating procedures will change to integrate the technology into the organization in the most effective and efficient manner.