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1.
Anon Chotirosniramit Akkaphod Liwattanakun Sunhawit Junrungsee Wasana Ko-iam Trichak Sandhu Worakitti Lapisatepun 《肝胆外科与营养》2020,9(6):729
BackgroundHepatocellular carcinoma (HCC) presenting with macroscopic bile duct tumor thrombus (BDTT) is an uncommon event. The role of a curative hepatic resection and associated long-term outcomes remain controversial. In addition the necessity for bile duct resection is still unclear. The aim of this study was to evaluate outcomes of hepatectomy with a selective bile duct preservation approach for HCC with BDTT in comparison to outcomes without BDTT.MethodsA total of 22 HCC with BDTT patients who had undergone curative hepatic resection with a selective bile duct preservation approach at our institute were retrospectively reviewed. These were compared to group of 145 HCC without BDTT patients. The impact of curative surgical resection and BDTT on clinical outcomes and survival after surgical resection were analyzed.ResultsAll HCC with BDTT cases underwent major hepatectomy vs. 32.4% in the comparative group. Bile duct preservation rate was 56.5%. The 1-, 3- and 5-year survival rates of HCC with BDTT patients in comparison to the HCC without BDTT group were 81.8%, 52.8% and 52.8% vs. 73.6%, 55.6% and 40.7% (P=0.804) respectively. Positive resection margin, tumor size ≥5 cm and AFP ≥200 IU/mL were significant risk factors regarding overall survival. However, it is unclear whether presence of a bile duct tumor thrombus has an adverse impact on either recurrence free survival or overall survival.ConclusionsBile duct obstruction from tumor thrombus did not necessarily indicate an advanced form of disease. Tumor size and AFP had greater impact on long-term outcomes than bile duct tumor thrombus. Major liver resection with a selective bile duct preserving approach in HCC with BDTT can achieve favorable outcomes comparable to those of HCC without BDTT in selected patients. 相似文献
2.
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目的探讨肝细胞癌(HCC)合并胆管癌栓外科治疗的效果。方法对1984年7月至2002年12月收治的53例HCC合并胆管癌栓的治疗情况进行回顾性总结和分析。结果53例中,1例未治,6例行经皮肝穿刺胆道引流(PTCD),46例开腹手术。开腹手术术后30d病死率为13.0%,并发症发生率为32.6%。肝切除术、胆管取癌栓及胆道引流术病人术后生存时间为5~46个月,中位生存期为23.5个月。结论黄疸不一定是肝癌的晚期表现,也不一定是手术禁忌证,对HCC合并胆管癌栓的早期诊断和手术治疗,是改善病人预后的关键。 相似文献
3.
肝门部胆管癌的外科治疗 总被引:2,自引:0,他引:2
目的 分析一个单位 1986-2 0 0 2年间治疗肝门部胆管癌的经验。方法 回顾 1986-2 0 0 2年在解放军总医院肝胆外科治疗 2 91例肝门部胆管癌的纪录 ,全部治疗均在单一的科室技术领导下进行 ,有一定的连贯性。外科治疗手段主要是依据手术中所发现的病理情况决定。根治性切除术的标准是指切除的边缘病理上未发现残留癌细胞者。结果 在我国 ,肝外胆管癌是并非少见的疾病 ,近年来手术治疗的病例数有增多倾向。然而 ,根治性切除手术有困难 ,甚至联合肝切除亦难以达到根治目的 ,因而根治性切除率只分别为 3 7.6%和 41.2 %。无切除术后 3 0d内死亡。有 4例病人于切除术后长期无瘤生存 ,5年以上生存率为 13 .3 % ;另有 2例病人亦生存达 5年以上 ,但癌复发 ,现仍在接受进一步治疗。结论 肝门部胆管癌是多态性的疾病 ,只是极少数表现为较“良性”的倾向 ,而绝大多数则于手术切除后易于复发 ,虽然手术似乎是已达治愈性。切除性治疗 ,甚至是姑息性切除 ,仍可以达到延长生命和提高生活质量的效果。扩大手术切除和淋巴结清扫范围的治疗作用尚未能确定 相似文献
4.
Toshimichi Nakayama Hideki Saitsu Jyunji Shibata Akira Hasuda Hisafumi Kinoshita Masafumi Yasunaga 《Journal of Hepato-Biliary-Pancreatic Surgery》1995,2(3):229-232
Hilar bile duct resection, by which only the bile duct is resected, was carried out in 31 patients with bile duct carcinoma
at the hepatic hilus. However, curative resection was possible in only 4 patients (12.9%). The postoperative 1-, 3-, and 5-year
survival rates were 58.1%, 19.4%, and 7.7%, respectively. These results indicate that treatment of this hilar bile duct carcinoma
by hilar bile duct resection is of limited value. We believe that this operative procedure should be used only for papillary
or nodular carcinoma at the hepatic confluence at relatively early stages of Bismuth's type I or II. 相似文献
5.
IntroductionWe report the first case of mass-forming intrahepatic cholangiocarcinoma (ICC) with portal vein tumor thrombus (PVTT) and bile duct tumor thrombus (BDTT), where the extrahepatic bile duct was preserved with thrombectomy.Presentation of caseA 70-year-old male. Magnetic resonance imaging (MRI) showed the tumor extending from the hepatic hilum to the left hepatic duct with complete obstruction of the left hepatic duct and a defect at the left portal vein. We planned to perform extended left lobectomy, lymph node dissection, extra hepatic bile duct resection and reconstruction based on the diagnosis of mass-forming ICC with left portal vein and left hepatic duct infiltration (cT3N0M0 Stage III). Intraoperative cholangiography revealed a crab claw-like filling defect at the left hepatic duct, which suggested tumor thrombus. Accordingly, we performed thrombectomy. The margin of the left hepatic duct was tumor negative, so we performed extended left lobectomy, lymph node dissection and thrombectomy. Pathologically, the tumor was diagnosed as ICC (pT4N0M0 Stage IVA, vp3, b3). Tumors in the left hepatic duct and left portal vein proved to be tumor thrombus. The postoperative course was uneventful. He is doing well without recurrence.DiscussionThrombectomy is performed for hepatocellular carcinoma (HCC) with tumor thrombus. Furthermore, extrahepatic bile duct resection and reconstruction are recommended for ICC. In this case, intraoperative cholangiography was effective for precisely diagnosing. Thrombectomy could reduce surgical stress and prevent complications.ConclusionsThrombectomy can be a valid option for ICC with tumor thrombus, as well as for HCC. 相似文献
6.
Kinoshita H Nagashima J Hashimoto M Nishimura K Kodama T Matsuo H Hamada S Yasunaga M Odo M Fukuda S Hara M Okuda K Hiraki M Shirouzu K Aoyagi S 《Journal of Hepato-Biliary-Pancreatic Surgery》2004,11(1):64-68
We report a patient with benign bile duct stricture causing difficulty in differential diagnosis from bile duct carcinoma. A 66-year-old woman consulted a local physician because of general fatigue. Blood biochemical tests showed increased levels of biliary tract enzymes. Abdominal ultrasonography (US) revealed tapering and blockage of the midportion of the bile duct and dilation of the intrahepatic bile ducts. Magnetic resonance cholangiopancreatography (MRCP) demonstrated obstruction of the midportion of the bile duct. Later, because a marked increase in biliary tract enzymes and jaundice appeared, percutaneous transhepatic biliary drainage (PTBD) was performed. Post-PTBD cytological examination of bile was negative for cancer. A third biopsy showed slight hyperplasia with no malignant findings. Recholangiography, performed through PTBD, suggested gradual improvement of bile duct stricture, but could not completely exclude the possibility of malignancy; thus, resection of the bile duct including the stricture site was performed, and the resected specimen was submitted for intraoperative frozen section examination. Histopathological diagnosis did not reveal malignant findings. After cholecystectomy and bile duct resection, hepaticojejunostomy (Roux-en-Y) was performed. Because only erosion and desquamation of the mucosal epithelium and mild submucosal inflammatory cell infiltration and fibrosis were observed, chronic cholangitis was diagnosed histopathologically. Surgical resection of the bile duct should be considered for potentially malignant stricture of the bile duct. 相似文献
7.
Hiromu Tanaka Kazuhiro Hirohashi Yasuhiro Ohta Eiji Kimura Taichi Shuto Akishige Kanazawa Takatsugu Yamamoto Hiroaki Kinoshita 《Journal of Hepato-Biliary-Pancreatic Surgery》1995,2(4):451-456
Hilar bile duct carcinoma has a poor prognosis, but this has been improved in recent years by an aggressive surgical approach.
We treated a 73-year-old woman who had obstructive jaundice due to bile duct carcinoma at the hepatic hilum. The jaundice
decreased after percutaneous transhepatic biliary drainage. The tumor was resected with the left and caudate lobe of the liver
and a part of portal vein. The right hepatic artery was located behind the common hepatic duct, and was suspected to be invaded
by the tumor. We dissected the tumor from the arterial wall without carrying out combined resection of the hepatic artery.
On the 6th postoperative day, the hepatic artery ruptured and the patient suffered hypovolemic shock. Resection of the hepatic
artery and reconstruction were done, but the patient died 2 days later. Histological examination of the resected artery showed
that the tumor had been curatively removed by dissection and that no tumor remained at the arterial wall. The rupture of the
right hepatic artery was thought to have been caused by damage to the wall during the dissection procedure. 相似文献
8.
Junya Yamamoto Yuji Abe Kazuyoshi Nishihara Fujio Katsumoto Shigeaki Takeda Ryuji Abe Satoshi Toyoshima 《Surgery today》1998,28(7):758-762
4 , S5) and bile duct resection with lymphnode dissection were performed. A tumor measuring 6.0 3 3.0 cm was found to be located
in the bile duct of the hepatic hilus. Histologically, the tumor was composed of well-differentiated adenocarcinoma and small
cell neuroendocrine carcinoma cells, with a histological transition between the two components. Grimelius' method revealed
the presence of diffuse positive tumor cells in neuroendocrine carcinoma. The neuroendocrine tumor cells were also diffusely
immunoreactive to chromogranin A. To the best of our knowledge, only 22 previous cases of composite glandular-neuroendocrine
carcinoma in the biliary tract have been reported; however, this is the first case report of a clearly composite tumor of
the hilar bile duct.
(Received for publication on Aug. 19, 1996; accepted on May 12, 1997) 相似文献
9.
目的分析肝细胞癌(HCC)合并肝门部胆管癌栓(HBDTT)的CT影像特征,并探讨其与肝门部胆管癌(hilar CC)的CT鉴别诊断。方法收集中山大学附属第一医院及江门市新会中医院2013年1月至2018年12月经病理证实的HCC伴HBDTT患者42例(HBDTT组)及hilar CC患者51例(hilar CC组),对两组患者的临床资料及CT影像表现进行比较和分析。结果与hilar CC组相比,HBDTT组男性、乙型肝炎病史、上腹部疼痛比例较高,甲胎蛋白(AFP)水平升高更为常见,而hilar CC组CA19-9、癌胚抗原(CEA)升高患者更多(均P<0.05)。两组CT征象在是否同时累及肝实质及胆管、门静脉期“快退”、胆管壁增厚、血管癌栓及脾大等方面差异均有统计学意义(P<0.001),5项征象均具有较高的特异度(82.4%~98.0%),其中前3项诊断敏感度较高(100.0%、92.9%、85.7%)。结论利用CT可以对HCC合并HBDTT与hilar CC作出准确的鉴别诊断。病变同时累及肝实质和肝门部胆管、门静脉期“快退”及胆管壁不增厚是HCC伴HBDTT的特征性征象,结合乙型肝炎病毒感染、AFP水平升高等综合分析对鉴别HCC伴HBDTT与hilar CC有重要作用。 相似文献
10.
Hai S Yamamoto S Tanaka H Takemura S Ichikawa T Kodai S Shinkawa H Yamamoto T Kubo S 《Surgery today》2007,37(7):608-611
We report an unusual case of adenomyoma of the common hepatic duct mimicking bile duct cancer. A 50-year-old woman was referred
to our hospital for the investigation of general fatigue. Laboratory data showed abnormal liver test results and computed
tomography showed a mass lesion in the hepatic hilum and dilatation of the intrahepatic bile ducts. These findings led to
a preoperative diagnosis of hilar bile duct carcinoma, and we performed a left lobectomy with resection of the extrahepatic
bile duct. Macroscopically, an elevated lesion was found in the common hepatic duct, which was confirmed histologically to
be an adenomyoma. Bile duct strictures are rarely caused by benign tumors of the biliary tract, such as adenomyoma. Surgical
resection of the bile duct should be considered for all bile duct strictures because it is often difficult to differentiate
malignant from benign lesions in this location preoperatively, and malignant cells may be present in the lesion. 相似文献
11.
One hundred and eleven liver resections for hilar bile duct cancer 总被引:22,自引:5,他引:17
Lee SG Lee YJ Park KM Hwang S Min PC 《Journal of Hepato-Biliary-Pancreatic Surgery》2000,7(2):135-141
A positive correlation between absence of residual tumor at resection margins and long-term survival in the treatment of
hilar bile duct carcinoma has encouraged some surgeons to use a more radical approach, including liver/portal vein resection
and combined pancreatoduodenectomy. However, if liver resection is associated with significant morbidity and mortality, it
may not produce any overall benefit. This review was undertaken in an attempt to determine whether liver resection is a safe
procedure and whether if has any beneficial effect over that of local bile duct excision alone, in terms of achieving curative
resection and long-term survival. The records of 151 patients with hilar bile duct carcinoma surgically treated between June
1989 and December 1997 at the Asan Medical Center, Seoul, were retrospectively analyzed. Surgical resection was possible in
128 patients. The remaining 23 patients had surgical palliative drainage. Local bile duct excision alone was performed in
17 patients. Liver resection for tumor extending to secondary bile ducts or hepatic parenchyma was performed in 111 patients;
portal vein resection was necessary in 29 of these 111 patients (26.1%) and pancreatoduodenectomy was combined in 18 patients
(16.2%). Seven patients died during hospitalization after liver resection, an operative mortality of 6.3%. Margins of bile
duct resection were free of tumor on histologic examination in 4 of the 17 local bile duct excisions, but in 86 of the 111
liver resections. The cumulative survival rate after local bile duct excision was 85.7% at 1 year, 42.9% at 2 years, 21.4%
at 3 years, and 0% at 4 years. However, the survival rate after liver resection (excluding operative mortality) was 97.1%
at 1 year, 72.8% at 2 years, 55.3% at 3 years, and 24.0% at 5 years. Survival and the percentage of patients with tumor-free
resection margins after liver resection were superior to those after local bile duct excision. Resection of hilar bile duct
carcinoma offers long-term survival only when surgery is aggressive and includes liver resection.
Received for publication on July 2, 1998; accepted on July 5, 1998 相似文献
12.
Abe T Kajiyama K Harimoto N Gion T Shirabe K Nagaie T 《International journal of surgery case reports》2012,3(7):275-278
INTRODUCTIONInvasion of the portal and hepatic veins by hepatocellular carcinoma (HCC) is common, but macroscopic bile duct invasion is rare. Once a tumor thrombus completely obstructs the main bile duct, it causes obstructive jaundice. This type of HCC, known as icteric-type HCC (IHCC), has a poor prognosis.PRESENTATION OF CASEA 72-year-old woman had been treated for chronic hepatitis C since 1997. In 2002, percutaneous ethanol injection therapy was performed for HCC in segment 8. HCC recurrence occurred in 2004, and she underwent transarterial embolization (TAE) and radiofrequency ablation (RFA). In 2006, an S8 segmentectomy was performed for re-recurrence of HCC. Three years after surgery, computed tomography (CT) revealed a tumor occupying the right anterior intrahepatic bile duct and extending into its right main branch. With a preoperative diagnosis of HCC recurrence in the bile duct, we performed a right hepatectomy and thrombectomy. Histological examination showed moderately to poorly differentiated HCC. No tumor tissue other than the intrahepatic bile duct tumor was detected in the resected liver specimen.DISCUSSIONHCC with biliary tumor thrombus is associated with a poor prognosis. In general, IHCC is difficult to diagnose and treat in the early stages. A characteristic radiological finding for this type of IHCC is the hypervascularity of the tumor thrombus.CONCLUSIONTo the best of our knowledge, this is a rare case of IHCC recurrence as a tumor thrombus without recurrence in the resected liver specimen. 相似文献
13.
IntroductionMixed adenoneuroendocrine carcinomas (MANECs) derived from cystic duct are extremely rare.Presentation of caseAn 80-year-old woman was admitted to the department of surgery, Onomichi general hospital with abnormal liver function and jaundice. Enhanced abdominal computed tomography (CT) detected a well-enhanced papillary tumor in the cystic duct, which protruded into the common bile duct. The intrahepatic bile duct was dilated due to tumor obstruction. The entire tumor showed high intensity in T2-weighted magnetic resonance imaging (MRI) imaging. Endoscopic retrograde cholangiopancreatography (ERCP) showed that the tumor ranged from part of communication of three ducts (cystic, common hepatic and common bile duct), to the middle of common bile duct. Biliary cytology determined a class V malignancy (adenocarcinoma). Endoscopic ultrasound determined that the tumor was primarily at the cystic duct with heterogeneous echoic pattern, which extended into the common bile duct. The preoperative diagnosis was cystic duct carcinoma (T3N0M0, StageIIIA). An extended cholecystectomy with regional lymph nodes dissection was performed. Histologically, the tumor had components of both well-differentiated tubular adenocarcinoma and neuroendocrine carcinoma, which is classified as MANECs according to the 2010 WHO classification of endocrine tumors. Eight months after surgery, multiple liver metastases were discovered, and treatment with adjuvant chemotherapy was initiated.DisscusionWe present a rare case of MANECs derived from cystic duct. Until now, an established adjuvant systemic chemotherapy has not emerged, and curative resection, with poor long-term prognosis, remains the only treatment option.ConclusionThough standards of treatment for MANECs have not been established,multidisciplinary theraphy is necessary to improve outcome. 相似文献
14.
G. Froeschle U. Meyer-Pannwitt R. Schwarz C. Werner B. Kremer 《Journal of Hepato-Biliary-Pancreatic Surgery》1994,1(3):285-288
This report concerns three cases of bile duct carcinoma which occurred 15–40 years after patients received treatment for urogenital
neoplasia. All three patients had initially received radiation therapy in addition to urological surgery. Jaundice was the
major clinical symptom of the second tumor. Two of the three patients were able to be surgically treated when presenting with
their second carcinoma (partial pancreaticoduodenectomy, bile duct resection; central liver resection), whereas the third
patient was in such a poor state of health that he was biopsied only and treated with a pigtail drain. All three patients
died within 3 months to 3 years following the diagnosis of the second tumor. The more than coincidential occurrence of the
rare bile duct carcinoma in our three patients with previous urogenital neoplasia warrants a new discussion concerning the
connection between primary carcinoma, radiation therapy, and the occurrence of a second tumor. 相似文献
15.
Records of 25 consecutive patients who underwent resection for proximal bile duct tumor (3 extended right hepatic lobectomies,
6 left hepatic lobectomies, 16 skeletonization resections) and records of 21 patients who underwent pancreatoduodenectomy
for distal bile duct carcinoma were reviewed to assess the value of resective therapy. The operative mortality rate for patients
with resected proximal bile duct tumor was 4 per cent (0 per cent for liver resection) and that of distal bile duct tumor,
4.6 per cent. The 3- and 5-year actuarial survival rates for patients with proximal bile duct tumor were 44 per cent and 35
per cent, respectively; all except one patient eventually died of disease. Survival was better for patients who had curative
resection (margins microscopically free of tumor). The 5-year actuarial survival rate for patients with distal bile duct carcinoma
was 58±12 (SE) per cent, with patients who had negative nodes surviving longer than patients with positive nodes. When major
hepatic resection and pancreatoduodenectomy can be performed in selected patients with low operative mortality, patients with
bile duct carcinoma should be assessed by an experienced hepatobiliary multidisciplinary group before a decision is made in
favor of palliative, endoscopic, or percutaneous techniques because surgical resection appears to offer the best possible
long-term survival and probably the best quality of palliation.
This report is the basis of a paper read by R.L.R. at the 90th Annual Meeting of the Japanese Surgical Society, Sapporo, Japan,
1990 相似文献
16.
原发性肝癌伴胆管癌栓导致阻塞性黄疸的诊治 总被引:2,自引:0,他引:2
目的;探讨原发性肝癌继发胆管癌栓引起阻塞性黄疸(阻黄)的临床表现,诊断,治疗及手术方式与预后的关系。方法:回顾分析我院收治的11例阻黄患者的临床资料。结果:患者的临床症状不典型,入院后按常规均行化验及B超,CT、ERCP,MRCP,PTC等检查,并分别行肝原发癌灶切除,胆管癌栓清除,T管引流,肝动脉插管埋泵等手术治疗,术前诊断符合率为45.5%。术后对症化疗,患者预后与术式有关,行切除肝内原发肿瘤 胆道癌栓清除术者预后较好,行单纯癌栓清除术者预后较差。结论:原发性肝癌继发胆管癌栓引起阻黄术前不易诊断,应选择多种检查手段。包括术中B超,纤维胆道镜等检查,力求确诊,尽可能切除原发性肝内癌灶以提高疗效。 相似文献
17.
Yukio Sonoda Koji Yamaguchi Eishi Nagai Makoto Nakamuta Tetsuhide Ito Takashi Eguchi Kazuo Chijiiwa Masao Tanaka M.D. 《Journal of gastrointestinal surgery》2003,7(5):631-634
Small cell carcinoma usually involves the lung and rarely affects the biliary tract, especially the cystic duct. In this article
we report a case of small cell carcinoma of the cystic duct in a 46-year-old Japanese man. The patient presented with abdominal
pain and jaundice. Imaging showed a small nodule in the cystic duct invading the common bile duct with dilatation of the proximal
biliary tree. The hepatic artery and portal vein were free from invasion. Extended right hepatic lobectomy, cholecystectomy,
and resection of the extrahepatic proximal bile ducts were performed together with lymph node dissection under the tentative
diagnosis of carcinoma of the cystic duct. Histopathologic examination of the resected specimen revealed small cell carcinoma
arising in the cystic duct and extending into the common bile duct. The postoperative clinical course was uneventful, and
the patient is doing well without any signs of recurrence 1 year after the operation. To our knowledge this is the first documented
case of a small cell carcinoma arising in the cystic duct. 相似文献
18.
Shima Y Horimi T Shibuya Y Sakurama K Nishie M Morita S 《Journal of Hepato-Biliary-Pancreatic Surgery》2004,11(6):438-440
Biliary cystadenoma in the extrahepatic bile ducts is a very rare tumor. A 62-year-old woman with jaundice was admitted to our hospital. Imaging studies revealed a 4-cm cystic lesion around the hepatic hilum, compressing the common bile duct (CBD). When laparotomy was performed, a cystic tumor was detected in the hepatic hilum, filling the lumen of the CBD. Bile duct resection that included the tumor was performed, followed by biliary reconstruction. Microscopically, the cyst wall was lined by a single layer of cuboidal epithelial cells, covering an ovarian-like stroma. The degree of atypia was low and warranted the diagnosis of cystadenoma. 相似文献
19.
Satoh S Ikai I Honda G Okabe H Takeyama O Yamamoto Y Yamamoto N Iimuro Y Shimahara Y Yamaoka Y 《Surgery》2000,128(5):779-783
BACKGROUND: The aim of this study was to evaluate the clinicopathologic characteristics of patients with hepatocellular carcinoma (HCC) and bile duct thrombi (BDT). PATIENTS: Seventeen patients with HCC and BDT among 671 patients with HCC who underwent hepatic resection were enrolled in this study. RESULTS: There were no significant differences in the survival rates between patients with and those without BDT, although the rate of stage IV or portal vein invasion was significantly higher in patients with HCC and BDT than in those with HCC but without BDT. In 9 of 17 patients with BDT, preoperative jaundice was observed. Five of the 17 patients underwent a bile duct resection combined with hepatic resection, and 12 patients underwent hepatic resection with removal of the BDT without bile duct resection. None of the patients had histopathologic evidence of direct tumor invasion into the bile duct wall or of any tumor recurrence related to the BDT. There were no significant differences in the survival rates between patients who underwent bile duct resection and those who did not. CONCLUSION: Hepatic resection and the removal of BDT without bile duct resection were sufficient surgical interventions to treat patients with HCC and BDT. 相似文献
20.
To determine the benefits of surgical treatment for patients with carcinoma of the extrahepatic bile duct, data on 100 patients
with this disease who had been surgically treated in our clinic during the past 18 years were evaluated. These patients were
grouped into three, i.e., upper, middle and lower bile duct groups. Patients with periampullary tumor were excluded from this
study. Surgical procedures consisted of resection of the tumor, including hepatic resection and dissection of the regional
lymph nodes, and a bypass operation of the extra- or intrahepatic bile duct. Resectability rates of the tumor were 21.6% in
upper, 82.4% in middle, and 50% in lower bile duct groups. Average survival times of patients who had a resection of the tumor
were 30.3 months in the upper bile duct group, 35.9 months in middle (the longest, 13 years and 3 months) and 22.5 months
in lower bile duct group. Survival rates of overall patients with resection of tumors were 64.5% at one year, 29.0% at 3 years,
and 12.9% at 5 years after surgery, respectively. The middle bile duct group showed the most favorable operative results of
all the groups, an extended resection of the tumor should be carried out to obtain for a longer survival. 相似文献