新型冠状病毒肺炎疫情下妇幼保健机构的应急管控策略和措施

孕产妇和儿童是新型冠状病毒肺炎(novel coronavirus pneumonia,NCP,简称新冠肺炎)的易感人群,疫情期间我院从儿童、孕产妇入院就诊管理、住院防控管理、医护人员专业技能、诊疗服务模式、健康宣教等五个方面制订了针对性的应急管控策略和措施,有力保障了就医群众及医院职工的健康安全.     

新型冠状病毒肺炎诊治

2019年12月在武汉市爆发新型冠状病毒肺炎新型冠状病毒肺炎(COVID-19)中国引起严重疫情并在世界多个国家引起疫情,疫情来势凶猛及传染性强。我们对引起此次疫情的病原体-2019新型冠状病毒知之甚少,我们在此结合近期在新冠肺炎方面发表相关的研究,介绍新冠肺炎的诊断与治疗体会。     

新冠疫情期间定点医疗机构内住院结核病患者对新冠肺炎的风险感知及情绪反应

目的探讨新冠疫情期间定点医疗机构内住院结核病患者,对新冠肺炎的风险感知情绪反应。方法采取便利抽样法选取某传染病专科医院183例肺结核住院患者,于入院期间采用一般资料、新冠疫情风险感知问卷进行调查,对问卷结果进行统计分析。结果共发放183份问卷,回收有效问卷179份,有效回收率为97.81%。疫情期间结核病住院患者对新冠肺炎传播途径、易感人群、预防措施、佩戴何种口罩认知率分别为75.6%、81.8%、81.0%和83.0%。35.8%的调查对象对于目前发生的新冠肺炎疫情感觉焦虑,29.1%感觉紧张。疫情发生后,97.2%的调查对象外出时带防护物品,91.6%强化个人卫生,84.4%减少与他人接触机会。新冠疫情知识获得途径主要是电视和广播,人群最关注的信息是政府防控措施(64.8%)和疫情蔓延程度(62.0%)。结论新冠疫情期间,定点医疗机构内住院结核病患者,能掌握部分新冠肺炎相关知识,但掌握不全;疫情下,患者存在焦虑、紧张等情绪,提示我们当下更需要准确的通过多种途径,多种宣传手段,及时有效将疾病相关知识信息传递给患者,引导患者正确认识疾病,积极应对与防控。     

新型冠状病毒肺炎疫情期间上海基层医务人员心理健康状况及影响因素分析

目的 ：了解上海基层医务工作者在新型冠状病毒（新冠）肺炎疫情期间的心理状况,并分析影响因素,为后续干预及处理提供科学依据。方法：根据新冠肺炎疫情期间上海基层医务工作者相关工作情况自行设计调查问卷。于2023年1—2月对上海基层医疗机构的在职医务工作者进行问卷调查,收集个人基本信息,明确疫情期间基层医务工作者的心理健康状况,并分析其影响因素。结果：患有抑郁、焦虑症状分别为72.0%、57.6%。工作-家庭冲突情况与抑郁（r=0.391,P<0.05）、焦虑（r=0.370,P<0.05）情况呈正相关。大专及以下学历、年收入较疫情前减少11%～30%、护士、既往参加过公共卫生突发事件、工作压力与工作强度较大、薪酬满意度较小的医务工作者工作-家庭冲突总分较高（均P<0.05）;女性、年龄30～39岁、大专及以下学历、中级职称、工作年限<10年、护士、既往参加过疫情相关公共卫生突发事件、工作压力与工作强度较大、薪酬满意度较小的医务工作者抑郁、焦虑量表得分较高。结论：新冠肺炎疫情对上海基层医务人员的心理健康状况产生了一定程度的负面影响,提高薪资待遇、采取心理咨询和辅导、合...     

新型冠状病毒肺炎疫情对湖南省血吸虫病防控影响的调查及对策分析

目的 分析新时期血防工作所面临的难点和挑战,探讨本次新冠疫情后血防工作中应优先关注或加强的方向,并对今后血防工作重点提出建议,为推动湖南省血吸虫病消除进程提供决策依据和技术支撑。 方法 根据新型冠状病毒肺炎疫情形势下湖南省血吸虫病防治工作的实际情况和消除目标任务,分阶段对 16 个血防任务及新冠疫情均较重的县(区)以问卷调查、访谈和视频会议等方式开展调查,分析新冠肺炎疫情对血吸虫病防治相关工作的短期与长期影响。 结果 在新冠肺炎疫情应急式防控期间,调查地区所有血防机构均参与新冠疫情防控工作,对血防工作产生了明显的短期影响,并以人群血吸虫病查治病、健康教育和疫情监测 3 项工作受影响最为突出(计划完成率各项指标均<20%)。 在疫情防控常态化期间,延后的工作计划大部分得以弥补完成,大多数被调查者认为血吸虫病防治的任务目标和执行力不会改变,血防经费不会削减,到年底任务预计依然能顺利完成。 结论新型冠状病毒肺炎疫情对湖南省血吸虫病防控工作产生了明显的短期影响。 血吸虫病防控工作者应以新冠肺炎疫情防控为鉴,努力提高应对重大突发公共卫生事件的能力和水平,加强监测预警能力体系建设。     

新型冠状病毒疫情期间精神病院护士心理健康状况及睡眠质量调查分析

目的探讨新冠肺炎疫情期间精神病院一线护士的心理健康状况、睡眠质量及相应的整改措施。方法采用整群随机抽样方法,抽取广西2家规模较大的精神专科医院一线护士92名作为调查对象。采用症状自评量表(SCL-90)、抑郁自评量表(SDS)、焦虑自评量表(SAS)及匹兹堡睡眠质量指数量表(PSQI),在新冠肺炎疫情期间对他们进行网络问卷调查。结果精神病院一线护士的SCL-90总分、躯体化、抑郁、焦虑、恐怖等因子分均高于我国常模,差异有统计学意义(P0.05);心理健康异常者占26.09%;抑郁检出率为48.91%,焦虑检出率为56.52%;睡眠质量出现问题者占75.0%。结论新冠肺炎疫情期间,精神病院一线护士的心理健康状况和睡眠质量都比较差,容易出现抑郁、焦虑情绪,严重影响睡眠质量。医院应采取心理干预、改善工作环境、减轻工作压力等综合措施来改善护士的心理健康状况和睡眠质量,从而保证护理质量,共同抗击新冠肺炎。     

某养老机构新型冠状病毒肺炎聚集性疫情流行病学特征分析

目的对某养老机构发生一起新型冠状病毒肺炎(COVID-19)聚集性疫情进行回顾性流行病学调查和分析。方法采用"新型冠状病毒肺炎防控方案(第三版)"推荐的个案调查表和依照"新型冠状病毒肺炎聚集性疫情流行病学调查指南(试行第一版)"进行。结果某养老机构有8名护理人员和住院老人感染新冠肺炎,年龄中位为59岁,男、女比例1∶7。于末次暴露后4~15 d确诊。排查出225名密切接触者,无三代院内续发传播;不排除无症状感染存在传染的可能性;病亡1例。结论本次聚集性疫情的感染来源于新冠肺炎确诊病例。建议防控策略应关注养老机构、监管场所等重点部门、重点人群的管控与监测。     

新型冠状病毒Delta变异株感染患者早期实验室检查指标变化及疫苗保护作用观察

目的 观察新型冠状病毒(新冠病毒)Delta变异株感染患者外周血早期实验室检查指标及疫苗接种对新冠病毒Delta变异株感染患者的保护作用,为疫情防控提供参考.方法 2021年11月成都本土疫情中诊断为新冠病毒Delta变异株感染的年龄>18岁的新型冠状病毒肺炎(新冠肺炎)非重型患者25例,记为实验组,22例在感染前接种...     

警惕新型冠状病毒感染后的心脏与神经损害，传统药物及中草药防治有效吗?

<正>新型冠状病毒(新冠病毒)从上呼吸道侵入造成呼吸道损害和炎症反应,通常易引起重视。各类病毒性感染,常常因病毒突破皮肤黏膜屏障进入血循环而演变为系统性感染,新冠病毒感染也不例外,重症住院患者出现包括心血管在内的多系统损害亦十分常见。笔者注意到2022年冬季新型冠状病毒感染疫情(新冠疫情)暴发流行中,许多轻症患者感染后出现不同程度的活动时心慌、气促或出现胸闷、心前区疼痛等症状,     

宿州市新冠肺炎疫情不同防控阶段核酸检测结果分析

目的 在新冠肺炎疫情不同阶段采取不同核酸检测策略,比较新冠病毒核酸检测结果差异,为调整防控措施提供科学依据。 方法 2020 年 1 月 22 日—2 月 29 日采集宿州市重点人群的咽拭子和痰液样本,利用实时荧光RT-PCR 法检测新型冠状病毒核酸,比较不同防控阶段新冠病毒核酸检测结果差异。 结果 采集重点人群 704 人的 1 182 份样本,其中 46 人的 59 份样本检测出新冠病毒核酸,样本阳性检出率 4. 99%(59 / 1 182),最终确诊 41 例新冠肺炎病例、5 例无症状感染者。 新冠病毒核酸样本阳性检出率最高阶段为疫情初期,高达 14. 81%(12 / 81),其次是第二阶段(6. 17%,24 / 389)和第三阶段(5. 71%,22 / 385),最低为第四阶段(0. 31%,1 / 327)。 样本阳性检出率最高人群为有湖北省旅居史人员,为 10. 13%(31 / 306),其次是密切接触者 3. 85%(28 / 727),本地发热门诊留观患者中未检出阳性。 结论 宿州市在新冠肺炎疫情发展不同阶段及时调整核酸检测策略,为有效控制疫情的发展提供强有力的保障;在加强对中高风险地区人员、密切接触者等重点人群检测时,应尽可能增加样本采集次数,减少漏检。     

Racial differences in preventive practices of African-American and Hispanic women

OBJECTIVES: To compare the use of preventive practices of Hispanic- and African-American women aged 50 and older. DESIGN: A cross-sectional survey. SETTING: Inpatient and outpatient units of a teaching hospital located in South Central Los Angeles. PARTICIPANTS: Convenience sample of 337 women aged 50 and older. MEASUREMENTS: Demographic and lifestyle characteristics and selected preventive practices. Preventive practices reported were self-breast examination, mammography, Papanicolaou (Pap) smear, digital rectal examination and stool occult blood examination, sigmoidoscopy, chemoprophylaxis, and immunization. Information was obtained in a face-to-face interview. RESULTS: African-American women were more likely to have had a Pap smear ever and to have used aspirin prophylaxis than Hispanic women. CONCLUSION: There were no major differences in the use of preventive services by the two ethnic groups except for Pap smear and aspirin use. Immunization and colorectal cancer screening rates were low in African-American and Hispanic women.     

African American Women,AIDS, and Resiliency

ABSTRACT

Ongoing shifts in the populations affected by the AIDS epidemic are reflected in the increasing proportion of AIDS cases in women-particularly women of color. While African American women represent approximately 13% of the U.S. female population, in 2000, 63% of all reported AIDS cases in women in the United States were among African American/non-Hispanic women. Despite these statistics, relatively few studies in the area of HIV research target African American women exclusively. As part of a larger study, we asked 105 African American women to describe in their own words how their lives have changed since becoming HIV positive. Despite multiple past and current stressors, the majority of participants provided responses that were decidedly positive. Clinical implications as well as future research directions based on these findings are discussed.     

2009年吉林省农村地区孕妇和哺乳期妇女碘营养状况与甲状腺功能调查

目的 调查吉林省农村地区孕妇和哺乳期妇女的碘营养水平及甲状腺功能状态.方法 2009年选择吉林省磐石市宝山、明城、烟筒山3个乡的农村作为调查地区,抽取当地孕妇和哺乳期妇女作为观察对象,收集血样,直接化学发光免疫分析法检测甲状腺功能[总、游离三碘甲腺原氨酸(TT3、FT3),总、游离甲状腺激素(TT4、FT4)],放射免疫分析法检测甲状腺球蛋白抗体(TgAb)、甲状腺微粒体抗体(TMAb)、甲状腺球蛋白(Tg);1个月内连续3次采集观察对象尿样,砷铈催化分光光度法检测尿碘.结果 被调查对象中TT3高于正常的孕妇占14.3%(8/56),而TT4、FT3、FT4低于正常的孕妇分别占3.6%(2/56)、5.4%(3/56)、1.8%(1/56);TT3高于正常的哺乳期妇女占3.6%(2/56),TT4、FT4低于正常的哺乳期妇女各占1.8%(1/56).有5%～20%的孕妇和哺乳期妇女TgAb、TMAb升高.孕妇和哺乳期妇女尿碘中位数3次检测结果分别为193.35、170.80、197.30 μg/L和193.00、225.85、262.90μg/L.结论 现行盐碘水平对孕妇和哺乳期妇女是适宜的,部分孕妇存在甲状腺功能减退倾向,应对孕妇和哺乳期妇女开展常规尿碘及甲状腺功能监测.

Abstract：

Objective To investigate the iodine nutritional level and thyroid function of pregnant and lactating women in rural areas of Jilin province. Methods The investigation sites were selected from rural areas of three towns (Baoshan, Mingcheng and Yantongshan of Panshi county, Jilin province) in 2009. The pregnant and lactating women were selected as subjects in these three towns. The blood samples were collected and the thyroid function (including serum TT3, TT4, FT3, FT4) were measured with chemiluminescence, and serum thyroglobulin antibodies(TgAb), thyromicrosome antibody(TMAb), and thyroglobulin(Tg) were measured with radioimmunoassay (RIA). The urine samples were collected three times within one month and were measured for iodine concentration by As-Ce catalytic spectrophotometry method. Results In the pregnant women, serum TT3 was higher than that of healthy pregnant women, accounted for 14.3%(8/56), while serum TT4, TT3, FT4 were lower than those of healthy pregnant women, accounted for 3.6%(2/56),5.4% (3/56), and 1.8%(1/56), respectively. In the lactating women,serum TT3 was higher than that of healthy lactating women, accounted for 3.6%(2/56), while serum TT4, FT4 were lower than those of healthy lactating women, accounted for 1.8%(1/56), respectively. Five per cent to 20% of the pregnant and lactating women had higher TgAb and TMAb. Conclusions Existing salt iodine level is appropriate for pregnant women and lactating women, but there was a tendency towards hypothyroid in some women. Routine monitoring of urinary iodine and thyroid function should be carried out among pregnant and lactating women.     

2011年哈尔滨市不同人群碘营养状况调查

目的 调查及评价哈尔滨市不同人群的碘营养状况,为制定食盐加碘标准和科学补碘提供依据.方法 2011年,在哈尔滨市的3个区和周边的3个县(市),各选择1个街道办事处(乡、镇),每个街道办事处(乡、镇)各选1个居委会(村),用系统抽样方法各抽取30户居民,分别检测家中碘盐、水碘和人均摄碘量.在每个抽中居委会(村)的居民户中,各抽取18 ～45岁成人20名；在每个被抽中的街道办事处(乡、镇),各选择孕妇、哺乳期妇女30名和8～ 10岁在校儿童100名,采集尿样,检测尿碘含量.根据调查结果,分析城区和农村的不同人群摄碘情况和碘营养情况,评估哈尔滨市居民的碘营养状况是否适宜.盐碘测定采用直接滴定法,水碘、尿碘测定采用砷铈催化分光光度测定方法.结果 哈尔滨市城区和农村居民合格碘盐食用率分别为93.3％( 84/90)和96.3％(156/162),均＞90％;盐碘最高值分别为38.3、46.0 mg/kg,均未超过合格碘盐上限(50mg/kg),但有部分样品盐碘含量低于国家标准(20 mg/kg);从城区和农村水碘看,即便是最高值(9.40、8.40 μg/L)也未达到10 μg/L 的标准.农村每人、每天吃盐8.33 g,显著高于城区的7.03 g(Z=- 2.750,P＜0.01)；除农村8～ 10岁儿童尿碘(228.6 μg/L)较高外,城区和农村成人(111.3、195.6μg/L)、孕妇(193.0、172.9μg/L)、哺乳期妇女(128.4、173.7 μg/L)和城区儿童(186.8μg/L)尿碘中位数显示,碘营养水平均处于适宜状态.农村成人和儿童的尿碘中位数(195.6、228.6μg/L)明显高于城区成人和儿童(111.3、186.8 μg/L,Z值分别为- 2.294、- 5.434,P＜ 0.05或＜0.01).城区和农村成人、哺乳期妇女和孕妇碘缺乏人群的构成[46.7％(28/60)、21.6％(13/60)；21.1％(19/90)、21.3％(18/89)；27.8％(25/90)、42.2％(38/90)]明显高于碘过量人群的构成[4.6％(4/60)、5.0％(3/60)；16.7％(15/90)、16.9％( 15/89)；4.4％ (4/90)、0.0％(0/90)],但农村儿童碘过量人群所占比例[26.3％(79/300)]明显高于碘缺乏人群[5.6％(17/300)].结论 哈尔滨市居民自然环境仍处于缺碘状态;除农村儿童外,居民的摄碘量和人群碘营养水平基本处于适宜状态,成人、哺乳期妇女和孕妇人群碘缺乏造成疾病的风险要高于碘过量造成的风险,农村儿童碘过量所致疾病风险要高于碘缺乏.因此,需加强对不同人群的监测,在落实科学补碘的同时根据不同人群加强科学补碘的宣传.     

Do peripartum and postmenopausal women with primary liver cancer have a worse prognosis? A nationwide cohort in Taiwan

BACKGROUNDWhile primary liver cancer (PLC) is one of the most common cancers around the world, few large-scale population-based studies have been reported that evaluated the clinical survival outcomes among peripartum and postmenopausal women with PLC.AIMTo investigate whether peripartum and postmenopausal women with PLC have lower overall survival rates compared with women who were not peripartum and postmenopausal.METHODSThe Taiwan National Health Insurance claims data from 2000 to 2012 was used for this propensity-score-matched study. A cohort of 40 peripartum women with PLC and a reference cohort of 160 women without peripartum were enrolled. In the women with PLC with/without menopause study, a study cohort of 10752 menopausal females with PLC and a comparison cohort of 2688 women without menopause were enrolled.RESULTSPatients with peripartum PLC had a non-significant risk of death compared with the non-peripartum cohort [adjusted hazard ratios (aHR) = 1.40, 95% confidence intervals (CI): 0.89-2.20, P = 0.149]. The survival rate at different follow-up durations between peripartum PLC patients and those in the non-peripartum cohort showed a non-significant difference. Patients who were diagnosed with PLC younger than 50 years old (without menopause) had a significant lower risk of death compared with patients diagnosed with PLC at or older than 50 years (postmenopausal) (aHR = 0.64, 95%CI: 0.61-0.68, P < 0.001). The survival rate of women < 50 years with PLC was significantly higher than older women with PLC when followed for 0.5 (72.44% vs 64.16%), 1 (60.57% vs 51.66%), 3 (42.92% vs 31.28%), and 5 year(s) (37.02% vs 21.83%), respectively (P < 0.001).CONCLUSIONPeripartum females with PLC have no difference in survival rates compared with those patients without peripartum. Menopausal females with PLC have worse survival rates compared with those patients without menopause.     

Cross-sectional correlates of fasting hyperinsulinaemia in post-menopausal women of different ethnic origin.

AIMS: In a large ethnically diverse nationwide sample of post-menopausal women we explored the relationship between fasting insulin levels, ethnicity, and a wide range of anthropometric, socio-economic, and lifestyle factors. METHODS: Subjects were post-menopausal women aged 50-79 years without diagnosed diabetes mellitus comprising a subsample (n = 3500) of the Women's Health Initiative (WHI) Clinical Trial and Observational Study. In a cross-sectional survey at baseline, we analysed the association between ethnicity and fasting insulin using analysis of covariance procedures and identified independent correlates of hyperinsulinaemia, defined by the 75th percentile cut point for each ethnic group. RESULTS: Fasting insulin levels were higher among African-American and Hispanic women than among non-Hispanic White or Asian women. These differences persisted after adjustment for age, educational attainment, total and central body obesity, adult weight change, family history of diabetes, smoking status, alcohol consumption, use of menopausal hormone therapy and physical activity. Higher levels of body mass index, waist-hip ratio, adult weight gain, and lower levels of total and moderate or strenuous recreational activity were independent correlates of fasting hyperinsulinaemia. Habitual walking was also inversely associated with fasting insulin. CONCLUSIONS: In this cross-sectional analysis, fasting insulin levels were higher among African-American and Hispanic post-menopausal women as compared with non-Hispanic White and Asian women. In addition, obesity, adult weight gain, and low levels of moderate or strenuous physical activity were independently associated with hyperinsulinaemia.     

Management of breast fibroadenomas

OBJECTIVE: To identify from the literature and clinical experience a rational approach to management of fibroadenomas of the breast. METHOD: Recent literature on detection, diagnosis, and natural history of fibroadenomas was reviewed. Experience with over 4,000 women evaluated in the breast clinic at the Tel-Aviv Medical Center contributed to the management strategies suggested by review of the literature. RESULTS: Fibroadenomas of the breast are common, accounting for 50% of all breast biopsies performed. Physical examination, sonography, and fine needle aspiration are effective in distinguishing fibroadenomas from breast cancer. Transformation from fibroadenoma to cancer is rare; regression or resolution is frequent, supporting conservative approaches to follow-up and management. CONCLUSION: Age-based algorithms that allow for conservative management and that limit excision to patients whose fibroadenomas fail to regress are presented.     

高碘地区妊娠晚期妇女与育龄妇女甲状腺功能的比较

探讨妊娠和高碘对妇女甲状腺功能及甲状腺自身免疫功能的影响.选择高碘地区(27.69±4.73)岁孕妇210例和(30.62±6.01)岁育龄妇女290例;采集空腹晨尿及静脉血,砷-铈催化分光光度法测定尿碘浓度,化学发光法测定血清游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)及灵敏促甲状腺激素(sTSH),放射免疫法测定血清甲状腺过氧化物酶抗体(TPOAb)和甲状腺球蛋白抗体(TGAb).孕妇和育龄妇女尿碘中位数分别为1 240.70μg/L和949.21μg/L,有94.3%的孕妇和81.0%的育龄妇女碘过量.孕妇和育龄妇女甲状腺疾病总患病率为22.9%和30.3%,孕妇甲状腺功能亢进症(甲亢)、亚临床甲亢、甲状腺功能减退症(甲减)、亚临床甲减的患病率分别为0.5%、1.9%、0.5%和20.0%.育龄妇女的甲亢、亚临床甲亢、甲减及亚临床甲减的患病率分别为2.8%、0.3%、0.3%和26.9%.孕妇的FT3、FT4水平低于育龄妇女[(4.03±0.59对4.71±1.04)pmol/L,(13.35±1.59对14.27±3.63)pmol/L,均P＜0.01],TGAb阳性率低于育龄妇女(7.1%对14.1%,P=0.014).高碘地区妇女甲状腺疾病患病率及甲状腺自身抗体阳性率较高,妊娠使孕妇甲状腺激素水平及TGAb阳性率较育龄妇女降低,建议育龄妇女及孕妇控制碘摄入,并加强甲状腺功能和甲状腺自身抗体的监测.

Abstract：

To explore the influences of pregnancy and iodine intake on thyroid function and immune functions, 210 pregnant women and 290 fertile women were chosen from iodine excess area, and the average ages of them were (27. 69±4. 73 )and (30. 62±6. 01 )years respectively. Fasting blood and urine were collected in the morning. The urinary iodine level was determined by arsenic-cerium catalytic contact. Serum free triiodothyronine ( FT3 ), free thyroxine ( FT4 ), and sensitive thyroid-stimulating hormone ( sTSH ) levels were measured by chemiluminescence.Thyroid peroxidase antibody (TPOAb)and thyroglobulin antibody (TGAb)were measured by radioimmunoassay. The median urinary iodine in the pregnant and fertile women were I 240. 70 and 949. 21 μg/L, respectively. There were 84. 3% pregnant women and 81.0% fertile women admitting excess iodine intake. The prevalence of overall thyroid diseases was 22. 9% in the pregnant women and 30. 3% in the fertile women. The prevalence of hyperthyroidism,subclinical hyperthyroidism, hypothyroidism, and subclinical hypothyroidism was0. 5%, 1.9%, 0. 5%, and 20. 0% in the former group, and 2. 8%, 0. 3%, 0. 3%, and 26. 9% in the latter. Both FT3 and FT4 levels of the pregnant women were lower than those of fertile women [(4. 03±0. 59 vs 4. 71 ± 1.04)pmol/L, ( 13. 35 ± 1.59 vs 14. 27 ±3.63 )pmol/L,both P＜0. 01], and the positive rate of TGAb of pregnant women was also lower than that of fertile women (7. 1% vs14. 1%, P=0. 014). The prevalence of thyroid diseases and positive rate of thyroid autoantibodies is high in women with excess iodine intake. Compared with fertile women, pregnancy may lead to decreas~s in level of thyroid hormones and positive rate of TGAb. Their iodine intake should be controlled, and the thyroid function and autoimmunity antibodies should be monitored.     

化学发光法检测孕前和孕期妇女TORCH结果分析

采用抗体捕获化学发光法对2010年5月～2011年12月来某院进行产前检查的孕妇与孕前查体妇女TORCH-IgM检测。孕前期妇女TORCH抗体阳性率为0.8%(45/5075),孕期妇女TORCH抗体阳性率为0.6%(11/1868)。其中HSV-Ⅱ-IgM抗体阳性率最高,孕前妇女为2.6%,孕期妇女为2.5%,明显高于其他病原体阳性率。提倡对孕前和孕期妇女进行TORCH-IgM筛查,对优生优育,提高出生人口素质有重要意义。