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重建钢板治疗C型骨盆骨折 总被引:1,自引:0,他引:1
C型骨盆骨折具有垂直和旋转不稳定性,重建后环需良好复位稳固内固定,对前环是否需要切开复位内固定尚存有争议。随内固定材料的改进,骨盆生物力学、解剖学及影像学研究的深化,骨盆前、后环骨折脱位临床内固定方式选择增多,不稳定的骨盆环治疗中骨盆前、后环手术重建非常重要。本院从2004年9月至2007年9月25例C型骨盆骨折行前、后环重建钢板内固定,效果满意,报告如下。 相似文献
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内固定在脊柱结核治疗中的作用(附22例初步报告) 总被引:8,自引:4,他引:8
目的:探讨内固定在脊柱结核治疗中的作用。方法:1991年5月-2001年2月共开展脊柱结核内固定手术22例(其中1例先做头颅骨盆环牵引,后做内固定手术),使用的固定器械;鲁氏棒 椎板下钢丝6例,Dick椎弓螺钉系统8例,Harrington rod5例,SDRS2例,USS1例,结果:本组22例脊柱结核内固定手术均未引起炎症扩散,在脊柱结核一期病灶清除,同时或二期内固定12例中卧床时间比无内固定手术缩短4-8周,结论:在脊柱结核治疗中内固定手术可以加强脊柱稳定,缩短卧床时间,预防或矫正畸形。但是,脊柱结核必定是一种特异性感染,选择适应证时还要慎重,有些细节问题还要进一步探讨。 相似文献
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动力髋螺钉治疗股骨粗隆间骨折失效分析 总被引:2,自引:0,他引:2
目的通过回顾性分析2000年1月至2007年4月动力髋螺钉内固定治疗156例股骨粗隆间骨折病例,探讨31例动力髋螺钉内固定治疗股骨粗隆间骨折失效的原因。方法利用股骨粗隆间骨折Evans分型,从尖顶距值和骨质疏松等方面对内固定失效结果进行统计分析。结果Evans分型Ⅰ型无失效病例,Ⅴ型失效比例最大,为44.4%;尖顶距值在25mm以下时,无内固定失效病例,若尖顶距值大于45mm时,内固定失效比例达80.6%;在不稳定型骨折中,骨质疏松组内固定失效比例最大,为39.3%。结论动力髋螺钉内固定要选择合适的适应证;深刻理解熟练掌握动力髋螺钉应用技术;动力髋螺钉内固定失效同骨质疏松严重程度有关。 相似文献
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Cervifix内固定术治疗下颈椎骨折脱位 总被引:2,自引:0,他引:2
颈椎侧块内固定术在下颈椎骨折脱位后路内固定中日趋得到重视。白2000年7月~2002年6月采用AO-Cervifix内固定加植骨融合术,治疗下颈椎骨折脱位16例,疗效满意。 相似文献
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切开复位内固定治疗胫骨Pilon骨折 总被引:13,自引:1,他引:12
目的:评价切开复位内固定术对Pilon骨折的治疗效果。方法:自1993年3月-1998年10月,应用切开复位内固定治疗Pilon骨折35例,其中18例行胫骨关节面的有限固定,17例行前或内铡支撑钢板固定,随访0.5-5年,按Helfet标准进行功能评价。结果:23例Ⅱ型损伤中,优良率为85%;Ⅲ型损伤的12例中,优良率为50%。结论:治疗的效果决定于原始损伤的程度、复位的质量和固定的稳定性。切开复位内固定是一种疗效满意的治疗方法之一。 相似文献
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内固定治疗髌骨骨折失效32例原因分析 总被引:11,自引:0,他引:11
自1987年6月~2002年8,月,我院共收治髌骨骨折458例,得到随访324例患者中32例出现内固定失效,占9.9%。为了进一步提高内固定的疗效,现结合本组资料及有关文献对内固定失效原因及预防措施加以探讨并报告如下。 相似文献
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四肢长骨骨折内固定失败原因分析 总被引:3,自引:0,他引:3
四肢长骨骨折内固定失败原因分析海光剑章核验我院1987年5月~1994年12月收治因内固定失败再次住院者43例,本文就失败原因和预防讨论如下:1临床资料(1)内固定物种类:43例中52处骨折行内固定手术。普通钢板27例(处),加压钢板3例,V型髓内针... 相似文献
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半月板组织工程的研究进展 总被引:1,自引:1,他引:0
半月板损伤临床常见,据美国矫形外科学会2008年的统计资料,美国每年全膝关节置换手术>250000例,其中半月板损伤是骨性关节炎进展的关键因素。然而,半月板仅外周1/3有血液供应,发生于此部位的损伤采用缝合治疗可以愈合;而内侧缘2/3均为无血管区,损伤后自行愈合能力较差,目前临床上针对这类损伤多采用半月板部分切除或全部切除术。 相似文献
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Improved sexual behavior in male rats treated with a Chinese herbal extract: hormonal and neuronal implications 总被引:3,自引:0,他引:3
Zanoli P Benelli A Zavatti M Rivasi M Baraldi C Baraldi M 《Asian journal of andrology》2008,10(6):937-945
Aim: To investigate the influence of an extract obtained from five Chinese medicinal plants on sexual behavior of adult male rats. Methods: The extract was administered at doses of 30, 60 and 120 mg/kg by oral gavage, acutely (one time, 45 min before mating test) or subchronically (daily for 10 days) in sexually potent and sexually sluggish/impotent rats. Sexual behavior, serum levels of luteinizing hormone (LH) and testosterone (T) were evaluated in treated rats and compared with controls receiving vehicle. The effect of the extract on central dopaminergic neurotransmission was assessed in the nucleus accumbens using a microdialysis technique. Results: In sexually potent rats, both acute and subchronic treatment with the extract dosed at 30 and 60 mg/kg reduced mount latency and intromission latency. In sluggish/impotent rats, the acutely administered extract at the dose of 60 mg/kg shortened ejaculation latency, whereas subchronically administered at the doses of 30 and 60 mg/kg, reduced mount, intromission and ejaculation latencies, increasing also the percentage of mounting and ejaculating rats. The extract dosed at 60 mg/kg significantly increased LH and T following acute and subchronic administration and increased 3,4-dihydroxyphenylacetic acid levels in the nucleus accumbens, 30 min after the acute administration. Conclusion: The improvement in both appetitive and consummatory components of sexual behavior observed in male rats treated with the extract could be ascribed to increased serum T level in parallel with the activation of the central dopaminergic system. 相似文献
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Gonadotrophin-releasing hormone-Ⅰ and -Ⅱ stimulate steroidogenesis in prepubertal murine Leydig cells in vitro 总被引:1,自引:0,他引:1
Aim: To study the effect and mechanism of gonadotrophin-releasing hormone (GnRH) on murine Leydig cell steroidogenesis. Methods: Purified murine Leydig cells were treated with GnRH-Ⅰ and -Ⅱ agonists, and testosterone production and steroidogenic enzyme expressions were determined. Results: GnRH-Ⅰ and -Ⅱ agonists significantly stimulated murine Leydig cell steroidogenesis 60%-80% in a dose- and time-dependent manner (P 〈 0.05). The mRNA expressions of steroidogenic acute regulatory (STAR) protein, P450scc, 3β-hydroxysteroid dehydrogenase (HSD), but not 17β-hydroxylase or 17β-HSD, were significantly stimulated by both GnRH agonists with a 1.5- to 3-fold increase (P 〈 0.05). However, only 3β-HSD protein expression was induced by both GnRH agonists, with a 1.6- to 2-fold increase (P 〈 0.05). Conclusion: GnRH directly stimulated murine Leydig cell steroidogenesis by activating 3β-HSD enzyme expression. 相似文献
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Aim: To investigate the effects of 17β-estradiol (E2), Peganum harmala extract (PHE) and caloric restriction (CR) on various testis parameters during aging. Methods: Twelve-month-old male rats were treated for 6 months with either E2 or PHE, or submitted to CR (40%). Results: Our results show that estrogens and CR are able to protect the male gonad by preventing the decrease of testosterone and E2 levels as well as the decrease of aromatase and estrogen receptor gene expressions. Indeed, E2, PHE and CR treatments induced an increase in the superoxide dismutase activities and decreased the activity of testicular enzymes: gamma-glutamyl transferase, alkaline phosphatase, lactate deshydrogenase as well as the aspartate and lactate transaminases in aged animals. In addition, the testicular catalase and gluthatione peroxidase activities were enhanced in E2, PHE and CR-treated rats compared to untreated animals at 18 months of age. Moreover, the positive effects of estradiol, PHE and CR were further supported by a lower level of lipid peroxidation. Recovery of spermatogenesis was recorded in treated rats. Conclusion: Besides a low caloric diet which is beneficial for spermatogenesis, a protective antioxydant role of estrogens is suggested. Estrogens delay testicular cell damage, which leads to functional senescence and, therefore, estrogens are helpful in protecting the reproductive functions from the adverse effects exerted by reactive oxygen species (ROS) produced in large quanti- ties in the aged testis. 相似文献
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微创经皮钢板内固定治疗胫骨骨折 总被引:5,自引:4,他引:1
2005年3月~2008年3月,我科采用微创经皮钢板内固定治疗胫骨骨折34例,疗效满意。1材料与方法1.1病例资料本组34例,男20例,女14例,年龄12~68岁。致伤原因:交通事故24例,坠落伤4例,砸伤6例,均为闭合性损伤。合并多发骨折8例,颅脑、胸腹损伤6例。其中胫骨近端损伤7例,胫骨干损伤17例,胫骨远端损伤10例,合并腓骨骨折28例,合并下胫腓联合分离3例。 相似文献