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1.

Ethnopharmacological relevance

Traditional medicine plays an important role in the daily lives of the people of Uganda to treat a wide range of health problems. Our study presents results of an ethnobotanical inventory conducted to identify and document medicinal and nutritional plants used in the management of opportunistic infections associated with human immunodeficiency virus / acquired immunodeficiency syndrome (HIV/AIDS), the plant parts used, preparation and administration methods of herbal remedies.

Materials and methods

We performed semi-structured interviews with 79 respondents (women 78%, men 22%), who included specialists in medicinal plants (such as traditional birth attendants and herbalists) and non specialists with general knowledge of plant use. Respondents answered a semi-structured questionnaire regarding their knowledge of plants and general treatment practices including management of HIV/AIDS opportunistic infections. The reported plants were collected and identified. Data were analyzed using factor informant consensus and fidelity level to determine homogeneity of informants? knowledge on medicinal and nutritional plants suitable for different ailment categories and the most preferred plant species used to treat each ailment category in the study areas.

Results

The study revealed 148 plant species belonging to 54 families, most of which were herbs (50.7%). Leaves (61.6%) were the most frequently used parts in remedy preparations which were mainly administered orally (72%). The majority of plants (62%) were harvested from wild habitats. The most important species according to fidelity values are Hibiscus sabdariffa L. for anaemia, Mangifera indica L. for cough, Zehneria scabra (L. F.) Sond. for skin infections, Rhus natalensis Bernh.ex.Krauss for diarrhoea and Tarenna pavettoides (Harv.) Sim for appetite boosting. The factor informant consensus highlighted the agreement in the use of plants and showed that the respiratory infections category had the greatest agreement (0.60). Family Asteraceae accounted for 15% of the total species recorded. Sixty plant species (40%) of the plants provide nutritional support.

Conclusion

The study revealed that folk medicine is still widely practised. Fidelity level values indicate that these plants are the most preferred species for particular ailments. The high consensus value (0.6) indicated that there was high agreement in the use of plants for respiratory ailments among others. These preferred plant species could be prioritized for conservation and subjected to chemical screening to ascertain their pharmacological activities.  相似文献   

2.
Traditional medicine usage in rural Ugandan population for day-to-day health care needs is close to 90%. Women and children form the bulk of the people reliant on herbal medicine. This study was undertaken to document how ethnomedical folklore aids childbirth in rural western Uganda by conducting field surveys, discussions and interviews with the resource users (mothers) and health providers (traditional birth attendants). Health surveys revealed that over 80% of childbirths are conducted at home by using herbal remedies in Bushenyi district. Seventy-five plants have been recorded for usage in inducing labour and some of these plants may be oxytocic. The dilemma lies in the toxicity levels and the unspecified dosages that may threaten the life of the unborn baby and the mother. The high population growth rate, high total fertility rate coupled with high maternal mortality and morbidity in Uganda calls for rethinking in gendered health provision policies and programmes for which herbal medicine integration in health care systems seems viable.  相似文献   

3.

Aim of the study

The objective of the study was to investigate and document the utilization of medicinal (with emphasis on anthelmintic) plants by the people of Loitoktok district in Kenya for the management of both animal and human health.

Materials and methods

The study was conducted between May and October 2009. Information was gathered from 23 traditional health practitioners, from across the district, by use of semi-structured questionnaires; transect walks, oral interviews and focus group discussions. Voucher specimens of cited plants were collected and deposited at the botanical herbarium of the University of Nairobi.

Results

A total of 80 medicinal plants cited were collected and identified as belonging to 46 families and 70 genera. The plants identified were 48%, 38%, 7%, 6% and 1% trees, shrubs, herbs, lianas and lichens, respectively. Most of the plants belonged to the families Fabaceae (10%), Euphorbiaceae (6%), Rutaceae (5%) followed by Boraginaceae, Labiateae, Rubiaceae, and Solanaceae at 4% each. However, the six most important families by their medicinal use values in decreasing order were Rhamnaceae, Myrsinaceae, Oleaceae, Liliaceae, Usenaceae and Rutaceae. The ailments treated included respiratory conditions, helminthosis, stomach disorders, malaria, sexually transmitted diseases, infertilities and physical injuries. Helminthosis in both livestock and humans was recognized as a major disease managed by use of medicinal plants (with an informant consensus factor of 0.86) in the study area. The most frequently used plant anthelmintics were Albizia anthelmintica (Fabaceae), Myrsine africana (Myrsinaceae), Rapanea melanophleos (Myrsinaceae), Clausena anisata (Rutaceae) and Olea Africana (Oleaceae) used by 70%, 70%, 26%, 13% and 9% of the respondents, respectively. Other plant anthelmintics used, each by 4% of the respondents, were Rumex usambarensis (Polygonaceae) and Salvadora persica (Salvadoraceae).

Conclusion

It is concluded that traditional health practice in Loitoktok depend largely on naturally growing plants and that the study area has a potential for bio-prospecting of crude drugs from plants due to the large number of medicinal plants cited. There is also need for further studies to validate the plants used in medicinal remedies in this area.  相似文献   

4.

Ethnopharmacological relevance

Skin diseases have been of major concern recently due to the association of skin opportunistic infections and HIV/AIDS, are usually the first sign of HIV infection and conversion to AIDS. More than 90% of HIV-infected individuals develop skin and mucosal complications at some stage during the disease. Although classical medicine is undoubtedly addressing these diseases, the people of the Eastern Cape, South Africa still depend, to a large extent on traditional herbal medicine for the treatment of various diseases. The current study was undertaken to investigate the local peoples characterisation of skin diseases/disorders and to document the medicinal plants used for various skin disorders among the Xhosa-speaking communities of the Amathole District, Eastern Cape.

Materials and methods

Information was obtained by interviewing 54 respondents in 7 locations. Collection of the reported medicinal plants from the wild was assisted by the informants and identification of the collected plants specimens was done with the help of floristic works of South Africa. Quantitative methods including the use-value and the informant consensus factor (ICF) were computed for determining the relative importance of species known locally and the homogeneity of the informants? knowledge respectively.

Results

Twenty five skin disorders, classified under 5 categories are being treated with the listed medicinal plants in the study area. The highest ICF (0.45) was linked to bacteria-related skin disorders. This category comprised of 57 use citations, 3 skin disorders; with sore throat being the most frequently mentioned (4.2%). In this study, 106 plant species distributed in 61 families and 107 genera were identified as being used to treat one or more of the skin disorders. The species with the highest use-value was Aloe ferox Mill. (Xanthorrhoeaceae) known locally as Umhlaba. The most representative families were Solanaceae and Asteraceae with 6 species each, followed by Fabaceae, Poaceae and Rutaceae (5 species each). The leaves were the most frequently used plant part, followed by the bark (10%) and fruits (7%). Administration of the different plant parts was mostly topical (77%) on the affected area.

Conclusion

A total of twenty five skin disorders/conditions, classified under 5 categories are being treated with the listed medicinal plants in the study area. 106 plant species distributed in 61 families and 107 genera were identified as being used to treat one or more of the skin disorders. The species with the highest use-value was Aloe ferox Mill. (Xanthorrhoeaceae) known locally as Umhlaba. The most representative families were Solanaceae, Asteraceae, Fabaceae, Poaceae, Rutaceae and Euphorbiaceae. Majority of the plant species were herbs and the leaves were the most frequently used, mostly applied topically as a paste, powder or sap on the affected skin area.  相似文献   

5.

Ethnopharmacological relevance

The study was done to establish medicinal plants used in the treatment of various diseases by the people in the Northern sector of Kibale National Park in western Uganda. It was also aimed at establishing the plant parts used and the mode of preparation of remedies. These plants create a basis for phytochemical evaluation which can lead to the discovery of biologically active compounds that can be used as starting materials in the development of new drugs targeting selected diseases such as malaria.

Materials and methods

The required information was obtained using open interviews, semi-structured questionnaires, focus group discussions and transect walks.

Results

Different medicinal plants (131 species) distributed over 55 families were observed to be used by the local communities around the Northern sector of Kibale National Park. The plants as reported in this paper are used to treat 43 physical illnesses/diseases. The most used parts of the plants are the leaves. Water is the main medium used for the preparation of the remedies which are mostly administered orally.

Conclusion

The people in the study area have a rich heritage of traditional plants that are used in the health care system to treat diseases. These medicinal plants have contributed significantly to several disease therapies. The most common diseases treated are malaria and cough, which are mostly treated by Vernonia amygdalina Del. and Albizia coriaria Welw. respectively. The main sources of medicinal plants include bush land, home gardens, grasslands, and the forest.  相似文献   

6.

Ethnopharmacological relevance

The purpose of this study was to carry out a survey and document plants used in Meru-central district by traditional healers with emphasis on those used as biopesticides.

Materials and methods

The study was carried out at Igane and Gatuune sub-locations, Abothuguchi East division of Meru-Central district, Kenya. The data collection involving 23 traditional healers was done using semi-structured questionnaire, focused group discussion and transect walks. Plants samples were collected and botanically identified at the herbarium of the Department of Land Resource Management and Agriculture Technology in the University of Nairobi.

Results

The results of the ethnobotanical survey revealed that herbalists belonged to both gender with the majority being male (82.6%) and female (17.4%). Their ages ranged from 28 to 82 years. Seventy (70) plant species, belonging to 35 families, were identified as being used as biopesticides and also as medicinal. The families encountered were Asteraceae (10%), Euphorbiaceae (8.6%), Lamiaceae (8.6%), Fabaceae(8.6%), Caesalpiniaceae (5.7%), Rubiaceae (5.7%), Liliaceae (4.3%), Apocynaceae (2.9%), Flacourtiaceae (2.9%), Verbenaceae (2.9%) and the rest of the 24 families had 1.4% each. These medicinal plants were used to treat and manage a wide range of diseases and conditions including parasitic, microbial, helminthosis, protozoa, cuts and wounds, fractures, dental, arthritis, allergic, snake bites, reproductive as well as metabolic. Among the plants used, shrubs were the commonest at 42.8%; trees were 32.9%, while herbs and liana were at 22.9% and 1.4%, respectively. Majority of the respondents used leaves, roots and bark to make their herbal preparations with only a few using seeds, flowers, whole plant, flower sap and pods. The plants that were cited by the respondents to be used as biopesticides were Prectranthus barbatus Andr. (47.8%), Tephrosia vogelii Hookf. (39.1%), Ocimum gratissimum L (34.7%), Vernonia lasiopus O.Hoffm. (8.7%), Cascabella thevetia( L.)Lippold (4.3%) and Oncoba routledgei Sprague (4.3%).

Conclusion

Meru central district is rich in biodiversity of biopesticides and other medicinal plants and there is need for further pharmacological studies to validate their use as potential drugs for pests and disease control.  相似文献   

7.

Ethnopharmacological relevance

There is very limited information regarding plants used by traditional healers for treating diabetes in Bangladesh, let alone compilation on the use of those. This study aimed at collecting and documenting information on antidiabetic plants traditionally used in the treatment of diabetes.

Materials and methods

The survey was carried out in a period of almost 2 years. Fieldwork was undertaken in total of 15 districts of Bangladesh. Open-ended and semi structured questionnaire were used to interview a total of 1060 people including traditional healers, Ayurvedic/Unani drug manufacturers and local people.

Results

A total of 83 plant species of 38 families were listed. Leaves were the most cited plant part used against diabetes. Most of the reported species were tree in nature and decoction is the mode of preparation of major portions of the plant species. Most of the plant species were very common and were cultivated or planted in homestead or roadsides.

Conclusion

Conventional use of many antidiabetic plants of Bangladesh can be rationalized by the presence of active compounds found in those plants. The documentation could be important for the conservation of these plants and represent the preliminary information required for future phytochemical investigation.  相似文献   

8.

Ethnopharmacological relevance

This study documented the pharmaceutical importance of plant resources in Nhema communal area, particularly the significance of medicinal plants in primary healthcare. This is reflected in the great diversity of plants used for medical purposes as well as in their wide range of medicinal applications. Such rich ethnobotanical knowledge and repository of medicinal plants reinforces the need for an evaluation of their biological activity as a basis for developing future medicines.

Materials and methods

In order to document information on medicinal plants used for primary health care and to maximize the collection of indigenous knowledge in Nhema communal area, nine traditional healers were identified using the Participatory Rapid Appraisal (PRA) approach. Data was collected through open-ended interviews with traditional healers, between January and May 2008.

Results

A total of 61 plant species representing 45 genera and 28 families were found to be commonly used in the treatment of 34 different human health problems. More than a third of the plant species were used for diarrhoea, which is a prevalent disease in the study area. The root was the most commonly used plant part while decoction was the most common method of traditional drug preparation.

Conclusions

Nhema communal area in the Midlands province, Zimbabwe is endowed with a strong culture of herbal medicine usage for primary healthcare. This is reflected in the number of medicinal plants used and the human ailments they treat. This preservation of indigenous knowledge is due to continued reliance on wild plant resources for primary healthcare by the local community. Deforestation and unsustainable rates of plant use are a serious threat on continued utilization of plant resources for primary healthcare.  相似文献   

9.

Ethnopharmacological relevance

Diabetes mellitus is a growing problem in many developing countries and the financial burden associated with it is enormous. In traditional African communities, majority of people relies on traditional medicines and Traditional Health Practitioners as the primary source of health care. Hence, this study was undertaken in the Lower Eastern province of Kenya to document the medicinal plants used by the traditional practitioners to treat diabetes and to assess the existing knowledge in management of this condition.

Materials and methods

Data was collected using structured open- and close-ended questionnaires.

Results

Thirty-nine species belonging to 33 genera and 26 families were encountered and the most frequently cited species were from Caesalpiniaceae, Ebenaceae, Solanaceae and Labiatae families. Twenty-eight percent of the plant species are reported to have hypoglycaemic activity.

Conclusions

Currently there is no data on medicinal plants used to treat diabetes in Kenya. Therefore, these findings are important in the management of diabetes and future research on traditional medicine in drug development.  相似文献   

10.

Introduction and objectives

In Uganda, there are over one million people with HIV/AIDS. When advanced, this disease is characterized by life-threatening opportunistic infections. As the formal health sector struggles to confront this epidemic, new medicines from traditional sources are needed to complement control efforts. This study was conducted to document herbal medicines used in the treatment of HIV/AIDS and related opportunistic infections, and to document the existing knowledge, attitudes and practices related to HIV/AIDS recognition, control and treatment in Sembabule, Kamuli, Kabale and Gulu districts in Uganda.

Methods

In this study, 25 traditional medicine practitioners (TMPs) were interviewed using structured questionnaires.

Results

The TMPs could recognize important signs and symptoms of HIV/AIDS and its associated opportunistic infections. The majority of practitioners treated patients who were already receiving allopathic medicines including antiretroviral drugs (ARVs) prescribed by allopathic practitioners.There were 103 species of medicinal plants identified in this survey. Priority plants identified include Aloe spp., Erythrina abyssinica, Sarcocephalus latifolius, Psorospermum febrifugum, Mangifera indica and Warburgia salutaris. There was low consensus among TMPs on the plants used. Decoctions of multiple plant species were commonly used except in Gulu where mono-preparations were common. Plant parts frequently used were leaves (33%), stem bark (23%) and root bark (18%). About 80% of preparations were administered orally in variable doses over varied time periods. The TMP had insufficient knowledge about packaging and preservation techniques.

Conclusions

Numerous medicinal plants for treatment of HIV/AIDS patients were identified in the four districts surveyed and the role of these plants in the management of opportunistic infections warrants further investigation as these plants may have a role in Uganda's public health approach to HIV/AIDS control.  相似文献   

11.
目的 探索高效联合抗逆转录病毒疗法(HAART)结合中医分期辨证治疗HIV/AIDS患者的治疗方案,以达到重建HIV感染者、患者的免疫功能,抑制HIV病毒复制,减少并发症及HARRT药物不良反应的目的.方法 29例HIV/AIDS患者依据国家标准分组,将3例无症状HIV感染者列入...  相似文献   

12.

Aim of the study

We studied traditional knowledge (TK) and current uses of medicinal plants among the inhabitants of the Arribes del Duero-ARD-(Spain), documenting traditional medical practices.

Materials and methods

We interviewed 80 key informants (44 men and 36 women). Their average age was 72 years (range 48-98 years). We calculated the cultural importance for each species cited. To analyze how TK varies with the characteristics of the different informants, we performed an ANCOVA, taking the number of use-reports (URs) provided by each informant as a variable to model, and age and gender as explanatory variables.

Results and conclusions

156 medicinal remedies were recorded; they were based on a single species and were cited by at least three independent informants, and half of them are still in use today. These remedies are related to nine major organ systems and 54 therapeutic uses, and 70 species (belonging to 39 families) are used, most of which are herbs (64%). The most relevant family is the Lamiaceae (23 remedies, 8 species) and the species employed in the greatest number of remedies (8) is Urtica dioica L. However, the taxon with the greatest cultural value is Hypericum perforatum L. (CI = 0.71). 31% of the variability of the TK can be explained in terms of the age and gender of the informants (R2 = 0.315), the age factor having a positive effect. Most of the remedies are related to the treatment of unimportant ailments, referring to disorders of the skin, and the respiratory and digestive systems. The leaves and fruits are the most frequently sought plant parts (40 and 17% of the plants mentioned, respectively), and infusions (34%) and decoctions (28%) are the main methods used for preparing the remedies. Likewise, we recorded remedies based on plant mixtures and ethnomedicinal novelties or rare uses, and comment on the influence exerted by superstition.Currently, many people preserve a rich TK about medicinal plants, and it may be affirmed that the folk medicine is still very much alive in the ARD, above all as regards the treatment of certain common afflictions or unimportant ailments.  相似文献   

13.
艾滋病四诊信息采集表的研制与应用   总被引:1,自引:0,他引:1  
目的:在中医理论指导下研制艾滋病四诊信息采集表,以HIV/AIDS的共性表现和脏腑相关的特异性症状为基础,体现中医症状信息,观察HIV/AIDS人群的健康状况和治疗过程的病情变化,探索艾滋病中医证候类型以及分布特征。方法:遵照国际通用量表研制的程序化方法,在中华文化背景下和中医理论指导下,结合艾滋病相关概念内涵,构建了艾滋病四诊信息采集表的结构及条目池,又组织多次专家论证,探讨该表的结构及项目组成,通过现场调查,进行项目分析,完善调查表并确定其信、效度。结果:通过对133例临床调查资料的因子分析、相关系数和内部一致性分析等统计分析筛选条目,根据不同分析结果选中的条目综合考虑,形成了由6个方面、57个条目组成的艾滋病四诊信息采集表。初步考核结果表明,该量表具有良好的结构效度,6个方面的克朗巴赫信度系数分别为0.851、0.896、0.880、0.950、0.868、0.863。结论:艾滋病四诊信息采集表是按照国际通用的方法研制而成的,为艾滋病中医证候学研究提供了1个有效的工具。  相似文献   

14.
目的:通过文献研究,了解艾滋病中医证候研究的现状。方法:采用频数统计方法,对中医药治疗艾滋病的证候研究以及临床研究文献资料从证候分布和证候组成的症状特点两个方面进行分析。结果:从病例频次统计,证候依次是气阴两虚、湿热内蕴、肝郁气滞、气虚血瘀、气血两虚、热盛痰蒙等。症状频次依次是乏力、皮疹、发热、咳嗽、腹泻、胸闷、纳呆、自汗、头痛、消瘦。结论:根据本研究结果分析,艾滋病中医常见证候分布以气阴两虚、湿热内蕴、肝郁气滞为主;症状以乏力、皮疹、发热、咳嗽、腹泻为主。  相似文献   

15.
16.

Ethnopharmacological relevance

Given the increasing coverage of antiretroviral therapy (ART) for HIV/AIDS treatment as well as the high utilization of herbal medicine, many persons living with HIV/AIDS in sub-Saharan Africa are thought to practice medical pluralism, or the adoption of more than one medical system for their care and treatment. Using a cross-sectional study we sought to document and identify the herbal medicines used by persons living with HIV/AIDS on Mfangano Island, Suba District, Nyanza Province, Kenya.

Materials and methods

We interviewed herbalists and knowledgeable mothers to obtain information regarding medicinal plants, particularly for HIV/AIDS-related symptoms, HIV/AIDS, and chira (an illness concept with similarities to HIV/AIDS regarding sexual transmission and wasting symptoms). Using systematic sampling, 67 persons living with HIV/AIDS (49 of whom were receiving ART) were selected from an Mfangano Island health clinic and participated in semi-structured interviews.

Results

Interviews with herbalists and mothers identified 40 plant species in 37 genera and 29 families that a person with HIV/AIDS or chira could use for herbal remedies. Overall, 70.1% of persons living with HIV/AIDS had used medicinal plants after HIV diagnosis, most commonly to treat symptoms related to HIV/AIDS. In addition to common vegetables and fruits that can serve medicinal purposes, Azadirachta indica A. Juss. (Meliaceae), Carissa edulis (Forssk.) Vahl (Apocynaceae), and Ximenia americana L. (Olacaceae) were the most frequently cited medicinal plants used by persons living with HIV/AIDS.

Conclusions

Collaboration and communication between biomedical clinicians and herbalists should be encouraged given high rates of concomitant ART-herb usage. Pharmacological, toxicological, and ART-herb interaction studies based on the plants identified in this study and their constituent ingredients should be considered.  相似文献   

17.
冀爱英  杨新勇  李艳丽 《新中医》2007,39(11):36-38
目的:观察益艾康胶囊治疗HIV/AIDS的临床疗效。方法:将95例HIV/AIDS患者按CD_4~ 细胞计数分为2组,中药组52例以益艾康胶囊治疗;联合组43例以益艾康胶囊加抗病毒药物治疗。观察临床症状、体征及CD_4~ 细胞的变化。结果:总有效率中药组为80.0%,联合组为80.4%,2组比较,差异无显著性意义(P>0.05)。2组治疗后CD_4~ 细胞多数逐渐上升或稳定,总有效率中药组为56.7%,联合组为56.9%,2组比较,差异无显著性意义(P>0.05)。结论:益艾康胶囊可显著改善HIV/AIDS患者临床症状、体征,提高CD_4~ 细胞水平,减轻抗病毒药副反应,提高患者依从性。  相似文献   

18.
目的:了解河南省HIV/AIDS患者的主要症状和证候类型。方法:采用临床流行病学方法,被调查者按照统一标准填写《艾滋病中医四诊信息采集表》,收集临床资料进行数据分析,了解其主要症状和证候特点。结果:通过对54个主观症状进行因子分析,共提取出18个公因子并结合碎石图,得到4个主公因子分别为气虚因子、湿热因子、气逆因子和气滞因子。结论:河南HIV/AIDS患者的中医证候以脾气虚弱证为主,兼有湿热蕴结证和气滞证,其病位以脾为主,涉及肾、肝、胃、心、肺等多个脏腑。  相似文献   

19.
艾滋病作为现代一种新出现的病种,其复杂多变的病情及演变仍未被中医传统理论全面系统的阐释.本文从阐述气是构成和维持人体生命活动的基本物质、气虚的病理表现、艾滋病中医证候学研究、气虚病机在艾滋病治疗中的应用多方面进行分析,认为气虚为HIV/AIDS的基础病机,在脏为脾,涉及五脏.  相似文献   

20.
目的:通过对河南省农村艾滋病高发区的艾滋病毒感染者和艾滋病患者(HIV/AIDS)进行艾滋病认知、态度、行为的调查,提出针对性强的宣传防控政策性建议。方法:采用临床流行病学、统计学等方法,自行设计调查问卷,对308例HIV/AIDS进行问卷调查。结果:HIV/AIDS共同就餐、握手和拥抱的知识知晓率均超过90%,共用毛巾和共用马桶、游泳池的知晓率均超过80%,但对共用注射器和蚊虫叮咬知晓率低;获得知识的途径依次为医生宣讲、板报图书、电视广播、同乡朋友亲戚告知、知识讲座和网络;45.1%担心别人知道自己得病,64.0%感觉对自己的生活有影响;配偶感染率48.7%;近6个月与配偶性生活使用安全套使用率为从未使用者5.8%、有时使用者34.5%、经常使用者25.7%、一直使用者33.9%。结论:艾滋病知晓率较高,知识获取途径以医生宣讲、板报图书和电视广播为主,安全套使用率低,应针对患者特点采取有针对性的干预措施。  相似文献   

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