Desmoplastic fibroma of the axis. A case report

Desmoplastic fibroma of the bone appears in a wide variety of bones but rarely involves the spine. A 24-year-old male with desmoplastic fibroma of the axis treated by complete resection and posterior spinal fusion is reported. There was no recurrence of the tumor three years after surgery. Complete resection and reconstructive surgery for spinal instability are recommended for this benign spinal tumor.     

Desmoplastic fibroma of the ulna. A case report

This report of desmoplastic fibroma of bone (DFB) in the left ulna represents the 56th published case of the neoplasm. To the best of the authors' knowledge, the present case is the first instance of this type of excision of the distal ulna performed for DFB with a metallic prosthesis and successful restoration of distal radial ulnar anatomy and function.     

Desmoplastic fibroma of the first metatarsal. A case report

Desmoplastic fibroma is a benign but frequently aggressive tumor of bone. A 27-year-old man was treated for this lesion in the first metatarsal. The lesion recurred, extending into the medial cuneiform necessitating ray resection. The similar clinical and histologic findings of this tumor and other tumors, both benign and malignant, makes familiarity with the character of desmoplastic fibroma essential for proper treatment.     

Desmoplastic fibroma of the hand: case report

Desmoplastic fibroma is a benign tumor of the soft tissue and rarely of the bone. It typically presents in the trunk and proximal limbs, but it is quite rare in the hands. We present a rare case of desmoplastic fibroma of the soft tissues of the hand that presented as a slow-growing, painless, well-encapsulated mass.     

Desmoplastic fibroma of bone. A report of six cases

The clinical and pathological features of six cases of desmoplastic fibroma of bone are presented. Desmoplastic fibroma is rarely seen as a primary tumour of bone; when it does occur the sites of predilection are the long bones, but other sites such as the scapula and os calcis can be involved. Radiographically the lesion tends to expand the bone from within; it is well-demarcated and lytic, often with a trabeculated soap-bubble appearance. The cellular structure and the morphological arrangement are similar to those of aggressive fibromatosis of soft tissues. Differential diagnosis from malignant spindle-cell lesions of bone is important because the treatment of choice for desmoplastic fibroma of bone is simply excision with a thin layer of healthy tissue.     

Desmoplastic fibroma of mandible in a child: case report

The aim of this report is to present a rare case of a child with a desmoplastic fibroma (DF) at the mandibular angle. This lesion commonly shows a radiolucent and radiopaque radiographic picture. Due to its aggressiveness and high recurrence rate, an early diagnosis is essential and the complete removal of the lesion is the treatment of choice. We present a case of 11-year-old boy who was referred to be treated for an growth in the left mandibular angle area, a radiolucent and radiopaque feature. After an incisional biopsy, the complete removal of the lesion was done without vascular or nerve damage of the inferior alveolar bundle and without causing mandibular discontinuity. The clinical and radiographic features suggested the diagnosis and allowed the differentiation of DF from other lesions in the maxillofacial area. However, the final diagnosis was only possible through histopathological examination.     

Desmoplastic fibroma of the jaw: a case report and review of literature.

Desmoplastic fibroma is a benign intraosseous neoplasm that is recognized as the intraosseous counterpart of soft tissue fibromatosis in both gnathic and extragnathic sites. It has a propensity for locally aggressive behavior and local recurrence. In the present report, we define the clinicopathological and radiographic features of a desmoplastic fibroma of the mandible in an 8-year-old white boy who initially presented with a 2-month history of a rapidly expanding, painless mass along the right inferior border of his mandible. A critical and comprehensive review of the English language literature is also provided.     

Desmoplastic fibroma of bone. Case report and literature review

A case is described of the rare, benign intraosseous desmoplastic fibroma, occurring in the humerus of a 20-year-old woman. A total of 121 cases is briefly reviewed and a table of 78 references dealing with desmoplastic fibroma is given. Treatment with indomethacin and ascorbic acid is proposed for cases of desmoplastic fibroma of bone when mutilating operations are the alternative or in inoperable patients.     

Desmoplastic fibroma of the cranium: case report and review of the literature

OBJECTIVE AND IMPORTANCE: Desmoplastic fibroma is a benign bone tumor that can be locally aggressive. It usually occurs in the long bones and mandible. We report on a patient with a desmoplastic fibroma arising in the temporal bone and review previously published cases of desmoplastic fibroma originating within the cranium. CLINICAL PRESENTATION: A 43-year-old woman presented with a 12-year history of progressively worsening head asymmetry. Magnetic resonance imaging and computed tomography demonstrated a mass originating from the bone and involving the adjacent soft tissues. INTERVENTION: A temporal parietal craniectomy was performed with excision of a large tumor involving the bone. An acrylic cranioplasty was used to replace the bone. Pathological examination of the lesion identified desmoplastic fibroma of the cranium. After surgery, the patient's cranial asymmetry was corrected. CONCLUSION: Desmoplastic fibroma of the cranium is rare. Surgical resection is the treatment of choice.     

Desmoplastic fibroma of parietal bone simulating eosinophilic granuloma. Case report

Desmoplastic fibroma is a distinctive and rare neoplasm of bone. Only one previous example has been reported in the calvaria. The diagnostic and surgical aspects of a case of desmoplastic fibroma of the skull that radiographically simulated eosinophilic granuloma are reported.     

Desmoplastic fibroblastoma of the thigh. A case report

Desmoplastic fibroblastoma (DF) is an extremely rare benign soft tissue tumor, prevalent in adult men, mostly arising in deep regions of extremities. The tumor presents with a slowly growing and no recurrence or metastases after surgical excision. Histologically, DF is characterized by a collagenous stroma that contains spindle- and stellated-shaped fibroblastic cells positive for vimentin. Differential diagnosis with locally aggressive soft tissue tumors could be difficult. This case report deals with the clinical pathological and immunoistochemical features of a DF of the left thigh in a 63-years old man.     

Desmoplastic fibroma of bone. A report of eight cases and review of the literature

Desmoplastic fibroma of bone is a rare benign tumor consisting of thin, wavy fibroblasts set in an abundant matrix of collagen fibers. At times it is difficult to distinguish desmoplastic fibroma from other fibrous lesions, especially low-grade fibrosarcomas. Fewer than eight cases have been previously reported. We have reviewed the diagnostic and therapeutic findings of eighty additional cases. Six patients had the lesions located in an extremity and two had an axial lesion. The average age of the patients was twenty-five years (range, twelve to fifty-six years) and all of the patients had more than two years of follow-up (range, two to seventeen years). The radiographic findings in all but one patient were of a purely lytic, honeycombed lesion that often widened the bone, and was metaphyseal in long bones. The tumor replaced the medullary cavity with a grayish-white, rubbery to firm tissue that was often, but not always, contained by a rim of periosteal reactive bone. Histologically, the features were: (1) prominent loose bundles of fibrous tissue composed of slim, spindle-shaped fibroblasts with wavy, elongated nuclei; (2) variable amounts of bands of collagen fibers; and (3) absence of mitoses or atypical cells. Areas of metaplastic bone were found only around sites, of pathological fractures. The biology of desmoplastic fibroma is different from that of other benign fibrous lesions in that the lesion is very destructive locally and often recurs after incomplete excision. It is also distinguished from low-grade malignant lesions (for example, fibrosarcoma) in that metastases have never been reported. In our series an intralesional excision was initially performed in six of the eight patients and a marginal resection, in two. There were four recurrences, treated by a marginal resection in two patients and repeat curettage in one. The recurrence in the fourth patient required an amputation above the knee after two additional intralesional procedures had been unsuccessful. Wide or marginal resection appears to be the treatment of choice when the lesion is located in a site that can be resected without significant loss of function. In other areas, an attempt at curettage, instillation of phenol, and bone-grafting seems to be warranted, resorting to more radical procedures only if this fails to control local disease.