Massive residual dental cyst: Case report

A case report is presented of a massive residual dental cyst that involved over half an edentulous mandible. Presentation, diagnosis and management of the massive cyst is discussed.     

Glandular odontogenic cyst (sialo-odontogenic cyst): A case report

A case of a rare cyst of the jaw bones is reported. This lesion appears to be a new entity and has been named glandular odontogenic cyst (GOC) or sialo-odontogenic cyst. The clinical and histological features and the differential diagnosis are discussed.     

Glandular odontogenic cyst: a report of four cases

A glandular odontogenic cyst is a developmental cyst that is a clinically rare and histopathologically unusual type of odontogenic cyst. In this article, we describe four cases of glandular odontogenic cyst. Glandular odontogenic cyst was defined as a well-defined unilocular lesion on panoramic radiographs and multidetector computed tomography. Furthermore, the connection of the cyst to the periodontal tissue was one of the common features of the four cases. The results of the present study indicate the clinical and imaging features of glandular odontogenic cyst.     

Coexistence of lymphoepithelial and epidermoid cysts on the floor of the mouth: report of a case

Lymphoepithelial and epidermoid cysts in the oral cavity are uncommon. The coexistence of lymphoepithelial and epidermoid cysts in the oral cavity is extremely rare. Only one case of lymphoepithelial cyst associated with two epidermoid cysts on the floor of the mouth has been reported in the literature and the present report describes a second case where a lymphoepithelial cyst coexisted with an epidermoid cyst on the floor of the mouth. It is likely an accidental trauma that was accompanied by inflammation produced the development of implantation-keratinizing epidermoid and lymphoepithelial cysts.     

Mandibular buccal bifurcation cyst: enucleation without extraction

The mandibular buccal bifurcation cyst (MBBC) is a cystic lesion, which occurs on the buccal surface of the permanent mandibular first molar in children around 6-8 years old. Treatment of the cyst has been controversial: extraction of the involved tooth and enucleation of the cyst, or only enucleation, without extraction. The aim of this article is to familiarize oral and maxillofacial surgeons with this entity and the appropriate treatment approach. The diagnostic features of MBBC are described and the treatment approach in five patients with a total of seven cysts is presented. Two cases were identified in identical twins. Enucleation of the cyst without extraction of the involved tooth is the treatment of choice when the available data and experience in treating MBBC are considered.     

颈上部支气管源性囊肿1例报告及文献复习

报告1例颈上部支气管源性囊肿,结合文献资料分析其临床表现、影像学、细胞学及病理学特征,为临床诊断及鉴别诊断提供参考。支气管源性囊肿发生在颈上部者非常少见,其症状和体征与常见的颈部肿物相似,鉴别较为困难,术前易误诊为鳃裂囊肿、淋巴管畸形、舌下腺囊肿等。临床上需完善检查、综合判断、妥善处理。     

Eruption cyst in the adult--a case report

A case of eruption cyst in the right maxilla of a 40-year-old female is reported.     

Nasolabial Cyst: Review of Literature and a Case Report

The nasolabial cyst is a rare non-odontogenic cyst that develops within the skin adjacent to the ala of nose around the uppermost portion of the nasolabial crease; its pathogenesis is uncertain. This lesion grows slowly and measures between 1.5 to 3.0 cm; it is characterized clinically by a floating tumefaction in the nasolabial sulcus, which elevates the upper lip. The diagnosis is essentially based on the clinical findings. Bi—digital palpation revealed fluctulance between the floor of nasal vestibule and the gingivobuccal sulcus, which helps to confirm the diagnosis. This paper reports a case of a 35-year-old female patient that presented a soft swelling in the right ala of the nose; the clinical features suggested a nasolabial cyst. Complete surgical excision of the cyst was done under local anesthesia and the diagnosis was confirmed by histopathology. In spite of the low occurrence of nasolabial cysts, it is important to recognize the clinical characteristics of this lesion. The purpose of this paper is to review the literature and discuss the histopathology, etiology and different treatment options of this condition.     

Non-neoplastic jaw cysts: a 30-year epidemiological study of 2150 cases in the Italian population

Non-neoplastic jaw cyst (NJC) is one of the most common lesions in oral cavity, but there are only few detailed and extended epidemiological data based on the 2017 WHO classification. The aim of this study was to perform an epidemiological analysis of all NJCs treated from 1990 to 2019 at the Marche Polytechnic University, and to compare these data with those published in the literature. This retrospective study considered 2060 patients treated from 1990 to 2019. The NJCs were classified according to the 2017 WHO classification, and the main clinicopathological variables were analysed (sex, age, diagnosis, site of onset, size, and recurrences). Of 2150 total lesions, there were 2095 primary cysts and 55 recurrences; men are more frequently affected than women (M/F ratio of 1.73:1). The mean age of occurrence was 46.6 years, with a peak of frequency in the fifth decade. The mandible was more frequently involved than the maxilla, with a mean size of 1.9 cm. Radicular cyst was the most frequently diagnosed cyst (56.6%), followed by dentigerous cyst (23.4%) and odontogenic keratocyst (12.9%). This is the first epidemiological study on NJCs in the Italian population according to 2017 WHO classification.     

左颞下窝表皮样囊肿1例报告及文献复习

表皮样囊肿为胚胎发育时期遗留于组织中的上皮发展形成的囊肿,也可由于外伤或手术使上皮细胞植入而形成。颌面部好发于口底、颏下、眼睑、额、鼻、眶外侧及耳下等部位,而发生于颞下窝者少见。作者报道1例典型病例,并对其临床表现、诊断和治疗进行了讨论。     

Review on 209 Congenital Cysts of the Floor of the Mouth

目的：比较1980—2005年在武汉大学口腔医院治疗的89位中国病人和在约旦医院治疗的120位病人三型口底囊肿的临床特点。方法：回顾性分析皮样囊肿、表皮样囊肿和畸胎样囊肿患者的年龄、性别、种族，以及比较两组患者的囊肿位置、大小、就诊时间、手术治疗方法和复发率等方面的差别。结果：209例口底囊肿中，93例（44．5％）男性，116例（55．5％）女性。皮样囊肿66例（31．6％）、表皮样囊肿115例（55％）、畸胎样囊肿28例（13．4％）。皮样囊肿、表皮样囊肿多见于头3个10岁年龄组，20-29岁高发，而畸胎样囊肿高好发于10岁以前。约90％的患者无自觉症状。发病后6个月以内就诊者，第1组（43．8％）明显少于第2组（80％）。这些先天性囊肿常发生在口底中部。就诊时第1组中囊肿直径大于3cm者达48．3％，而第2组中囊肿直径大于3cm者仅11．7％。第1组中经口外进路切除病变占58．4％，而第2组为41．7％。141例随访病例的术后复发25例，复发率是17．7％。结论：两组口底囊肿有类似的临床特点，其中表皮样囊肿较常见，畸胎样囊肿的发病年龄较小。手术切除不彻底可导致病变复发。     

耳后区进路切除第二鳃裂囊肿8例分析

目的：探讨耳后区进路切除第二鳃裂囊肿的可行性及美容效果。方法：8例第二鳃裂囊肿患者（其中男3例,女5例）,采用耳后区切口进路作病变切除术。结果：全部病变被完整切除,切口愈合良好,无耳大神经和面神经下颌缘支损伤。经平均14.5个月随访,病变无复发,瘢痕隐蔽。结论：耳后区进路切除第二鳃裂囊肿方法可行,并可获得理想的美容效果。     

囊肿塞子在颌骨囊肿开窗减压术中的应用

目的 探讨囊肿塞子在颌骨囊肿开窗减压术中的应用价值。 方法 选取2008年至今巨大颌骨囊肿和替牙期囊肿患者共122例,行开窗减压术后制作125件囊肿塞子（1例多发囊肿）,观察效果。 结果 本组病例中100例患者囊腔在1~2年内闭合,包含23例9~12岁儿童,22例患者遗留一小囊腔,需二次手术,随访2年无一例复发。下颌愈合时间较上颌愈合时间短,所有混合牙列期患者恒牙均正常萌出,膨出的面型恢复正常。 结论 颌骨囊肿开窗减压术后佩戴囊肿塞子可以有效地阻止食物进入囊腔,引流出囊液。     

Ameloblastomatous calcifying odontogenic cyst: a rare histologic variant

Calcifying odontogenic cyst (COC) is an uncommon developmental odontogenic cyst first described by Gorlin in 1962. It is considered as extremely rare and accounts for only 1% of jaw cysts reported. Because of its diverse histopathology, there has always been confusion about its nature as a cyst, neoplasm or hamartoma. Several subclassifications have been proposed. Here, we present a case of calcifying odontogenic cyst with ameloblastic proliferation - an extremely rare histologic variant. The classical histologic features of the lining epithelium in the form of cords and presence of characteristic ghost cells were seen along with ameloblastomatous proliferations. Ameloblastomatous COC microscopically resembles unicystic ameloblastoma except for the ghost cells and calcifications within the proliferative epithelium. The nature of the COC is controversial. The case is presented here for its rarity, and difference between ameloblastomatous COC and ameloblastoma ex COC has been emphasized.     

Cytokine and chemokine levels in radicular and residual cyst fluids

Background:  Cytokines were thought to play an important role for the expansion of odontogenic cysts. The purpose of this study was to evaluate the cytokine and chemokine levels of radicular and residual cyst fluids.
Methods:  Cyst fluids were aspirated from 21 patients (11 radicular and 10 residual cysts) and the levels of interleukin-1 alpha (IL-1α), tumor necrosis factor-alpha (TNF-α), monocyte chemotactic protein-1 (MCP-1), and regulated upon activation normal T cell expressed and secreted (RANTES) were determined by ELISA using commercially available kits.
Results:  Both radicular and residual cyst fluids contained IL-1α, TNF-α, MCP-1, and RANTES, concentrations of which were significantly higher in the radicular cyst fluids than those in the residual cysts ( P  < 0.001 for IL-1α, TNF-α, and RANTES; P  < 0.01 for MCP-1). Compared to the other mediators, the concentration of IL-1α was found to be highest in both of the cyst fluids. In addition, positive correlations were found between IL-1α, TNF-α, MCP-1, and RANTES in radicular and residual cyst fluids.
Conclusion:  If the radicular cyst is inadvertently left behind following tooth extraction, some degree of inflammation may carry on. Residual cysts, although to a lesser extend than radicular cysts, have the potential to expand.     

超声骨刀在根尖囊肿刮治术中的应用效果观察

目的：评价超声骨刀在根尖囊肿刮治术中的应用效果。方法：应用超声骨刀对29例根尖囊肿行囊肿刮治术,术后观察病变区的变化。结果：29例在观察期内预后均良好。结论：超声骨刀应用于根尖囊肿刮治术可获得很好的疗效。     

牙源性囊肿及成釉细胞瘤细胞核DNA定量研究

目的　探讨角化囊肿、根尖囊肿、含牙囊肿和成釉细胞瘤上皮细胞的增殖特点。方法对角化囊肿、根尖囊肿、含牙囊肿上皮基底细胞和棘细胞及成釉细胞瘤外周柱状细胞和中央星网状细胞进行细胞核DNA含量测定 ,结合倍体和直方图分析。结果　牙源性角化囊肿及成釉细胞瘤细胞DNA增殖倍体含量较高 ,细胞增殖相对活跃。角化囊肿棘细胞增殖较基底细胞活跃。根尖囊肿DNA含量高与炎症刺激细胞增生有关 ,含牙囊肿细胞增殖不活跃。结论　细胞增殖活跃可能是牙源性角化囊肿及成釉细胞瘤具有局部侵袭性生长行为的生物学基础     

舌下腺囊肿456例临床病理分析

目的：对舌下腺囊肿临床病理资料进行回顾性研究，评价手术方式与疗效的关系，分析并发症的原因。方法：在全麻或局麻下经口内进路或颌下进路或口内联合颌下进路行舌下腺及囊肿摘除术，部分患者行袋形缝合术；术后标本行组织病理观察。结果：312例舌下型舌下腺囊肿经口内行舌下腺及囊肿摘除术，13例复发，复发率为4．17％；6例行袋形缝合术，5例复发，复发率为83．33％；108例口外型分别经口内、颌下进路行舌下腺及囊肿摘除术，其复发率各为1.43％、56％；而经颌下联合口内进路治疗的病例无复发；40例混合型经口内施术，治愈率达100％。包括术后复发，共有57例发生术中术后并发症。病理切片镜下观，447例中257例(57．5％)囊肿有纤维囊壁，但只有5例有部分上皮衬里，190例(42．5％)无明显囊壁。结论：舌下腺囊肿的囊壁无上皮衬里，完整摘除舌下腺是治愈的关键。     

平阳霉素联合地塞米松注射治疗舌下腺囊肿的疗效观察

目的：总结平阳霉素、地塞米松注射治疗舌下腺囊肿的疗效及优点。方法：收集1995年1月至2002年12月，用平阳霉素联合地塞米松注射治疗舌下腺囊肿215例。结果：经6～24个月随访，治愈197例(91．63％)，基本治愈11例(5．12％)，有效7例(3．25％)。治愈和基本治愈率为96．75％，有效率为100％。结论：平阳霉素联合地塞米松注射治疗舌下腺囊肿，具有疗程短，疗效高，痛苦小，费用低等优点，值得临床选择应用。