两种非球面衍射多焦点人工晶状体植入术后视觉质量评价

目的:综合评价非球面AcrySof ReSTOR+4D和非球面AcrySof ReSTOR+3D两种多焦点IOL植入术后患者的视觉质量,并探讨其相关影响因素。方法:白内障患者40例80眼,随机分为两组。A组:非球面AcrySof ReSTOR+3D(SN6AD1)IOL植入组;B组:非球面AcrySof ReSTOR+4D(SN6AD3)IOL植入组,其中A组为实验组,B组为对照组。术后1d;1wk;1,3mo行常规检查,并检查术眼裸眼远(UCDVA)、中(UCIVA)、近视力(UCNVA)。术后3mo检查最佳矫正远(BCDVA)、近视力(BCNVA),以及最佳矫正远视力下的近(DCNVA)、中视力(DCIVA);检查对比敏感度及波前像差;绘制离焦曲线,并进行主观问卷调查评分。结果:术后1d;1wk;1,3mo,两组的UCDVA差异均无统计学意义(P>0.05),UCIVA的差异均有统计学意义(P<0.05)。UCNVA在术后第1d,两组间的差异有统计学意义(P<0.05),而在其余时间段,两组间差异无统计学意义(P>0.05)。术后3mo时,两组的BCDVA,BCNVA,DCNVA,DCIVA差异均无统计学意义(P>0.05);两组间总像差、高阶像差、球差间,差异无统计学意义(P>0.05);在各个视角水平有/无眩光下,对比敏感度差异无统计学意义(P>0.05)。离焦曲线显示:B组在+0.0D和-3.0D处形成两个焦点,而A组不仅在+0.0D和-2.5D处形成两个焦点,而且在-2.0～-2.5D之间可形成一个平台期。问卷调查显示:两组患者视远、视近的满意度较高;而视中距离时,A组患者满意度明显高于B组。两组患者术后视觉不良症状发生率,差异无统计学意义(t=-0.87,P>0.05)。结论:非球面AcrySof ReSTOR+3D IOL植入术后,为患者提供了良好的远、中、近全程视力,尤其是中距离视力较非球面AcrySof ReSTOR+4D IOL有了显著的改善,且没有明显的视觉干扰,提高了患者的视觉和生活质量。     

Postoperative optical aberrations in eyes implanted with AcrySof spherical and aspheric intraocular lenses

PURPOSE: To evaluate and compare optical and visual quality of eyes implanted with spherical and aspheric intraocular lenses (IOLs). METHODS: Twenty eyes of 17 patients were implanted with the AcrySof Natural IQ aspheric IOL (SN60WF) and 20 eyes of 15 patients were implanted with the AcrySof Natural spherical IOL (SN60AT). Photopic monocular distance best spectacle-corrected visual acuity (BSCVA) was recorded at 6 months postoperatively. Corneal aberrations were measured with the CSO Eyetop topographer, and ocular aberrations were measured with a Hartmann-Shack aberrometer for a 6-mm pupil. Ocular spherical aberration was computed for different pupil diameters (3, 4, 5, and 6 mm). RESULTS: No statistically significant differences were found between the BSCVA of the AcrySof IQ IOL (0.023 +/- 0.004 logMAR) and AcrySof Natural IOL (0.031 +/- 0.003 logMAR) (P = .15). The corneal higher order aberrations showed no statistically significant differences between groups (P > .1). However, spherical aberration and higher order ocular aberrations in the AcrySof IQ eyes were lower than eyes implanted with the AcrySof Natural IOL (P < .01). A statistically significant increase in the spherical aberration coefficient with pupil diameter was found only for the spherical IOL group (P = .0023). Statistically significant differences in the spherical aberration coefficient were found between groups at all pupil diameters (P < .001). CONCLUSIONS: A significant reduction in ocular spherical aberration was noted after AcrySof IQ IOL implantation at all pupil diameters compared to the spherical IOL, although photopic BSCVA between groups remained similar.     

Internal spherical aberration by ray tracing-type aberrometry in multifocal pseudophakic eyes

Purpose

To demonstrate the results of the ray tracing-type aberrometer in measuring spherical aberration (SA) in pseudophakic eyes with monofocal intraocular lens (IOL), aspheric monofocal IOL, or aspheric diffractive multifocal IOL.

Methods

Total, corneal, and internal SA were measured using iTrace at a 6-mm pupil size in 27 eyes of 27 patients implanted with a monofocal spherical IOL (group 1: Natural, SN60AT), 30 eyes of 30 patients implanted with a monofocal aspheric IOL (group 2: IQ, SN60WF), and 30 eyes of 30 patients implanted with a multifocal aspheric IOL (group 3: ReSTOR, SN6AD1) at 3 months after cataract surgery. We compared the internal SAs of these IOLs in pupil sizes of 3, 4, 5, and 6 mm.

Results

There were no demographic statistically significant differences among the groups. The internal SA of group 1 had a positive value. The internal SA of group 2 was −0.175±0.135 μm in 5-mm pupils and −0.227±0.253 μm in 6-mm pupils. The internal SA of group 3 was −0.072±0.128 μm in 5-mm pupils and −0.173±0.231 μm in 6-mm pupils.

Conclusion

Measuring internal SA with iTrace yields relatively accurate results in all types of IOLs with adequate pupil sizes.     

非球面AcrySof ReSTOR +3D人工晶状体的临床应用观察

目的:与非球面AcrySof ReSTOR +4D人工晶状体比较,初步观察植入ReSTOR +3D和ReSTOR +4D人工晶状体眼的视功能,以评价非球面AcrySof ReSTOR +3D人工晶状体植入术后的效果。方法:全组36例40眼老年性白内障患者行白内障超声乳化吸除联合人工晶状体植入术,术后3mo检查患者的裸眼远、中(60cm)、近视力(40cm),最佳矫正远视力和中、近视力,对比敏感度,进行生活问卷。结果:两组术后的远视力,近视力均无统计学差异(P>0.05),植入非球面AcrySof ReSTOR +3D人工晶状体组平均中距离视力比植入非球面AcrySof ReSTOR +4D人工晶状体组有显著提高(P<0.01)。结论:非球面AcrySof ReSTOR +3D人工晶状体在远、中、近距离均能提供良好的视力,尤其是中距离视力比+4D有了显著改善,有极高的患者满意度和脱镜率。     

Prospective visual evaluation of apodized diffractive intraocular lenses

PURPOSE: To evaluate distance, intermediate, and near visual performance in patients who had multifocal apodized diffractive intraocular lens (IOL) implantation. SETTING: Fernández-Vega Ophthalmological Institute, Oviedo, Spain. METHODS: The best corrected distance visual acuity, best distance-corrected near visual acuity, intermediate visual acuity, distance contrast sensitivity under photopic and mesopic conditions, and patient satisfaction were measured in 325 patients and 335 patients who had bilateral implantation of the model SA60D3 IOL (AcrySof ReSTOR, Alcon) and model SN60D3 IOL (AcrySof Natural ReSTOR), respectively. RESULTS: At the 6-month postoperative visit, binocular best corrected distance acuity with the ReSTOR IOL and the Natural ReSTOR IOL was 0.034 logMAR+/-0.004 (SD) and 0.019+/-0.020 logMAR, respectively (approximately 20/20). Binocular best distance-corrected near acuity was 0.011+/-0.012 logMAR and 0.035+/-0.013 logMAR, respectively (approximately 20/20). Intermediate visual acuity with both IOL models worsened significantly as a function of the distance of the test (P<.01). Photopic contrast sensitivity was within the standard normal range with both IOLs. Under mesopic conditions, contrast sensitivity with both IOLs was comparable to that with monofocal IOLs and lower, particularly at higher spatial frequencies, than under photopic conditions. No statistically significant differences in visual acuity or photopic and mesopic contrast sensitivity were found between the 2 IOL models (P>.1). A patient satisfaction questionnaire showed that both IOLs performed well and were comparable in satisfaction regarding distance, intermediate, and near activities under different lighting conditions. CONCLUSIONS: The AcrySof ReSTOR IOL and AcrySof Natural ReSTOR IOL provided good visual performance at distance and near under photopic and mesopic conditions. Intermediate vision with both models was reduced compared with distance and near vision.     

Corneal spherical aberration and its impact on choosing an intraocular lens for cataract surgery

Purpose

To analyze the post operative results of targeting zero spherical aberration by selecting the best-fit aspheric intraocular lens (IOL), based on preoperative corneal spherical aberration of patients with phacoemulsification surgery.

Setting

AlHokama Eye Specialist Center, Riyadh, Saudi Arabia.

Period

From the 1st of October 2012 until the 10th of April 2013.

Methods

Fifty-three eyes, were subjected to phacoemulsification cataract surgery and divided into two groups, 34 eyes were implanted with aspheric IOLs based on their corneal spherical aberration targeting post operative zero total spherical aberration, whereas 19 eyes were implanted with neutral aspheric IOLs regardless of their corneal spherical aberrations (CSAs). As a pre and post routine examination, patients underwent: slit lamp testing, intraocular pressure (IOP) measuring, fundus examination, best spectacle corrected visual acuity (BSCVA), manifest refraction, pupillometry, axial length, contrast sensitivity, and corneal aberration measurement using Pentacam HR (OCULUS, Germany) at the 6-mm optical zone. Post operatively, visual function questionnaire (VF-14) was asked to all patients.

Results

Fifty-three eyes of 45 patients, whose age ranged from 45 to 90 years old, were available for analysis, the selected group was implanted with: Tecnis ZA9003 or ZCB00 (Abbott Medical Optics) IOLs in 17 eyes with corneal spherical aberration of more than 0.27 μm, AcrySof IQ SN60WF (Alcon Laboratories Inc.) IOLs were implanted in 4 eyes with CSA = (0.2–0.27) μm, and Rayner 970C, 920H or 620H IOLs with spherical aberration (SA) = 0 in 13 eyes with CSA less than 0.20 μm. The other group of 19 eyes was implanted with aspheric IOLs that have zero spherical aberration (Rayner 970C or 920H) regardless of their CSA. Root mean square (RMS) of total corneal aberration positively correlates to the pupil diameter (P = 0.0031, r = 0.3989). A low negative correlation was found between the corneal spherical aberration of the fourth ordered (Z40) and the axial length (r = −0.2009, P = 0.1492). There was no significant difference between the selected and non-selected group in contrast sensitivity, best spectacle corrected visual acuity, and visual satisfaction (P = 0.5316, P = 0.3919, P = 0.7667).

Conclusion

Customized selection of aspheric IOLs based on the eyes’ corneal spherical aberration has no significant importance comparing their results with the non-selected group.     

In vitro optical performance of a new aberration-free intraocular lens

Purpose

To assess the optical performance of the new EnVista intraocular lens (IOL).

Materials and methods

Four aspheric IOLs were evaluated; the new EnVista is one amoung them. This IOL, similarly to the Z-Flex HB and the Bi-Flex 1.8 667AB ones, has a neutral aspheric design, whereas the fourth IOL under test (AcrySof IQ IOL SN60WF) presents a negative spherical aberration (SA). The IOL''s aberration patterns were measured in vitro, by setting them up on an optical bench. From these aberration-pattern data, the modulation transfer function (MTF), the average modulation values, and the points spread function (PSF) were calculated. Furthermore, in order to assess the potential optical quality that these IOLs would yield once they are implanted, an average corneal-aberration pattern was juxtaposed to the in-vitro profiles and the same parameters were calculated again.

Results

For the IOL-only scenario (ie, without including the corneal factor), it was the EnVista IOL, which is aberration-free that showed the higher MTF, PSF values. This was followed by the other two aberration-free IOL models. However, when the effect of an average corneal pattern was also taken into consideration, the AcrySof IQ IOL SN60WF always outperformed the other neutral-asphericity IOLs.

Conclusions

The in-vitro optical performance of the EnVista IOL was good, but it decreases substantially in a whole-eye scenario, when the wavefront profile of an average cornea is added. Other designs with different degrees of SA should be considered for this IOL in order to surpass these results.     

双通道视觉质量分析系统在球面和非球面人工晶状体眼视觉质量评价中的应用

目的　使用双通道视觉质量分析系统（optical quality analysis system,OQAS）对球面和不同球差值非球面人工晶状体（intraocular lens,IOL）眼视觉质量进行评估。方法　选择白内障超声乳化及IOL植入术的年龄相关性白内障患者227例（349眼）分5组，分别植入Bausch & Lomb球面IOL Akreos Adapt、AMO球面IOL Sensar AR40E、Bausch & Lomb非球面IOL Akreos Adapt AO（球差值0 μm）、Alcon非球面IOL Acrysof IQ SN60WF（球差值-0.20 μm）、AMO非球面IOL Tecnis ZCB00（球差值-0.27 μm）。术后3个月采用双通道客观视觉质量分析系统（OQASTMⅡ）、KR-1W像差仪进行检查。比较各组客观散射指数（objective scatter index,OSI）、调制传递函数截止频率（MTF cut off）、斯特列尔比（Strehl ratio,SR）、模拟对比度视力（OV100%、OV20%、OV9%）波前像差。结果　术后3个月，5组间裸眼视力（uncorrected visual acuity,UCVA）、最佳矫正视力（best corrected visual acuity,BCVA）、等效球镜（spherical corrected,SE）比较差异均无统计学意义（均为P＞0.05）。5组间角膜高阶像差差异均无统计学意义（均为P＞0.05）；4 mm瞳孔眼内球面像差（spherical aberration,SA）、全眼SA差异均有统计学意义（均为P＜0.05）；6 mm瞳孔眼内和全眼总高阶像差（total higher order aberration,tHOA）、SA差异均有统计学意义（均为P＜0.05）。5组间OQAS参数差异均有统计学意义（均为P<0.05）。OSI:ZCB00组均优于AK组、AR40E组、AO组（均为P＜0.05）；MTF cut off:SN60WF组、ZCB00组均优于AK组、AR40E组（均为P＜0.05）；SR:SN60WF组、ZCB00组优于AK组（均为P＜0.05）；OV100%:SN60WF组、ZCB00组均优于AK组、AR40E组（均为P＜0.05）；OV20%:SN60WF组均优于AK组、AR40E组、AO组，ZCB00组均优于AK组（均为P＜0.05）；OV9%:SN60WF组、ZCB00组均优于AK组、AR40E组（均为P＜0.05）。其余组间各指标差异均无统计学意义（均为P>0.05）。结论　非球面IOL眼视觉质量优于球面IOL眼；负球差非球面IOL AMO ZCB00和Alcon SN60WF优于零球差非球面IOL Bausch & Lomb Akreos AO；OQAS可以全面、客观地评价白内障术后IOL眼的视觉质量。     

Optical performance after bilateral implantation of apodized aspheric diffractive multifocal intraocular lenses with +3.00‐D addition power

Purpose: To determine whether bilateral implantation of an aspheric apodized diffractive multifocal intraocular lens (IOL) with +3.00 diopters (D) results in optical adverse effects compared with an aspheric monofocal IOL. Methods: In a prospective, randomized study of 204 eyes (102 patients) with bilateral implantation of an AcrySof ReSTOR SN6AD1 IOL or an AcrySof IQ SN60WF IOL, binocular uncorrected (UDVA) and corrected distance visual acuities (CDVA), uncorrected (UIVA) and distance‐corrected intermediate visual acuities (DCIVA), uncorrected (UNVA) and distance‐corrected near visual acuities (DCNVA), defocus curve, intraocular straylight, wavefront aberrations, modulation transfer functions (MTF) and patient questionnaires were evaluated postoperatively. Results: Both groups resulted in similar UDVA and CDVA (p > 0.05), whereas the multifocal IOL group performed significantly better UIVA and DCIVA at 50, 60 cm, and better UNVA and DCNVA at 40 cm (p ≤ 0.001). Higher intraocular straylight was obtained in the multifocal IOL group (p = 0.016). Total, higher‐order, spherical and coma aberrations performed similar in both groups (p > 0.05). MTF was lower in the multifocal IOL group than in the monofocal IOL group with 3.0‐mm pupils at 5 and 10 cycles per degree (cpd). Although patients in the multifocal IOL group complained more glare/flare, problems with night vision, and halos, they reported excellent spectacle independence, and high satisfaction. Conclusions: Compared with the AcrySof IQ IOL, the ReSTOR SN6AD1 IOL provided excellent visual outcomes, satisfactory spectacle independence without compromising wavefront aberrations; however, optical adverse effects with respect to higher intraocular straylight and lower MTF at lower spatial frequency were demonstrated.     

非球面多焦点IOL眼的对比敏感度和拟调节力分析

目的评价白内障超声乳化摘出联合非球面衍射型多焦点人工晶状体植入术后患者的视觉质量和拟调节力。方法 54例(75眼)于我院行白内障超声乳化摘出联合人工晶状体植入术的患者进行分组,其中SN6AD3组17例(25眼)植入非球面多焦点人工晶状体Acrysof ReSTOR SN6AD3,SN60D3组18例(25眼)患者植入多焦点人工晶状体Acrysof ReSTOR SN60D3,SN60WF组19例(25眼)植入单焦点非球面人工晶状体Acrysof SN60WF。术后3个月时检查裸眼及矫正远视力、裸眼近视力、最佳矫正远视力下的近视力、拟调节力、对比敏感度,并比较3组患者脱近用镜率。结果术后3个月,三组患者裸眼远视力和最佳矫正远视力差异均无统计学意义(均为P>0.05);SN60D3组和SN6AD3组术后裸眼近视力(0.205±0.111、0.192±0.120)和最佳矫正远视力下的近视力(0.212±0.114、0.250±0.130)明显优于SN60WF组(0.661±0.278与0.661±0.278;均为P<0.01),SN60D3组和SN6AD3组间差异无统计学意义(P>0.05)。眩光及无眩光时,在各空间频率下SN60WF组和SN6AD3组对比敏感度均大于SN60D3组。SN6AD3组调节幅度为(0.925±0.549)D,SN60D3组为(0.964±0.582)D,SN60WF组为(0.390±0.235)D,SN6AD3组与SN60D3组间差异无统计学意义(P=0.993),SN6AD3组与SN60D3组的调节幅度均高于SN60WF组(P<0.01)。SN6AD3组脱近用镜率80%、SN60D3组72%,两组均优于SN60WF组(24%,均为P<0.01)。结论 ReSTOR非球面衍射型多焦点人工晶状体SN6AD3能提供良好的远、近视力,植入后术眼具有较SN60D3更高的对比敏感度,能有效改善白内障患者术后的视觉质量。     

Die asphärische Blaulichtfilter-IOL AcrySof IQ im Vergleich mit der AcrySof SA60AT

Background

The aspheric optic design of intraocular lenses (IOL) aims to minimize postoperative ocular spherical aberration (SA). The effect of a standardized IOL asphericity depends on IOL power, pupil diameter, and corneal asphericity. The impact of these factors was investigated in a comparative study.

Material and methods

In a prospective study, 70 eyes with the aspheric blue light filter IOL AcrySof IQ (Alcon) were compared to 36 eyes with the conventional AcrySof SA60AT (Alcon). Six weeks after uneventful phacoemulsification the following parameters were assessed: visual acuity, higher order aberrations, pupil diameter, and corneal asphericity.

Results

The comparison of 42 eyes in a normal dioptric range with the IQ IOL (22.4±2.0 D) to 20 eyes with the control lens of similar IOL power (22.0±2.7 D) showed no different visual outcome. For a 5-mm pupil SA was calculated at 0.04 (±0.05) µm for the IQ IOL and 0.20 (±0.06) µm for the AcrySof SA60AT. Also for a 4-mm pupil SA was significantly lower in eyes with the IQ lens. A separate evaluation of 28 eyes which needed very high or low IOL power revealed a similar postoperative SA for the IQ IOL. The greatest difference of SA between the two IOLs was found in hyperopic eyes with higher IOL power. The corneal asphericity (Q value) showed significant correlation to postoperative ocular SA.

Conclusions

The aspheric AcrySof IQ reduces postoperative SA significantly compared to a conventional IOL even with smaller pupils and independent of IOL power. The assessment of corneal asphericity enables an individual estimation of postoperative SA.     

Visual acuity and contrast sensitivity comparison between Tecnis and AcrySof SA60AT intraocular lenses: A multicenter randomized study

PURPOSE: To evaluate best corrected visual acuity (BCVA) and photopic and mesopic contrast sensitivity in pseudophakic patients implanted either with the aspheric intraocular lens (IOL) designed to correct for corneal spherical aberration or with a conventional IOL. SETTING: Three surgical centers participated this prospective randomized masked comparative study. METHODS: Thirty eyes of 30 patients after aspheric lens implantation (Pfizer/Pharmacia Tecnis Z9000) were compared with 30 eyes of 30 age-matched patients after conventional lens implantation (Alcon AcrySof SA60AT). Two to three months after surgery, best spectacle corrected distance visual acuity was measured using the Early Treatment Diabetic Retinopathy Study chart. Contrast sensitivity was measured by sinusoidal grating charts for distance at photopic (85 cd/m(2)) and mesopic (6 cd/m(2)) luminance level with optical correction in place. Tested spatial frequencies were 1.5, 3, 6, 12, and 18 cycles per degree (cpd). RESULTS: The mean BCVA was -0.053 +/- 0.044 logMAR in eyes with the aspheric Tecnis IOL and 0.006 +/- 0.059 logMAR in eyes with the conventional AcrySof IOL (P=.0001). Eyes with the aspheric IOL showed better contrast sensitivity at spatial frequencies of 3 cpd (P<.05) and 6, 12, and 18 cpd (P<.01) in photopic and in mesopic conditions. Peak improvement occurred at 18 cpd and was 36% (0.29 log units) in photopic and 54% (0.27 log units) in mesopic conditions. CONCLUSIONS: The aspheric Tecnis IOL yielded better BCVA and better distance contrast sensitivity than the conventional IOL. The differences were clinically significant for higher spatial frequencies. The results give some suggestions for further studies.     

黄色非球面人工晶状体植入术后视觉质量的临床分析

目的 观察老年性白内障患者植入黄色非球面人工晶状体AcrySof IQ术后对比敏感度和眩光敏感度.方法 前瞻性临床对照研究.56例(56只眼)老年性白内障患者,随机分为三组,分别植入非球面人工晶状体AerySof IQ(SN60wF)及球面人工晶状体Acrysof Natural(SN60AT)、Acrysof (SA60AT).术后2月行最佳矫正视力、像差及对比敏感度检查.结果 三组患者术后最佳矫正视力≥20/30.IQ组与球面晶状体组比较,球差均显著性减少(P<0.05),高阶像差及彗差无统计学意义(P0.05).在非眩光状态下,低频时IQ组的对比敏感度(10g值)显著高于球面晶状体组(P<0.05),中频2.5deg时IQ组的对比敏感度显著高于SA60AT组(P<0.05).在眩光状态下,低频时IQ组的对比敏感度也显著高于球面晶状体组(SN60AT组:P<0.01,SA60AT组:6.3degrees P<0.01,4.0degrees P<0.05).结论 非球面人工晶状体可以减少球面像差,提高低频尤其是眩光状态下的对比敏感度从而获得更好的视觉质量.滤蓝光晶状体与普通晶状体比较对比敏感度差异无统计学意义,不能明显改善视功能.     

黄色非球面人工晶状体植入术后视觉质量的临床分析

目的 观察老年性白内障患者植入黄色非球面人工晶状体AcrySof IQ术后对比敏感度和眩光敏感度.方法 前瞻性临床对照研究.56例(56只眼)老年性白内障患者,随机分为三组,分别植入非球面人工晶状体AerySof IQ(SN60wF)及球面人工晶状体Acrysof Natural(SN60AT)、Acrysof (SA60AT).术后2月行最佳矫正视力、像差及对比敏感度检查.结果 三组患者术后最佳矫正视力≥20/30.IQ组与球面晶状体组比较,球差均显著性减少(P<0.05),高阶像差及彗差无统计学意义(P0.05).在非眩光状态下,低频时IQ组的对比敏感度(10g值)显著高于球面晶状体组(P<0.05),中频2.5deg时IQ组的对比敏感度显著高于SA60AT组(P<0.05).在眩光状态下,低频时IQ组的对比敏感度也显著高于球面晶状体组(SN60AT组:P<0.01,SA60AT组:6.3degrees P<0.01,4.0degrees P<0.05).结论 非球面人工晶状体可以减少球面像差,提高低频尤其是眩光状态下的对比敏感度从而获得更好的视觉质量.滤蓝光晶状体与普通晶状体比较对比敏感度差异无统计学意义,不能明显改善视功能.     

黄色非球面人工晶状体植入术后视觉质量的临床分析

目的 观察老年性白内障患者植入黄色非球面人工晶状体AcrySof IQ术后对比敏感度和眩光敏感度.方法 前瞻性临床对照研究.56例(56只眼)老年性白内障患者,随机分为三组,分别植入非球面人工晶状体AerySof IQ(SN60wF)及球面人工晶状体Acrysof Natural(SN60AT)、Acrysof (SA60AT).术后2月行最佳矫正视力、像差及对比敏感度检查.结果 三组患者术后最佳矫正视力≥20/30.IQ组与球面晶状体组比较,球差均显著性减少(P<0.05),高阶像差及彗差无统计学意义(P0.05).在非眩光状态下,低频时IQ组的对比敏感度(10g值)显著高于球面晶状体组(P<0.05),中频2.5deg时IQ组的对比敏感度显著高于SA60AT组(P<0.05).在眩光状态下,低频时IQ组的对比敏感度也显著高于球面晶状体组(SN60AT组:P<0.01,SA60AT组:6.3degrees P<0.01,4.0degrees P<0.05).结论 非球面人工晶状体可以减少球面像差,提高低频尤其是眩光状态下的对比敏感度从而获得更好的视觉质量.滤蓝光晶状体与普通晶状体比较对比敏感度差异无统计学意义,不能明显改善视功能.     

Comparison of higher order aberrations with spherical and aspheric IOLs compared to normal phakic eyes

PURPOSE: To compare higher order aberrations (HOA) in AcrySof SN60AT and Acrysof IQ SN60WF intraocular lenses (IOLs) and natural crystalline lenses in an age-matched population. METHODS: Sixty-nine eyes of 55 patients were examined. Group I included AcrySof spheric lenses, group II AcrySof aspheric lenses, and group III included patients with the natural crystalline lens. The HOA data were obtained with a LADARWave aberrometer (Alcon Inc.). Analysis was based on the RMS of coma, spherical aberrations (SA), and HOA. Statistical comparisons were performed with Kruskal Wallis variance analysis. RESULTS: In the case of coma, there were statistically significant differences between spheric and aspheric AcrySof (p<0.005) and between spheric AcrySof and natural crystalline lenses (p<0.005). The differences between aspheric AcrySof and natural crystalline lens group were not significant (p>0.05). SA were significantly different between spheric and aspheric AcrySof group, and spheric AcrySof and natural crystalline lens group (p<0.005), as well as between aspheric AcrySof and natural crystalline lens group (p<0.05). In case of HOAno significant differences were observed between aspheric AcrySof and natural crystalline lens group (p>0.05), but differences between groups AcrySof spheric and aspheric, and spheric AcrySof and natural crystalline lens, showed high significance (p<0.005). CONCLUSIONS: The AcrySof Natural IQ aspheric model SN60WF IOL did not change the optical quality of vision compared to a healthy population of 60-80 years of age. The AcrySof Natural model SN60AT spherical IOL resulted in higher HOAs relative to both the natural crystalline lens population and eyes after aspheric AcrySof IQ model SN60WF IOL implantation.     

黄色非球面人工晶状体植入术后视觉质量的临床分析

目的 观察老年性白内障患者植入黄色非球面人工晶状体AcrySof IQ术后对比敏感度和眩光敏感度.方法 前瞻性临床对照研究.56例(56只眼)老年性白内障患者,随机分为三组,分别植入非球面人工晶状体AerySof IQ(SN60wF)及球面人工晶状体Acrysof Natural(SN60AT)、Acrysof (SA60AT).术后2月行最佳矫正视力、像差及对比敏感度检查.结果 三组患者术后最佳矫正视力≥20/30.IQ组与球面晶状体组比较,球差均显著性减少(P<0.05),高阶像差及彗差无统计学意义(P0.05).在非眩光状态下,低频时IQ组的对比敏感度(10g值)显著高于球面晶状体组(P<0.05),中频2.5deg时IQ组的对比敏感度显著高于SA60AT组(P<0.05).在眩光状态下,低频时IQ组的对比敏感度也显著高于球面晶状体组(SN60AT组:P<0.01,SA60AT组:6.3degrees P<0.01,4.0degrees P<0.05).结论 非球面人工晶状体可以减少球面像差,提高低频尤其是眩光状态下的对比敏感度从而获得更好的视觉质量.滤蓝光晶状体与普通晶状体比较对比敏感度差异无统计学意义,不能明显改善视功能.     

Contrast sensitivity and higher order aberrations in eyes implanted with AcrySof IQ SN60WF and AcrySof SN60AT intraocular lenses

PURPOSE: To evaluate the efficacy of the aspheric optic of the AcrySof IQ SN60WF intraocular lens (IOL) in decreasing spherical and total higher order aberrations and improving contrast sensitivity after cataract surgery compared to the spheric AcrySof SN60AT. METHODS: Fifty-two eyes of 36 patients were evaluated at the University of Texas Southwestern Medical Center at Dallas 3 to 6 months after phacoemulsification with implantation of the AcrySof IQ SN60WF (27 eyes) or AcrySof SN60AT (25 eyes) IOL. Eyes with previous surgery or ocular pathology were excluded. RESULTS: Eyes implanted with the AcrySof IQ SN60WF had less total higher order and spherical aberrations than AcrySof SN60AT-implanted eyes at pupils of 4 mm (0.14+/-60.06 vs 0.18+/-0.04 microm and -0.01+/-0.03 vs 0.09+/-0.03 microm, respectively), 5 mm (0.24+/-0.07 vs 0.34+/-0.08 microm and 0.03+/-0.02 vs 0.23+/-0.08 microm, respectively), and 6 mm (0.42+/-0.13 vs 0.67+/-0.12 microm and 0.08+/-0.04 and 0.46+/-0.09 microm, respectively), (P<.05 for all), with similar mean coma, trefoil, and 5th order aberrations. AcrySof SN60WF eyes showed better contrast sensitivity than AcrySof SN60AT eyes at 12 and 18 cycles per degree (cpd) under mesopic conditions (1.65+/-0.23 vs 1.51+/-0.25 and 1.22+/-0.21 vs 1.01+/-0.19, respectively), and at 18 cpd under glare (1.12+/-0.30 vs 0.87+/-0.31, respectively) (P<.05). Photopic contrast sensitivity was similar in both groups. The two groups had comparable mean age, axial length, IOL power, and postoperative mesopic and photopic pupil sizes. CONCLUSIONS: Compared to a spheric optic, the aspheric design of the AcrySof IQ SN60WF reduces spherical aberration, especially under larger pupil sizes, and improves mesopic contrast sensitivity at higher frequencies with and without glare.     

黄色非球面人工晶状体植入术后视觉质量的临床分析

目的 观察老年性白内障患者植入黄色非球面人工晶状体AcrySof IQ术后对比敏感度和眩光敏感度.方法 前瞻性临床对照研究.56例(56只眼)老年性白内障患者,随机分为三组,分别植入非球面人工晶状体AerySof IQ(SN60wF)及球面人工晶状体Acrysof Natural(SN60AT)、Acrysof (SA60AT).术后2月行最佳矫正视力、像差及对比敏感度检查.结果 三组患者术后最佳矫正视力≥20/30.IQ组与球面晶状体组比较,球差均显著性减少(P<0.05),高阶像差及彗差无统计学意义(P0.05).在非眩光状态下,低频时IQ组的对比敏感度(10g值)显著高于球面晶状体组(P<0.05),中频2.5deg时IQ组的对比敏感度显著高于SA60AT组(P<0.05).在眩光状态下,低频时IQ组的对比敏感度也显著高于球面晶状体组(SN60AT组:P<0.01,SA60AT组:6.3degrees P<0.01,4.0degrees P<0.05).结论 非球面人工晶状体可以减少球面像差,提高低频尤其是眩光状态下的对比敏感度从而获得更好的视觉质量.滤蓝光晶状体与普通晶状体比较对比敏感度差异无统计学意义,不能明显改善视功能.     

黄色非球面人工晶状体植入术后视觉质量的临床分析

目的 观察老年性白内障患者植入黄色非球面人工晶状体AcrySof IQ术后对比敏感度和眩光敏感度.方法 前瞻性临床对照研究.56例(56只眼)老年性白内障患者,随机分为三组,分别植入非球面人工晶状体AerySof IQ(SN60wF)及球面人工晶状体Acrysof Natural(SN60AT)、Acrysof (SA60AT).术后2月行最佳矫正视力、像差及对比敏感度检查.结果 三组患者术后最佳矫正视力≥20/30.IQ组与球面晶状体组比较,球差均显著性减少(P<0.05),高阶像差及彗差无统计学意义(P0.05).在非眩光状态下,低频时IQ组的对比敏感度(10g值)显著高于球面晶状体组(P<0.05),中频2.5deg时IQ组的对比敏感度显著高于SA60AT组(P<0.05).在眩光状态下,低频时IQ组的对比敏感度也显著高于球面晶状体组(SN60AT组:P<0.01,SA60AT组:6.3degrees P<0.01,4.0degrees P<0.05).结论 非球面人工晶状体可以减少球面像差,提高低频尤其是眩光状态下的对比敏感度从而获得更好的视觉质量.滤蓝光晶状体与普通晶状体比较对比敏感度差异无统计学意义,不能明显改善视功能.