64层3D-CTA与3D-DSA对颅内动脉瘤评价的对比研究

目的 对比评价64层螺旋CT三维血管造影(3D-CTA)与三维数字减影血管造影(3D-DSA)对颅内动脉瘤的诊断价值.方法 28例临床怀疑颅内动脉瘤的患者均行64层螺旋CT血管造影和DSA,CT三维后处理主要包括容积重建(VR)及最大密度投影(MIP).常规二维DSA检查后,对可疑病变血管行旋转DSA检查,应用三维工作软件行3D后处理,比较3D-CTA与3D-DSA对动脉瘤显示的价值.结果 28例病例中22例CTA和DSA均显示动脉瘤并经手术或栓塞证实,其中1例CTA和DSA显示单个动脉瘤,手术证实为2个动脉瘤,1例CTA显示假阳性.3D-CTA与3D-DSA均能清楚显示动脉瘤形状、瘤径指向、瘤体直径、瘤颈、载瘤动脉、瘤体穿动脉情况,两者无明显差异.结论 64层3D-CTA在颅内动脉瘤诊断及细节显示上与3D-DSA无明显差异,一定程度上应能替代血管造影,指导临床治疗.     

16层螺旋CT血管造影在颅内动脉瘤破裂中的临床应用

目的通过与DSA和手术对照,探讨16层螺旋CT血管造影（CTA）在颅内动脉瘤破裂的临床应用价值。资料与方法对33例动脉瘤性蛛网膜下腔出血（SAH）、脑出血患者进行回顾性分析,33例均使用16层螺旋CT进行了CTA检查,其中18例行DSA检查;6例DSA下介入治疗,27例开颅行动脉瘤颈夹闭术;将CTA与DSA和术中所见对照。结果33例中,CTA共发现动脉瘤36个,其中18例行DSA检查者中,CTA发现动脉瘤20个,DSA发现动脉瘤21个;CTA能够清晰显示动脉瘤瘤体（形态、指向、轮廓）、瘤颈的宽度、载瘤动脉及与颅骨之间的关系;与DSA和手术对照,CTA对动脉瘤的检出率为95．2％,对破裂动脉瘤的诊断敏感性和特异性均为100％。结论16层螺旋CT脑血管造影重组图像质量高,安全、快速、无创,可以作为颅内动脉瘤破裂首选的筛检方法。     

CTA与DSA诊断颅内动脉瘤的对比研究

目的通过与DSA对比,评价三维CT血管造影在颅内动脉瘤诊断中的价值。方法对30例因蛛网膜下腔出血高度怀疑动脉瘤破裂的病人行CTA检查,同期行DSA检查及可行的血管内栓塞治疗。比较CTA与DSA检出动脉瘤的敏感性、特异性和准确性以及在显示动脉瘤瘤颈和载瘤动脉关系上的优劣。结果CTA检出动脉瘤26个,对动脉瘤的敏感性为95.5%,特异性为87.5%,准确性为93.3%,与DSA比较无显著差异。CTA对动脉瘤细节及瘤颈的显示明显优于DSA。结论CTA能无创有效的诊断颅内动脉瘤,所提供的诊断信息对治疗方案的制订具有极大的帮助,CTA还特别适用于急症病人的动脉瘤筛查。     

16层螺旋CT血管成像在颅内动脉瘤诊断和血管内治疗中的价值

目的 评价16层螺旋CT血管成像(CTA)在颅内动脉瘤诊断的准确性和确定其能否提供足够的诊断信息来指导血管内治疗.方法 329例临床怀疑颅内动脉瘤的患者纳入本研究,全部行CTA和DSA检查.运用最大密度投影和容积再现技术评价动脉瘤的形态、大小、位置和动脉瘤与周围血管的关系,并根据16层螺旋CTA结果选择血管内治疗或外科治疗.结果 329例中的181例患者发现202个颅内动脉瘤.4个动脉瘤CTA漏诊,而DSA检查过程中7个动脉瘤未能清楚显示.16层螺旋CTA诊断所有动脉瘤的敏感性、特异性和准确性分别是98%、98%和98%.16层螺旋CTA对于动脉瘤诊断的准确性与DSA的结果差别没有统计学意义.通过CTA评价认为115个动脉瘤适合行血管内治疗,结果112个动脉瘤成功栓塞.结论 16层螺旋CTA在诊断颅内动脉瘤方面有很高的准确性,能够提供有价值的信息指导动脉瘤的血管内治疗.     

多层螺旋CTA在颅内动脉瘤治疗前后应用价值的研究

目的：探讨多层螺旋CT血管成像（MSCTA）在颅内动脉瘤术前术后的应用价值。方法：回顾性分析38例行颅内动脉瘤治疗且治疗前后影像资料完整的病例资料,所有病例治疗前后均进行CTA检查,其中2例术后CTA复查两次。32例手术前后CTA检查相隔在10天之内,6例在11~27天之内。术前全部病例均DSA检查。结果：38例病例中颅内动脉瘤46个,其中行动脉瘤夹闭术34例,夹闭动脉瘤40个;介入栓塞术4例,栓塞动脉瘤4例;另有2个未作处理。46个动脉瘤CTA明确诊断40个,可疑5个,漏诊1个。术后CTA见夹闭不全2例,瘤颈残留1例。结论：MSCTA作为一种无创、快速、准确,易被患者接受的检查方法,不仅在颅内动脉瘤术前诊断及选择手术方法上具有优势,而且可成为术后随访的主要方法。     

多层螺旋CT血管造影对颅内动脉瘤的诊断价值

目的:探讨多层螺旋CT血管造影(CTA)对颅内动脉瘤的诊断价值。方法:对36例蛛网膜下腔出血(SAH)的动脉瘤疑似患者均行多层螺旋CT血管造影检查和数字减影血管造影(DSA)检查,将两种检查结果进行对照分析、比较优缺点,CTA后处理采用容积再现(VRT)、最大密度投影(MIP)和表面覆盖法(SSD)。CTA重建采用0.75mm层厚、0.7mm层间隔,延迟扫描时间采用提前监控、静脉团注法。两位放射专家用盲法分析CTA、DSA资料,对颅内动脉瘤作出诊断。结果:36例SAH病例中,CTA发现32例37个动脉瘤,包括前交通动脉瘤15个、大脑前动脉瘤2个、后交通支9个、颈内动脉4个、大脑中动脉主干5个、基底动脉2个,其中1例CTA检查为颈内动脉海绵窦段动脉瘤,直径<3mm,DSA检查为阴性,其余均经DSA证实。4例SAH病例CTA、DSA检查均为阴性。CTA能够清晰显示瘤体、瘤颈、载瘤动脉及毗邻关系,其敏感性为94.5%。动脉瘤直径大于3.0mm者,CTA、DSA检查结果基本一致。CTA以VRT重建效果最佳。结论:CTA对于动脉瘤疑似患者是一种安全、无创伤的检查技术,能够精确显示动脉瘤的空间关系,可作为颅内动脉瘤首选的诊断方法。     

16层螺旋CT血管造影在颅内动脉瘤诊断中的应用

目的：研究多层螺旋CT血管造影诊断颅内动脉瘤的应用价值。方法：16层螺旋CT机对怀疑有顷内动脉瘤的28例患者行CTA裣查，将啄始数据输入Vitrca2工作站，重建颅内血管三维图像，进行多平面重建（MPR）、容积重建（VR）、最大密度投影法（MIP）等后处理，并对照手术或介入栓塞结果评估其诊断价值。结果：MSCTA共发现28例33个动脉瘤，动脉瘤直径最小3mm，最大25mm。MSCTA能清晰显示动脉瘤的瘤体大小、瘤颈、载瘤动脉及其动脉瘤与临近血管分支和骨性组织间的空间关系。27例与手术／DSA结果一致。结论：MSCTA诊断颅内动脉瘤有较高准确性，可部分取代DSA造影检查。     

颅内动脉瘤破裂早期介入治疗的临床价值

目的探讨颅内动脉瘤破裂后早期行数字减影血管造影(DSA)诊断价值并介入栓塞治疗的临床价值。方法对在我院治疗的38例自发性蛛网膜下腔出血患者行头颅CT扫描及早期DSA检查,并行血管内微弹簧圈栓塞治疗及或手术夹闭,包括GDC34例,手术夹闭4例。38例患者按Hunt-Hess分级:Ⅰ级30例、Ⅱ级6例、Ⅲ级1例、Ⅳ级1例,所有病例均行DSA造影及CT扫描。结果 CT扫描均提示不同程度的自发性蛛网膜下腔出血;脑血管DSA造影诊断:前交通动脉瘤13例,后交通动脉瘤16例,大脑中动脉瘤7例,颈内动脉分叉部2例。介入栓塞及手术夹闭成功36例,占94.7%。36例随访3～35个月无再次出血,全部病例CT复查显示弹簧圈形态、位置无改变,30例6个月后复查DSA未见动脉瘤复发。2例后交通复杂动脉瘤介入栓塞失败,家属不愿手术治疗,他们分别于术后1周及1月后死亡。结论对颅内动脉瘤破裂患者需尽早行数字减影血管造影(DSA)作出早期诊断,早期进行弹簧圈血管内栓塞治疗;DSA在诊断,治疗及患者随访中均发挥非常重要的作用。     

16层螺旋CT血管造影在颅内动脉瘤中的应用价值

目的探讨16层螺旋CT血管造影(CTA)对颅内动脉瘤的诊断价值。方法28例疑有颅内动脉瘤患者均行16层CTA和DSA检查,对CTA的表现结合DSA和手术结果进行回顾性分析。结果本组28例经CTA共检出动脉瘤27个,其中25个经手术和DSA证实。1例CTA显示动脉瘤2个,DSA只显示1个,另1例CTA显示可疑动脉瘤2个,DSA显示正常。16层CTA诊断颅内动脉瘤的敏感性为89.2%,特异性为100%,准确性为96.4%。结论16层CTA在显示颅内动脉瘤方面可与DSA媲美,有重要临床应用价值。     

64层螺旋CT分别减影脑动脉混合脑动静脉和脑静脉血管成像在颅内自发性出血术前评估的价值

目的：探讨64层螺旋CT分别减影脑动脉、混合脑动静脉、脑静脉血管成像在自发性颅内出血术前评估价值。方法回顾分析同时行CT血管造影（CTA）和数字减影血管造影（DSA）检查的自发性颅内出血患者共215例。 CTA检查全部行64层螺旋CT平扫、增强动脉早期和静脉早期扫描,将动、静脉早期数据减去平扫数据分别重建动脉及混合动静脉,静脉早期数据减去动脉早期数据重建静脉。结果减影脑动脉、脑静脉血管图像去除了颅骨并且动脉、静脉无相互干扰,分别清晰显示动脉或静脉病变,混合脑动静脉则去除颅骨干扰且同时显示脑动静脉病变。215例颅内出血患者中14例CTA和DSA检查颅内均未见畸形血管,2例动脉瘤DSA发现而CTA未显示,3例动脉瘤CTA发现而DSA未显示。 CTA和DSA共同显示畸形血管196例,敏感性为99．9％,特异性为82．4％,其中动脉瘤179例,动静脉畸形9例,静脉瘤3例,烟雾病5例。结论64层螺旋CT分别减影脑动脉、混合脑动静脉、脑静脉血管成像在颅内出血检查,病变及周围结构显示清楚,对临床术前评估有较大意义,值得推广应用。     

CT angiography with three-dimensional techniques for the early diagnosis of intracranial aneurysms. Comparison with intra-arterial DSA and the surgical findings

INTRODUCTION: Cerebral CT angiography (CTA) is an established method applied to both the detection and treatment planning of intracranial aneurysms. The aim of our study was to compare CTA and digital subtraction angiography (DSA) findings with the surgical results mainly in patients with acute SAH and to evaluate the clinical usefulness of CTA. MATERIALS AND METHODS: During the last 2 years, 82 consecutive patients were admitted under clinical symptoms and signs suggestive of harboring an intracranial aneurysm. CT angiography performed immediately afterwards the plain CT, while DSA was performed within the first 48 h of admission. All aneurysms detected were confirmed during surgery or endovascular embolization. Repeat DSA was performed in all patients having both the initial CTA and the DSA 15 days after the onset of symptoms negative. CT angiograms and conventional angiographies were studied by a consensus of two radiologists for each technique, who performed aneurysm detection, morphological features characterization and evaluation of the technique. RESULTS: Surgical or/and endovascular treatment was performed in 45 patients and 53 aneurysms were confirmed. Using 3D-CT angiography, we detected 47 aneurysms in 42 patients. Conventional angiography depicted 43 aneurysms in 39 patients. The sensitivity of CTA for the detection of all aneurysms versus surgery was 88.7%, the specificity 100%, the positive predictive value (PPV) 100%, the negative predictive value (NPV) 80.7% and the accuracy 92.3%. Accordingly, the sensitivity of DSA was 87.8%, the specificity 98%, the PPV 97.7%, the NPV 89.1% and the accuracy 92.9%. Considering aneurysms > or =3 mm, CTA showed a sensitivity ranging from 93.3 to 100%, equal to that of DSA. CONCLUSION: Cerebral CT angiography has an equal sensitivity to DSA in the detection of intracranial aneurysms >3 mm. It has also 100% detection rate in AcoA and MCA bifurcation aneurysms, while some locations, like posterior communicating artery aneurysms, remain problematic. The delineating features of each aneurysm are better depicted with CTA due to 3D visualization. The use of digital subtraction angiography as a diagnostic tool can be limited in equivocal cases.     

Three-dimensional reconstructed rotational digital subtraction angiography in planning treatment of intracranial aneurysms

We evaluated three-dimensional (3D) reconstructions of 200 ° rotational digital subtraction angiography (DSA) images for their contributions to improving the safety of endovascular embolization of intracranial aneurysms. Standard DSA and 200 ° rotational DSA were performed in 40 adult patients (aged 21–77 years) with 45 intracranial aneurysms. Information obtainable from standard DSA and 3D-DSA images about aneurysm shape and size was compared. In 40 (89 %) of the 45 aneurysms 3D-DSA gave additional information about the anatomy of the aneurysm. In 17 (43 %) of these cases aneurysm anatomy could be visualized better on 3D-DSA than on standard DSA images. In three cases only 3D-DSA images showed blood vessels originating from the aneurysm. Reconstructed 3D images were also helpful in visualizing partially clipped aneurysms. On maximum-intensity projection images it was even possible to depict previously embolized aneurysms. Blood vessels originating from the aneurysm are visible on 3D-DSA images, and even previously clipped aneurysms can be visualized well. Rotational DSA with 3D reconstruction is a helpful tool in the assessment of intracranial aneurysms. Received: 7 September 1999; Revised: 26 November 1999; Accepted: 26 November 1999     

自发性蛛网膜下腔出血的CTA与DSA对比研究

目的:探讨64层CTA与DSA对自发性蛛网膜下腔出血(spontaneous subarachnoid hemorrhage,s-SAH)的应用价值及其限度。方法:收集153例s-SAH患者的CTA及DSA检查资料,回顾性分析2种检查方法的图像质量(采取1³分评分制),并比较2种方法在脑动脉瘤检出方面的灵敏度、特异度及准确度。结果:图像质量评分CTA为(2.63±0.262)分,DSA为(2.73±0.254)分,二者差异无统计学意义(P>0.05)。CTA对脑动脉瘤的检出的灵敏度为96.2%,特异度为94.9%,准确度为95.9%;DSA灵敏度为97.7%,特异度为97.4%,准确度为97.6%,二者差异无统计学意义(P>0.05)。结论:在s-SAH患者中,CTA与DSA均能准确检出动脉瘤所致破裂出血。相较于DSA,CTA能多方位显示病变,对血管壁及血管周围情况的显示更具价值。     

三维DSA与二维DSA在颅内动脉瘤诊断中价值的比较

目的：比较三维（3D）DSA与二维（2D）DSA）在颅内动脉瘤诊断中的价值。方法：22名疑为颅内动脉瘤的患者同行3D DSA和2D DSA检查,双盲法诊断3DDSA和2DDSA分别发现的动脉瘤的个数、动脉瘤与载瘤动脉和邻近血管的关系是否清楚,动脉瘤囊内有无穿支。结果：发现的30个动脉瘤中3D DSA的假生数和假阴性数均为0;2D DSA的假阳性数和假阴性数均为2个。3D DSA对30个动脉瘤和载瘤动脉及邻近血管的关系均显示清楚,发现2个动脉瘤囊内有穿支;2D DSA仅对8个动脉瘤（其中4个后交通动脉瘤,3个前交通动脉瘤和1个颈眼动脉瘤）和载瘤动脉及邻近血管的关系显示脉瘤（其中4个月后交通动脉瘤,个前交通动脉瘤和1个颈眼动脉瘤）和载瘤动脉及邻近血管的关系显示脉瘤（其中4个后交通过动脉瘤,3个前交通动脉瘤和1个颈眼动脉瘤）和载瘤动脉及邻近血管的关系显示清楚,无法证实动脉瘤囊内有无穿支。结论3D DSA在颅内动脉瘤的诊断方面明显优越于2D DSA。     

Intracranial aneurysms: role of multidetector CT angiography in diagnosis and endovascular therapy planning

PURPOSE: To evaluate the sensitivity of 16-detector row computed tomographic (CT) angiography in diagnosis of intracranial aneurysms and to determine whether multidetector CT angiography provides sufficient diagnostic information to guide endovascular treatment, with combined imaging and clinical data as the reference standard. MATERIALS AND METHODS: Institutional review board approval and informed consent were obtained. Eighty-seven patients clinically suspected of having subarachnoid hemorrhage underwent multidetector CT angiography and digital subtraction angiography (DSA). Aneurysm detection with multidetector CT angiography and DSA was analyzed on a per-patient and a per-aneurysm basis. For each aneurysm deemed ruptured on multidetector CT angiograms, the same multidetector CT angiography data set was used to determine whether the aneurysm was suitable for endovascular coil placement or whether a neurosurgical procedure was preferable. Criteria were based on neck width in relation to aneurysm size and the presence of vessels originating from the aneurysm. Results were compared with actual treatment that had been performed in each aneurysm after full diagnostic work-up, including DSA. Sensitivity, specificity, and positive and negative predictive values for aneurysm presence were determined. RESULTS: The reference standard revealed 84 aneurysms in 63 patients. Multidetector CT angiography was used to correctly identify 62 of 63 patients with 80 of 84 aneurysms and to correctly rule out aneurysms in 24 patients. DSA was used to correctly identify 62 of 63 patients with 79 of 84 aneurysms and to correctly rule out aneurysms in 23 patients. Per patient, the sensitivity, specificity, and positive and negative predictive values, respectively, for presence of aneurysm(s) were 98%, 100%, 100%, and 96% for multidetector CT angiography and 98%, 100%, 98%, and 96% for DSA. Per aneurysm, the possibility of coil embolization was correctly assessed with multidetector CT angiography in 69 (93%) of 74 target aneurysms for acute occlusive treatment. CONCLUSION: Multidetector CT angiography offers high diagnostic accuracy-equivalent to that of DSA-in the detection of intracranial aneurysms. Also, the possibility of coil embolization can be reliably determined with multidetector CT angiography.     

64层螺旋CT脑血管造影在颅内动脉瘤诊断中的应用

目的:与DSA相对照,探讨64层螺旋CT脑血管造影在颅内动脉瘤中的诊断价值。方法:对29例临床怀疑颅内动脉瘤的患者行64层螺旋CT脑血管造影(CTA)和DSA检查,使用GE64层Lightspeed VCT获得原始图像,所有病例均采用多层面重建(multiplanar reconstruction,MPR)、容积再现(volume rendering,VR)、薄层块最大密度投影(thin-slab maximumintensity projectjon,TS MIP)。后处理图像及DSA图像由2位放射科医生共同评估。结果:29例患者中,DSA证实25例共27个动脉瘤,其中2例为2个动脉瘤。与DSA结果相对照,CTA共检出25例26个动脉瘤,漏诊了1个颈出动脉瘤。CTA清晰显示了动脉瘤的形态、大小及载瘤动脉,3例动脉瘤瘤颈DSA未显示,CTA显示了全部动脉瘤的瘤颈。结论:64层CTA在颅内动脉瘤的诊断中具有极高价值,特别在显示动脉瘤瘤颈方面具有独特的优势,对临床治疗具有指导意义。     

微弹簧圈血管内介入治疗颅内动脉瘤

目的总结颅内动脉瘤血管内介入治疗的经验,探讨微弹簧圈栓塞颅内动脉瘤的技巧、效果及相关并发症的防治。方法回顾性分析我院介入治疗颅内动脉瘤31例,32个动脉瘤的临床资料,其中单纯用弹簧圈栓塞25例,宽颈动脉瘤球囊辅助弹簧圈栓塞4例,支架结合弹簧圈栓塞1例,载瘤动脉闭塞1例。结果栓塞程度:致密栓塞27例,疏松栓塞3例,闭塞载瘤动脉1例;术中动脉瘤破裂3例,术后完全康复22例,不同程度神经功能障碍8例,死亡1例。结论电解脱弹簧圈栓塞颅内动脉瘤,具有微创、安全、效果可靠等优点。选择合适的技术和方法,对提高栓塞率,减少并发症具有重要的意义。